Cloning of a second proopiomelanocortin cDNA from the pituitary of the sturgeon, Acipenser transmontanus.
Identifieur interne : 000662 ( PubMed/Curation ); précédent : 000661; suivant : 000663Cloning of a second proopiomelanocortin cDNA from the pituitary of the sturgeon, Acipenser transmontanus.
Auteurs : J. Alrubaian [États-Unis] ; P. Danielson ; M. Fitzpatrick ; C. Schreck ; R M DoresSource :
- Peptides [ 0196-9781 ] ; 1999.
English descriptors
- KwdEn :
- Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, DNA, Complementary (genetics), Fishes (genetics), Gene Duplication, Molecular Sequence Data, Open Reading Frames, Pituitary Gland (chemistry), Point Mutation, Pro-Opiomelanocortin (genetics), Sequence Analysis, DNA, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid.
- MESH :
- chemical , genetics : DNA, Complementary, Pro-Opiomelanocortin.
- chemistry : Pituitary Gland.
- genetics : Fishes.
- Amino Acid Sequence, Animals, Base Sequence, Cloning, Molecular, Gene Duplication, Molecular Sequence Data, Open Reading Frames, Point Mutation, Sequence Analysis, DNA, Sequence Homology, Amino Acid, Sequence Homology, Nucleic Acid.
Abstract
A recent study on the pituitary of the sturgeon, Acipenser transmontanus, resulted in the cloning of a cDNA that codes for the prohormone, proopiomelanocortin (POMC). This cDNA is designated sturgeon POMC A. Subsequent analysis of the sturgeon pituitary uncovered a second distinct POMC cDNA (sturgeon POMC B). In both sturgeon POMC cDNAs the open reading frame is 795 nucleotides in length. However, the two sturgeon POMC cDNAs differ at 26 amino acid positions in the opening frame. In addition, the 2 forms of POMC differ at 45 nucleotide positions within the open reading frame. The number and types of point mutations are compared in the 2 sturgeons POMC cDNAs, and the origin of the two POMC genes is discussed.
PubMed: 10458511
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Schreck</name></author><author><name sortKey="Dores, R M" sort="Dores, R M" uniqKey="Dores R" first="R M" last="Dores">R M Dores</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1999">1999</date><idno type="RBID">pubmed:10458511</idno><idno type="pmid">10458511</idno><idno type="wicri:Area/PubMed/Corpus">000662</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000662</idno><idno type="wicri:Area/PubMed/Curation">000662</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000662</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Cloning of a second proopiomelanocortin cDNA from the pituitary of the sturgeon, Acipenser transmontanus.</title><author><name sortKey="Alrubaian, J" sort="Alrubaian, J" uniqKey="Alrubaian J" first="J" last="Alrubaian">J. Alrubaian</name><affiliation wicri:level="1"><nlm:affiliation>University of Denver, Department of Biological Sciences, Colorado 80208, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Denver, Department of Biological Sciences, Colorado 80208</wicri:regionArea></affiliation></author><author><name sortKey="Danielson, P" sort="Danielson, P" uniqKey="Danielson P" first="P" last="Danielson">P. Danielson</name></author><author><name sortKey="Fitzpatrick, M" sort="Fitzpatrick, M" uniqKey="Fitzpatrick M" first="M" last="Fitzpatrick">M. Fitzpatrick</name></author><author><name sortKey="Schreck, C" sort="Schreck, C" uniqKey="Schreck C" first="C" last="Schreck">C. Schreck</name></author><author><name sortKey="Dores, R M" sort="Dores, R M" uniqKey="Dores R" first="R M" last="Dores">R M Dores</name></author></analytic><series><title level="j">Peptides</title><idno type="ISSN">0196-9781</idno><imprint><date when="1999" type="published">1999</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term><term>Animals</term><term>Base Sequence</term><term>Cloning, Molecular</term><term>DNA, Complementary (genetics)</term><term>Fishes (genetics)</term><term>Gene Duplication</term><term>Molecular Sequence Data</term><term>Open Reading Frames</term><term>Pituitary Gland (chemistry)</term><term>Point Mutation</term><term>Pro-Opiomelanocortin (genetics)</term><term>Sequence Analysis, DNA</term><term>Sequence Homology, Amino Acid</term><term>Sequence Homology, Nucleic Acid</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>DNA, Complementary</term><term>Pro-Opiomelanocortin</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Pituitary Gland</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Fishes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Animals</term><term>Base Sequence</term><term>Cloning, Molecular</term><term>Gene Duplication</term><term>Molecular Sequence Data</term><term>Open Reading Frames</term><term>Point Mutation</term><term>Sequence Analysis, DNA</term><term>Sequence Homology, Amino Acid</term><term>Sequence Homology, Nucleic Acid</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A recent study on the pituitary of the sturgeon, Acipenser transmontanus, resulted in the cloning of a cDNA that codes for the prohormone, proopiomelanocortin (POMC). This cDNA is designated sturgeon POMC A. Subsequent analysis of the sturgeon pituitary uncovered a second distinct POMC cDNA (sturgeon POMC B). In both sturgeon POMC cDNAs the open reading frame is 795 nucleotides in length. However, the two sturgeon POMC cDNAs differ at 26 amino acid positions in the opening frame. In addition, the 2 forms of POMC differ at 45 nucleotide positions within the open reading frame. The number and types of point mutations are compared in the 2 sturgeons POMC cDNAs, and the origin of the two POMC genes is discussed.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10458511</PMID><DateCreated><Year>1999</Year><Month>10</Month><Day>26</Day></DateCreated><DateCompleted><Year>1999</Year><Month>10</Month><Day>26</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0196-9781</ISSN><JournalIssue CitedMedium="Print"><Volume>20</Volume><Issue>4</Issue><PubDate><Year>1999</Year></PubDate></JournalIssue><Title>Peptides</Title><ISOAbbreviation>Peptides</ISOAbbreviation></Journal><ArticleTitle>Cloning of a second proopiomelanocortin cDNA from the pituitary of the sturgeon, Acipenser transmontanus.</ArticleTitle><Pagination><MedlinePgn>431-6</MedlinePgn></Pagination><Abstract><AbstractText>A recent study on the pituitary of the sturgeon, Acipenser transmontanus, resulted in the cloning of a cDNA that codes for the prohormone, proopiomelanocortin (POMC). This cDNA is designated sturgeon POMC A. Subsequent analysis of the sturgeon pituitary uncovered a second distinct POMC cDNA (sturgeon POMC B). In both sturgeon POMC cDNAs the open reading frame is 795 nucleotides in length. However, the two sturgeon POMC cDNAs differ at 26 amino acid positions in the opening frame. In addition, the 2 forms of POMC differ at 45 nucleotide positions within the open reading frame. The number and types of point mutations are compared in the 2 sturgeons POMC cDNAs, and the origin of the two POMC genes is discussed.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Alrubaian</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>University of Denver, Department of Biological Sciences, Colorado 80208, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Danielson</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Fitzpatrick</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Schreck</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Dores</LastName><ForeName>R M</ForeName><Initials>RM</Initials></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>GENBANK</DataBankName><AccessionNumberList><AccessionNumber>AF092936</AccessionNumber><AccessionNumber>AF092937</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Peptides</MedlineTA><NlmUniqueID>8008690</NlmUniqueID><ISSNLinking>0196-9781</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D018076">DNA, Complementary</NameOfSubstance></Chemical><Chemical><RegistryNumber>66796-54-1</RegistryNumber><NameOfSubstance UI="D011333">Pro-Opiomelanocortin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001483" MajorTopicYN="N">Base Sequence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003001" MajorTopicYN="N">Cloning, Molecular</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018076" MajorTopicYN="N">DNA, Complementary</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005399" MajorTopicYN="N">Fishes</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020440" MajorTopicYN="N">Gene Duplication</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016366" MajorTopicYN="N">Open Reading Frames</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010902" MajorTopicYN="N">Pituitary Gland</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017354" MajorTopicYN="N">Point Mutation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011333" MajorTopicYN="N">Pro-Opiomelanocortin</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017422" MajorTopicYN="N">Sequence Analysis, DNA</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017386" MajorTopicYN="N">Sequence Homology, Amino Acid</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012689" MajorTopicYN="N">Sequence Homology, Nucleic Acid</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1999</Year><Month>8</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1999</Year><Month>8</Month><Day>24</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1999</Year><Month>8</Month><Day>24</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">10458511</ArticleId><ArticleId IdType="pii">S0196-9781(99)00021-2</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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