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Carotid artery stenting: Do procedural complications relate to the side intervened upon?

Identifieur interne : 001804 ( Istex/Corpus ); précédent : 001803; suivant : 001805

Carotid artery stenting: Do procedural complications relate to the side intervened upon?

Auteurs : Ralf Zahn ; Thomas Ischinger ; Matthias Hochadel ; Bernd Mark ; Uwe Zeymer ; Wolfgang Schmalz ; Alexander Schramm ; Karl Eugen Hauptmann ; Hubert Seggewi ; Ilse Janicke ; Harald Mudra ; Jochen Senges

Source :

RBID : ISTEX:B02FEE693FC770FDD7B3ACD8544CF427D7DDC16F

English descriptors

Abstract

Objectives: To determine the influence of the side intervened upon on outcomes during carotid artery stenting (CAS). Background: Anatomic and technical aspects may influence the results of CAS. The value of the side intervened upon has not been analyzed yet. Methods: We analyzed data from the Carotid Artery Stent (CAS) – Registry. Results: A total of 3,165 CAS procedures, 1,613 (51%) at the left and 1,552 (49%) at the right carotid artery were included. There was a higher proportion of patients treated for symptomatic stenoses when CAS was performed at the left carotid artery (50.1% versus 45.8%, P = 0.016) and more patients already had prior carotid endarterectomy (8.5% versus 5.8%, P = 0.003). Interventions at the left side took 3 min longer than interventions at the right side (46.6 ± 24.3 versus 43.8 ± 23.6, P = 0.003). In patients treated at the left carotid artery amaurosis fugax (0.7% versus 0.1%, P = 0.005), ipsilateral stroke (3.1% versus 1.8%, P = 0.017), and the primary endpoint of in‐hospital death or stroke (4.1% versus 2.3%, P = 0.005) occurred significantly more often. Even after adjusting for confounding parameters, CAS procedures performed at the left carotid arteries remained an independent predictor of death or stroke (OR = 1.77, 95% CI: 1.15–2.72, P = 0.009). Conclusions: In current clinical practice, CAS is performed frequently at the right carotid artery as at the left carotid artery. CAS interventions have a higher in‐hospital complication rate if performed at the left carotid artery. Technical improvements might help to overcome this situation. © 2009 Wiley‐Liss, Inc.

Url:
DOI: 10.1002/ccd.22050

Links to Exploration step

ISTEX:B02FEE693FC770FDD7B3ACD8544CF427D7DDC16F

Le document en format XML

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<div type="abstract" xml:lang="en">Objectives: To determine the influence of the side intervened upon on outcomes during carotid artery stenting (CAS). Background: Anatomic and technical aspects may influence the results of CAS. The value of the side intervened upon has not been analyzed yet. Methods: We analyzed data from the Carotid Artery Stent (CAS) – Registry. Results: A total of 3,165 CAS procedures, 1,613 (51%) at the left and 1,552 (49%) at the right carotid artery were included. There was a higher proportion of patients treated for symptomatic stenoses when CAS was performed at the left carotid artery (50.1% versus 45.8%, P = 0.016) and more patients already had prior carotid endarterectomy (8.5% versus 5.8%, P = 0.003). Interventions at the left side took 3 min longer than interventions at the right side (46.6 ± 24.3 versus 43.8 ± 23.6, P = 0.003). In patients treated at the left carotid artery amaurosis fugax (0.7% versus 0.1%, P = 0.005), ipsilateral stroke (3.1% versus 1.8%, P = 0.017), and the primary endpoint of in‐hospital death or stroke (4.1% versus 2.3%, P = 0.005) occurred significantly more often. Even after adjusting for confounding parameters, CAS procedures performed at the left carotid arteries remained an independent predictor of death or stroke (OR = 1.77, 95% CI: 1.15–2.72, P = 0.009). Conclusions: In current clinical practice, CAS is performed frequently at the right carotid artery as at the left carotid artery. CAS interventions have a higher in‐hospital complication rate if performed at the left carotid artery. Technical improvements might help to overcome this situation. © 2009 Wiley‐Liss, Inc.</div>
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<p>Objectives: To determine the influence of the side intervened upon on outcomes during carotid artery stenting (CAS). Background: Anatomic and technical aspects may influence the results of CAS. The value of the side intervened upon has not been analyzed yet. Methods: We analyzed data from the Carotid Artery Stent (CAS) – Registry. Results: A total of 3,165 CAS procedures, 1,613 (51%) at the left and 1,552 (49%) at the right carotid artery were included. There was a higher proportion of patients treated for symptomatic stenoses when CAS was performed at the left carotid artery (50.1% versus 45.8%, P = 0.016) and more patients already had prior carotid endarterectomy (8.5% versus 5.8%, P = 0.003). Interventions at the left side took 3 min longer than interventions at the right side (46.6 ± 24.3 versus 43.8 ± 23.6, P = 0.003). In patients treated at the left carotid artery amaurosis fugax (0.7% versus 0.1%, P = 0.005), ipsilateral stroke (3.1% versus 1.8%, P = 0.017), and the primary endpoint of in‐hospital death or stroke (4.1% versus 2.3%, P = 0.005) occurred significantly more often. Even after adjusting for confounding parameters, CAS procedures performed at the left carotid arteries remained an independent predictor of death or stroke (OR = 1.77, 95% CI: 1.15–2.72, P = 0.009). Conclusions: In current clinical practice, CAS is performed frequently at the right carotid artery as at the left carotid artery. CAS interventions have a higher in‐hospital complication rate if performed at the left carotid artery. Technical improvements might help to overcome this situation. © 2009 Wiley‐Liss, Inc.</p>
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: A total of 3,165 CAS procedures, 1,613 (51%) at the left and 1,552 (49%) at the right carotid artery were included. There was a higher proportion of patients treated for symptomatic stenoses when CAS was performed at the left carotid artery (50.1% versus 45.8%,
<i>P</i>
= 0.016) and more patients already had prior carotid endarterectomy (8.5% versus 5.8%,
<i>P</i>
= 0.003). Interventions at the left side took 3 min longer than interventions at the right side (46.6 ± 24.3 versus 43.8 ± 23.6,
<i>P</i>
= 0.003). In patients treated at the left carotid artery amaurosis fugax (0.7% versus 0.1%,
<i>P</i>
= 0.005), ipsilateral stroke (3.1% versus 1.8%,
<i>P</i>
= 0.017), and the primary endpoint of in‐hospital death or stroke (4.1% versus 2.3%,
<i>P</i>
= 0.005) occurred significantly more often. Even after adjusting for confounding parameters, CAS procedures performed at the left carotid arteries remained an independent predictor of death or stroke (OR = 1.77, 95% CI: 1.15–2.72,
<i>P</i>
= 0.009).
<span cssStyle="text-decoration:underline">Conclusions</span>
: In current clinical practice, CAS is performed frequently at the right carotid artery as at the left carotid artery. CAS interventions have a higher in‐hospital complication rate if performed at the left carotid artery. Technical improvements might help to overcome this situation. © 2009 Wiley‐Liss, Inc.</p>
</abstract>
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<noteGroup>
<note xml:id="fn6">
<p>Conflict of interest: Drs. Zahn, Ischinger, and Mudra have received travel expenses or payment for speaking at meetings from one or more companies which produces or distributes embolic protection devices or carotid stents.</p>
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<titleInfo lang="en">
<title>Carotid artery stenting: Do procedural complications relate to the side intervened upon?</title>
<subTitle>Results From the Carotid Artery Stent (CAS)—Registry of the Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte (ALKK)</subTitle>
</titleInfo>
<titleInfo type="abbreviated" lang="en">
<title>CAS: Influence of the Side Intervened Upon</title>
</titleInfo>
<titleInfo type="alternative" contentType="CDATA" lang="en">
<title>Carotid artery stenting: Do procedural complications relate to the side intervened upon?</title>
</titleInfo>
<name type="personal">
<namePart type="given">Ralf</namePart>
<namePart type="family">Zahn</namePart>
<namePart type="termsOfAddress">MD, FESC, FAHA</namePart>
<affiliation>Herzzentrum Ludwigshafen, Kardiologie, Ludwigshafen, Germany</affiliation>
<affiliation>Herzzentrum Ludwigshafen, Kardiologie, Bremserstraße 79, D – 67063 Ludwigshafen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Thomas</namePart>
<namePart type="family">Ischinger</namePart>
<namePart type="termsOfAddress">MD, FESC, FACC</namePart>
<affiliation>Städtisches Klinikum, Kardiologie, München‐Bogenhausen</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Matthias</namePart>
<namePart type="family">Hochadel</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Institut für Herzinfarktforschung, Ludwigshafen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Bernd</namePart>
<namePart type="family">Mark</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Herzzentrum Ludwigshafen, Kardiologie, Ludwigshafen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Uwe</namePart>
<namePart type="family">Zeymer</namePart>
<namePart type="termsOfAddress">MD, FESC</namePart>
<affiliation>Herzzentrum Ludwigshafen, Kardiologie, Ludwigshafen, Germany</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Wolfgang</namePart>
<namePart type="family">Schmalz</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Stadtkrankenhaus, Kardiologie, Worms</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Alexander</namePart>
<namePart type="family">Schramm</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Marienhospital, Kardiologie, Osnabrück</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Karl Eugen</namePart>
<namePart type="family">Hauptmann</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Krankenhaus der Barmherzigen Brüder, Kardiologie, Trier</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Hubert</namePart>
<namePart type="family">Seggewiß</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Klinikum Schweinfurt, Kardiologie, Schweinfurt</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Ilse</namePart>
<namePart type="family">Janicke</namePart>
<namePart type="termsOfAddress">MD</namePart>
<affiliation>Herzzentrum, Kardiologie, Duisburg</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Harald</namePart>
<namePart type="family">Mudra</namePart>
<namePart type="termsOfAddress">MD, FESC</namePart>
<affiliation>Herzzentrum, Kardiologie, Duisburg</affiliation>
<role>
<roleTerm type="text">author</roleTerm>
</role>
</name>
<name type="personal">
<namePart type="given">Jochen</namePart>
<namePart type="family">Senges</namePart>
<namePart type="termsOfAddress">MD, FACC, FESC</namePart>
<affiliation>Institut für Herzinfarktforschung, Ludwigshafen, Germany</affiliation>
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<roleTerm type="text">author</roleTerm>
</role>
</name>
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<place>
<placeTerm type="text">Hoboken</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2009-07-01</dateIssued>
<dateCaptured encoding="w3cdtf">2008-10-12</dateCaptured>
<dateValid encoding="w3cdtf">2008-10-29</dateValid>
<copyrightDate encoding="w3cdtf">2009</copyrightDate>
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<abstract lang="en">Objectives: To determine the influence of the side intervened upon on outcomes during carotid artery stenting (CAS). Background: Anatomic and technical aspects may influence the results of CAS. The value of the side intervened upon has not been analyzed yet. Methods: We analyzed data from the Carotid Artery Stent (CAS) – Registry. Results: A total of 3,165 CAS procedures, 1,613 (51%) at the left and 1,552 (49%) at the right carotid artery were included. There was a higher proportion of patients treated for symptomatic stenoses when CAS was performed at the left carotid artery (50.1% versus 45.8%, P = 0.016) and more patients already had prior carotid endarterectomy (8.5% versus 5.8%, P = 0.003). Interventions at the left side took 3 min longer than interventions at the right side (46.6 ± 24.3 versus 43.8 ± 23.6, P = 0.003). In patients treated at the left carotid artery amaurosis fugax (0.7% versus 0.1%, P = 0.005), ipsilateral stroke (3.1% versus 1.8%, P = 0.017), and the primary endpoint of in‐hospital death or stroke (4.1% versus 2.3%, P = 0.005) occurred significantly more often. Even after adjusting for confounding parameters, CAS procedures performed at the left carotid arteries remained an independent predictor of death or stroke (OR = 1.77, 95% CI: 1.15–2.72, P = 0.009). Conclusions: In current clinical practice, CAS is performed frequently at the right carotid artery as at the left carotid artery. CAS interventions have a higher in‐hospital complication rate if performed at the left carotid artery. Technical improvements might help to overcome this situation. © 2009 Wiley‐Liss, Inc.</abstract>
<note type="content">*Conflict of interest: Drs. Zahn, Ischinger, and Mudra have received travel expenses or payment for speaking at meetings from one or more companies which produces or distributes embolic protection devices or carotid stents.</note>
<subject lang="en">
<genre>keywords</genre>
<topic>carotid artery stenosis</topic>
<topic>carotid artery stenting</topic>
<topic>angioplasty</topic>
<topic>intervention side</topic>
</subject>
<relatedItem type="host">
<titleInfo>
<title>Catheterization and Cardiovascular Interventions</title>
</titleInfo>
<titleInfo type="abbreviated">
<title>Cathet. Cardiovasc. Intervent.</title>
</titleInfo>
<genre type="journal">journal</genre>
<subject>
<genre>article-category</genre>
<topic>Peripheral Vascular Disease</topic>
</subject>
<identifier type="ISSN">1522-1946</identifier>
<identifier type="eISSN">1522-726X</identifier>
<identifier type="DOI">10.1002/(ISSN)1522-726X</identifier>
<identifier type="PublisherID">CCD</identifier>
<part>
<date>2009</date>
<detail type="volume">
<caption>vol.</caption>
<number>74</number>
</detail>
<detail type="issue">
<caption>no.</caption>
<number>1</number>
</detail>
<extent unit="pages">
<start>1</start>
<end>8</end>
<total>8</total>
</extent>
</part>
</relatedItem>
<relatedItem type="preceding">
<titleInfo>
<title>Catheterization and Cardiovascular Diagnosis</title>
</titleInfo>
<identifier type="ISSN">0098-6569</identifier>
<identifier type="ISSN">1097-0304</identifier>
<part>
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<detail type="volume">
<caption>last vol.</caption>
<number>45</number>
</detail>
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<number>4</number>
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<identifier type="istex">B02FEE693FC770FDD7B3ACD8544CF427D7DDC16F</identifier>
<identifier type="DOI">10.1002/ccd.22050</identifier>
<identifier type="ArticleID">CCD22050</identifier>
<accessCondition type="use and reproduction" contentType="copyright">Copyright © 2009 Wiley‐Liss, Inc.</accessCondition>
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