UnivTrevesV1, PascalFrancis, Corpus, bibRecord, 000F64

Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions

Identifieur interne : 000F64 ( PascalFrancis/Corpus ); précédent : 000F63; suivant : 000F65

Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions

Auteurs : M. Augustin ; I. Zschocke ; N. Godau ; A. Buske-Kirschbaum ; M. Peschen ; B. Sommer ; G. Sattler

Source :

Dermatologic surgery [ 1076-0512 ] ; 1999.

RBID : Pascal:00-0032372

Descripteurs français

Pascal (Inist)
- Peau, Chirurgie, Anesthésie locale, Stress, Immunité, Angoisse anxiété, Trouble émotion, Psychosomatique, Homme, Etude statistique.

English descriptors

KwdEn :
- Anxiety, Emotional disorder, Human, Immunity, Local anesthesia, Psychosomatics, Skin, Statistical study, Stress, Surgery.

Abstract

BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56⁺ lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 1076-0512`
A03		`1`		`@0 Dermatol. surg.`
A05				`@2 25`
A06				`@2 11`
A08	`01`	`1`	`ENG`	`@1 Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions`
A11	`01`	`1`		`@1 AUGUSTIN (M.)`
A11	`02`	`1`		`@1 ZSCHOCKE (I.)`
A11	`03`	`1`		`@1 GODAU (N.)`
A11	`04`	`1`		`@1 BUSKE-KIRSCHBAUM (A.)`
A11	`05`	`1`		`@1 PESCHEN (M.)`
A11	`06`	`1`		`@1 SOMMER (B.)`
A11	`07`	`1`		`@1 SATTLER (G.)`
A14	`01`			`@1 Department of Dermatology, University Clinics of Freiburg @2 Freiburg @3 DEU @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 5 aut.`
A14	`02`			`@1 Department of Psychology, University of Trier @2 Trier @3 DEU @Z 4 aut.`
A14	`03`			`@1 Clinic of Dermatology @2 Darmstadt @3 DEU @Z 6 aut. @Z 7 aut.`
A14	`04`			`@1 Rosenparkklinik @2 Darmstadt @3 DEU @Z 6 aut. @Z 7 aut.`
A20				`@1 868-871`
A21				`@1 1999`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 17417 @5 354000080374500070`
A44				`@0 0000 @1 © 2000 INIST-CNRS. All rights reserved.`
A45				`@0 9 ref.`
A47	`01`	`1`		`@0 00-0032372`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 Dermatologic surgery`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56⁺ lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.
C02	`01`	`X`		`@0 002B25A`
C03	`01`	`X`	`FRE`	`@0 Peau @5 01`
C03	`01`	`X`	`ENG`	`@0 Skin @5 01`
C03	`01`	`X`	`SPA`	`@0 Piel @5 01`
C03	`02`	`X`	`FRE`	`@0 Chirurgie @5 02`
C03	`02`	`X`	`ENG`	`@0 Surgery @5 02`
C03	`02`	`X`	`SPA`	`@0 Cirugía @5 02`
C03	`03`	`X`	`FRE`	`@0 Anesthésie locale @5 03`
C03	`03`	`X`	`ENG`	`@0 Local anesthesia @5 03`
C03	`03`	`X`	`SPA`	`@0 Anestesia local @5 03`
C03	`04`	`X`	`FRE`	`@0 Stress @5 04`
C03	`04`	`X`	`ENG`	`@0 Stress @5 04`
C03	`04`	`X`	`SPA`	`@0 Stress @5 04`
C03	`05`	`X`	`FRE`	`@0 Immunité @5 05`
C03	`05`	`X`	`ENG`	`@0 Immunity @5 05`
C03	`05`	`X`	`SPA`	`@0 Inmunidad @5 05`
C03	`06`	`X`	`FRE`	`@0 Angoisse anxiété @5 06`
C03	`06`	`X`	`ENG`	`@0 Anxiety @5 06`
C03	`06`	`X`	`SPA`	`@0 Angustia ansiedad @5 06`
C03	`07`	`X`	`FRE`	`@0 Trouble émotion @5 07`
C03	`07`	`X`	`ENG`	`@0 Emotional disorder @5 07`
C03	`07`	`X`	`SPA`	`@0 Trastorno emocíon @5 07`
C03	`08`	`X`	`FRE`	`@0 Psychosomatique @5 08`
C03	`08`	`X`	`ENG`	`@0 Psychosomatics @5 08`
C03	`08`	`X`	`SPA`	`@0 Psicosomática @5 08`
C03	`09`	`X`	`FRE`	`@0 Homme @5 09`
C03	`09`	`X`	`ENG`	`@0 Human @5 09`
C03	`09`	`X`	`SPA`	`@0 Hombre @5 09`
C03	`10`	`X`	`FRE`	`@0 Etude statistique @5 20`
C03	`10`	`X`	`ENG`	`@0 Statistical study @5 20`
C03	`10`	`X`	`SPA`	`@0 Estudio estadístico @5 20`
C07	`01`	`X`	`FRE`	`@0 Peau pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Skin disease @5 37`
C07	`01`	`X`	`SPA`	`@0 Piel patología @5 37`
N21				`@1 024`

Format Inist (serveur)

NO :	PASCAL 00-0032372 INIST
ET :	Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions
AU :	AUGUSTIN (M.); ZSCHOCKE (I.); GODAU (N.); BUSKE-KIRSCHBAUM (A.); PESCHEN (M.); SOMMER (B.); SATTLER (G.)
AF :	Department of Dermatology, University Clinics of Freiburg/Freiburg/Allemagne (1 aut., 2 aut., 3 aut., 5 aut.); Department of Psychology, University of Trier/Trier/Allemagne (4 aut.); Clinic of Dermatology/Darmstadt/Allemagne (6 aut., 7 aut.); Rosenparkklinik/Darmstadt/Allemagne (6 aut., 7 aut.)
DT :	Publication en série; Niveau analytique
SO :	Dermatologic surgery; ISSN 1076-0512; Etats-Unis; Da. 1999; Vol. 25; No. 11; Pp. 868-871; Bibl. 9 ref.
LA :	Anglais
EA :	BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56⁺ lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.
CC :	002B25A
FD :	Peau; Chirurgie; Anesthésie locale; Stress; Immunité; Angoisse anxiété; Trouble émotion; Psychosomatique; Homme; Etude statistique
FG :	Peau pathologie
ED :	Skin; Surgery; Local anesthesia; Stress; Immunity; Anxiety; Emotional disorder; Psychosomatics; Human; Statistical study
EG :	Skin disease
SD :	Piel; Cirugía; Anestesia local; Stress; Inmunidad; Angustia ansiedad; Trastorno emocíon; Psicosomática; Hombre; Estudio estadístico
LO :	INIST-17417.354000080374500070
ID :	00-0032372

Links to Exploration step

Pascal:00-0032372

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions</title>
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<author><name sortKey="Peschen, M" sort="Peschen, M" uniqKey="Peschen M" first="M." last="Peschen">M. Peschen</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anxiety</term>
<term>Emotional disorder</term>
<term>Human</term>
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<term>Psychosomatics</term>
<term>Skin</term>
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<term>Stress</term>
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<keywords scheme="Pascal" xml:lang="fr"><term>Peau</term>
<term>Chirurgie</term>
<term>Anesthésie locale</term>
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<term>Immunité</term>
<term>Angoisse anxiété</term>
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<front><div type="abstract" xml:lang="en">BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56<sup>+</sup>
 lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.</div>
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<fA14 i1="01"><s1>Department of Dermatology, University Clinics of Freiburg</s1>
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<fA14 i1="02"><s1>Department of Psychology, University of Trier</s1>
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<fC01 i1="01" l="ENG"><s0>BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56<sup>+</sup>
 lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B25A</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Peau</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Skin</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Piel</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Chirurgie</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Surgery</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Cirugía</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Anesthésie locale</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Local anesthesia</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Anestesia local</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Stress</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Stress</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Stress</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Immunité</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Immunity</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Inmunidad</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Angoisse anxiété</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Anxiety</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Angustia ansiedad</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Trouble émotion</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Emotional disorder</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Trastorno emocíon</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Psychosomatique</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Psychosomatics</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Psicosomática</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Homme</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Human</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Hombre</s0>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Etude statistique</s0>
<s5>20</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Statistical study</s0>
<s5>20</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Estudio estadístico</s0>
<s5>20</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Peau pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Skin disease</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Piel patología</s0>
<s5>37</s5>
</fC07>
<fN21><s1>024</s1>
</fN21>
</pA>
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<server><NO>PASCAL 00-0032372 INIST</NO>
<ET>Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions</ET>
<AU>AUGUSTIN (M.); ZSCHOCKE (I.); GODAU (N.); BUSKE-KIRSCHBAUM (A.); PESCHEN (M.); SOMMER (B.); SATTLER (G.)</AU>
<AF>Department of Dermatology, University Clinics of Freiburg/Freiburg/Allemagne (1 aut., 2 aut., 3 aut., 5 aut.); Department of Psychology, University of Trier/Trier/Allemagne (4 aut.); Clinic of Dermatology/Darmstadt/Allemagne (6 aut., 7 aut.); Rosenparkklinik/Darmstadt/Allemagne (6 aut., 7 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Dermatologic surgery; ISSN 1076-0512; Etats-Unis; Da. 1999; Vol. 25; No. 11; Pp. 868-871; Bibl. 9 ref.</SO>
<LA>Anglais</LA>
<EA>BACKGROUND. Although excision of nevi under local anesthesia is a frequent and harmless operation, it apparently causes increased stress in many patients. However, thus far no studies have focused on the question of whether there are measurable effects on psychological, physiological, and immunological parameters. OBJECTIVE. To assess the perioperative stress reactions of patients undergoing skin surgery under local anesthesia for nevo-cellular nevi. METHODS. Fifty consecutive patients with pigmented nevi were examined at five points of measurement: 1 week and 30 minutes before the operation, during the operation, 30 minutes and 1 week after the operation. Somatic parameters included blood pressure, pulse, respiratory rate, and the level of pain. Lymphocyte subpopulations, white blood cell count, and cortisol in saliva were determined. Anxiety and general psychological distress were evaluated with validated questionnaires. RESULTS. There was a significant increase in anxiety at the time of surgery. In parallel, the physiological parameters as well as the CD56<sup>+</sup>
 lymphocytes changed significantly. Preoperation anxiety and intraoperation pain were significantly higher in women (P <.001), but did not depend on age. CONCLUSION. There appears to be an interaction between physiological and emotional components in the operative stress reaction under local anesthesia. In patients with skin cancer, the perioperative stress may lead to transient impairment of immune function.</EA>
<CC>002B25A</CC>
<FD>Peau; Chirurgie; Anesthésie locale; Stress; Immunité; Angoisse anxiété; Trouble émotion; Psychosomatique; Homme; Etude statistique</FD>
<FG>Peau pathologie</FG>
<ED>Skin; Surgery; Local anesthesia; Stress; Immunity; Anxiety; Emotional disorder; Psychosomatics; Human; Statistical study</ED>
<EG>Skin disease</EG>
<SD>Piel; Cirugía; Anestesia local; Stress; Inmunidad; Angustia ansiedad; Trastorno emocíon; Psicosomática; Hombre; Estudio estadístico</SD>
<LO>INIST-17417.354000080374500070</LO>
<ID>00-0032372</ID>
</server>
</inist>
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Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions

Skin surgery under local anesthesia leads to stress-induced alterations of psychological, physical, and immune functions

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