Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala
Identifieur interne : 001B51 ( Istex/Corpus ); précédent : 001B50; suivant : 001B52Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala
Auteurs : Dominik R. Bach ; Hartmut Schchinger ; John G. Neuhoff ; Fabrizio Esposito ; Francesco Di Salle ; Christoph Lehmann ; Marcus Herdener ; Klaus Scheffler ; Erich SeifritzSource :
- Cerebral Cortex [ 1047-3211 ] ; 2007-05-08.
Abstract
Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.
Url:
DOI: 10.1093/cercor/bhm040
Links to Exploration step
ISTEX:5FAE585157553B8200899ADC4EACE8D012DF02EDLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title><author><name sortKey="Bach, Dominik R" sort="Bach, Dominik R" uniqKey="Bach D" first="Dominik R." last="Bach">Dominik R. Bach</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: bach@puk.unibe.ch</mods:affiliation></affiliation></author><author><name sortKey="Schchinger, Hartmut" sort="Schchinger, Hartmut" uniqKey="Schchinger H" first="Hartmut" last="Schchinger">Hartmut Schchinger</name><affiliation><mods:affiliation>Department of Clinical Physiology, FB IPsychobiology, University of Trier, 54290 Trier, Germany</mods:affiliation></affiliation></author><author><name sortKey="Neuhoff, John G" sort="Neuhoff, John G" uniqKey="Neuhoff J" first="John G." last="Neuhoff">John G. Neuhoff</name><affiliation><mods:affiliation>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</mods:affiliation></affiliation></author><author><name sortKey="Esposito, Fabrizio" sort="Esposito, Fabrizio" uniqKey="Esposito F" first="Fabrizio" last="Esposito">Fabrizio Esposito</name><affiliation><mods:affiliation>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</mods:affiliation></affiliation></author><author><name sortKey="Salle, Francesco Di" sort="Salle, Francesco Di" uniqKey="Salle F" first="Francesco Di" last="Salle">Francesco Di Salle</name><affiliation><mods:affiliation>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</mods:affiliation></affiliation></author><author><name sortKey="Lehmann, Christoph" sort="Lehmann, Christoph" uniqKey="Lehmann C" first="Christoph" last="Lehmann">Christoph Lehmann</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Herdener, Marcus" sort="Herdener, Marcus" uniqKey="Herdener M" first="Marcus" last="Herdener">Marcus Herdener</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Scheffler, Klaus" sort="Scheffler, Klaus" uniqKey="Scheffler K" first="Klaus" last="Scheffler">Klaus Scheffler</name><affiliation><mods:affiliation>Department of Radiology, University of Basel, 4031 Basel, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Seifritz, Erich" sort="Seifritz, Erich" uniqKey="Seifritz E" first="Erich" last="Seifritz">Erich Seifritz</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5FAE585157553B8200899ADC4EACE8D012DF02ED</idno><date when="2008" year="2008">2008</date><idno type="doi">10.1093/cercor/bhm040</idno><idno type="url">https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001B51</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001B51</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a">Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title><author><name sortKey="Bach, Dominik R" sort="Bach, Dominik R" uniqKey="Bach D" first="Dominik R." last="Bach">Dominik R. Bach</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: bach@puk.unibe.ch</mods:affiliation></affiliation></author><author><name sortKey="Schchinger, Hartmut" sort="Schchinger, Hartmut" uniqKey="Schchinger H" first="Hartmut" last="Schchinger">Hartmut Schchinger</name><affiliation><mods:affiliation>Department of Clinical Physiology, FB IPsychobiology, University of Trier, 54290 Trier, Germany</mods:affiliation></affiliation></author><author><name sortKey="Neuhoff, John G" sort="Neuhoff, John G" uniqKey="Neuhoff J" first="John G." last="Neuhoff">John G. Neuhoff</name><affiliation><mods:affiliation>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</mods:affiliation></affiliation></author><author><name sortKey="Esposito, Fabrizio" sort="Esposito, Fabrizio" uniqKey="Esposito F" first="Fabrizio" last="Esposito">Fabrizio Esposito</name><affiliation><mods:affiliation>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</mods:affiliation></affiliation></author><author><name sortKey="Salle, Francesco Di" sort="Salle, Francesco Di" uniqKey="Salle F" first="Francesco Di" last="Salle">Francesco Di Salle</name><affiliation><mods:affiliation>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</mods:affiliation></affiliation></author><author><name sortKey="Lehmann, Christoph" sort="Lehmann, Christoph" uniqKey="Lehmann C" first="Christoph" last="Lehmann">Christoph Lehmann</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Herdener, Marcus" sort="Herdener, Marcus" uniqKey="Herdener M" first="Marcus" last="Herdener">Marcus Herdener</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Scheffler, Klaus" sort="Scheffler, Klaus" uniqKey="Scheffler K" first="Klaus" last="Scheffler">Klaus Scheffler</name><affiliation><mods:affiliation>Department of Radiology, University of Basel, 4031 Basel, Switzerland</mods:affiliation></affiliation></author><author><name sortKey="Seifritz, Erich" sort="Seifritz, Erich" uniqKey="Seifritz E" first="Erich" last="Seifritz">Erich Seifritz</name><affiliation><mods:affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Cerebral Cortex</title><idno type="ISSN">1047-3211</idno><idno type="eISSN">1460-2199</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2007-05-08">2007-05-08</date><biblScope unit="volume">18</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="145">145</biblScope><biblScope unit="page" to="150">150</biblScope></imprint><idno type="ISSN">1047-3211</idno></series><idno type="istex">5FAE585157553B8200899ADC4EACE8D012DF02ED</idno><idno type="DOI">10.1093/cercor/bhm040</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1047-3211</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract">Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.</div></front></TEI><istex><corpusName>oup</corpusName><author><json:item><name>Dominik R. Bach</name><affiliations><json:string>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</json:string><json:string>E-mail: bach@puk.unibe.ch</json:string></affiliations></json:item><json:item><name>Hartmut Schchinger</name><affiliations><json:string>Department of Clinical Physiology, FB IPsychobiology, University of Trier, 54290 Trier, Germany</json:string></affiliations></json:item><json:item><name>John G. Neuhoff</name><affiliations><json:string>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</json:string></affiliations></json:item><json:item><name>Fabrizio Esposito</name><affiliations><json:string>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</json:string></affiliations></json:item><json:item><name>Francesco Di Salle</name><affiliations><json:string>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</json:string></affiliations></json:item><json:item><name>Christoph Lehmann</name><affiliations><json:string>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</json:string></affiliations></json:item><json:item><name>Marcus Herdener</name><affiliations><json:string>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</json:string></affiliations></json:item><json:item><name>Klaus Scheffler</name><affiliations><json:string>Department of Radiology, University of Basel, 4031 Basel, Switzerland</json:string></affiliations></json:item><json:item><name>Erich Seifritz</name><affiliations><json:string>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</json:string><json:string>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</json:string></affiliations></json:item></author><subject><json:item><value>Articles</value></json:item><json:item><value>amygdala</value></json:item><json:item><value>auditory looming</value></json:item><json:item><value>fMRI</value></json:item><json:item><value>orienting reflex</value></json:item><json:item><value>phasic alertness</value></json:item><json:item><value>skin conductance response</value></json:item></subject><language><json:string>unknown</json:string></language><originalGenre><json:string>research-article</json:string></originalGenre><abstract>Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.</abstract><qualityIndicators><score>8.764</score><pdfVersion>1.3</pdfVersion><pdfPageSize>594 x 783 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>7</keywordCount><abstractCharCount>1095</abstractCharCount><pdfWordCount>5060</pdfWordCount><pdfCharCount>33311</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>147</abstractWordCount></qualityIndicators><title>Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title><refBibs><json:item><author><json:item><name>A Amedi</name></json:item><json:item><name>K Von Kriegstein</name></json:item><json:item><name>Nm Van Atteveldt</name></json:item><json:item><name>Ms Beauchamp</name></json:item><json:item><name>Mj Naumer</name></json:item></author><host><volume>166</volume><pages><last>571</last><first>559</first></pages><author></author><title>Exp Brain Res</title><publicationDate>2005</publicationDate></host><title>Functional imaging of human crossmodal identification and object recognition</title><publicationDate>2005</publicationDate></json:item><json:item><author><json:item><name>Kc Anderson</name></json:item><json:item><name>Rm Siegel</name></json:item></author><host><volume>19</volume><pages><last>2692</last><first>2681</first></pages><author></author><title>J Neurosci</title><publicationDate>1999</publicationDate></host><title>Optic flow selectivity in the anterior superior temporal polysensory area, STPa, of the behaving monkey</title><publicationDate>1999</publicationDate></json:item><json:item><author><json:item><name>W Ball</name></json:item><json:item><name>E Tronick</name></json:item></author><host><volume>171</volume><pages><last>820</last><first>818</first></pages><author></author><title>Science</title><publicationDate>1971</publicationDate></host><title>Infant responses to impending collision: optical and real</title><publicationDate>1971</publicationDate></json:item><json:item><author><json:item><name>Ne Barraclough</name></json:item><json:item><name>D Xiao</name></json:item><json:item><name>Ci Baker</name></json:item><json:item><name>Mw Oram</name></json:item><json:item><name>Di Perrett</name></json:item></author><host><volume>17</volume><pages><last>391</last><first>377</first></pages><issue>1</issue><author></author><title>J Cogn Neurosci. Cerebral Cortex</title><publicationDate>2005-01</publicationDate></host><title>Integration of visual and auditory information by superior temporal sulcus neurons responsive to the sight of actions</title><publicationDate>2005-01</publicationDate></json:item><json:item><author><json:item><name>Rj Barry</name></json:item></author><host><pages><last>195</last><first>131</first></pages><author></author><title>Advances in psychophysiology</title><publicationDate>1987</publicationDate></host><title>Preliminary processes in orienting response elicitation</title><publicationDate>1987</publicationDate></json:item><json:item><author><json:item><name>Ms Beauchamp</name></json:item></author><host><volume>15</volume><pages><last>153</last><first>145</first></pages><author></author><title>Curr Opin Neurobiol</title><publicationDate>2005</publicationDate></host><title>See me, hear me, touch me: multisensory integration in lateral occipital-temporal cortex</title><publicationDate>2005</publicationDate></json:item><json:item><author><json:item><name>Hc Breiter</name></json:item><json:item><name>Nl Etcoff</name></json:item><json:item><name>Pj Whalen</name></json:item><json:item><name>Wa Kennedy</name></json:item><json:item><name>Sl Rauch</name></json:item><json:item><name>Rl Buckner</name></json:item><json:item><name>Mm Strauss</name></json:item><json:item><name>Se Hyman</name></json:item><json:item><name>Br Rosen</name></json:item></author><host><volume>17</volume><pages><last>887</last><first>875</first></pages><author></author><title>Neuron</title><publicationDate>1996</publicationDate></host><title>Response and habituation of the human amygdala during visual processing of facial expression</title><publicationDate>1996</publicationDate></json:item><json:item><author><json:item><name>F Bremmer</name></json:item><json:item><name>A Schlack</name></json:item><json:item><name>Nj Shah</name></json:item><json:item><name>O Zafiris</name></json:item><json:item><name>M Kubischik</name></json:item><json:item><name>K Hoffmann</name></json:item><json:item><name>K Zilles</name></json:item><json:item><name>Gr Fink</name></json:item></author><host><volume>29</volume><pages><last>296</last><first>287</first></pages><author></author><title>Neuron</title><publicationDate>2001</publicationDate></host><title>Polymodal motion processing in posterior parietal and premotor cortex: a human fMRI study strongly implies equivalencies between humans and monkeys</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>R Cowie</name></json:item><json:item><name>E Douglas-Cowie</name></json:item><json:item><name>N Tsapatsoulis</name></json:item><json:item><name>G Votsis</name></json:item><json:item><name>S Kollias</name></json:item><json:item><name>W Fellenz</name></json:item><json:item><name>Jg Taylor</name></json:item></author><host><volume>18</volume><pages><last>79</last><first>33</first></pages><author></author><title>IEEE Signal Process Mag</title><publicationDate>2001</publicationDate></host><title>Emotion recognition in human-computer interaction</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>M Davis</name></json:item><json:item><name>Pj Whalen</name></json:item></author><host><volume>6</volume><pages><last>34</last><first>13</first></pages><author></author><title>Mol Psychiatry</title><publicationDate>2001</publicationDate></host><title>The amygdala: vigilance and emotion</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>J Downar</name></json:item><json:item><name>Ap Crawley</name></json:item><json:item><name>Dj Mikulis</name></json:item><json:item><name>Kd Davis</name></json:item></author><host><volume>3</volume><pages><last>283</last><first>277</first></pages><author></author><title>Nat Neurosci</title><publicationDate>2000</publicationDate></host><title>A multimodal cortical network for the detection of changes in the sensory environment</title><publicationDate>2000</publicationDate></json:item><json:item><author><json:item><name>A Etkin</name></json:item><json:item><name>Kc Klemenhagen</name></json:item><json:item><name>Jt Dudman</name></json:item><json:item><name>Mt Rogan</name></json:item><json:item><name>R Hen</name></json:item><json:item><name>Er Kandel</name></json:item><json:item><name>J Hirsch</name></json:item></author><host><volume>44</volume><pages><last>1055</last><first>1043</first></pages><author></author><title>Neuron</title><publicationDate>2004</publicationDate></host><title>Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces</title><publicationDate>2004</publicationDate></json:item><json:item><author><json:item><name>Sd Forman</name></json:item><json:item><name>Jd Cohen</name></json:item><json:item><name>M Fitzgerald</name></json:item><json:item><name>Wf Eddy</name></json:item><json:item><name>Ma Mintun</name></json:item><json:item><name>Dc Noll</name></json:item></author><host><volume>33</volume><pages><last>647</last><first>636</first></pages><author></author><title>Magn Reson Med</title><publicationDate>1995</publicationDate></host><title>Improved assessment of significant activation in functional magnetic resonance imaging (fMRI): use of a cluster-size threshold</title><publicationDate>1995</publicationDate></json:item><json:item><author><json:item><name>Aa Ghazanfar</name></json:item><json:item><name>Jg Neuhoff</name></json:item><json:item><name>Nk Logothetis</name></json:item></author><host><volume>99</volume><pages><last>15757</last><first>15755</first></pages><author></author><title>Proc Natl Acad Sci</title><publicationDate>2002</publicationDate></host><title>Auditory looming perception in rhesus monkeys</title><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>Ms Gordon</name></json:item><json:item><name>Ld Rosenblum</name></json:item></author><host><volume>67</volume><pages><last>594</last><first>580</first></pages><author></author><title>Percept Psychophys</title><publicationDate>2005</publicationDate></host><title>Effects of intrastimulus modality change on audiovisual time-to-arrival judgments</title><publicationDate>2005</publicationDate></json:item><json:item><author><json:item><name>N Gosselin</name></json:item><json:item><name>I Peretz</name></json:item><json:item><name>M Noulhiane</name></json:item><json:item><name>D Hasboun</name></json:item><json:item><name>C Beckett</name></json:item><json:item><name>M Baulac</name></json:item><json:item><name>S Samson</name></json:item></author><host><volume>128</volume><pages><last>640</last><first>628</first></pages><author></author><title>Brain</title><publicationDate>2005</publicationDate></host><title>Impaired recognition of scary music following unilateral temporal lobe excision</title><publicationDate>2005</publicationDate></json:item><json:item><author><json:item><name>Ms Graziano</name></json:item><json:item><name>Df Cooke</name></json:item></author><host><volume>44</volume><pages><last>2635</last><first>2621</first></pages><author></author><title>Neuropsychologia</title><publicationDate>2006</publicationDate></host><title>Parieto-frontal interactions, personal space, and defensive behavior</title><publicationDate>2006</publicationDate></json:item><json:item><author><json:item><name>Td Griffiths</name></json:item><json:item><name>Jd Warren</name></json:item></author><host><volume>25</volume><pages><last>353</last><first>348</first></pages><author></author><title>Trends Neurosci</title><publicationDate>2002</publicationDate></host><title>The planum temporale as a computational hub</title><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>R Guski</name></json:item></author><host><volume>43</volume><pages><last>197</last><first>189</first></pages><author></author><title>Ecol Psychol</title><publicationDate>1992</publicationDate></host><title>Acoustic tau: an easy analogue to visual tau?</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Da Hall</name></json:item><json:item><name>Dr Moore</name></json:item></author><host><volume>13</volume><pages><last>93</last><first>91</first></pages><author></author><title>Curr Biol</title><publicationDate>2003</publicationDate></host><title>Auditory neuroscience: the salience of looming sounds</title><publicationDate>2003</publicationDate></json:item><json:item><author><json:item><name>R Henson</name></json:item><json:item><name>T Shallice</name></json:item><json:item><name>R Dolan</name></json:item></author><host><volume>287</volume><pages><last>1272</last><first>1269</first></pages><author></author><title>Science</title><publicationDate>2000</publicationDate></host><title>Neuroimaging evidence for dissociable forms of repetition priming</title><publicationDate>2000</publicationDate></json:item><json:item><author><json:item><name>Rn Henson</name></json:item><json:item><name>Cj Price</name></json:item><json:item><name>Md Rugg</name></json:item><json:item><name>R Turner</name></json:item><json:item><name>Kj Friston</name></json:item></author><host><volume>15</volume><pages><last>97</last><first>83</first></pages><author></author><title>Neuroimage</title><publicationDate>2002</publicationDate></host><title>Detecting latency differences in event-related BOLD responses: application to words versus nonwords and initial versus repeated face presentations</title><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>M Herdener</name></json:item><json:item><name>F Esposito</name></json:item><json:item><name>Di Salle</name></json:item><json:item><name>F Lehmann</name></json:item><json:item><name>C Bach</name></json:item><json:item><name>Dr Scheffler</name></json:item><json:item><name>K Seifritz</name></json:item><json:item><name>E </name></json:item></author><host><volume>36</volume><pages><last>201</last><first>194</first></pages><author></author><title>Neuroimage</title><publicationDate>2007</publicationDate></host><title>BOLD correlates of edge detection in human auditory cortex</title><publicationDate>2007</publicationDate></json:item><json:item><author><json:item><name>Pa Lewis</name></json:item><json:item><name>Hd Critchley</name></json:item><json:item><name>P Rotshtein</name></json:item><json:item><name>Rj Dolan</name></json:item></author><host><volume>17</volume><pages><last>748</last><first>742</first></pages><author></author><title>Cereb Cortex</title><publicationDate>2006</publicationDate></host><title>Neural correlates of processing valence and arousal in affective words</title><publicationDate>2006</publicationDate></json:item><json:item><author><json:item><name>T Lu</name></json:item><json:item><name>L Liang</name></json:item><json:item><name>X Wang</name></json:item></author><host><volume>4</volume><pages><last>1138</last><first>1131</first></pages><author></author><title>Nat Neurosci</title><publicationDate>2001</publicationDate></host><title>Temporal and rate representations of timevarying signals in the auditory cortex of awake primates</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>Jx Maier</name></json:item><json:item><name>Jg Neuhoff</name></json:item><json:item><name>Nk Logothetis</name></json:item><json:item><name>Aa Ghazanfar</name></json:item></author><host><volume>43</volume><pages><last>181</last><first>177</first></pages><author></author><title>Neuron</title><publicationDate>2004</publicationDate></host><title>Multisensory integration of looming signals by rhesus monkeys</title><publicationDate>2004</publicationDate></json:item><json:item><author><json:item><name>Js Morris</name></json:item><json:item><name>Sk Scott</name></json:item><json:item><name>Rj Dolan</name></json:item></author><host><volume>37</volume><pages><last>1163</last><first>1155</first></pages><author></author><title>Neuropsychologia</title><publicationDate>1999</publicationDate></host><title>Saying it with feeling: neural responses to emotional vocalizations</title><publicationDate>1999</publicationDate></json:item><json:item><author><json:item><name>Jg Neuhoff</name></json:item></author><host><volume>395</volume><pages><last>124</last><first>123</first></pages><author></author><title>Nature</title><publicationDate>1998</publicationDate></host><title>Perceptual bias for rising tones</title><publicationDate>1998</publicationDate></json:item><json:item><author><json:item><name>Jg Neuhoff</name></json:item></author><host><volume>132</volume><pages><last>110</last><first>87</first></pages><author></author><title>Ecol Psychol</title><publicationDate>2001</publicationDate></host><title>An adaptive bias in the perception of looming auditory motion</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>F Pavani</name></json:item><json:item><name>E Macaluso</name></json:item><json:item><name>Jd Warren</name></json:item><json:item><name>J Driver</name></json:item><json:item><name>Td Griffiths</name></json:item></author><host><volume>12</volume><pages><last>1590</last><first>1584</first></pages><author></author><title>Curr Biol</title><publicationDate>2002</publicationDate></host><title>A common cortical substrate activated by horizontal and vertical sound movement in the human brain</title><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>Ml Phillips</name></json:item><json:item><name>Aw Young</name></json:item><json:item><name>Sk Scott</name></json:item><json:item><name>Aj Calder</name></json:item><json:item><name>C Andrew</name></json:item><json:item><name>V Giampietro</name></json:item><json:item><name>Cr Williams</name></json:item><json:item><name>Et Bullmore</name></json:item><json:item><name>M Brammer</name></json:item><json:item><name>Ja Gray</name></json:item></author><host><volume>265</volume><pages><last>1817</last><first>1809</first></pages><author></author><title>Proc R Soc Lond B Biol Sci</title><publicationDate>1998</publicationDate></host><title>Neural responses to facial and vocal expressions of fear and disgust</title><publicationDate>1998</publicationDate></json:item><json:item><author><json:item><name>Mi Posner</name></json:item></author><host><volume>32</volume><pages><last>25</last><first>3</first></pages><author></author><title>Q J Exp Psychol</title><publicationDate>1980</publicationDate></host><title>Orienting of attention</title><publicationDate>1980</publicationDate></json:item><json:item><author><json:item><name>Kl Roberts</name></json:item><json:item><name>Aq Summerfield</name></json:item><json:item><name>Da Hall</name></json:item></author><host><volume>12</volume><pages><last>492</last><first>485</first></pages><author></author><title>J Int Neuropsychol Soc</title><publicationDate>2006</publicationDate></host><title>Presentation modality influences behavioral measures of alerting, orienting, and executive control</title><publicationDate>2006</publicationDate></json:item><json:item><author><json:item><name>Jb Rosen</name></json:item><json:item><name>Mp Donley</name></json:item></author><host><volume>73</volume><pages><last>60</last><first>49</first></pages><author></author><title>Biol Psychol</title><publicationDate>2006</publicationDate></host><title>Animal studies of amygdala function in fear and uncertainty: relevance to human research</title><publicationDate>2006</publicationDate></json:item><json:item><author><json:item><name>Ld Rosenblum</name></json:item><json:item><name>C Carello</name></json:item><json:item><name>Re Pastore</name></json:item></author><host><volume>16</volume><pages><last>186</last><first>175</first></pages><author></author><title>Perception</title><publicationDate>1987</publicationDate></host><title>Relative effectiveness of three stimulus variables for locating a moving sound source</title><publicationDate>1987</publicationDate></json:item><json:item><author><json:item><name>D Sander</name></json:item><json:item><name>J Grafman</name></json:item><json:item><name>T Zalla</name></json:item></author><host><volume>14</volume><pages><last>316</last><first>303</first></pages><author></author><title>Rev Neurosci</title><publicationDate>2003</publicationDate></host><title>The human amygdala: an evolved system for relevance detection</title><publicationDate>2003</publicationDate></json:item><json:item><author><json:item><name>D Sander</name></json:item><json:item><name>D Grandjean</name></json:item><json:item><name>G Pourtois</name></json:item><json:item><name>S Schwartz</name></json:item><json:item><name>Ml Seghier</name></json:item><json:item><name>Kr Scherer</name></json:item><json:item><name>P Vuilleumier</name></json:item></author><host><volume>28</volume><pages><last>858</last><first>848</first></pages><author></author><title>Neuroimage</title><publicationDate>2005</publicationDate></host><title>Emotion and attention interactions in social cognition: brain regions involved in processing anger prosody</title><publicationDate>2005</publicationDate></json:item><json:item><author><json:item><name>K Sander</name></json:item><json:item><name>H Scheich</name></json:item></author><host><volume>12</volume><pages><last>198</last><first>181</first></pages><author></author><title>Brain Res Cogn Brain Res</title><publicationDate>2001</publicationDate></host><title>Auditory perception of laughing and crying activates human amygdala regardless of attentional state</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>W Schiff</name></json:item><json:item><name>R Oldak</name></json:item></author><host><volume>16</volume><pages><last>316</last><first>303</first></pages><author></author><title>J Exp Psychol Hum Percept Perform</title><publicationDate>1990</publicationDate></host><title>Accuracy of judging time to arrival: effects of modality, trajectory, and gender</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>E Seifritz</name></json:item><json:item><name>F Esposito</name></json:item><json:item><name>Jg Neuhoff</name></json:item><json:item><name>A Luthi</name></json:item><json:item><name>H Mustovic</name></json:item><json:item><name>G Dammann</name></json:item><json:item><name>U Von Bardeleben</name></json:item><json:item><name>Ew Radue</name></json:item><json:item><name>S Cirillo</name></json:item><json:item><name>G Tedeschi</name></json:item></author><host><volume>54</volume><pages><last>1375</last><first>1367</first></pages><author></author><title>Biol Psychiatry</title><publicationDate>2003</publicationDate></host><title>Differential sex-independent amygdala response to infant crying and laughing in parents versus nonparents</title><publicationDate>2003</publicationDate></json:item><json:item><author><json:item><name>E Seifritz</name></json:item><json:item><name>Jg Neuhoff</name></json:item><json:item><name>D Bilecen</name></json:item><json:item><name>K Scheffler</name></json:item><json:item><name>H Mustovic</name></json:item><json:item><name>H Schachinger</name></json:item><json:item><name>R Elefante</name></json:item><json:item><name>Di Salle</name></json:item><json:item><name>F </name></json:item></author><host><pages><last>2151</last><first>2147</first></pages><author></author><title>Neural processing of auditory looming in the human brain</title><publicationDate>2002</publicationDate></host><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>Da Siddle</name></json:item></author><host><volume>28</volume><pages><last>259</last><first>245</first></pages><author></author><title>Psychophysiology</title><publicationDate>1991</publicationDate></host><title>Orienting, habituation, and resource allocation: an associative analysis</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>En Solokov</name></json:item></author><host><volume>25</volume><pages><last>580</last><first>545</first></pages><author></author><title>Annu Rev Physiol</title><publicationDate>1963</publicationDate></host><title>Higher nervous functions; the orienting reflex</title><publicationDate>1963</publicationDate></json:item><json:item><author><json:item><name>W Sturm</name></json:item><json:item><name>K Willmes</name></json:item></author><host><volume>14</volume><pages><last>84</last><first>76</first></pages><author></author><title>Neuroimage</title><publicationDate>2001</publicationDate></host><title>On the functional neuroanatomy of intrinsic and phasic alertness</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>Cm Thiel</name></json:item><json:item><name>K Zilles</name></json:item><json:item><name>Gr Fink</name></json:item></author><host><volume>21</volume><pages><last>328</last><first>318</first></pages><author></author><title>Neuroimage</title><publicationDate>2004</publicationDate></host><title>Cerebral correlates of alerting, orienting and reorienting of visuospatial attention: an event-related fMRI study</title><publicationDate>2004</publicationDate></json:item><json:item><author><json:item><name>Jd Warren</name></json:item><json:item><name>Ba Zielinski</name></json:item><json:item><name>Gg Green</name></json:item><json:item><name>Jp Rauschecker</name></json:item><json:item><name>Td Griffiths</name></json:item></author><host><volume>34</volume><pages><last>148</last><first>139</first></pages><author></author><title>Neuron</title><publicationDate>2002</publicationDate></host><title>Perception of sound-source motion by the human brain</title><publicationDate>2002</publicationDate></json:item><json:item><author><json:item><name>Pj Whalen</name></json:item></author><host><volume>7</volume><pages><last>188</last><first>177</first></pages><author></author><title>Curr Dir Psychol Sci</title><publicationDate>1998</publicationDate></host><title>Fear, vigilance and ambiguity: initial neuroimaging studies of the human amygdala</title><publicationDate>1998</publicationDate></json:item><json:item><author><json:item><name>Lm Williams</name></json:item><json:item><name>Ml Phillips</name></json:item><json:item><name>Mj Brammer</name></json:item><json:item><name>D Skerrett</name></json:item><json:item><name>J Lagopoulos</name></json:item><json:item><name>C Rennie</name></json:item><json:item><name>H Bahramali</name></json:item><json:item><name>G Olivieri</name></json:item><json:item><name>As David</name></json:item><json:item><name>A Peduto</name></json:item></author><host><volume>14</volume><pages><last>1079</last><first>1070</first></pages><author></author><title>Neuroimage</title><publicationDate>2001</publicationDate></host><title>Arousal dissociates amygdala and hippocampal fear responses: evidence from simultaneous fMRI and skin conductance recording</title><publicationDate>2001</publicationDate></json:item><json:item><author><json:item><name>Kj Worsley</name></json:item><json:item><name>Kj Friston</name></json:item></author><host><volume>2</volume><pages><last>181</last><first>173</first></pages><author></author><title>Neuroimage</title><publicationDate>1995</publicationDate></host><title>Analysis of fMRI time-series revisited— again</title><publicationDate>1995</publicationDate></json:item><json:item><author><json:item><name>Dh Zald</name></json:item></author><host><volume>41</volume><pages><last>123</last><first>88</first></pages><author></author><title>Brain Res Rev</title><publicationDate>2003</publicationDate></host><title>The human amygdala and the emotional evaluation of sensory stimuli</title><publicationDate>2003</publicationDate></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>18</volume><publisherId><json:string>cercor</json:string></publisherId><pages><last>150</last><first>145</first></pages><issn><json:string>1047-3211</json:string></issn><issue>1</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1460-2199</json:string></eissn><title>Cerebral Cortex</title></host><categories><wos><json:string>science</json:string><json:string>neurosciences</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>psychology & cognitive sciences</json:string><json:string>experimental psychology</json:string></scienceMetrix></categories><publicationDate>2007</publicationDate><copyrightDate>2008</copyrightDate><doi><json:string>10.1093/cercor/bhm040</json:string></doi><id>5FAE585157553B8200899ADC4EACE8D012DF02ED</id><score>0.636912</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Oxford University Press</publisher><availability><p>The Author 2007. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org</p></availability><date>2007-05-08</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title><author xml:id="author-1" corresp="yes"><persName><forename type="first">Dominik R.</forename><surname>Bach</surname></persName><email>bach@puk.unibe.ch</email><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation></author><author xml:id="author-2"><persName><forename type="first">Hartmut</forename><surname>Schchinger</surname></persName><affiliation>Department of Clinical Physiology, FB IPsychobiology, University of Trier, 54290 Trier, Germany</affiliation></author><author xml:id="author-3"><persName><forename type="first">John G.</forename><surname>Neuhoff</surname></persName><affiliation>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</affiliation></author><author xml:id="author-4"><persName><forename type="first">Fabrizio</forename><surname>Esposito</surname></persName><affiliation>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</affiliation></author><author xml:id="author-5"><persName><forename type="first">Francesco Di</forename><surname>Salle</surname></persName><affiliation>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</affiliation></author><author xml:id="author-6"><persName><forename type="first">Christoph</forename><surname>Lehmann</surname></persName><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation></author><author xml:id="author-7"><persName><forename type="first">Marcus</forename><surname>Herdener</surname></persName><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation></author><author xml:id="author-8"><persName><forename type="first">Klaus</forename><surname>Scheffler</surname></persName><affiliation>Department of Radiology, University of Basel, 4031 Basel, Switzerland</affiliation></author><author xml:id="author-9"><persName><forename type="first">Erich</forename><surname>Seifritz</surname></persName><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation><affiliation>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</affiliation></author></analytic><monogr><title level="j">Cerebral Cortex</title><idno type="pISSN">1047-3211</idno><idno type="eISSN">1460-2199</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="2007-05-08"></date><biblScope unit="volume">18</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="145">145</biblScope><biblScope unit="page" to="150">150</biblScope></imprint></monogr><idno type="istex">5FAE585157553B8200899ADC4EACE8D012DF02ED</idno><idno type="DOI">10.1093/cercor/bhm040</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2007-05-08</date></creation><abstract><p>Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.</p></abstract><textClass><keywords scheme="keyword"><list><item><term>Articles</term></item></list></keywords></textClass><textClass><keywords scheme="keyword"><list><head>keywords</head><item><term>amygdala</term></item><item><term>auditory looming</term></item><item><term>fMRI</term></item><item><term>orienting reflex</term></item><item><term>phasic alertness</term></item><item><term>skin conductance response</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2007-05-08">Created</change><change when="2007-05-08">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-12-22">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus oup" wicri:toSee="no header"><istex:docType PUBLIC="-//NLM//DTD Journal Publishing DTD v2.3 20070202//EN" URI="journalpublishing.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article"><front><journal-meta><journal-id journal-id-type="hwp">cercor</journal-id><journal-id journal-id-type="publisher-id">cercor</journal-id><journal-title>Cerebral Cortex</journal-title><issn pub-type="epub">1460-2199</issn><issn pub-type="ppub">1047-3211</issn><publisher><publisher-name>Oxford University Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1093/cercor/bhm040</article-id><article-categories><subj-group><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Bach</surname><given-names>Dominik R.</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Schächinger</surname><given-names>Hartmut</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Neuhoff</surname><given-names>John G.</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Esposito</surname><given-names>Fabrizio</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Salle</surname><given-names>Francesco Di</given-names></name><xref ref-type="aff" rid="aff5">5</xref></contrib><contrib contrib-type="author"><name><surname>Lehmann</surname><given-names>Christoph</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Herdener</surname><given-names>Marcus</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Scheffler</surname><given-names>Klaus</given-names></name><xref ref-type="aff" rid="aff6">6</xref></contrib><contrib contrib-type="author"><name><surname>Seifritz</surname><given-names>Erich</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff7">7</xref></contrib></contrib-group><aff id="aff1"><label>1</label>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</aff><aff id="aff2"><label>2</label>Department of Clinical Physiology, FB I—Psychobiology, University of Trier, 54290 Trier, Germany</aff><aff id="aff3"><label>3</label>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</aff><aff id="aff4"><label>4</label>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</aff><aff id="aff5"><label>5</label>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</aff><aff id="aff6"><label>6</label>Department of Radiology, University of Basel, 4031 Basel, Switzerland</aff><aff id="aff7"><label>7</label>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</aff><author-notes><corresp>Address correspondence to Dominik R. Bach, Universitäre Psychiatrische Dienste Bern, Bolligenstrasse 111, 3000 Bern 60, Switzerland. Email: <email>bach@puk.unibe.ch</email>.</corresp></author-notes><pub-date pub-type="epub-ppub"><month>1</month><year>2008</year></pub-date><pub-date pub-type="epub"><day>8</day><month>5</month><year>2007</year></pub-date><volume>18</volume><issue>1</issue><fpage>145</fpage><lpage>150</lpage><permissions><copyright-statement>© The Author 2007. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org</copyright-statement><copyright-year>2008</copyright-year></permissions><abstract><p>Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.</p></abstract><kwd-group><kwd>amygdala</kwd><kwd>auditory looming</kwd><kwd>fMRI</kwd><kwd>orienting reflex</kwd><kwd>phasic alertness</kwd><kwd>skin conductance response</kwd></kwd-group></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Dominik R.</namePart><namePart type="family">Bach</namePart><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation><affiliation>E-mail: bach@puk.unibe.ch</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hartmut</namePart><namePart type="family">Schchinger</namePart><affiliation>Department of Clinical Physiology, FB IPsychobiology, University of Trier, 54290 Trier, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">John G.</namePart><namePart type="family">Neuhoff</namePart><affiliation>Department of Psychology, The College of Wooster, Wooster, OH 44691, USA</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Fabrizio</namePart><namePart type="family">Esposito</namePart><affiliation>Department of Neurological Sciences, University of Naples Federico II, 80127 Naples, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Francesco Di</namePart><namePart type="family">Salle</namePart><affiliation>Department of Neuroscience, University of Pisa, 56127 Pisa, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Christoph</namePart><namePart type="family">Lehmann</namePart><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Marcus</namePart><namePart type="family">Herdener</namePart><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Klaus</namePart><namePart type="family">Scheffler</namePart><affiliation>Department of Radiology, University of Basel, 4031 Basel, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Erich</namePart><namePart type="family">Seifritz</namePart><affiliation>University Hospital of Psychiatry, University of Bern, 3000 Bern, Switzerland</affiliation><affiliation>Department of Psychiatry, University of Basel, 4025 Basel, Switzerland</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><subject><topic>Articles</topic></subject><originInfo><publisher>Oxford University Press</publisher><dateIssued encoding="w3cdtf">2007-05-08</dateIssued><dateCreated encoding="w3cdtf">2007-05-08</dateCreated><copyrightDate encoding="w3cdtf">2008</copyrightDate></originInfo><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>Human subjects overestimate the change of rising intensity sounds compared with falling intensity sounds. Rising sound intensity has therefore been proposed to be an intrinsic warning cue. In order to test this hypothesis, we presented rising, falling, and constant intensity sounds to healthy humans and gathered psychophysiological and behavioral responses. Brain activity was measured using event-related functional magnetic resonance imaging. We found that rising compared with falling sound intensity facilitates autonomic orienting reflex and phasic alertness to auditory targets. Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane. Our results indicate that rising sound intensity is an elementary warning cue eliciting adaptive responses by recruiting attentional and physiological resources. Regions involved in cross-modal integration were activated by rising sound intensity, while the right-hemisphere phasic alertness network could not be supported by this study.</abstract><subject><genre>keywords</genre><topic>amygdala</topic><topic>auditory looming</topic><topic>fMRI</topic><topic>orienting reflex</topic><topic>phasic alertness</topic><topic>skin conductance response</topic></subject><relatedItem type="host"><titleInfo><title>Cerebral Cortex</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">1047-3211</identifier><identifier type="eISSN">1460-2199</identifier><identifier type="PublisherID">cercor</identifier><identifier type="PublisherID-hwp">cercor</identifier><part><date>2007</date><detail type="volume"><caption>vol.</caption><number>18</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>145</start><end>150</end></extent></part></relatedItem><identifier type="istex">5FAE585157553B8200899ADC4EACE8D012DF02ED</identifier><identifier type="DOI">10.1093/cercor/bhm040</identifier><accessCondition type="use and reproduction" contentType="copyright">The Author 2007. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org</accessCondition><recordInfo><recordContentSource>OUP</recordContentSource></recordInfo></mods></metadata><covers><json:item><extension>html</extension><original>true</original><mimetype>text/html</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/covers/html</uri></json:item><json:item><extension>tiff</extension><original>true</original><mimetype>image/tiff</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/covers/tiff</uri></json:item></covers><annexes><json:item><extension>jpeg</extension><original>true</original><mimetype>image/jpeg</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/annexes/jpeg</uri></json:item><json:item><extension>gif</extension><original>true</original><mimetype>image/gif</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/annexes/gif</uri></json:item><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/5FAE585157553B8200899ADC4EACE8D012DF02ED/annexes/pdf</uri></json:item></annexes><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B51 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001B51 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Rhénanie
|area= UnivTrevesV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:5FAE585157553B8200899ADC4EACE8D012DF02ED
|texte= Rising Sound Intensity: An Intrinsic Warning Cue Activating the Amygdala
}}
| This area was generated with Dilib version V0.6.31. |  |