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Expressionsanalysen bei der rheumatoiden Arthritis : Rheumapathologie

Identifieur interne : 000855 ( PascalFrancis/Corpus ); précédent : 000854; suivant : 000856

Expressionsanalysen bei der rheumatoiden Arthritis : Rheumapathologie

Auteurs : R. Guenther ; V. Krenn ; T. H Upl

Source :

RBID : Pascal:08-0124913

Descripteurs français

English descriptors

Abstract

Inflammatory rheumatic diseases with their unclear aetiology are a challenge for the routine clinical practice. The dominating inflammatory processes with many facets of autoimmune phenomena have been extensively studied during the last decades. Modern high throughput technologies provide for the first time the opportunity to obtain an insight into the many different molecular aspects in one patient in parallel. Step by step, concepts can be developed to understand the relationships and interdependencies of the molecular processes and to place them in order of importance for each individual separately. Thus, studies have demonstrated that the risk of disease severity can be estimated and the response to therapy can be objectified based on molecular investigations. Exemplarily, the potential has been demonstrated that the therapeutic outcome towards a defined treatment may be predicted. Despite the high cost, it is becoming more and more obvious that an extensive increase of knowledge depends on the detection of a multitude of parameters, a task which will need to be accomplished in the near future.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0340-1855
A02 01      @0 ZRHMBQ
A03   1    @0 Z. Rheumatol. : (Print)
A05       @2 67
A06       @2 1
A08 01  1  GER  @1 Expressionsanalysen bei der rheumatoiden Arthritis : Rheumapathologie
A11 01  1    @1 GUENTHER (R.)
A11 02  1    @1 KRENN (V.)
A11 03  1    @1 HÄUPL (T.)
A14 01      @1 Institut für Pathologie, Charité Universitätsmedizin Berlin @3 DEU @Z 1 aut.
A14 02      @1 Institut für Pathologie @2 Trier @3 DEU @Z 2 aut.
A14 03      @1 Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité Universitätsmedizin Berlin @3 DEU @Z 3 aut.
A20       @2 17-24 [7 p.]
A21       @1 2008
A23 01      @0 GER
A24 01      @0 eng
A43 01      @1 INIST @2 6410 @5 354000161940870020
A44       @0 0000 @1 © 2008 INIST-CNRS. All rights reserved.
A45       @0 43 ref.
A47 01  1    @0 08-0124913
A60       @1 P
A61       @0 A
A64 01  1    @0 Zeitschrift für Rheumatologie : (Print)
A66 01      @0 DEU
A68 01  1  ENG  @1 Expression analyses for rheumatoid arthritis
C01 01    ENG  @0 Inflammatory rheumatic diseases with their unclear aetiology are a challenge for the routine clinical practice. The dominating inflammatory processes with many facets of autoimmune phenomena have been extensively studied during the last decades. Modern high throughput technologies provide for the first time the opportunity to obtain an insight into the many different molecular aspects in one patient in parallel. Step by step, concepts can be developed to understand the relationships and interdependencies of the molecular processes and to place them in order of importance for each individual separately. Thus, studies have demonstrated that the risk of disease severity can be estimated and the response to therapy can be objectified based on molecular investigations. Exemplarily, the potential has been demonstrated that the therapeutic outcome towards a defined treatment may be predicted. Despite the high cost, it is becoming more and more obvious that an extensive increase of knowledge depends on the detection of a multitude of parameters, a task which will need to be accomplished in the near future.
C02 01  X    @0 002B15D
C03 01  X  FRE  @0 Polyarthrite rhumatoïde @5 01
C03 01  X  ENG  @0 Rheumatoid arthritis @5 01
C03 01  X  SPA  @0 Poliartritis reumatoidea @5 01
C03 02  X  FRE  @0 Synovite @5 02
C03 02  X  ENG  @0 Synovitis @5 02
C03 02  X  SPA  @0 Sinovitis @5 02
C03 03  X  FRE  @0 Echelle d'évaluation @5 07
C03 03  X  ENG  @0 Evaluation scale @5 07
C03 03  X  SPA  @0 Escala evaluación @5 07
C03 04  X  FRE  @0 Expression génique @5 08
C03 04  X  ENG  @0 Gene expression @5 08
C03 04  X  SPA  @0 Expresión genética @5 08
C03 05  X  FRE  @0 Chronique @5 30
C03 05  X  ENG  @0 Chronic @5 30
C03 05  X  SPA  @0 Crónico @5 30
C07 01  X  FRE  @0 Maladie autoimmune @5 37
C07 01  X  ENG  @0 Autoimmune disease @5 37
C07 01  X  SPA  @0 Enfermedad autoinmune @5 37
C07 02  X  FRE  @0 Rhumatisme inflammatoire @5 38
C07 02  X  ENG  @0 Inflammatory joint disease @5 38
C07 02  X  SPA  @0 Reumatismo inflamatorio @5 38
C07 03  X  FRE  @0 Pathologie du système ostéoarticulaire @5 39
C07 03  X  ENG  @0 Diseases of the osteoarticular system @5 39
C07 03  X  SPA  @0 Sistema osteoarticular patología @5 39
C07 04  X  FRE  @0 Immunopathologie @5 40
C07 04  X  ENG  @0 Immunopathology @5 40
C07 04  X  SPA  @0 Inmunopatología @5 40
N21       @1 070
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 08-0124913 INIST
ET : (Expression analyses for rheumatoid arthritis)
GT : Expressionsanalysen bei der rheumatoiden Arthritis : Rheumapathologie
AU : GUENTHER (R.); KRENN (V.); HÄUPL (T.)
AF : Institut für Pathologie, Charité Universitätsmedizin Berlin/Allemagne (1 aut.); Institut für Pathologie/Trier/Allemagne (2 aut.); Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité Universitätsmedizin Berlin/Allemagne (3 aut.)
DT : Publication en série; Niveau analytique
SO : Zeitschrift für Rheumatologie : (Print); ISSN 0340-1855; Coden ZRHMBQ; Allemagne; Da. 2008; Vol. 67; No. 1; 17-24 [7 p.]; Abs. anglais; Bibl. 43 ref.
LA : Allemand
EA : Inflammatory rheumatic diseases with their unclear aetiology are a challenge for the routine clinical practice. The dominating inflammatory processes with many facets of autoimmune phenomena have been extensively studied during the last decades. Modern high throughput technologies provide for the first time the opportunity to obtain an insight into the many different molecular aspects in one patient in parallel. Step by step, concepts can be developed to understand the relationships and interdependencies of the molecular processes and to place them in order of importance for each individual separately. Thus, studies have demonstrated that the risk of disease severity can be estimated and the response to therapy can be objectified based on molecular investigations. Exemplarily, the potential has been demonstrated that the therapeutic outcome towards a defined treatment may be predicted. Despite the high cost, it is becoming more and more obvious that an extensive increase of knowledge depends on the detection of a multitude of parameters, a task which will need to be accomplished in the near future.
CC : 002B15D
FD : Polyarthrite rhumatoïde; Synovite; Echelle d'évaluation; Expression génique; Chronique
FG : Maladie autoimmune; Rhumatisme inflammatoire; Pathologie du système ostéoarticulaire; Immunopathologie
ED : Rheumatoid arthritis; Synovitis; Evaluation scale; Gene expression; Chronic
EG : Autoimmune disease; Inflammatory joint disease; Diseases of the osteoarticular system; Immunopathology
SD : Poliartritis reumatoidea; Sinovitis; Escala evaluación; Expresión genética; Crónico
LO : INIST-6410.354000161940870020
ID : 08-0124913

Links to Exploration step

Pascal:08-0124913

Le document en format XML

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