Q FEVER STUDIES IN SOUTHERN CALIFORNIA
Identifieur interne : 002540 ( Main/Exploration ); précédent : 002539; suivant : 002541Q FEVER STUDIES IN SOUTHERN CALIFORNIA
Auteurs : Laubi Luoto ; John F. Winn [États-Unis] ; Robert J. HuebnerSource :
- American Journal of Epidemiology [ 0002-9262 ] ; 1952-03.
Abstract
1. A pilot study to determine the effectiveness of a killed vaccine in preventing bovine infection with Coxiella burneti was performed among adult dairy cattle which were replacements in 3 known infected dairies. 2. The occurrence of infection among cows that showed no evidence of infection at the beginning of the experiment was determined in 3 separate studies by two criteria: (a) the development of specific antibodies against C. burneti in the serum, and (b) the demonstration of C. burneti in the milk of such animals during 3 to 9 months of exposure in naturally infected dairy environs. 3. The high susceptibility of cows to Q fever and the occurrence of suitable exposure to the disease were, demonstrated by the fact that up to 50 per cent of the cows constituting the control group showed evidence of infection. 4. The vaccine can be considered to have engendered some resistance to infection, as 3 times as many nonvaccinated as vaccinated cows gave serological evidence of infection and 5 times as many nonvaceinated as vaccinated cows shed C. burneti in their milk during the period of observation. 5. The study suggests the possibility of the use of vaccine to control Q fever in dairy cattle and the need for further research and field studies on this phase of the problem.
Url:
DOI: 10.1093/oxfordjournals.aje.a119513
Affiliations:
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Winn</name><affiliation wicri:level="2"><country>États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Communicable Disease Center, Atlanta, Ga., assigned to the California State Department of Health, Viral and Rickettsial Laboratory Berkeley</wicri:cityArea></affiliation></author><author><name sortKey="Huebner, Robert J" sort="Huebner, Robert J" uniqKey="Huebner R" first="Robert J." last="Huebner">Robert J. Huebner</name><affiliation><wicri:noCountry code="subField">Md</wicri:noCountry></affiliation></author></analytic><monogr></monogr><series><title level="j">American Journal of Epidemiology</title><idno type="ISSN">0002-9262</idno><idno type="eISSN">1476-6256</idno><imprint><publisher>Oxford University Press</publisher><date type="published" when="1952-03">1952-03</date><biblScope unit="volume">55</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="190">190</biblScope><biblScope unit="page" to="202">202</biblScope></imprint><idno type="ISSN">0002-9262</idno></series><idno type="istex">AAB5DCCEE601ED47036ED6AB731770F6C0E54593</idno><idno type="DOI">10.1093/oxfordjournals.aje.a119513</idno><idno type="ArticleID">55.2.190</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0002-9262</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">1. A pilot study to determine the effectiveness of a killed vaccine in preventing bovine infection with Coxiella burneti was performed among adult dairy cattle which were replacements in 3 known infected dairies. 2. The occurrence of infection among cows that showed no evidence of infection at the beginning of the experiment was determined in 3 separate studies by two criteria: (a) the development of specific antibodies against C. burneti in the serum, and (b) the demonstration of C. burneti in the milk of such animals during 3 to 9 months of exposure in naturally infected dairy environs. 3. The high susceptibility of cows to Q fever and the occurrence of suitable exposure to the disease were, demonstrated by the fact that up to 50 per cent of the cows constituting the control group showed evidence of infection. 4. The vaccine can be considered to have engendered some resistance to infection, as 3 times as many nonvaccinated as vaccinated cows gave serological evidence of infection and 5 times as many nonvaceinated as vaccinated cows shed C. burneti in their milk during the period of observation. 5. The study suggests the possibility of the use of vaccine to control Q fever in dairy cattle and the need for further research and field studies on this phase of the problem.</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li></region></list><tree><noCountry><name sortKey="Huebner, Robert J" sort="Huebner, Robert J" uniqKey="Huebner R" first="Robert J." last="Huebner">Robert J. Huebner</name><name sortKey="Luoto, Laubi" sort="Luoto, Laubi" uniqKey="Luoto L" first="Laubi" last="Luoto">Laubi Luoto</name></noCountry><country name="États-Unis"><region name="Californie"><name sortKey="Winn, John F" sort="Winn, John F" uniqKey="Winn J" first="John F." last="Winn">John F. Winn</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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