[Which biological matrix for cannabis testing?].
Identifieur interne : 000295 ( PubMed/Curation ); précédent : 000294; suivant : 000296[Which biological matrix for cannabis testing?].
Auteurs : J-P Goullé [France] ; C. LacroixSource :
- Annales pharmaceutiques francaises [ 0003-4509 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Cannabinoids, Dronabinol.
- chemical , pharmacokinetics : Cannabinoids, Dronabinol.
- adverse effects : Cannabis.
- chemistry : Cannabis.
- Automobile Driving, Humans, Tissue Distribution.
Abstract
Decisive analytical progress for biological cannabis testing has been achieved over the past ten years. These major contributions allow to accurately identify and quantify in detail the substances present in the body following cannabinoid exposure. Fast and reliable onsite urine testing is used to implement the French law on narcotic drugs and its relationship to motorway safety. A positive test result will indicate a very recent exposure which is detectable up to five days following intake. Then a clinical examination and blood collection are performed by a physician, with a subsequent blood tetrahydrocannabinol (THC) analysis by authorized professionals registered at the judicial court of appeal. A result higher than the cut-off value is associated with a very recent cannabis exposure. Blood, urine, saliva and sweat cannabis determination are assessed according to the most recent pharmacokinetic and analytical data.
PubMed: 16710116
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pubmed:16710116Le document en format XML
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<author><name sortKey="Goulle, J P" sort="Goulle, J P" uniqKey="Goulle J" first="J-P" last="Goullé">J-P Goullé</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratoire de pharmacocinétique et de toxicologie cliniques, Groupe hospitalier du Havre, BP 24, F 76083 Le Havre Cedex. jgoulle@ch-havre.fr</nlm:affiliation>
<country wicri:rule="url">France</country>
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<author><name sortKey="Lacroix, C" sort="Lacroix, C" uniqKey="Lacroix C" first="C" last="Lacroix">C. Lacroix</name>
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<author><name sortKey="Goulle, J P" sort="Goulle, J P" uniqKey="Goulle J" first="J-P" last="Goullé">J-P Goullé</name>
<affiliation wicri:level="1"><nlm:affiliation>Laboratoire de pharmacocinétique et de toxicologie cliniques, Groupe hospitalier du Havre, BP 24, F 76083 Le Havre Cedex. jgoulle@ch-havre.fr</nlm:affiliation>
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<series><title level="j">Annales pharmaceutiques francaises</title>
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<imprint><date when="2006" type="published">2006</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Automobile Driving</term>
<term>Cannabinoids (analysis)</term>
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<term>Cannabis (adverse effects)</term>
<term>Cannabis (chemistry)</term>
<term>Dronabinol (analysis)</term>
<term>Dronabinol (pharmacokinetics)</term>
<term>Humans</term>
<term>Tissue Distribution</term>
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<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Cannabinoids</term>
<term>Dronabinol</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Cannabinoids</term>
<term>Dronabinol</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Cannabis</term>
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<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Cannabis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Automobile Driving</term>
<term>Humans</term>
<term>Tissue Distribution</term>
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<front><div type="abstract" xml:lang="en">Decisive analytical progress for biological cannabis testing has been achieved over the past ten years. These major contributions allow to accurately identify and quantify in detail the substances present in the body following cannabinoid exposure. Fast and reliable onsite urine testing is used to implement the French law on narcotic drugs and its relationship to motorway safety. A positive test result will indicate a very recent exposure which is detectable up to five days following intake. Then a clinical examination and blood collection are performed by a physician, with a subsequent blood tetrahydrocannabinol (THC) analysis by authorized professionals registered at the judicial court of appeal. A result higher than the cut-off value is associated with a very recent cannabis exposure. Blood, urine, saliva and sweat cannabis determination are assessed according to the most recent pharmacokinetic and analytical data.</div>
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<DateRevised><Year>2013</Year>
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<JournalIssue CitedMedium="Print"><Volume>64</Volume>
<Issue>3</Issue>
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<Title>Annales pharmaceutiques francaises</Title>
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<ArticleTitle>[Which biological matrix for cannabis testing?].</ArticleTitle>
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<Abstract><AbstractText>Decisive analytical progress for biological cannabis testing has been achieved over the past ten years. These major contributions allow to accurately identify and quantify in detail the substances present in the body following cannabinoid exposure. Fast and reliable onsite urine testing is used to implement the French law on narcotic drugs and its relationship to motorway safety. A positive test result will indicate a very recent exposure which is detectable up to five days following intake. Then a clinical examination and blood collection are performed by a physician, with a subsequent blood tetrahydrocannabinol (THC) analysis by authorized professionals registered at the judicial court of appeal. A result higher than the cut-off value is associated with a very recent cannabis exposure. Blood, urine, saliva and sweat cannabis determination are assessed according to the most recent pharmacokinetic and analytical data.</AbstractText>
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<Initials>JP</Initials>
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<VernacularTitle>Mise en évidence des cannabinoïdes: quel milieu biologique?</VernacularTitle>
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<MeshHeading><DescriptorName UI="D013759" MajorTopicYN="N">Dronabinol</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D014018" MajorTopicYN="N">Tissue Distribution</DescriptorName>
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