Hypercalcemia after transplant nephrectomy in a hemodialysis patient: a case report
Identifieur interne : 001405 ( Main/Merge ); précédent : 001404; suivant : 001406Hypercalcemia after transplant nephrectomy in a hemodialysis patient: a case report
Auteurs : Ivo Quack [Allemagne] ; Magdalena Woznowski [Allemagne] ; Gisela Schieren [Allemagne] ; Stefan M. Weiner [Allemagne] ; Guido Winnekendonk [Allemagne] ; Faruk Tokmak [Allemagne] ; Lars C. Rump [Allemagne] ; Dirk Rattensperger [Allemagne]Source :
- Journal of Medical Case Reports [ 1752-1947 ] ; 2007.
Abstract
Hypercalcemia is a complication often seen in chronic hemodialysis patients. A rare cause of this condition is sarcoidosis. Its highly variable clinical presentation is challenging. Especially in patients suffering chronic kidney graft failure the nonspecific constitutional symptoms of sarcoidosis like fever, weight loss, arthralgia and fatigue may be easily misleading.
A 51 year old male developed hypercalcemia, arthralgia and B-symptoms after explantation of his kidney graft because of suspected acute rejection. The removed kidney showed vasculopathy and tubulointerstitial nephritis, which had not been overt in the biopsy taken half a year earlier. Despite explantation and withdrawal of the immunosuppression the patient's general condition deteriorated progressively. A rapid rise in serum calcium finally provoked us to check for sarcoidosis. CT scans of the lungs, broncho-alveolar-lavage and further lab tests confirmed the diagnosis.
This case demonstrates that withdrawal of immunosuppressive drugs sometimes unmasks sarcoidosis. It should be considered as differential diagnosis even in hemodialysis patients, in whom other reasons for hypercalcemia are much more common.
Url:
DOI: 10.1186/1752-1947-1-164
PubMed: 18053167
PubMed Central: 2241629
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000080
- to stream Pmc, to step Curation: 000080
- to stream Pmc, to step Checkpoint: 000177
- to stream Ncbi, to step Merge: 000284
- to stream Ncbi, to step Curation: 000284
- to stream Ncbi, to step Checkpoint: 000284
Links to Exploration step
PMC:2241629Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Hypercalcemia after transplant nephrectomy in a hemodialysis patient: a case report</title><author><name sortKey="Quack, Ivo" sort="Quack, Ivo" uniqKey="Quack I" first="Ivo" last="Quack">Ivo Quack</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Woznowski, Magdalena" sort="Woznowski, Magdalena" uniqKey="Woznowski M" first="Magdalena" last="Woznowski">Magdalena Woznowski</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Schieren, Gisela" sort="Schieren, Gisela" uniqKey="Schieren G" first="Gisela" last="Schieren">Gisela Schieren</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Weiner, Stefan M" sort="Weiner, Stefan M" uniqKey="Weiner S" first="Stefan M" last="Weiner">Stefan M. Weiner</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I5">current address : Internal Medicine 2, Nephrology, Krankenhaus Bamherzige Brueder, Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Internal Medicine 2, Nephrology, Krankenhaus Bamherzige Brueder, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion></affiliation></author><author><name sortKey="Winnekendonk, Guido" sort="Winnekendonk, Guido" uniqKey="Winnekendonk G" first="Guido" last="Winnekendonk">Guido Winnekendonk</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Radiology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation></author><author><name sortKey="Tokmak, Faruk" sort="Tokmak, Faruk" uniqKey="Tokmak F" first="Faruk" last="Tokmak">Faruk Tokmak</name><affiliation wicri:level="1"><nlm:aff id="I3">Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum</wicri:regionArea><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Rump, Lars C" sort="Rump, Lars C" uniqKey="Rump L" first="Lars C" last="Rump">Lars C. Rump</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Rattensperger, Dirk" sort="Rattensperger, Dirk" uniqKey="Rattensperger D" first="Dirk" last="Rattensperger">Dirk Rattensperger</name><affiliation wicri:level="1"><nlm:aff id="I3">Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum</wicri:regionArea><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">18053167</idno><idno type="pmc">2241629</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241629</idno><idno type="RBID">PMC:2241629</idno><idno type="doi">10.1186/1752-1947-1-164</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">000080</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000080</idno><idno type="wicri:Area/Pmc/Curation">000080</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000080</idno><idno type="wicri:Area/Pmc/Checkpoint">000177</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000177</idno><idno type="wicri:Area/Ncbi/Merge">000284</idno><idno type="wicri:Area/Ncbi/Curation">000284</idno><idno type="wicri:Area/Ncbi/Checkpoint">000284</idno><idno type="wicri:Area/Main/Merge">001405</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Hypercalcemia after transplant nephrectomy in a hemodialysis patient: a case report</title><author><name sortKey="Quack, Ivo" sort="Quack, Ivo" uniqKey="Quack I" first="Ivo" last="Quack">Ivo Quack</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Woznowski, Magdalena" sort="Woznowski, Magdalena" uniqKey="Woznowski M" first="Magdalena" last="Woznowski">Magdalena Woznowski</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Schieren, Gisela" sort="Schieren, Gisela" uniqKey="Schieren G" first="Gisela" last="Schieren">Gisela Schieren</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Weiner, Stefan M" sort="Weiner, Stefan M" uniqKey="Weiner S" first="Stefan M" last="Weiner">Stefan M. Weiner</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I5">current address : Internal Medicine 2, Nephrology, Krankenhaus Bamherzige Brueder, Trier, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Internal Medicine 2, Nephrology, Krankenhaus Bamherzige Brueder, Trier</wicri:regionArea><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion><wicri:noRegion>Trier</wicri:noRegion></affiliation></author><author><name sortKey="Winnekendonk, Guido" sort="Winnekendonk, Guido" uniqKey="Winnekendonk G" first="Guido" last="Winnekendonk">Guido Winnekendonk</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Radiology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Radiology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation></author><author><name sortKey="Tokmak, Faruk" sort="Tokmak, Faruk" uniqKey="Tokmak F" first="Faruk" last="Tokmak">Faruk Tokmak</name><affiliation wicri:level="1"><nlm:aff id="I3">Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum</wicri:regionArea><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion></affiliation></author><author><name sortKey="Rump, Lars C" sort="Rump, Lars C" uniqKey="Rump L" first="Lars C" last="Rump">Lars C. Rump</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Nephrology, Marienhospital Herne, Ruhr-University Bochum, Hoelkeskampring 40, 44625 Herne</wicri:regionArea><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion><wicri:noRegion>44625 Herne</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">current address : Renal department, Heinrich-Heine University, Duesseldorf, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>current address : Renal department, Heinrich-Heine University, Duesseldorf</wicri:regionArea><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion><wicri:noRegion>Duesseldorf</wicri:noRegion></affiliation></author><author><name sortKey="Rattensperger, Dirk" sort="Rattensperger, Dirk" uniqKey="Rattensperger D" first="Dirk" last="Rattensperger">Dirk Rattensperger</name><affiliation wicri:level="1"><nlm:aff id="I3">Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum, Germany</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Kuratorium für Heimdialyse und Nierentransplantation, Cruismannstrasse 37, 44807 Bochum</wicri:regionArea><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion><wicri:noRegion>44807 Bochum</wicri:noRegion></affiliation></author></analytic><series><title level="j">Journal of Medical Case Reports</title><idno type="eISSN">1752-1947</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Hypercalcemia is a complication often seen in chronic hemodialysis patients. A rare cause of this condition is sarcoidosis. Its highly variable clinical presentation is challenging. Especially in patients suffering chronic kidney graft failure the nonspecific constitutional symptoms of sarcoidosis like fever, weight loss, arthralgia and fatigue may be easily misleading.</p></sec><sec><title>Case presentation</title><p>A 51 year old male developed hypercalcemia, arthralgia and B-symptoms after explantation of his kidney graft because of suspected acute rejection. The removed kidney showed vasculopathy and tubulointerstitial nephritis, which had not been overt in the biopsy taken half a year earlier. Despite explantation and withdrawal of the immunosuppression the patient's general condition deteriorated progressively. A rapid rise in serum calcium finally provoked us to check for sarcoidosis. CT scans of the lungs, broncho-alveolar-lavage and further lab tests confirmed the diagnosis.</p></sec><sec><title>Conclusion</title><p>This case demonstrates that withdrawal of immunosuppressive drugs sometimes unmasks sarcoidosis. It should be considered as differential diagnosis even in hemodialysis patients, in whom other reasons for hypercalcemia are much more common.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001405 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 001405 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Rhénanie
|area= UnivTrevesV1
|flux= Main
|étape= Merge
|type= RBID
|clé= PMC:2241629
|texte= Hypercalcemia after transplant nephrectomy in a hemodialysis patient: a case report
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:18053167" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a UnivTrevesV1
| This area was generated with Dilib version V0.6.31. |  |