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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Plasma and Urinary Aluminum Concentrations in Severely Anemic Geophagous Pregnant Women in the Bas Maroni Region of French Guiana: A Case-Control Study</title><author><name sortKey="Lambert, Veronique" sort="Lambert, Veronique" uniqKey="Lambert V" first="Veronique" last="Lambert">Veronique Lambert</name></author><author><name sortKey="Boukhari, Rachida" sort="Boukhari, Rachida" uniqKey="Boukhari R" first="Rachida" last="Boukhari">Rachida Boukhari</name></author><author><name sortKey="Nacher, Mathieu" sort="Nacher, Mathieu" uniqKey="Nacher M" first="Mathieu" last="Nacher">Mathieu Nacher</name></author><author><name sortKey="Goulle, Jean Pierre" sort="Goulle, Jean Pierre" uniqKey="Goulle J" first="Jean-Pierre" last="Goullé">Jean-Pierre Goullé</name></author><author><name sortKey="Roudier, Estelle" sort="Roudier, Estelle" uniqKey="Roudier E" first="Estelle" last="Roudier">Estelle Roudier</name></author><author><name sortKey="Elguindi, Wael" sort="Elguindi, Wael" uniqKey="Elguindi W" first="Wael" last="Elguindi">Wael Elguindi</name></author><author><name sortKey="Laquerriere, Annie" sort="Laquerriere, Annie" uniqKey="Laquerriere A" first="Annie" last="Laquerrière">Annie Laquerrière</name></author><author><name sortKey="Carles, Gabriel" sort="Carles, Gabriel" uniqKey="Carles G" first="Gabriel" last="Carles">Gabriel Carles</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21036845</idno><idno type="pmc">2963977</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963977</idno><idno type="RBID">PMC:2963977</idno><idno type="doi">10.4269/ajtmh.2010.10-0370</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">000173</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Plasma and Urinary Aluminum Concentrations in Severely Anemic Geophagous Pregnant Women in the Bas Maroni Region of French Guiana: A Case-Control Study</title><author><name sortKey="Lambert, Veronique" sort="Lambert, Veronique" uniqKey="Lambert V" first="Veronique" last="Lambert">Veronique Lambert</name></author><author><name sortKey="Boukhari, Rachida" sort="Boukhari, Rachida" uniqKey="Boukhari R" first="Rachida" last="Boukhari">Rachida Boukhari</name></author><author><name sortKey="Nacher, Mathieu" sort="Nacher, Mathieu" uniqKey="Nacher M" first="Mathieu" last="Nacher">Mathieu Nacher</name></author><author><name sortKey="Goulle, Jean Pierre" sort="Goulle, Jean Pierre" uniqKey="Goulle J" first="Jean-Pierre" last="Goullé">Jean-Pierre Goullé</name></author><author><name sortKey="Roudier, Estelle" sort="Roudier, Estelle" uniqKey="Roudier E" first="Estelle" last="Roudier">Estelle Roudier</name></author><author><name sortKey="Elguindi, Wael" sort="Elguindi, Wael" uniqKey="Elguindi W" first="Wael" last="Elguindi">Wael Elguindi</name></author><author><name sortKey="Laquerriere, Annie" sort="Laquerriere, Annie" uniqKey="Laquerriere A" first="Annie" last="Laquerrière">Annie Laquerrière</name></author><author><name sortKey="Carles, Gabriel" sort="Carles, Gabriel" uniqKey="Carles G" first="Gabriel" last="Carles">Gabriel Carles</name></author></analytic><series><title level="j">The American Journal of Tropical Medicine and Hygiene</title><idno type="ISSN">0002-9637</idno><idno type="eISSN">1476-1645</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The clays consumed by geophagous individuals contain large quantities of aluminum, a known neurological and hematological toxin. This is the first study to evaluate the risk of aluminum poisoning in geophagous individuals. Blind determinations of plasma and urinary aluminum concentrations were carried out in 98 anemic geophagous pregnant women and 85 non-anemic non-geophagous pregnant women. Aluminum concentrations were significantly higher (<italic>P</italic> < 0.0001) in the geophagous anemic women than in the controls, with odds ratios of 6.83 (95% confidence interval [CI] = 2.72–19.31) for plasma concentrations (13.92 ± 14.09 μg/L versus 4.95 ± 7.11 μg/L) and 5.44 (95% CI = 2.17–14.8) for urinary concentrations (92.83 ± 251.21 μg/L versus 12.11 ± 23 μg/L). The ingested clay is the most likely source of this overexposure to aluminum. If confirmed, the clinical consequences of this absorption for pregnant women and their offspring should be explored.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Am J Trop Med Hyg</journal-id><journal-id journal-id-type="publisher-id">tpmd</journal-id><journal-title-group><journal-title>The American Journal of Tropical Medicine and Hygiene</journal-title></journal-title-group><issn pub-type="ppub">0002-9637</issn><issn pub-type="epub">1476-1645</issn><publisher><publisher-name>The American Society of Tropical Medicine and Hygiene</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21036845</article-id><article-id pub-id-type="pmc">2963977</article-id><article-id pub-id-type="doi">10.4269/ajtmh.2010.10-0370</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Plasma and Urinary Aluminum Concentrations in Severely Anemic Geophagous Pregnant Women in the Bas Maroni Region of French Guiana: A Case-Control Study</article-title><alt-title alt-title-type="left-running-head">LAMBERT AND OTHERS</alt-title><alt-title alt-title-type="right-running-head">ALUMINUM IN GEOPHAGOUS PREGNANT WOMEN</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Lambert</surname><given-names>Veronique</given-names></name><xref ref-type="corresp" rid="COR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Boukhari</surname><given-names>Rachida</given-names></name></contrib><contrib contrib-type="author"><name><surname>Nacher</surname><given-names>Mathieu</given-names></name></contrib><contrib contrib-type="author"><name><surname>Goullé</surname><given-names>Jean-Pierre</given-names></name></contrib><contrib contrib-type="author"><name><surname>Roudier</surname><given-names>Estelle</given-names></name></contrib><contrib contrib-type="author"><name><surname>Elguindi</surname><given-names>Wael</given-names></name></contrib><contrib contrib-type="author"><name><surname>Laquerrière</surname><given-names>Annie</given-names></name></contrib><contrib contrib-type="author"><name><surname>Carles</surname><given-names>Gabriel</given-names></name></contrib></contrib-group><aff id="AFF1">Service de Gynécologie Obstétrique, Centre Hospitalier de l'Ouest Guyanais, Saint Laurent du Maroni, Guyane Française; Service de Biologie Médicale, Centre Hospitalier de l'Ouest Guyanais, Saint Laurent du Maroni, Guyane Française; Centre d'Investigations Cliniques et Epidémiologie Clinique Antilles Guyane, Centre Hospitalier de Cayenne, Cayenne, Guyane Française; Laboratoire de Toxicologie, Groupe Hospitalier du Havre, Le Havre, France; Laboratoire de Pathologie, Centre Hospitalier Universitaire de Rouen, Rouen, France</aff><author-notes><corresp id="COR1">*Address correspondence to Veronique Lambert, Service de Gynécologie Obstétrique and Service de Biologie Medicale, Centre Hospitalier de l'Ouest Guyanais, 97320 Saint Laurent du Maroni, French Guiana. E-mail: <email>v.lambert@ch-ouestguyane.fr</email></corresp></author-notes><pub-date pub-type="ppub"><day>05</day><month>11</month><year>2010</year></pub-date><volume>83</volume><issue>5</issue><fpage>1100</fpage><lpage>1105</lpage><history><date date-type="received"><day>29</day><month>6</month><year>2010</year></date><date date-type="accepted"><day>31</day><month>7</month><year>2010</year></date></history><permissions><copyright-statement>©The American Society of Tropical Medicine and Hygiene</copyright-statement><copyright-year>2010</copyright-year></permissions><abstract><p>The clays consumed by geophagous individuals contain large quantities of aluminum, a known neurological and hematological toxin. This is the first study to evaluate the risk of aluminum poisoning in geophagous individuals. Blind determinations of plasma and urinary aluminum concentrations were carried out in 98 anemic geophagous pregnant women and 85 non-anemic non-geophagous pregnant women. Aluminum concentrations were significantly higher (<italic>P</italic> < 0.0001) in the geophagous anemic women than in the controls, with odds ratios of 6.83 (95% confidence interval [CI] = 2.72–19.31) for plasma concentrations (13.92 ± 14.09 μg/L versus 4.95 ± 7.11 μg/L) and 5.44 (95% CI = 2.17–14.8) for urinary concentrations (92.83 ± 251.21 μg/L versus 12.11 ± 23 μg/L). The ingested clay is the most likely source of this overexposure to aluminum. If confirmed, the clinical consequences of this absorption for pregnant women and their offspring should be explored.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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