Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder
Identifieur interne : 000332 ( Ncbi/Merge ); précédent : 000331; suivant : 000333Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder
Auteurs : Kaixin Zhou [Royaume-Uni] ; Astrid Dempfle [Allemagne] ; Mauricio Arcos-Burgos [États-Unis] ; Steven C. Bakker [Pays-Bas] ; Tobias Banaschewski [Allemagne] ; Joseph Biederman [États-Unis] ; Jan Buitelaar [Pays-Bas] ; F. Xavier Castellanos [États-Unis] ; Alysa Doyle [États-Unis] ; Richard P. Ebstein [Israël] ; Jenny Ekholm [États-Unis] ; Paola Forabosco [Royaume-Uni, Italie] ; Barbara Franke [Pays-Bas] ; Christine Freitag [Allemagne] ; Susann Friedel [Allemagne] ; Michael Gill [Irlande (pays)] ; Johannes Hebebrand [Allemagne] ; Anke Hinney [Allemagne] ; Christian Jacob [Allemagne] ; Klaus Peter Lesch [Allemagne] ; Sandra K. Loo [États-Unis] ; Francisco Lopera [Colombie] ; James T. Mccracken [États-Unis] ; James J. Mcgough [États-Unis] ; Jobst Meyer [Allemagne] ; Eric Mick [États-Unis] ; Ana Miranda [Espagne] ; Maximilian Muenke [Royaume-Uni, États-Unis] ; Fernando Mulas [Espagne] ; Stanley F. Nelson [États-Unis] ; T. Trang Nguyen [Allemagne] ; Robert D. Oades [Allemagne] ; Matthew N. Ogdie [États-Unis] ; Juan David Palacio [Colombie] ; David Pineda [Colombie] ; Andreas Reif [Allemagne] ; Tobias J. Renner [Allemagne] ; Herbert Roeyers [Belgique] ; Marcel Romanos [Allemagne] ; Aribert Rothenberger [Allemagne] ; Helmut Sch Fer [Allemagne] ; Joseph Sergeant [Pays-Bas] ; Richard J. Sinke [Pays-Bas] ; Susan L. Smalley [États-Unis] ; Edmund Sonuga-Barke [Royaume-Uni, États-Unis] ; Hans-Christoph Steinhausen [Suisse] ; Emma Van Der Meulen [Pays-Bas] ; Susanne Walitza [Allemagne] ; Andreas Warnke [Allemagne] ; Cathryn M. Lewis [Royaume-Uni] ; Stephen V. Faraone [États-Unis] ; Philip Asherson [Royaume-Uni]Source :
- American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics [ 1552-4841 ] ; 2008.
Abstract
Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (
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DOI: 10.1002/ajmg.b.30878
PubMed: 18988193
PubMed Central: 2890047
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xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Istituto di Genetica delle Popolazioni—CNR, Alghero, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Genetica delle Popolazioni—CNR, Alghero</wicri:regionArea><wicri:noRegion>Alghero</wicri:noRegion></affiliation></author><author><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><affiliation wicri:level="3"><nlm:aff id="A8">Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen, The Netherlands</nlm:aff><country 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Psychiatry, Saarland University Hospital, Homburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Friedel, Susann" sort="Friedel, Susann" uniqKey="Friedel S" first="Susann" last="Friedel">Susann Friedel</name><affiliation wicri:level="1"><nlm:aff id="A16">Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Gill, Michael" 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Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Hinney, Anke" sort="Hinney, Anke" uniqKey="Hinney A" first="Anke" last="Hinney">Anke Hinney</name><affiliation wicri:level="1"><nlm:aff id="A16">Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Jacob, Christian" sort="Jacob, Christian" uniqKey="Jacob C" first="Christian" last="Jacob">Christian Jacob</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Lesch, Klaus Peter" sort="Lesch, Klaus Peter" uniqKey="Lesch K" first="Klaus Peter" last="Lesch">Klaus Peter Lesch</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Loo, Sandra K" sort="Loo, Sandra K" uniqKey="Loo S" first="Sandra K." last="Loo">Sandra K. Loo</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Lopera, Francisco" sort="Lopera, Francisco" uniqKey="Lopera F" first="Francisco" last="Lopera">Francisco Lopera</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Mccracken, James T" sort="Mccracken, James T" uniqKey="Mccracken J" first="James T." last="Mccracken">James T. Mccracken</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Mcgough, James J" sort="Mcgough, James J" uniqKey="Mcgough J" first="James J." last="Mcgough">James J. Mcgough</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Meyer, Jobst" sort="Meyer, Jobst" uniqKey="Meyer J" first="Jobst" last="Meyer">Jobst Meyer</name><affiliation wicri:level="4"><nlm:aff id="A21">Department of Neurobehavioral Genetics, University of Trier, Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurobehavioral Genetics, University of Trier, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><orgName type="university">Université de Trèves</orgName><placeName><settlement type="city">Trèves (Allemagne)</settlement><region type="land" nuts="1">Rhénanie-Palatinat</region></placeName></affiliation></author><author><name sortKey="Mick, Eric" sort="Mick, Eric" uniqKey="Mick E" first="Eric" last="Mick">Eric Mick</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Miranda, Ana" sort="Miranda, Ana" uniqKey="Miranda A" first="Ana" last="Miranda">Ana Miranda</name><affiliation wicri:level="1"><nlm:aff id="A22">Department of Developmental and Educational Psychology, University of Valencia, Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Developmental and Educational Psychology, University of Valencia, Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Muenke, Maximilian" sort="Muenke, Maximilian" uniqKey="Muenke M" first="Maximilian" last="Muenke">Maximilian Muenke</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Mulas, Fernando" sort="Mulas, Fernando" uniqKey="Mulas F" first="Fernando" last="Mulas">Fernando Mulas</name><affiliation wicri:level="1"><nlm:aff id="A23">Department of Neuropaediatric, La Fe University Hospital, Faculty of Medicine, Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neuropaediatric, La Fe University Hospital, Faculty of Medicine, Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Nelson, Stanley F" sort="Nelson, Stanley F" uniqKey="Nelson S" first="Stanley F." last="Nelson">Stanley F. Nelson</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Human Genetics, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Human Genetics, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Nguyen, T Trang" sort="Nguyen, T Trang" uniqKey="Nguyen T" first="T. Trang" last="Nguyen">T. Trang Nguyen</name><affiliation wicri:level="3"><nlm:aff id="A2">Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Oades, Robert D" sort="Oades, Robert D" uniqKey="Oades R" first="Robert D." last="Oades">Robert D. Oades</name><affiliation wicri:level="1"><nlm:aff id="A24">University Clinic for Child and Adolescent Psychiatry, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Clinic for Child and Adolescent Psychiatry, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Ogdie, Matthew N" sort="Ogdie, Matthew N" uniqKey="Ogdie M" first="Matthew N." last="Ogdie">Matthew N. Ogdie</name><affiliation wicri:level="2"><nlm:aff id="A25">The Broad Institute, MIT, Cambridge, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>The Broad Institute, MIT, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Palacio, Juan David" sort="Palacio, Juan David" uniqKey="Palacio J" first="Juan David" last="Palacio">Juan David Palacio</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Pineda, David" sort="Pineda, David" uniqKey="Pineda D" first="David" last="Pineda">David Pineda</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Reif, Andreas" sort="Reif, Andreas" uniqKey="Reif A" first="Andreas" last="Reif">Andreas Reif</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Renner, Tobias J" sort="Renner, Tobias J" uniqKey="Renner T" first="Tobias J." last="Renner">Tobias J. Renner</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Roeyers, Herbert" sort="Roeyers, Herbert" uniqKey="Roeyers H" first="Herbert" last="Roeyers">Herbert Roeyers</name><affiliation wicri:level="4"><nlm:aff id="A27">Ghent University, Dunantlaan, Ghent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Ghent University, Dunantlaan, Ghent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Romanos, Marcel" sort="Romanos, Marcel" uniqKey="Romanos M" first="Marcel" last="Romanos">Marcel Romanos</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name><affiliation wicri:level="1"><nlm:aff id="A28">Child and Adolescent Psychiatry, University of Gottingen, Gottingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Child and Adolescent Psychiatry, University of Gottingen, Gottingen</wicri:regionArea><wicri:noRegion>Gottingen</wicri:noRegion><wicri:noRegion>Gottingen</wicri:noRegion><wicri:noRegion>Gottingen</wicri:noRegion></affiliation></author><author><name sortKey="Sch Fer, Helmut" sort="Sch Fer, Helmut" uniqKey="Sch Fer H" first="Helmut" last="Sch Fer">Helmut Sch Fer</name><affiliation wicri:level="3"><nlm:aff id="A2">Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Sergeant, Joseph" sort="Sergeant, Joseph" uniqKey="Sergeant J" first="Joseph" last="Sergeant">Joseph Sergeant</name><affiliation wicri:level="3"><nlm:aff id="A29">Vrije Universiteit, De Boelelaan, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Vrije Universiteit, De Boelelaan, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Sinke, Richard J" sort="Sinke, Richard J" uniqKey="Sinke R" first="Richard J." last="Sinke">Richard J. Sinke</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Smalley, Susan L" sort="Smalley, Susan L" uniqKey="Smalley S" first="Susan L." last="Smalley">Susan L. Smalley</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A30">Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Sonuga Barke, Edmund" sort="Sonuga Barke, Edmund" uniqKey="Sonuga Barke E" first="Edmund" last="Sonuga-Barke">Edmund Sonuga-Barke</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Child Study Center, New York University, New York, New York</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Child Study Center, New York University, New York</wicri:cityArea></affiliation><affiliation wicri:level="1"><nlm:aff id="A31">School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Steinhausen, Hans Christoph" sort="Steinhausen, Hans Christoph" uniqKey="Steinhausen H" first="Hans-Christoph" last="Steinhausen">Hans-Christoph Steinhausen</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Zurich, Zurich</wicri:regionArea><orgName type="university">Université de Zurich</orgName><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Van Der Meulen, Emma" sort="Van Der Meulen, Emma" uniqKey="Van Der Meulen E" first="Emma" last="Van Der Meulen">Emma Van Der Meulen</name><affiliation wicri:level="3"><nlm:aff id="A33">Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Walitza, Susanne" sort="Walitza, Susanne" uniqKey="Walitza S" first="Susanne" last="Walitza">Susanne Walitza</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Warnke, Andreas" sort="Warnke, Andreas" uniqKey="Warnke A" first="Andreas" last="Warnke">Andreas Warnke</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Lewis, Cathryn M" sort="Lewis, Cathryn M" uniqKey="Lewis C" first="Cathryn M" last="Lewis">Cathryn M. Lewis</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A12">Department of Medical and Molecular Genetics, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Psychiatry, SUNY Upstate Medical University, Syracuse</wicri:cityArea></affiliation></author><author><name sortKey="Asherson, Philip" sort="Asherson, Philip" uniqKey="Asherson P" first="Philip" last="Asherson">Philip Asherson</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18988193</idno><idno type="pmc">2890047</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890047</idno><idno type="RBID">PMC:2890047</idno><idno type="doi">10.1002/ajmg.b.30878</idno><date when="2008">2008</date><idno type="wicri:Area/Pmc/Corpus">000091</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000091</idno><idno type="wicri:Area/Pmc/Curation">000091</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000091</idno><idno type="wicri:Area/Pmc/Checkpoint">000167</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000167</idno><idno type="wicri:Area/Ncbi/Merge">000332</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder</title><author><name sortKey="Zhou, Kaixin" sort="Zhou, Kaixin" uniqKey="Zhou K" first="Kaixin" last="Zhou">Kaixin Zhou</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Dempfle, Astrid" sort="Dempfle, Astrid" uniqKey="Dempfle A" first="Astrid" last="Dempfle">Astrid Dempfle</name><affiliation wicri:level="3"><nlm:aff id="A2">Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Arcos Burgos, Mauricio" sort="Arcos Burgos, Mauricio" uniqKey="Arcos Burgos M" first="Mauricio" last="Arcos-Burgos">Mauricio Arcos-Burgos</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Psychiatry and Behavioral Sciences, Leonard M. Miller School of Medicine, University of Miami, Miami, Florida</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Floride</region></placeName><wicri:cityArea>Department of Psychiatry and Behavioral Sciences, Leonard M. Miller School of Medicine, University of Miami, Miami</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Bakker, Steven C" sort="Bakker, Steven C" uniqKey="Bakker S" first="Steven C." last="Bakker">Steven C. Bakker</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Banaschewski, Tobias" sort="Banaschewski, Tobias" uniqKey="Banaschewski T" first="Tobias" last="Banaschewski">Tobias Banaschewski</name><affiliation wicri:level="3"><nlm:aff id="A6">Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Mannheim</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Mannheim</settlement></placeName></affiliation></author><author><name sortKey="Biederman, Joseph" sort="Biederman, Joseph" uniqKey="Biederman J" first="Joseph" last="Biederman">Joseph Biederman</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Buitelaar, Jan" sort="Buitelaar, Jan" uniqKey="Buitelaar J" first="Jan" last="Buitelaar">Jan Buitelaar</name><affiliation wicri:level="3"><nlm:aff id="A8">Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Castellanos, F Xavier" sort="Castellanos, F Xavier" uniqKey="Castellanos F" first="F. Xavier" last="Castellanos">F. Xavier Castellanos</name><affiliation wicri:level="2"><nlm:aff id="A9">Child Study Center, New York University, New York, New York</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Child Study Center, New York University, New York</wicri:cityArea></affiliation></author><author><name sortKey="Doyle, Alysa" sort="Doyle, Alysa" uniqKey="Doyle A" first="Alysa" last="Doyle">Alysa Doyle</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Ebstein, Richard P" sort="Ebstein, Richard P" uniqKey="Ebstein R" first="Richard P." last="Ebstein">Richard P. Ebstein</name><affiliation wicri:level="1"><nlm:aff id="A10">Geha MHC, Petach-Tikva, Israel</nlm:aff><country xml:lang="fr">Israël</country><wicri:regionArea>Geha MHC, Petach-Tikva</wicri:regionArea><wicri:noRegion>Petach-Tikva</wicri:noRegion></affiliation></author><author><name sortKey="Ekholm, Jenny" sort="Ekholm, Jenny" uniqKey="Ekholm J" first="Jenny" last="Ekholm">Jenny Ekholm</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Human Genetics, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Human Genetics, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Forabosco, Paola" sort="Forabosco, Paola" uniqKey="Forabosco P" first="Paola" last="Forabosco">Paola Forabosco</name><affiliation wicri:level="3"><nlm:aff id="A12">Department of Medical and Molecular Genetics, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="A13">Istituto di Genetica delle Popolazioni—CNR, Alghero, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Istituto di Genetica delle Popolazioni—CNR, Alghero</wicri:regionArea><wicri:noRegion>Alghero</wicri:noRegion></affiliation></author><author><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><affiliation wicri:level="3"><nlm:aff id="A8">Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A14">Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen</wicri:regionArea><placeName><settlement type="city">Nimègue</settlement><region type="province" nuts="2">Gueldre</region></placeName></affiliation></author><author><name sortKey="Freitag, Christine" sort="Freitag, Christine" uniqKey="Freitag C" first="Christine" last="Freitag">Christine Freitag</name><affiliation wicri:level="1"><nlm:aff id="A15">Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg</wicri:regionArea><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion><wicri:noRegion>Homburg</wicri:noRegion></affiliation></author><author><name sortKey="Friedel, Susann" sort="Friedel, Susann" uniqKey="Friedel S" first="Susann" last="Friedel">Susann Friedel</name><affiliation wicri:level="1"><nlm:aff id="A16">Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name><affiliation wicri:level="1"><nlm:aff id="A17">Department of Psychiatry, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland</nlm:aff><country xml:lang="fr">Irlande (pays)</country><wicri:regionArea>Department of Psychiatry, Trinity Centre for Health Sciences, St. James's Hospital, Dublin</wicri:regionArea><wicri:noRegion>Dublin</wicri:noRegion></affiliation></author><author><name sortKey="Hebebrand, Johannes" sort="Hebebrand, Johannes" uniqKey="Hebebrand J" first="Johannes" last="Hebebrand">Johannes Hebebrand</name><affiliation wicri:level="1"><nlm:aff id="A16">Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Hinney, Anke" sort="Hinney, Anke" uniqKey="Hinney A" first="Anke" last="Hinney">Anke Hinney</name><affiliation wicri:level="1"><nlm:aff id="A16">Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Jacob, Christian" sort="Jacob, Christian" uniqKey="Jacob C" first="Christian" last="Jacob">Christian Jacob</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Lesch, Klaus Peter" sort="Lesch, Klaus Peter" uniqKey="Lesch K" first="Klaus Peter" last="Lesch">Klaus Peter Lesch</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Loo, Sandra K" sort="Loo, Sandra K" uniqKey="Loo S" first="Sandra K." last="Loo">Sandra K. Loo</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Lopera, Francisco" sort="Lopera, Francisco" uniqKey="Lopera F" first="Francisco" last="Lopera">Francisco Lopera</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Mccracken, James T" sort="Mccracken, James T" uniqKey="Mccracken J" first="James T." last="Mccracken">James T. Mccracken</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Mcgough, James J" sort="Mcgough, James J" uniqKey="Mcgough J" first="James J." last="Mcgough">James J. Mcgough</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Meyer, Jobst" sort="Meyer, Jobst" uniqKey="Meyer J" first="Jobst" last="Meyer">Jobst Meyer</name><affiliation wicri:level="4"><nlm:aff id="A21">Department of Neurobehavioral Genetics, University of Trier, Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Neurobehavioral Genetics, University of Trier, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><orgName type="university">Université de Trèves</orgName><placeName><settlement type="city">Trèves (Allemagne)</settlement><region type="land" nuts="1">Rhénanie-Palatinat</region></placeName></affiliation></author><author><name sortKey="Mick, Eric" sort="Mick, Eric" uniqKey="Mick E" first="Eric" last="Mick">Eric Mick</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Miranda, Ana" sort="Miranda, Ana" uniqKey="Miranda A" first="Ana" last="Miranda">Ana Miranda</name><affiliation wicri:level="1"><nlm:aff id="A22">Department of Developmental and Educational Psychology, University of Valencia, Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Developmental and Educational Psychology, University of Valencia, Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Muenke, Maximilian" sort="Muenke, Maximilian" uniqKey="Muenke M" first="Maximilian" last="Muenke">Maximilian Muenke</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A4">Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda</wicri:cityArea></affiliation></author><author><name sortKey="Mulas, Fernando" sort="Mulas, Fernando" uniqKey="Mulas F" first="Fernando" last="Mulas">Fernando Mulas</name><affiliation wicri:level="1"><nlm:aff id="A23">Department of Neuropaediatric, La Fe University Hospital, Faculty of Medicine, Valencia, Spain</nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea>Department of Neuropaediatric, La Fe University Hospital, Faculty of Medicine, Valencia</wicri:regionArea><wicri:noRegion>Valencia</wicri:noRegion></affiliation></author><author><name sortKey="Nelson, Stanley F" sort="Nelson, Stanley F" uniqKey="Nelson S" first="Stanley F." last="Nelson">Stanley F. Nelson</name><affiliation wicri:level="2"><nlm:aff id="A11">Department of Human Genetics, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Human Genetics, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Nguyen, T Trang" sort="Nguyen, T Trang" uniqKey="Nguyen T" first="T. Trang" last="Nguyen">T. Trang Nguyen</name><affiliation wicri:level="3"><nlm:aff id="A2">Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Oades, Robert D" sort="Oades, Robert D" uniqKey="Oades R" first="Robert D." last="Oades">Robert D. Oades</name><affiliation wicri:level="1"><nlm:aff id="A24">University Clinic for Child and Adolescent Psychiatry, Essen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>University Clinic for Child and Adolescent Psychiatry, Essen</wicri:regionArea><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion><wicri:noRegion>Essen</wicri:noRegion></affiliation></author><author><name sortKey="Ogdie, Matthew N" sort="Ogdie, Matthew N" uniqKey="Ogdie M" first="Matthew N." last="Ogdie">Matthew N. Ogdie</name><affiliation wicri:level="2"><nlm:aff id="A25">The Broad Institute, MIT, Cambridge, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>The Broad Institute, MIT, Cambridge</wicri:cityArea></affiliation></author><author><name sortKey="Palacio, Juan David" sort="Palacio, Juan David" uniqKey="Palacio J" first="Juan David" last="Palacio">Juan David Palacio</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Pineda, David" sort="Pineda, David" uniqKey="Pineda D" first="David" last="Pineda">David Pineda</name><affiliation wicri:level="1"><nlm:aff id="A20">Neurosciences Group, University of Antioquia, Medellín, Colombia</nlm:aff><country xml:lang="fr">Colombie</country><wicri:regionArea>Neurosciences Group, University of Antioquia, Medellín</wicri:regionArea><wicri:noRegion>Medellín</wicri:noRegion></affiliation></author><author><name sortKey="Reif, Andreas" sort="Reif, Andreas" uniqKey="Reif A" first="Andreas" last="Reif">Andreas Reif</name><affiliation wicri:level="1"><nlm:aff id="A18">ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Renner, Tobias J" sort="Renner, Tobias J" uniqKey="Renner T" first="Tobias J." last="Renner">Tobias J. Renner</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Roeyers, Herbert" sort="Roeyers, Herbert" uniqKey="Roeyers H" first="Herbert" last="Roeyers">Herbert Roeyers</name><affiliation wicri:level="4"><nlm:aff id="A27">Ghent University, Dunantlaan, Ghent, Belgium</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Ghent University, Dunantlaan, Ghent</wicri:regionArea><orgName type="university">Université de Gand</orgName><placeName><settlement type="city">Gand</settlement><region>Région flamande</region><region type="district" nuts="2">Province de Flandre-Orientale</region></placeName></affiliation></author><author><name sortKey="Romanos, Marcel" sort="Romanos, Marcel" uniqKey="Romanos M" first="Marcel" last="Romanos">Marcel Romanos</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name><affiliation wicri:level="1"><nlm:aff id="A28">Child and Adolescent Psychiatry, University of Gottingen, Gottingen, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Child and Adolescent Psychiatry, University of Gottingen, Gottingen</wicri:regionArea><wicri:noRegion>Gottingen</wicri:noRegion><wicri:noRegion>Gottingen</wicri:noRegion><wicri:noRegion>Gottingen</wicri:noRegion></affiliation></author><author><name sortKey="Sch Fer, Helmut" sort="Sch Fer, Helmut" uniqKey="Sch Fer H" first="Helmut" last="Sch Fer">Helmut Sch Fer</name><affiliation wicri:level="3"><nlm:aff id="A2">Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg</wicri:regionArea><placeName><region type="land" nuts="1">Hesse (Land)</region><region type="district" nuts="2">District de Giessen</region><settlement type="city">Marbourg</settlement></placeName></affiliation></author><author><name sortKey="Sergeant, Joseph" sort="Sergeant, Joseph" uniqKey="Sergeant J" first="Joseph" last="Sergeant">Joseph Sergeant</name><affiliation wicri:level="3"><nlm:aff id="A29">Vrije Universiteit, De Boelelaan, Amsterdam, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Vrije Universiteit, De Boelelaan, Amsterdam</wicri:regionArea><placeName><settlement type="city">Amsterdam</settlement><region nuts="2" type="province">Hollande-Septentrionale</region></placeName></affiliation></author><author><name sortKey="Sinke, Richard J" sort="Sinke, Richard J" uniqKey="Sinke R" first="Richard J." last="Sinke">Richard J. Sinke</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Medical Genetics, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Smalley, Susan L" sort="Smalley, Susan L" uniqKey="Smalley S" first="Susan L." last="Smalley">Susan L. Smalley</name><affiliation wicri:level="2"><nlm:aff id="A19">Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A30">Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</nlm:aff><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles</wicri:cityArea></affiliation></author><author><name sortKey="Sonuga Barke, Edmund" sort="Sonuga Barke, Edmund" uniqKey="Sonuga Barke E" first="Edmund" last="Sonuga-Barke">Edmund Sonuga-Barke</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A9">Child Study Center, New York University, New York, New York</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Child Study Center, New York University, New York</wicri:cityArea></affiliation><affiliation wicri:level="1"><nlm:aff id="A31">School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton</wicri:regionArea><wicri:noRegion>Southampton</wicri:noRegion></affiliation></author><author><name sortKey="Steinhausen, Hans Christoph" sort="Steinhausen, Hans Christoph" uniqKey="Steinhausen H" first="Hans-Christoph" last="Steinhausen">Hans-Christoph Steinhausen</name><affiliation wicri:level="4"><nlm:aff id="A32">Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland</nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University of Zurich, Zurich</wicri:regionArea><orgName type="university">Université de Zurich</orgName><placeName><settlement type="city">Zurich</settlement><region nuts="3" type="region">Canton de Zurich</region></placeName></affiliation></author><author><name sortKey="Van Der Meulen, Emma" sort="Van Der Meulen, Emma" uniqKey="Van Der Meulen E" first="Emma" last="Van Der Meulen">Emma Van Der Meulen</name><affiliation wicri:level="3"><nlm:aff id="A33">Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands</nlm:aff><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht</wicri:regionArea><placeName><settlement type="city">Utrecht</settlement><region nuts="2" type="province">Utrecht (province)</region></placeName></affiliation></author><author><name sortKey="Walitza, Susanne" sort="Walitza, Susanne" uniqKey="Walitza S" first="Susanne" last="Walitza">Susanne Walitza</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Warnke, Andreas" sort="Warnke, Andreas" uniqKey="Warnke A" first="Andreas" last="Warnke">Andreas Warnke</name><affiliation wicri:level="1"><nlm:aff id="A26">ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg</wicri:regionArea><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion><wicri:noRegion>Wuerzburg</wicri:noRegion></affiliation></author><author><name sortKey="Lewis, Cathryn M" sort="Lewis, Cathryn M" uniqKey="Lewis C" first="Cathryn M" last="Lewis">Cathryn M. Lewis</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="A12">Department of Medical and Molecular Genetics, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Medical and Molecular Genetics, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author><author><name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name><affiliation wicri:level="2"><nlm:aff id="A7">Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A34">Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">État de New York</region></placeName><wicri:cityArea>Department of Psychiatry, SUNY Upstate Medical University, Syracuse</wicri:cityArea></affiliation></author><author><name sortKey="Asherson, Philip" sort="Asherson, Philip" uniqKey="Asherson P" first="Philip" last="Asherson">Philip Asherson</name><affiliation wicri:level="3"><nlm:aff id="A1">Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London</wicri:regionArea><placeName><settlement type="city">Londres</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Grand Londres</region></placeName></affiliation></author></analytic><series><title level="j">American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics</title><idno type="ISSN">1552-4841</idno><idno type="eISSN">1552-485X</idno><imprint><date when="2008">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (<italic>P</italic><sub>SR</sub>=0.00034, <italic>P</italic><sub>OR</sub>=0.04) was identified on chromosome 16 between 64 and 83 Mb. In addition there are nine other genomic regions from the GSMA showing nominal or suggestive evidence of linkage. All these linkage results may be informative and focus the search for novel ADHD susceptibility genes.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101235742</journal-id><journal-id journal-id-type="pubmed-jr-id">32212</journal-id><journal-id journal-id-type="nlm-ta">Am J Med Genet B Neuropsychiatr Genet</journal-id><journal-title>American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics</journal-title><issn pub-type="ppub">1552-4841</issn><issn pub-type="epub">1552-485X</issn></journal-meta><article-meta><article-id pub-id-type="pmid">18988193</article-id><article-id pub-id-type="pmc">2890047</article-id><article-id pub-id-type="doi">10.1002/ajmg.b.30878</article-id><article-id pub-id-type="manuscript">NIHMS200277</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Zhou</surname><given-names>Kaixin</given-names></name><xref rid="A1" ref-type="aff">1</xref></contrib><contrib contrib-type="author"><name><surname>Dempfle</surname><given-names>Astrid</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Arcos-Burgos</surname><given-names>Mauricio</given-names></name><xref rid="A3" ref-type="aff">3</xref><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Bakker</surname><given-names>Steven C.</given-names></name><xref rid="A5" ref-type="aff">5</xref></contrib><contrib contrib-type="author"><name><surname>Banaschewski</surname><given-names>Tobias</given-names></name><xref rid="A6" ref-type="aff">6</xref></contrib><contrib contrib-type="author"><name><surname>Biederman</surname><given-names>Joseph</given-names></name><xref rid="A7" ref-type="aff">7</xref></contrib><contrib contrib-type="author"><name><surname>Buitelaar</surname><given-names>Jan</given-names></name><xref rid="A8" ref-type="aff">8</xref></contrib><contrib contrib-type="author"><name><surname>Castellanos</surname><given-names>F.Xavier</given-names></name><xref rid="A9" ref-type="aff">9</xref></contrib><contrib contrib-type="author"><name><surname>Doyle</surname><given-names>Alysa</given-names></name><xref rid="A7" ref-type="aff">7</xref></contrib><contrib contrib-type="author"><name><surname>Ebstein</surname><given-names>Richard P.</given-names></name><xref rid="A10" ref-type="aff">10</xref></contrib><contrib contrib-type="author"><name><surname>Ekholm</surname><given-names>Jenny</given-names></name><xref rid="A11" ref-type="aff">11</xref></contrib><contrib contrib-type="author"><name><surname>Forabosco</surname><given-names>Paola</given-names></name><xref rid="A12" ref-type="aff">12</xref><xref rid="A13" ref-type="aff">13</xref></contrib><contrib contrib-type="author"><name><surname>Franke</surname><given-names>Barbara</given-names></name><xref rid="A8" ref-type="aff">8</xref><xref rid="A14" ref-type="aff">14</xref></contrib><contrib contrib-type="author"><name><surname>Freitag</surname><given-names>Christine</given-names></name><xref rid="A15" ref-type="aff">15</xref></contrib><contrib contrib-type="author"><name><surname>Friedel</surname><given-names>Susann</given-names></name><xref rid="A16" ref-type="aff">16</xref></contrib><contrib contrib-type="author"><name><surname>Gill</surname><given-names>Michael</given-names></name><xref rid="A17" ref-type="aff">17</xref></contrib><contrib contrib-type="author"><name><surname>Hebebrand</surname><given-names>Johannes</given-names></name><xref rid="A16" ref-type="aff">16</xref></contrib><contrib contrib-type="author"><name><surname>Hinney</surname><given-names>Anke</given-names></name><xref rid="A16" ref-type="aff">16</xref></contrib><contrib contrib-type="author"><name><surname>Jacob</surname><given-names>Christian</given-names></name><xref rid="A18" ref-type="aff">18</xref></contrib><contrib contrib-type="author"><name><surname>Lesch</surname><given-names>Klaus Peter</given-names></name><xref rid="A18" ref-type="aff">18</xref></contrib><contrib contrib-type="author"><name><surname>Loo</surname><given-names>Sandra K.</given-names></name><xref rid="A19" ref-type="aff">19</xref></contrib><contrib contrib-type="author"><name><surname>Lopera</surname><given-names>Francisco</given-names></name><xref rid="A20" ref-type="aff">20</xref></contrib><contrib contrib-type="author"><name><surname>McCracken</surname><given-names>James T.</given-names></name><xref rid="A19" ref-type="aff">19</xref></contrib><contrib contrib-type="author"><name><surname>McGough</surname><given-names>James J.</given-names></name><xref rid="A19" ref-type="aff">19</xref></contrib><contrib contrib-type="author"><name><surname>Meyer</surname><given-names>Jobst</given-names></name><xref rid="A21" ref-type="aff">21</xref></contrib><contrib contrib-type="author"><name><surname>Mick</surname><given-names>Eric</given-names></name><xref rid="A7" ref-type="aff">7</xref></contrib><contrib contrib-type="author"><name><surname>Miranda</surname><given-names>Ana</given-names></name><xref rid="A22" ref-type="aff">22</xref></contrib><contrib contrib-type="author"><name><surname>Muenke</surname><given-names>Maximilian</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="A4" ref-type="aff">4</xref></contrib><contrib contrib-type="author"><name><surname>Mulas</surname><given-names>Fernando</given-names></name><xref rid="A23" ref-type="aff">23</xref></contrib><contrib contrib-type="author"><name><surname>Nelson</surname><given-names>Stanley F.</given-names></name><xref rid="A11" ref-type="aff">11</xref></contrib><contrib contrib-type="author"><name><surname>Nguyen</surname><given-names>T.Trang</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Oades</surname><given-names>Robert D.</given-names></name><xref rid="A24" ref-type="aff">24</xref></contrib><contrib contrib-type="author"><name><surname>Ogdie</surname><given-names>Matthew N.</given-names></name><xref rid="A25" ref-type="aff">25</xref></contrib><contrib contrib-type="author"><name><surname>Palacio</surname><given-names>Juan David</given-names></name><xref rid="A20" ref-type="aff">20</xref></contrib><contrib contrib-type="author"><name><surname>Pineda</surname><given-names>David</given-names></name><xref rid="A20" ref-type="aff">20</xref></contrib><contrib contrib-type="author"><name><surname>Reif</surname><given-names>Andreas</given-names></name><xref rid="A18" ref-type="aff">18</xref></contrib><contrib contrib-type="author"><name><surname>Renner</surname><given-names>Tobias J.</given-names></name><xref rid="A26" ref-type="aff">26</xref></contrib><contrib contrib-type="author"><name><surname>Roeyers</surname><given-names>Herbert</given-names></name><xref rid="A27" ref-type="aff">27</xref></contrib><contrib contrib-type="author"><name><surname>Romanos</surname><given-names>Marcel</given-names></name><xref rid="A26" ref-type="aff">26</xref></contrib><contrib contrib-type="author"><name><surname>Rothenberger</surname><given-names>Aribert</given-names></name><xref rid="A28" ref-type="aff">28</xref></contrib><contrib contrib-type="author"><name><surname>Schäfer</surname><given-names>Helmut</given-names></name><xref rid="A2" ref-type="aff">2</xref></contrib><contrib contrib-type="author"><name><surname>Sergeant</surname><given-names>Joseph</given-names></name><xref rid="A29" ref-type="aff">29</xref></contrib><contrib contrib-type="author"><name><surname>Sinke</surname><given-names>Richard J.</given-names></name><xref rid="A5" ref-type="aff">5</xref></contrib><contrib contrib-type="author"><name><surname>Smalley</surname><given-names>Susan L.</given-names></name><xref rid="A19" ref-type="aff">19</xref><xref rid="A30" ref-type="aff">30</xref></contrib><contrib contrib-type="author"><name><surname>Sonuga-Barke</surname><given-names>Edmund</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="A9" ref-type="aff">9</xref><xref rid="A31" ref-type="aff">31</xref></contrib><contrib contrib-type="author"><name><surname>Steinhausen</surname><given-names>Hans-Christoph</given-names></name><xref rid="A32" ref-type="aff">32</xref></contrib><contrib contrib-type="author"><name><surname>van der Meulen</surname><given-names>Emma</given-names></name><xref rid="A33" ref-type="aff">33</xref></contrib><contrib contrib-type="author"><name><surname>Walitza</surname><given-names>Susanne</given-names></name><xref rid="A26" ref-type="aff">26</xref></contrib><contrib contrib-type="author"><name><surname>Warnke</surname><given-names>Andreas</given-names></name><xref rid="A26" ref-type="aff">26</xref></contrib><contrib contrib-type="author"><name><surname>Lewis</surname><given-names>Cathryn M</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="A12" ref-type="aff">12</xref></contrib><contrib contrib-type="author"><name><surname>Faraone</surname><given-names>Stephen V.</given-names></name><xref rid="A7" ref-type="aff">7</xref><xref rid="A34" ref-type="aff">34</xref></contrib><contrib contrib-type="author"><name><surname>Asherson</surname><given-names>Philip</given-names></name><xref rid="A1" ref-type="aff">1</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib></contrib-group><aff id="A1"><label>1</label>Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK</aff><aff id="A2"><label>2</label>Institute of Medical Biometry and Epidemiology, Philipps-University Marburg, Marburg, Germany</aff><aff id="A3"><label>3</label>Department of Psychiatry and Behavioral Sciences, Leonard M. Miller School of Medicine, University of Miami, Miami, Florida</aff><aff id="A4"><label>4</label>Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland</aff><aff id="A5"><label>5</label>Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands</aff><aff id="A6"><label>6</label>Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany</aff><aff id="A7"><label>7</label>Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts</aff><aff id="A8"><label>8</label>Department of Psychiatry, Radboud University Nijmegen, Donders Centre for Neuroscience, Medical Centre, Nijmegen, The Netherlands</aff><aff id="A9"><label>9</label>Child Study Center, New York University, New York, New York</aff><aff id="A10"><label>10</label>Geha MHC, Petach-Tikva, Israel</aff><aff id="A11"><label>11</label>Department of Human Genetics, UCLA, Los Angeles, California</aff><aff id="A12"><label>12</label>Department of Medical and Molecular Genetics, King's College London, London, UK</aff><aff id="A13"><label>13</label>Istituto di Genetica delle Popolazioni—CNR, Alghero, Italy</aff><aff id="A14"><label>14</label>Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands</aff><aff id="A15"><label>15</label>Department of Child and Adolescent Psychiatry, Saarland University Hospital, Homburg, Germany</aff><aff id="A16"><label>16</label>Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany</aff><aff id="A17"><label>17</label>Department of Psychiatry, Trinity Centre for Health Sciences, St. James's Hospital, Dublin, Ireland</aff><aff id="A18"><label>18</label>ADHD Clinical Research Program, Department of Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</aff><aff id="A19"><label>19</label>Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</aff><aff id="A20"><label>20</label>Neurosciences Group, University of Antioquia, Medellín, Colombia</aff><aff id="A21"><label>21</label>Department of Neurobehavioral Genetics, University of Trier, Trier, Germany</aff><aff id="A22"><label>22</label>Department of Developmental and Educational Psychology, University of Valencia, Valencia, Spain</aff><aff id="A23"><label>23</label>Department of Neuropaediatric, La Fe University Hospital, Faculty of Medicine, Valencia, Spain</aff><aff id="A24"><label>24</label>University Clinic for Child and Adolescent Psychiatry, Essen, Germany</aff><aff id="A25"><label>25</label>The Broad Institute, MIT, Cambridge, Massachusetts</aff><aff id="A26"><label>26</label>ADHD Clinical Research Program, Department of Child and Adolescent Psychiatry and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany</aff><aff id="A27"><label>27</label>Ghent University, Dunantlaan, Ghent, Belgium</aff><aff id="A28"><label>28</label>Child and Adolescent Psychiatry, University of Gottingen, Gottingen, Germany</aff><aff id="A29"><label>29</label>Vrije Universiteit, De Boelelaan, Amsterdam, The Netherlands</aff><aff id="A30"><label>30</label>Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, UCLA, Los Angeles, California</aff><aff id="A31"><label>31</label>School of Psychology, Institute for Disorder on Impulse and Attention, University of Southampton, Highfield, Southampton, UK</aff><aff id="A32"><label>32</label>Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland</aff><aff id="A33"><label>33</label>Department of Child and Adolescent Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands</aff><aff id="A34"><label>34</label>Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York</aff><author-notes><corresp id="FN1"><label>*</label>Correspondence to: Dr. Philip Asherson, MRC Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London SE5 8AF, UK. <email>p.asherson@iop.kcl.ac.uk</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>10</day><month>5</month><year>2010</year></pub-date><pub-date pub-type="ppub"><day>5</day><month>12</month><year>2008</year></pub-date><pub-date pub-type="pmc-release"><day>23</day><month>6</month><year>2010</year></pub-date><volume>147B</volume><issue>8</issue><fpage>1392</fpage><lpage>1398</lpage><abstract><p id="P1">Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-wide linkage scans have been performed to map loci that increase the risk for ADHD. Although significant linkage signals were identified in some of the studies, there has been limited replications between the various independent datasets. The current study gathered the results from all seven of the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide significant linkage (<italic>P</italic><sub>SR</sub>=0.00034, <italic>P</italic><sub>OR</sub>=0.04) was identified on chromosome 16 between 64 and 83 Mb. In addition there are nine other genomic regions from the GSMA showing nominal or suggestive evidence of linkage. All these linkage results may be informative and focus the search for novel ADHD susceptibility genes.</p></abstract><kwd-group><kwd>ADHD</kwd><kwd>GSMA</kwd><kwd>linkage</kwd></kwd-group><contract-num rid="MH1">R01 MH062873-05
||MH</contract-num><contract-num rid="HD1">R01 HD037694-05
||HD</contract-num><contract-sponsor id="MH1">National Institute of Mental Health : NIMH</contract-sponsor><contract-sponsor id="HD1">National Institute of Child Health & Human Development : NICHD</contract-sponsor></article-meta></front></pmc><affiliations><list><country><li>Allemagne</li><li>Belgique</li><li>Colombie</li><li>Espagne</li><li>Irlande (pays)</li><li>Israël</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suisse</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Bade-Wurtemberg</li><li>Californie</li><li>Canton de Zurich</li><li>District de Giessen</li><li>District de Karlsruhe</li><li>Floride</li><li>Grand Londres</li><li>Gueldre</li><li>Hesse (Land)</li><li>Hollande-Septentrionale</li><li>Maryland</li><li>Massachusetts</li><li>Province de Flandre-Orientale</li><li>Rhénanie-Palatinat</li><li>Région flamande</li><li>Utrecht (province)</li><li>État de New York</li></region><settlement><li>Amsterdam</li><li>Gand</li><li>Londres</li><li>Mannheim</li><li>Marbourg</li><li>Nimègue</li><li>Trèves (Allemagne)</li><li>Utrecht</li><li>Zurich</li></settlement><orgName><li>Université de Gand</li><li>Université de Trèves</li><li>Université de Zurich</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Zhou, Kaixin" sort="Zhou, Kaixin" uniqKey="Zhou K" first="Kaixin" last="Zhou">Kaixin Zhou</name></region><name sortKey="Asherson, Philip" sort="Asherson, Philip" uniqKey="Asherson P" first="Philip" last="Asherson">Philip Asherson</name><name sortKey="Forabosco, Paola" sort="Forabosco, Paola" uniqKey="Forabosco P" first="Paola" last="Forabosco">Paola Forabosco</name><name sortKey="Lewis, Cathryn M" sort="Lewis, Cathryn M" uniqKey="Lewis C" first="Cathryn M" last="Lewis">Cathryn M. Lewis</name><name sortKey="Lewis, Cathryn M" sort="Lewis, Cathryn M" uniqKey="Lewis C" first="Cathryn M" last="Lewis">Cathryn M. Lewis</name><name sortKey="Muenke, Maximilian" sort="Muenke, Maximilian" uniqKey="Muenke M" first="Maximilian" last="Muenke">Maximilian Muenke</name><name sortKey="Sonuga Barke, Edmund" sort="Sonuga Barke, Edmund" uniqKey="Sonuga Barke E" first="Edmund" last="Sonuga-Barke">Edmund Sonuga-Barke</name><name sortKey="Sonuga Barke, Edmund" sort="Sonuga Barke, Edmund" uniqKey="Sonuga Barke E" first="Edmund" last="Sonuga-Barke">Edmund Sonuga-Barke</name></country><country name="Allemagne"><region name="Hesse (Land)"><name sortKey="Dempfle, Astrid" sort="Dempfle, Astrid" uniqKey="Dempfle A" first="Astrid" last="Dempfle">Astrid Dempfle</name></region><name sortKey="Banaschewski, Tobias" sort="Banaschewski, Tobias" uniqKey="Banaschewski T" first="Tobias" last="Banaschewski">Tobias Banaschewski</name><name sortKey="Freitag, Christine" sort="Freitag, Christine" uniqKey="Freitag C" first="Christine" last="Freitag">Christine Freitag</name><name sortKey="Friedel, Susann" sort="Friedel, Susann" uniqKey="Friedel S" first="Susann" last="Friedel">Susann Friedel</name><name sortKey="Hebebrand, Johannes" sort="Hebebrand, Johannes" uniqKey="Hebebrand J" first="Johannes" last="Hebebrand">Johannes Hebebrand</name><name sortKey="Hinney, Anke" sort="Hinney, Anke" uniqKey="Hinney A" first="Anke" last="Hinney">Anke Hinney</name><name sortKey="Jacob, Christian" sort="Jacob, Christian" uniqKey="Jacob C" first="Christian" last="Jacob">Christian Jacob</name><name sortKey="Lesch, Klaus Peter" sort="Lesch, Klaus Peter" uniqKey="Lesch K" first="Klaus Peter" last="Lesch">Klaus Peter Lesch</name><name sortKey="Meyer, Jobst" sort="Meyer, Jobst" uniqKey="Meyer J" first="Jobst" last="Meyer">Jobst Meyer</name><name sortKey="Nguyen, T Trang" sort="Nguyen, T Trang" uniqKey="Nguyen T" first="T. Trang" last="Nguyen">T. Trang Nguyen</name><name sortKey="Oades, Robert D" sort="Oades, Robert D" uniqKey="Oades R" first="Robert D." last="Oades">Robert D. Oades</name><name sortKey="Reif, Andreas" sort="Reif, Andreas" uniqKey="Reif A" first="Andreas" last="Reif">Andreas Reif</name><name sortKey="Renner, Tobias J" sort="Renner, Tobias J" uniqKey="Renner T" first="Tobias J." last="Renner">Tobias J. Renner</name><name sortKey="Romanos, Marcel" sort="Romanos, Marcel" uniqKey="Romanos M" first="Marcel" last="Romanos">Marcel Romanos</name><name sortKey="Rothenberger, Aribert" sort="Rothenberger, Aribert" uniqKey="Rothenberger A" first="Aribert" last="Rothenberger">Aribert Rothenberger</name><name sortKey="Sch Fer, Helmut" sort="Sch Fer, Helmut" uniqKey="Sch Fer H" first="Helmut" last="Sch Fer">Helmut Sch Fer</name><name sortKey="Walitza, Susanne" sort="Walitza, Susanne" uniqKey="Walitza S" first="Susanne" last="Walitza">Susanne Walitza</name><name sortKey="Warnke, Andreas" sort="Warnke, Andreas" uniqKey="Warnke A" first="Andreas" last="Warnke">Andreas Warnke</name></country><country name="États-Unis"><region name="Floride"><name sortKey="Arcos Burgos, Mauricio" sort="Arcos Burgos, Mauricio" uniqKey="Arcos Burgos M" first="Mauricio" last="Arcos-Burgos">Mauricio Arcos-Burgos</name></region><name sortKey="Arcos Burgos, Mauricio" sort="Arcos Burgos, Mauricio" uniqKey="Arcos Burgos M" first="Mauricio" last="Arcos-Burgos">Mauricio Arcos-Burgos</name><name sortKey="Biederman, Joseph" sort="Biederman, Joseph" uniqKey="Biederman J" first="Joseph" last="Biederman">Joseph Biederman</name><name sortKey="Castellanos, F Xavier" sort="Castellanos, F Xavier" uniqKey="Castellanos F" first="F. Xavier" last="Castellanos">F. Xavier Castellanos</name><name sortKey="Doyle, Alysa" sort="Doyle, Alysa" uniqKey="Doyle A" first="Alysa" last="Doyle">Alysa Doyle</name><name sortKey="Ekholm, Jenny" sort="Ekholm, Jenny" uniqKey="Ekholm J" first="Jenny" last="Ekholm">Jenny Ekholm</name><name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name><name sortKey="Faraone, Stephen V" sort="Faraone, Stephen V" uniqKey="Faraone S" first="Stephen V." last="Faraone">Stephen V. Faraone</name><name sortKey="Loo, Sandra K" sort="Loo, Sandra K" uniqKey="Loo S" first="Sandra K." last="Loo">Sandra K. Loo</name><name sortKey="Mccracken, James T" sort="Mccracken, James T" uniqKey="Mccracken J" first="James T." last="Mccracken">James T. Mccracken</name><name sortKey="Mcgough, James J" sort="Mcgough, James J" uniqKey="Mcgough J" first="James J." last="Mcgough">James J. Mcgough</name><name sortKey="Mick, Eric" sort="Mick, Eric" uniqKey="Mick E" first="Eric" last="Mick">Eric Mick</name><name sortKey="Muenke, Maximilian" sort="Muenke, Maximilian" uniqKey="Muenke M" first="Maximilian" last="Muenke">Maximilian Muenke</name><name sortKey="Nelson, Stanley F" sort="Nelson, Stanley F" uniqKey="Nelson S" first="Stanley F." last="Nelson">Stanley F. Nelson</name><name sortKey="Ogdie, Matthew N" sort="Ogdie, Matthew N" uniqKey="Ogdie M" first="Matthew N." last="Ogdie">Matthew N. Ogdie</name><name sortKey="Smalley, Susan L" sort="Smalley, Susan L" uniqKey="Smalley S" first="Susan L." last="Smalley">Susan L. Smalley</name><name sortKey="Smalley, Susan L" sort="Smalley, Susan L" uniqKey="Smalley S" first="Susan L." last="Smalley">Susan L. Smalley</name><name sortKey="Sonuga Barke, Edmund" sort="Sonuga Barke, Edmund" uniqKey="Sonuga Barke E" first="Edmund" last="Sonuga-Barke">Edmund Sonuga-Barke</name></country><country name="Pays-Bas"><region name="Utrecht (province)"><name sortKey="Bakker, Steven C" sort="Bakker, Steven C" uniqKey="Bakker S" first="Steven C." last="Bakker">Steven C. Bakker</name></region><name sortKey="Buitelaar, Jan" sort="Buitelaar, Jan" uniqKey="Buitelaar J" first="Jan" last="Buitelaar">Jan Buitelaar</name><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><name sortKey="Sergeant, Joseph" sort="Sergeant, Joseph" uniqKey="Sergeant J" first="Joseph" last="Sergeant">Joseph Sergeant</name><name sortKey="Sinke, Richard J" sort="Sinke, Richard J" uniqKey="Sinke R" first="Richard J." last="Sinke">Richard J. Sinke</name><name sortKey="Van Der Meulen, Emma" sort="Van Der Meulen, Emma" uniqKey="Van Der Meulen E" first="Emma" last="Van Der Meulen">Emma Van Der Meulen</name></country><country name="Israël"><noRegion><name sortKey="Ebstein, Richard P" sort="Ebstein, Richard P" uniqKey="Ebstein R" first="Richard P." last="Ebstein">Richard P. Ebstein</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Forabosco, Paola" sort="Forabosco, Paola" uniqKey="Forabosco P" first="Paola" last="Forabosco">Paola Forabosco</name></noRegion></country><country name="Irlande (pays)"><noRegion><name sortKey="Gill, Michael" sort="Gill, Michael" uniqKey="Gill M" first="Michael" last="Gill">Michael Gill</name></noRegion></country><country name="Colombie"><noRegion><name sortKey="Lopera, Francisco" sort="Lopera, Francisco" uniqKey="Lopera F" first="Francisco" last="Lopera">Francisco Lopera</name></noRegion><name sortKey="Palacio, Juan David" sort="Palacio, Juan David" uniqKey="Palacio J" first="Juan David" last="Palacio">Juan David Palacio</name><name sortKey="Pineda, David" sort="Pineda, David" uniqKey="Pineda D" first="David" last="Pineda">David Pineda</name></country><country name="Espagne"><noRegion><name sortKey="Miranda, Ana" sort="Miranda, Ana" uniqKey="Miranda A" first="Ana" last="Miranda">Ana Miranda</name></noRegion><name sortKey="Mulas, Fernando" sort="Mulas, Fernando" uniqKey="Mulas F" first="Fernando" last="Mulas">Fernando Mulas</name></country><country name="Belgique"><region name="Région flamande"><name sortKey="Roeyers, Herbert" sort="Roeyers, Herbert" uniqKey="Roeyers H" first="Herbert" last="Roeyers">Herbert Roeyers</name></region></country><country name="Suisse"><region name="Canton de Zurich"><name sortKey="Steinhausen, Hans Christoph" sort="Steinhausen, Hans Christoph" uniqKey="Steinhausen H" first="Hans-Christoph" last="Steinhausen">Hans-Christoph Steinhausen</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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