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Association between brain‐derived neurotrophic factor V66M and treatment responses to escitalopram in patients with major depressive disorder

Identifieur interne : 000802 ( Main/Exploration ); précédent : 000801; suivant : 000803

Association between brain‐derived neurotrophic factor V66M and treatment responses to escitalopram in patients with major depressive disorder

Auteurs : Hun Soo Chang [Corée du Sud] ; Hwa-Young Lee [Corée du Sud] ; Byung-Joo Ham [Corée du Sud] ; Yong Chon Park [Corée du Sud] ; Sang-Woo Hahn [Corée du Sud] ; Yoo-Jung Jeong [Corée du Sud] ; Bohye Kim [Corée du Sud] ; Min-Soo Lee [Corée du Sud]

Source :

RBID : ISTEX:7B825E43DB430BE8729B3832C34CC2FECE0B7E91

Abstract

Brain‐derived neurotrophic factor (BDNF) is a candidate molecule for influencing the clinical response to antidepressant treatment. Among polymorphisms on the BDNF gene, V66M (rs6265) has been reported to be associated with response to antidepressant treatment. The aims of this study were to determine the relationship between the V66M polymorphism and the response to escitalopram in patients with major depressive disorder (MDD).

Url:
DOI: 10.1111/j.1758-5872.2012.00219.x


Affiliations:


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<div type="abstract">Brain‐derived neurotrophic factor (BDNF) is a candidate molecule for influencing the clinical response to antidepressant treatment. Among polymorphisms on the BDNF gene, V66M (rs6265) has been reported to be associated with response to antidepressant treatment. The aims of this study were to determine the relationship between the V66M polymorphism and the response to escitalopram in patients with major depressive disorder (MDD).</div>
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