Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.
Identifieur interne : 000463 ( PubMed/Checkpoint ); précédent : 000462; suivant : 000464Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.
Auteurs : Yi Wan [République populaire de Chine] ; Qiwei Wei ; Jianying Hu ; Xiaohui Jin ; Zhaobin Zhang ; Huajun Zhen ; Jianyi LiuSource :
- Environmental science & technology [ 0013-936X ] ; 2007.
English descriptors
- KwdEn :
- Adipose Tissue (chemistry), Animals, Benzopyrans (analysis), Benzopyrans (pharmacokinetics), China, Environmental Monitoring (statistics & numerical data), Female, Fishes (metabolism), Gas Chromatography-Mass Spectrometry, Perfume (analysis), Perfume (pharmacokinetics), Tetrahydronaphthalenes (analysis), Tetrahydronaphthalenes (pharmacokinetics), Tissue Distribution, Water Pollutants, Chemical (analysis), Water Pollutants, Chemical (pharmacokinetics), Xylenes (analysis), Xylenes (pharmacokinetics).
- MESH :
- chemical , analysis : Benzopyrans, Perfume, Tetrahydronaphthalenes, Water Pollutants, Chemical, Xylenes.
- chemistry : Adipose Tissue.
- metabolism : Fishes.
- chemical , pharmacokinetics : Benzopyrans, Perfume, Tetrahydronaphthalenes, Water Pollutants, Chemical, Xylenes.
- statistics & numerical data : Environmental Monitoring.
- Animals, China, Female, Gas Chromatography-Mass Spectrometry, Tissue Distribution.
Abstract
Chinese sturgeon (Acipenser sinensis) was listed as a Grade I protected animal in China in 1989, and the observed intersexual phenomenon and sex ratio deviation have suggested that chemicals have posed a risk as environment pollutants. This study analyzed seven musk fragrances in liver, muscle, heart, gonad, stomach, intestines, adipose, gill, pancreas, kidney, gallbladder, and roe from 13 female Chinese sturgeons, and the toxicokinetic behavior of musks were studied and compared with some organochlorines. Of the seven musks, HHCB, AHTN, and musk xylene were detected, and the highest concentrations were observed in adipose tissue: from 33.7 to 62.1 ng/g wet weight (ww), from 1.0 to 5.4 ng/g ww, and from 1.1 to 13 ng/g ww, respectively. Similar to the tissue distribution of DDTs and HCB, musks were detected frequently in high lipid content tissues such as roe, adipose, and liver, suggesting that tissue distribution of musks is controlled by the affinity to lipids. The concentration ratios based on lipid weight between roe and adipose were estimated to be 0.47 for HHCB, 0.58 for AHTN, and 0.51 for musk xylene, and those for the total DDTs and HCB were 0.27 and 0.61, which were relatively low compared with mammals. Relatively high concentrations of p,p'-DDE (68.4-449 ng/g ww) were detected in 10 of total 11 samples, which would cause the feminization of Chinese sturgeons during embryonic development. It was found that lipid-corrected concentrations of HHCB, AHTN, p,p'-DDE, and p,p'-DDD increased with age in female sturgeon, of which the trends were similar to those in fishes and different from those in mammals.
PubMed: 17310702
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:17310702Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.</title><author><name sortKey="Wan, Yi" sort="Wan, Yi" uniqKey="Wan Y" first="Yi" last="Wan">Yi Wan</name><affiliation wicri:level="4"><nlm:affiliation>College of Environmental Sciences, Peking University, Beijing, 100871, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Environmental Sciences, Peking University, Beijing, 100871</wicri:regionArea><orgName type="university">Université de Pékin</orgName><placeName><settlement type="city">Pékin</settlement><region type="capitale">Pékin</region></placeName></affiliation></author><author><name sortKey="Wei, Qiwei" sort="Wei, Qiwei" uniqKey="Wei Q" first="Qiwei" last="Wei">Qiwei Wei</name></author><author><name sortKey="Hu, Jianying" sort="Hu, Jianying" uniqKey="Hu J" first="Jianying" last="Hu">Jianying Hu</name></author><author><name sortKey="Jin, Xiaohui" sort="Jin, Xiaohui" uniqKey="Jin X" first="Xiaohui" last="Jin">Xiaohui Jin</name></author><author><name sortKey="Zhang, Zhaobin" sort="Zhang, Zhaobin" uniqKey="Zhang Z" first="Zhaobin" last="Zhang">Zhaobin Zhang</name></author><author><name sortKey="Zhen, Huajun" sort="Zhen, Huajun" uniqKey="Zhen H" first="Huajun" last="Zhen">Huajun Zhen</name></author><author><name sortKey="Liu, Jianyi" sort="Liu, Jianyi" uniqKey="Liu J" first="Jianyi" last="Liu">Jianyi Liu</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2007">2007</date><idno type="RBID">pubmed:17310702</idno><idno type="pmid">17310702</idno><idno type="wicri:Area/PubMed/Corpus">000499</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000499</idno><idno type="wicri:Area/PubMed/Curation">000499</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000499</idno><idno type="wicri:Area/PubMed/Checkpoint">000499</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000499</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.</title><author><name sortKey="Wan, Yi" sort="Wan, Yi" uniqKey="Wan Y" first="Yi" last="Wan">Yi Wan</name><affiliation wicri:level="4"><nlm:affiliation>College of Environmental Sciences, Peking University, Beijing, 100871, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>College of Environmental Sciences, Peking University, Beijing, 100871</wicri:regionArea><orgName type="university">Université de Pékin</orgName><placeName><settlement type="city">Pékin</settlement><region type="capitale">Pékin</region></placeName></affiliation></author><author><name sortKey="Wei, Qiwei" sort="Wei, Qiwei" uniqKey="Wei Q" first="Qiwei" last="Wei">Qiwei Wei</name></author><author><name sortKey="Hu, Jianying" sort="Hu, Jianying" uniqKey="Hu J" first="Jianying" last="Hu">Jianying Hu</name></author><author><name sortKey="Jin, Xiaohui" sort="Jin, Xiaohui" uniqKey="Jin X" first="Xiaohui" last="Jin">Xiaohui Jin</name></author><author><name sortKey="Zhang, Zhaobin" sort="Zhang, Zhaobin" uniqKey="Zhang Z" first="Zhaobin" last="Zhang">Zhaobin Zhang</name></author><author><name sortKey="Zhen, Huajun" sort="Zhen, Huajun" uniqKey="Zhen H" first="Huajun" last="Zhen">Huajun Zhen</name></author><author><name sortKey="Liu, Jianyi" sort="Liu, Jianyi" uniqKey="Liu J" first="Jianyi" last="Liu">Jianyi Liu</name></author></analytic><series><title level="j">Environmental science & technology</title><idno type="ISSN">0013-936X</idno><imprint><date when="2007" type="published">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adipose Tissue (chemistry)</term><term>Animals</term><term>Benzopyrans (analysis)</term><term>Benzopyrans (pharmacokinetics)</term><term>China</term><term>Environmental Monitoring (statistics & numerical data)</term><term>Female</term><term>Fishes (metabolism)</term><term>Gas Chromatography-Mass Spectrometry</term><term>Perfume (analysis)</term><term>Perfume (pharmacokinetics)</term><term>Tetrahydronaphthalenes (analysis)</term><term>Tetrahydronaphthalenes (pharmacokinetics)</term><term>Tissue Distribution</term><term>Water Pollutants, Chemical (analysis)</term><term>Water Pollutants, Chemical (pharmacokinetics)</term><term>Xylenes (analysis)</term><term>Xylenes (pharmacokinetics)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Benzopyrans</term><term>Perfume</term><term>Tetrahydronaphthalenes</term><term>Water Pollutants, Chemical</term><term>Xylenes</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Adipose Tissue</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Fishes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacokinetics" xml:lang="en"><term>Benzopyrans</term><term>Perfume</term><term>Tetrahydronaphthalenes</term><term>Water Pollutants, Chemical</term><term>Xylenes</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Environmental Monitoring</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>China</term><term>Female</term><term>Gas Chromatography-Mass Spectrometry</term><term>Tissue Distribution</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Chinese sturgeon (Acipenser sinensis) was listed as a Grade I protected animal in China in 1989, and the observed intersexual phenomenon and sex ratio deviation have suggested that chemicals have posed a risk as environment pollutants. This study analyzed seven musk fragrances in liver, muscle, heart, gonad, stomach, intestines, adipose, gill, pancreas, kidney, gallbladder, and roe from 13 female Chinese sturgeons, and the toxicokinetic behavior of musks were studied and compared with some organochlorines. Of the seven musks, HHCB, AHTN, and musk xylene were detected, and the highest concentrations were observed in adipose tissue: from 33.7 to 62.1 ng/g wet weight (ww), from 1.0 to 5.4 ng/g ww, and from 1.1 to 13 ng/g ww, respectively. Similar to the tissue distribution of DDTs and HCB, musks were detected frequently in high lipid content tissues such as roe, adipose, and liver, suggesting that tissue distribution of musks is controlled by the affinity to lipids. The concentration ratios based on lipid weight between roe and adipose were estimated to be 0.47 for HHCB, 0.58 for AHTN, and 0.51 for musk xylene, and those for the total DDTs and HCB were 0.27 and 0.61, which were relatively low compared with mammals. Relatively high concentrations of p,p'-DDE (68.4-449 ng/g ww) were detected in 10 of total 11 samples, which would cause the feminization of Chinese sturgeons during embryonic development. It was found that lipid-corrected concentrations of HHCB, AHTN, p,p'-DDE, and p,p'-DDD increased with age in female sturgeon, of which the trends were similar to those in fishes and different from those in mammals.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17310702</PMID><DateCreated><Year>2007</Year><Month>02</Month><Day>21</Day></DateCreated><DateCompleted><Year>2007</Year><Month>03</Month><Day>09</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>24</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0013-936X</ISSN><JournalIssue CitedMedium="Print"><Volume>41</Volume><Issue>2</Issue><PubDate><Year>2007</Year><Month>Jan</Month><Day>15</Day></PubDate></JournalIssue><Title>Environmental science & technology</Title><ISOAbbreviation>Environ. Sci. Technol.</ISOAbbreviation></Journal><ArticleTitle>Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.</ArticleTitle><Pagination><MedlinePgn>424-30</MedlinePgn></Pagination><Abstract><AbstractText>Chinese sturgeon (Acipenser sinensis) was listed as a Grade I protected animal in China in 1989, and the observed intersexual phenomenon and sex ratio deviation have suggested that chemicals have posed a risk as environment pollutants. This study analyzed seven musk fragrances in liver, muscle, heart, gonad, stomach, intestines, adipose, gill, pancreas, kidney, gallbladder, and roe from 13 female Chinese sturgeons, and the toxicokinetic behavior of musks were studied and compared with some organochlorines. Of the seven musks, HHCB, AHTN, and musk xylene were detected, and the highest concentrations were observed in adipose tissue: from 33.7 to 62.1 ng/g wet weight (ww), from 1.0 to 5.4 ng/g ww, and from 1.1 to 13 ng/g ww, respectively. Similar to the tissue distribution of DDTs and HCB, musks were detected frequently in high lipid content tissues such as roe, adipose, and liver, suggesting that tissue distribution of musks is controlled by the affinity to lipids. The concentration ratios based on lipid weight between roe and adipose were estimated to be 0.47 for HHCB, 0.58 for AHTN, and 0.51 for musk xylene, and those for the total DDTs and HCB were 0.27 and 0.61, which were relatively low compared with mammals. Relatively high concentrations of p,p'-DDE (68.4-449 ng/g ww) were detected in 10 of total 11 samples, which would cause the feminization of Chinese sturgeons during embryonic development. It was found that lipid-corrected concentrations of HHCB, AHTN, p,p'-DDE, and p,p'-DDD increased with age in female sturgeon, of which the trends were similar to those in fishes and different from those in mammals.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wan</LastName><ForeName>Yi</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>College of Environmental Sciences, Peking University, Beijing, 100871, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wei</LastName><ForeName>Qiwei</ForeName><Initials>Q</Initials></Author><Author ValidYN="Y"><LastName>Hu</LastName><ForeName>Jianying</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Jin</LastName><ForeName>Xiaohui</ForeName><Initials>X</Initials></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Zhaobin</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Zhen</LastName><ForeName>Huajun</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Liu</LastName><ForeName>Jianyi</ForeName><Initials>J</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Environ Sci Technol</MedlineTA><NlmUniqueID>0213155</NlmUniqueID><ISSNLinking>0013-936X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001578">Benzopyrans</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010476">Perfume</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013764">Tetrahydronaphthalenes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014874">Water Pollutants, Chemical</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014992">Xylenes</NameOfSubstance></Chemical><Chemical><RegistryNumber>14170060AT</RegistryNumber><NameOfSubstance UI="C033119">galaxolide</NameOfSubstance></Chemical><Chemical><RegistryNumber>1ZAO16GU5K</RegistryNumber><NameOfSubstance UI="C031447">musk xylene</NameOfSubstance></Chemical><Chemical><RegistryNumber>21145-77-7</RegistryNumber><NameOfSubstance UI="C033116">acetyl methyl tetramethyl tetralin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000273" MajorTopicYN="N">Adipose Tissue</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001578" MajorTopicYN="N">Benzopyrans</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002681" MajorTopicYN="N">China</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004784" MajorTopicYN="N">Environmental Monitoring</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="Y">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005399" MajorTopicYN="N">Fishes</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008401" MajorTopicYN="N">Gas Chromatography-Mass Spectrometry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010476" MajorTopicYN="N">Perfume</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013764" MajorTopicYN="N">Tetrahydronaphthalenes</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014018" MajorTopicYN="N">Tissue Distribution</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014874" MajorTopicYN="N">Water Pollutants, Chemical</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014992" MajorTopicYN="N">Xylenes</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName><QualifierName UI="Q000493" MajorTopicYN="Y">pharmacokinetics</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>2</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>3</Month><Day>10</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>2</Month><Day>22</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">17310702</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><region><li>Pékin</li></region><settlement><li>Pékin</li></settlement><orgName><li>Université de Pékin</li></orgName></list><tree><noCountry><name sortKey="Hu, Jianying" sort="Hu, Jianying" uniqKey="Hu J" first="Jianying" last="Hu">Jianying Hu</name><name sortKey="Jin, Xiaohui" sort="Jin, Xiaohui" uniqKey="Jin X" first="Xiaohui" last="Jin">Xiaohui Jin</name><name sortKey="Liu, Jianyi" sort="Liu, Jianyi" uniqKey="Liu J" first="Jianyi" last="Liu">Jianyi Liu</name><name sortKey="Wei, Qiwei" sort="Wei, Qiwei" uniqKey="Wei Q" first="Qiwei" last="Wei">Qiwei Wei</name><name sortKey="Zhang, Zhaobin" sort="Zhang, Zhaobin" uniqKey="Zhang Z" first="Zhaobin" last="Zhang">Zhaobin Zhang</name><name sortKey="Zhen, Huajun" sort="Zhen, Huajun" uniqKey="Zhen H" first="Huajun" last="Zhen">Huajun Zhen</name></noCountry><country name="République populaire de Chine"><region name="Pékin"><name sortKey="Wan, Yi" sort="Wan, Yi" uniqKey="Wan Y" first="Yi" last="Wan">Yi Wan</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000463 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 000463 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:17310702
|texte= Levels, tissue distribution, and age-related accumulation of synthetic musk fragrances in Chinese sturgeon (Acipenser sinensis): comparison to organochlorines.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:17310702" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a EsturgeonV1
| This area was generated with Dilib version V0.6.27. |  |