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Central and peripheral noradrenalin regulation in eating disorders

Identifieur interne : 000B01 ( Istex/Corpus ); précédent : 000B00; suivant : 000B02

Central and peripheral noradrenalin regulation in eating disorders

Auteurs : K. M. Pirke

Source :

RBID : ISTEX:5F209A9B573B949A9457497DB0080F86A1B97C37

Abstract

Norepinephrine and its metabolites were studied in various body fluids (plasma, urine and cerebrospinal fluid) of patients with anorexia nervosa, bulimia nervosa and healthy young women. The reaction of plasma norepinephrine to different stimuli like orthostatic challenge, test meals, standardized exercise, mental challenge tests etc. were studied. All results indicate a reduced noradrenergic activity in the central and peripheral nervous system of patients with eating disorders. The clinical consequences of these changes are hypotension, bradicardia, hypothermia and depression. Evidence is presented that the reduced activity of the sympathetic nervous system is caused by starvation (anorexia nervosa) or intermittent dieting (bulimia nervosa).

Url:
DOI: 10.1016/0165-1781(96)02982-4

Links to Exploration step

ISTEX:5F209A9B573B949A9457497DB0080F86A1B97C37

Le document en format XML

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