Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques
Identifieur interne : 000111 ( Pmc/Corpus ); précédent : 000110; suivant : 000112Noncytolytic CD8+ Cell Mediated Antiviral Response Represents a Strong Element in the Immune Response of Simian Immunodeficiency Virus-Infected Long-Term Non-Progressing Rhesus Macaques
Auteurs : Aneela Javed ; Nicole Leuchte ; Berit Neumann ; Sieghart Sopper ; Ulrike SauermannSource :
- PLoS ONE ; 2015.
Abstract
The ability of long term non progressors to maintain very low levels of HIV/SIV and a healthy state, involves various host genetic and immunological factors. CD8+ non-cytolytic antiviral response (CNAR) most likely plays an important role in this regard. In order to gain a deeper insight into this unique phenomenon, the ability of CD8+ T cells to suppress viral replication
Url:
DOI: 10.1371/journal.pone.0142086
PubMed: 26551355
PubMed Central: 4638345
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