EsturgeonV1, PascalFrancis, Corpus, bibRecord, 000489

Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran

Identifieur interne : 000489 ( PascalFrancis/Corpus ); précédent : 000488; suivant : 000490

Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran

Auteurs : V. P. Palace ; T. A. Dick ; S. B. Brown ; C. L. Baron ; J. F. Klaverkamp

Source :

Aquatic toxicology [ 0166-445X ] ; 1996.

RBID : Pascal:96-0426818

Descripteurs français

Pascal (Inist)
- Pollution eau, Effluent, Papeterie, Accumulation biologique, Composé lipophile, Toxicité, Stress oxydatif, Activité enzymatique, Métabolisme, Antioxydant, Acipenser fulvescens, Acipenseridae, 2,3,7,8-tetrachlorodibenzofuran.

English descriptors

KwdEn :
- Antioxidant, Biological accumulation, Effluent, Enzymatic activity, Lipophilic compound, Metabolism, Oxidative stress, Paper mill, Toxicity, Water pollution.

Abstract

Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [³H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg^-1 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A11	`01`	`1`		`@1 PALACE (V. P.)`
A11	`02`	`1`		`@1 DICK (T. A.)`
A11	`03`	`1`		`@1 BROWN (S. B.)`
A11	`04`	`1`		`@1 BARON (C. L.)`
A11	`05`	`1`		`@1 KLAVERKAMP (J. F.)`
A14	`01`			`@1 University of Manitoba @2 Winnipeg, Man. R3T 2N6 @3 CAN @Z 1 aut. @Z 2 aut. @Z 5 aut.`
A14	`02`			`@1 Department of Fisheries and Oceans, Freshwater Institute @2 Winnipeg, Man. R3T 2N6 @3 CAN @Z 3 aut. @Z 4 aut. @Z 5 aut.`
A20				`@1 79-92`
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A43	`01`			`@1 INIST @2 18841 @5 354000063881600002`
A44				`@0 9000 @1 © 1996 Elsevier Science B.V. All rights reserved.`
A47	`01`	`1`		`@0 96-0426818`
A60				`@1 P`
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A64	`01`	`1`		`@0 Aquatic toxicology`
A66	`01`			`@0 NLD`
C01	`01`		`ENG`	@0 Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [³H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg^-1 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.
C02	`01`	`X`		`@0 002A14D05H1`
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C03	`01`	`X`	`ENG`	`@0 Water pollution @5 01`
C03	`01`	`X`	`GER`	`@0 Wasserverschmutzung @5 01`
C03	`01`	`X`	`SPA`	`@0 Contaminación agua @5 01`
C03	`02`	`X`	`FRE`	`@0 Effluent @5 02`
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C03	`02`	`X`	`SPA`	`@0 Efluente @5 02`
C03	`03`	`X`	`FRE`	`@0 Papeterie @5 03`
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C03	`04`	`X`	`FRE`	`@0 Accumulation biologique @5 04`
C03	`04`	`X`	`ENG`	`@0 Biological accumulation @5 04`
C03	`04`	`X`	`SPA`	`@0 Acumulación biológica @5 04`
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C03	`05`	`X`	`ENG`	`@0 Lipophilic compound @5 05`
C03	`05`	`X`	`SPA`	`@0 Compuesto lipófilo @5 05`
C03	`06`	`X`	`FRE`	`@0 Toxicité @5 06`
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C03	`06`	`X`	`SPA`	`@0 Toxicidad @5 06`
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C03	`08`	`X`	`FRE`	`@0 Activité enzymatique @5 08`
C03	`08`	`X`	`ENG`	`@0 Enzymatic activity @5 08`
C03	`08`	`X`	`SPA`	`@0 Actividad enzimática @5 08`
C03	`09`	`X`	`FRE`	`@0 Métabolisme @5 09`
C03	`09`	`X`	`ENG`	`@0 Metabolism @5 09`
C03	`09`	`X`	`SPA`	`@0 Metabolismo @5 09`
C03	`10`	`X`	`FRE`	`@0 Antioxydant @5 10`
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C03	`10`	`X`	`SPA`	`@0 Antioxidante @5 10`
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N21				`@1 295`

Format Inist (serveur)

NO :	PASCAL 96-0426818 Elsevier
ET :	Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran
AU :	PALACE (V. P.); DICK (T. A.); BROWN (S. B.); BARON (C. L.); KLAVERKAMP (J. F.)
AF :	University of Manitoba/Winnipeg, Man. R3T 2N6/Canada (1 aut., 2 aut., 5 aut.); Department of Fisheries and Oceans, Freshwater Institute/Winnipeg, Man. R3T 2N6/Canada (3 aut., 4 aut., 5 aut.)
DT :	Publication en série; Niveau analytique
SO :	Aquatic toxicology; ISSN 0166-445X; Coden AQTODG; Pays-Bas; Da. 1996; Vol. 35; No. 2; Pp. 79-92; Abs. anglais
LA :	Anglais
EA :	Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [³H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg^-1 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.
CC :	002A14D05H1
FD :	Pollution eau; Effluent; Papeterie; Accumulation biologique; Composé lipophile; Toxicité; Stress oxydatif; Activité enzymatique; Métabolisme; Antioxydant; Acipenser fulvescens; Acipenseridae; 2,3,7,8-tetrachlorodibenzofuran
FG :	Milieu eau douce; Pisces; Vertebrata
ED :	Water pollution; Effluent; Paper mill; Biological accumulation; Lipophilic compound; Toxicity; Oxidative stress; Enzymatic activity; Metabolism; Antioxidant
EG :	Freshwater environment; Pisces; Vertebrata
GD :	Wasserverschmutzung; Giftigkeit
SD :	Contaminación agua; Efluente; Papelera; Acumulación biológica; Compuesto lipófilo; Toxicidad; Stress oxidativo; Actividad enzimática; Metabolismo; Antioxidante
LO :	INIST-18841.354000063881600002
ID :	96-0426818

Links to Exploration step

Pascal:96-0426818

Le document en format XML

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<front><div type="abstract" xml:lang="en">Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [<sup>3</sup>
H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg<sup>-1</sup>
 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.</div>
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<fC01 i1="01" l="ENG"><s0>Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [<sup>3</sup>
H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg<sup>-1</sup>
 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.</s0>
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<fC03 i1="01" i2="X" l="FRE"><s0>Pollution eau</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Water pollution</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="GER"><s0>Wasserverschmutzung</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Contaminación agua</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Effluent</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Effluent</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Efluente</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Papeterie</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Paper mill</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Papelera</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Accumulation biologique</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Biological accumulation</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Acumulación biológica</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Composé lipophile</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Lipophilic compound</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Compuesto lipófilo</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Toxicité</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Toxicity</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="GER"><s0>Giftigkeit</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Toxicidad</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Stress oxydatif</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Oxidative stress</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Stress oxidativo</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Activité enzymatique</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Enzymatic activity</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Actividad enzimática</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Métabolisme</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Metabolism</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Metabolismo</s0>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Antioxydant</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Antioxidant</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Antioxidante</s0>
<s5>10</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Acipenser fulvescens</s0>
<s2>NS</s2>
<s4>INC</s4>
<s5>65</s5>
</fC03>
<fC03 i1="12" i2="X" l="FRE"><s0>Acipenseridae</s0>
<s2>NS</s2>
<s4>INC</s4>
<s5>71</s5>
</fC03>
<fC03 i1="13" i2="X" l="FRE"><s0>2,3,7,8-tetrachlorodibenzofuran</s0>
<s2>FF</s2>
<s4>INC</s4>
<s5>80</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Milieu eau douce</s0>
<s5>13</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Freshwater environment</s0>
<s5>13</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Medio agua dulce</s0>
<s5>13</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Pisces</s0>
<s2>NS</s2>
<s5>58</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Pisces</s0>
<s2>NS</s2>
<s5>58</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Pisces</s0>
<s2>NS</s2>
<s5>58</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Vertebrata</s0>
<s2>NS</s2>
</fC07>
<fN21><s1>295</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 96-0426818 Elsevier</NO>
<ET>Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran</ET>
<AU>PALACE (V. P.); DICK (T. A.); BROWN (S. B.); BARON (C. L.); KLAVERKAMP (J. F.)</AU>
<AF>University of Manitoba/Winnipeg, Man. R3T 2N6/Canada (1 aut., 2 aut., 5 aut.); Department of Fisheries and Oceans, Freshwater Institute/Winnipeg, Man. R3T 2N6/Canada (3 aut., 4 aut., 5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Aquatic toxicology; ISSN 0166-445X; Coden AQTODG; Pays-Bas; Da. 1996; Vol. 35; No. 2; Pp. 79-92; Abs. anglais</SO>
<LA>Anglais</LA>
<EA>Copyright (c) 1996 Elsevier Science B.V. All rights reserved. Juvenile lake sturgeon were orally dosed with gelatin containing nominal concentrations of 0, 0.16 or 1.6 ng [<sup>3</sup>
H]-2,3,7,8-tetrachlorodibenzofuran (TCDF) kg<sup>-1</sup>
 fish weight. Liver, kidney and blood were collected 10 and 27 days after exposure. Phase I mixed-function oxidase (MFO) and Phase II (glucuronyltransferase) enzyme activities were determined in liver. Concentrations of non-enzymatic (tocopherol, retinoids) and enzymatic (superoxide dismutase, catalase, glutathione peroxidase) antioxidant parameters were also quantified in liver and kidney. TCDF concentrations were elevated in liver and kidney of both dose groups at 10 and 27 days. Lower tissue concentrations of TCDF at 27 days, compared with 10 day exposures, as well as the presence of polar metabolites in bile, may indicate rapid metabolism and clearance of the contaminant. MFO enzyme activity, measured as ethoxyresorufin-O-de-ethylase (EROD), was induced in liver with activity at the two sample periods reflecting the TCDF concentrations. Greater concentrations of hepatic lipid peroxides in both dose groups, indicate that oxidative stress was produced by contaminant exposure and/or induced metabolism enzyme activity.</EA>
<CC>002A14D05H1</CC>
<FD>Pollution eau; Effluent; Papeterie; Accumulation biologique; Composé lipophile; Toxicité; Stress oxydatif; Activité enzymatique; Métabolisme; Antioxydant; Acipenser fulvescens; Acipenseridae; 2,3,7,8-tetrachlorodibenzofuran</FD>
<FG>Milieu eau douce; Pisces; Vertebrata</FG>
<ED>Water pollution; Effluent; Paper mill; Biological accumulation; Lipophilic compound; Toxicity; Oxidative stress; Enzymatic activity; Metabolism; Antioxidant</ED>
<EG>Freshwater environment; Pisces; Vertebrata</EG>
<GD>Wasserverschmutzung; Giftigkeit</GD>
<SD>Contaminación agua; Efluente; Papelera; Acumulación biológica; Compuesto lipófilo; Toxicidad; Stress oxidativo; Actividad enzimática; Metabolismo; Antioxidante</SD>
<LO>INIST-18841.354000063881600002</LO>
<ID>96-0426818</ID>
</server>
</inist>
</record>

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Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran

Oxidative stress in Lake Sturgeon (Acipenser fulvescens) orally exposed to 2,3,7,8-tetrachlorodibenzofuran

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