Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa
Identifieur interne : 001218 ( Istex/Corpus ); précédent : 001217; suivant : 001219Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa
Auteurs : Peter Neudeck ; Georg E. Jacoby ; Irmela FlorinSource :
- Physiology & Behavior [ 0031-9384 ] ; 2001.
English descriptors
Abstract
The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; N=48) and healthy controls (N=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.
Url:
DOI: 10.1016/S0031-9384(00)00387-5
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title><author><name sortKey="Neudeck, Peter" sort="Neudeck, Peter" uniqKey="Neudeck P" first="Peter" last="Neudeck">Peter Neudeck</name><affiliation><mods:affiliation>E-mail: cds_berlin@t-online.de</mods:affiliation></affiliation><affiliation><mods:affiliation>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</mods:affiliation></affiliation></author><author><name sortKey="Jacoby, Georg E" sort="Jacoby, Georg E" uniqKey="Jacoby G" first="Georg E" last="Jacoby">Georg E. Jacoby</name><affiliation><mods:affiliation>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Florin, Irmela" sort="Florin, Irmela" uniqKey="Florin I" first="Irmela" last="Florin">Irmela Florin</name><affiliation><mods:affiliation>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1016/S0031-9384(00)00387-5</idno><idno type="url">https://api.istex.fr/document/76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001218</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001218</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title><author><name sortKey="Neudeck, Peter" sort="Neudeck, Peter" uniqKey="Neudeck P" first="Peter" last="Neudeck">Peter Neudeck</name><affiliation><mods:affiliation>E-mail: cds_berlin@t-online.de</mods:affiliation></affiliation><affiliation><mods:affiliation>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</mods:affiliation></affiliation></author><author><name sortKey="Jacoby, Georg E" sort="Jacoby, Georg E" uniqKey="Jacoby G" first="Georg E" last="Jacoby">Georg E. Jacoby</name><affiliation><mods:affiliation>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</mods:affiliation></affiliation></author><author><name sortKey="Florin, Irmela" sort="Florin, Irmela" uniqKey="Florin I" first="Irmela" last="Florin">Irmela Florin</name><affiliation><mods:affiliation>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Physiology & Behavior</title><title level="j" type="abbrev">PHB</title><idno type="ISSN">0031-9384</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001">2001</date><biblScope unit="volume">72</biblScope><biblScope unit="issue">1–2</biblScope><biblScope unit="page" from="93">93</biblScope><biblScope unit="page" to="98">98</biblScope></imprint><idno type="ISSN">0031-9384</idno></series><idno type="istex">76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A</idno><idno type="DOI">10.1016/S0031-9384(00)00387-5</idno><idno type="PII">S0031-9384(00)00387-5</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0031-9384</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bulimia</term><term>Dexamethasone suppression test</term><term>Salivary cortisol</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; N=48) and healthy controls (N=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Peter Neudeck</name><affiliations><json:string>E-mail: cds_berlin@t-online.de</json:string><json:string>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</json:string></affiliations></json:item><json:item><name>Georg E Jacoby</name><affiliations><json:string>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</json:string></affiliations></json:item><json:item><name>Irmela Florin</name><affiliations><json:string>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Dexamethasone suppression test</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Bulimia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Salivary cortisol</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; N=48) and healthy controls (N=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.</abstract><qualityIndicators><score>6.228</score><pdfVersion>1.2</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>3</keywordCount><abstractCharCount>1411</abstractCharCount><pdfWordCount>3792</pdfWordCount><pdfCharCount>23019</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>203</abstractWordCount></qualityIndicators><title>Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title><pii><json:string>S0031-9384(00)00387-5</json:string></pii><refBibs><json:item><author><json:item><name>JI Hudson</name></json:item><json:item><name>PS Laffer</name></json:item><json:item><name>HG Pope</name></json:item></author><host><volume>135</volume><pages><last>687</last><first>685</first></pages><author></author><title>Am J Psychiatry</title></host><title>Bulimia related to affective 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Pathophysical mechanisms in underweight and weight corrected patients</title></json:item><json:item><author><json:item><name>RF Vining</name></json:item><json:item><name>RA McGinley</name></json:item></author><host><volume>27</volume><pages><last>94</last><first>81</first></pages><author></author><title>J Steroid Biochem</title></host><title>The measurement of hormones in saliva: possibilities and pitfalls</title></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>72</volume><pii><json:string>S0031-9384(00)X0072-8</json:string></pii><pages><last>98</last><first>93</first></pages><issn><json:string>0031-9384</json:string></issn><issue>1–2</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><title>Physiology & Behavior</title><publicationDate>2001</publicationDate></host><categories><wos><json:string>social science</json:string><json:string>psychology, biological</json:string><json:string>science</json:string><json:string>behavioral sciences</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>psychology & cognitive sciences</json:string><json:string>behavioral science & comparative psychology</json:string></scienceMetrix></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1016/S0031-9384(00)00387-5</json:string></doi><id>76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A</id><score>0.024304172</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>©2001 Elsevier Science Inc.</p></availability><date>2001</date></publicationStmt><notesStmt><note>Statement of informed consent: We ensure that all subjects were informed about the aim of the study, especially about the use of dexamethasone. The experiment was authorized by the “Ethik Kommision” of the German Society of Psychology.</note><note type="content">Table 1: Cortisol levels in saliva (nmol/l) under basal conditions (means and S.D.)</note><note type="content">Table 2: Cortisol levels in saliva (nmol/l) after 1.5-mg DEX (means and S.D.)</note><note type="content">Table 3: Differences between bulimic suppressors and nonsuppressors for chosen variables</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title><author xml:id="author-1"><persName><forename type="first">Peter</forename><surname>Neudeck</surname></persName><email>cds_berlin@t-online.de</email><note type="correspondence"><p>Corresponding author. Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117 Berlin. Tel.: +49-30-25298473; fax: +49-0-30-25298470</p></note><affiliation>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</affiliation></author><author xml:id="author-2"><persName><forename type="first">Georg E</forename><surname>Jacoby</surname></persName><affiliation>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</affiliation></author><author xml:id="author-3"><persName><forename type="first">Irmela</forename><surname>Florin</surname></persName><note type="biography">Deceased in December 1998.</note><affiliation>Deceased in December 1998.</affiliation><affiliation>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</affiliation></author></analytic><monogr><title level="j">Physiology & Behavior</title><title level="j" type="abbrev">PHB</title><idno type="pISSN">0031-9384</idno><idno type="PII">S0031-9384(00)X0072-8</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2001"></date><biblScope unit="volume">72</biblScope><biblScope unit="issue">1–2</biblScope><biblScope unit="page" from="93">93</biblScope><biblScope unit="page" to="98">98</biblScope></imprint></monogr><idno type="istex">76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A</idno><idno type="DOI">10.1016/S0031-9384(00)00387-5</idno><idno type="PII">S0031-9384(00)00387-5</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2001</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; N=48) and healthy controls (N=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Dexamethasone suppression test</term></item><item><term>Bulimia</term></item><item><term>Salivary cortisol</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2000-06-09">Modified</change><change when="2001">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: ce:floats; body; tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla" xml:lang="en"><item-info><jid>PHB</jid><aid>6231</aid><ce:pii>S0031-9384(00)00387-5</ce:pii><ce:doi>10.1016/S0031-9384(00)00387-5</ce:doi><ce:copyright type="full-transfer" year="2001">Elsevier Science Inc.</ce:copyright></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>Statement of informed consent: We ensure that all subjects were informed about the aim of the study, especially about the use of dexamethasone. The experiment was authorized by the “Ethik Kommision” of the German Society of Psychology.</ce:note-para></ce:article-footnote><ce:title>Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</ce:title><ce:author-group><ce:author><ce:given-name>Peter</ce:given-name><ce:surname>Neudeck</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="CORR1">*</ce:cross-ref><ce:e-address>cds_berlin@t-online.de</ce:e-address></ce:author><ce:author><ce:given-name>Georg E</ce:given-name><ce:surname>Jacoby</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Irmela</ce:given-name><ce:surname>Florin</ce:surname><ce:cross-ref refid="FN1"><ce:sup>1</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF3"><ce:sup>c</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>c</ce:label><ce:textfn>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</ce:textfn></ce:affiliation><ce:correspondence id="CORR1"><ce:label>*</ce:label><ce:text>Corresponding author. Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117 Berlin. Tel.: +49-30-25298473; fax: +49-0-30-25298470</ce:text></ce:correspondence><ce:footnote id="FN1"><ce:label>1</ce:label><ce:note-para>Deceased in December 1998.</ce:note-para></ce:footnote></ce:author-group><ce:date-received day="11" month="4" year="2000"></ce:date-received><ce:date-revised day="9" month="6" year="2000"></ce:date-revised><ce:date-accepted day="25" month="8" year="2000"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; <ce:italic>N</ce:italic>=48) and healthy controls (<ce:italic>N</ce:italic>=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords class="keyword"><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>Dexamethasone suppression test</ce:text></ce:keyword><ce:keyword><ce:text>Bulimia</ce:text></ce:keyword><ce:keyword><ce:text>Salivary cortisol</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Dexamethasone suppression test using saliva cortisol measurement in bulimia nervosa</title></titleInfo><name type="personal"><namePart type="given">Peter</namePart><namePart type="family">Neudeck</namePart><affiliation>E-mail: cds_berlin@t-online.de</affiliation><affiliation>Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117, Berlin, Germany</affiliation><description>Corresponding author. Christoph-Dornier Foundation for Clinical Psychology, Marienstraße 18, D-10117 Berlin. Tel.: +49-30-25298473; fax: +49-0-30-25298470</description><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Georg E</namePart><namePart type="family">Jacoby</namePart><affiliation>Klinik am Korso, Ostkorso 4, 32545 Bad Oeynhausen, Germany</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Irmela</namePart><namePart type="family">Florin</namePart><affiliation>Department of Psychology, Philipps University Marburg, Gutenbergstrasse 5, 35032 Marburg, Germany</affiliation><description>Deceased in December 1998.</description><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">2001</dateIssued><dateModified encoding="w3cdtf">2000-06-09</dateModified><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">The assessment of cortisol in saliva has been proven a valid and reliable reflection of the respective unbound hormone in blood. In the present study, a standard dexamethasone suppression test (DST) with measures of salivary cortisol levels was performed in bulimic women without depression (DSM-IV; N=48) and healthy controls (N=24) matched for age. Feedback sensitivity was assessed using the standard DST with pre- and post-measures of salivary cortisol. Subjects were divided into suppressors and nonsuppressors according to their post-DST levels. Bulimic suppressors and nonsuppressors were compared for their basal cortisol levels, body weight (body mass index, BMI), previous episodes of anorexia nervosa, and their results in psychometric tests. A total of 16 (33.3%) out of 48 women with bulimia nervosa (BN) failed to suppress in the DST. Basal salivary cortisol levels were elevated in bulimic nonsuppressors. Significant differences between suppressors and nonsuppressors were found for body weight and previous episodes of anorexia nervosa. The results are in accordance with recent findings. They support the hypothesized association between low body weight and DST nonsuppression. Using saliva cortisol in the standard DST could be advantageous for studying bulimic patients. Furthermore, the results show the importance of determining HPA reagibility when measuring cortisol in bulimic patients.</abstract><note>Statement of informed consent: We ensure that all subjects were informed about the aim of the study, especially about the use of dexamethasone. The experiment was authorized by the “Ethik Kommision” of the German Society of Psychology.</note><note type="content">Table 1: Cortisol levels in saliva (nmol/l) under basal conditions (means and S.D.)</note><note type="content">Table 2: Cortisol levels in saliva (nmol/l) after 1.5-mg DEX (means and S.D.)</note><note type="content">Table 3: Differences between bulimic suppressors and nonsuppressors for chosen variables</note><subject lang="en"><genre>Keywords</genre><topic>Dexamethasone suppression test</topic><topic>Bulimia</topic><topic>Salivary cortisol</topic></subject><relatedItem type="host"><titleInfo><title>Physiology & Behavior</title></titleInfo><titleInfo type="abbreviated"><title>PHB</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">200101</dateIssued></originInfo><identifier type="ISSN">0031-9384</identifier><identifier type="PII">S0031-9384(00)X0072-8</identifier><part><date>200101</date><detail type="volume"><number>72</number><caption>vol.</caption></detail><detail type="issue"><number>1–2</number><caption>no.</caption></detail><extent unit="issue pages"><start>1</start><end>290</end></extent><extent unit="pages"><start>93</start><end>98</end></extent></part></relatedItem><identifier type="istex">76B8CF98657BB6A8F3448AD2A46CEDADDCA06B0A</identifier><identifier type="DOI">10.1016/S0031-9384(00)00387-5</identifier><identifier type="PII">S0031-9384(00)00387-5</identifier><accessCondition type="use and reproduction" contentType="copyright">©2001 Elsevier Science Inc.</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>Elsevier Science Inc., ©2001</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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