Identification of sturgeon IgD bridges the evolutionary gap between elasmobranchs and teleosts.
Identifieur interne : 000504 ( Ncbi/Checkpoint ); précédent : 000503; suivant : 000505Identification of sturgeon IgD bridges the evolutionary gap between elasmobranchs and teleosts.
Auteurs : Lin Zhu [République populaire de Chine] ; Zhenxin Yan ; Mengyang Feng ; Dezhi Peng ; Ying Guo ; Xiaoxiang Hu ; Liming Ren ; Yi SunSource :
- Developmental and comparative immunology [ 1879-0089 ] ; 2014.
English descriptors
- KwdEn :
- Amino Acid Sequence, Animals, Base Sequence, Biological Evolution, Elasmobranchii (genetics), Elasmobranchii (immunology), Gene Expression Profiling, Genetic Variation, Immunoglobulin D (genetics), Immunoglobulin D (immunology), Immunoglobulin Heavy Chains (genetics), Immunoglobulin M (genetics), Immunoglobulin M (immunology), Immunoglobulins (deficiency), Immunoglobulins (genetics), Phylogeny, RNA Splicing, Sequence Alignment, Sequence Analysis, DNA, Transcriptome (genetics).
- MESH :
- chemical , deficiency : Immunoglobulins.
- chemical , genetics : Immunoglobulin D, Immunoglobulin Heavy Chains, Immunoglobulin M, Immunoglobulins.
- genetics : Elasmobranchii, Transcriptome.
- immunology : Elasmobranchii, Immunoglobulin D, Immunoglobulin M.
- Amino Acid Sequence, Animals, Base Sequence, Biological Evolution, Gene Expression Profiling, Genetic Variation, Phylogeny, RNA Splicing, Sequence Alignment, Sequence Analysis, DNA.
Abstract
IgD has been found in almost all jawed vertebrates, including cartilaginous and teleost fish. However, IgD is missing in acipenseriformes, a branch that is evolutionarily positioned between elasmobranchs and teleost fish. Here, by analyzing transcriptome data, we identified a transcriptionally active IgD-encoding gene in the Siberian sturgeon (Acipenser baerii). Phylogenetic analysis indicated that it is orthologous to mammalian IgD and closely related to the IgD of other fish. The lengths of sturgeon membrane-bound IgD transcripts ranged from 1.2kb to 6.2kb, encoding 3-19 CH domains. As in teleosts, the first CH domain of the sturgeon IgD transcript is also derived from μCH1 by RNA splicing. However, the variable region of the expressed sturgeon IgD shows limited V(D)J usage. In addition to IgD, three IgM variants were also identified in this species, whereas no IgT/Z-encoding genes were observed. This study bridges the gap in Ig evolution between elasmobranchs and teleosts and provides significant insight into the early evolution of immunoglobulins.
DOI: 10.1016/j.dci.2013.08.020
PubMed: 24001581
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000211
- to stream PubMed, to step Curation: 000211
- to stream PubMed, to step Checkpoint: 000211
- to stream Ncbi, to step Merge: 000504
- to stream Ncbi, to step Curation: 000504
Links to Exploration step
pubmed:24001581Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Identification of sturgeon IgD bridges the evolutionary gap between elasmobranchs and teleosts.</title><author><name sortKey="Zhu, Lin" sort="Zhu, Lin" uniqKey="Zhu L" first="Lin" last="Zhu">Lin Zhu</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Agrobiotechnology, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing 100193, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Agrobiotechnology, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing 100193</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yan, Zhenxin" sort="Yan, Zhenxin" uniqKey="Yan Z" first="Zhenxin" last="Yan">Zhenxin Yan</name></author><author><name sortKey="Feng, Mengyang" sort="Feng, Mengyang" uniqKey="Feng M" first="Mengyang" last="Feng">Mengyang Feng</name></author><author><name sortKey="Peng, Dezhi" sort="Peng, Dezhi" uniqKey="Peng D" first="Dezhi" last="Peng">Dezhi Peng</name></author><author><name sortKey="Guo, Ying" sort="Guo, Ying" uniqKey="Guo Y" first="Ying" last="Guo">Ying Guo</name></author><author><name sortKey="Hu, Xiaoxiang" sort="Hu, Xiaoxiang" uniqKey="Hu X" first="Xiaoxiang" last="Hu">Xiaoxiang Hu</name></author><author><name sortKey="Ren, Liming" sort="Ren, Liming" uniqKey="Ren L" first="Liming" last="Ren">Liming Ren</name></author><author><name sortKey="Sun, Yi" sort="Sun, Yi" uniqKey="Sun Y" first="Yi" last="Sun">Yi Sun</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:24001581</idno><idno type="pmid">24001581</idno><idno type="doi">10.1016/j.dci.2013.08.020</idno><idno type="wicri:Area/PubMed/Corpus">000211</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000211</idno><idno type="wicri:Area/PubMed/Curation">000211</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000211</idno><idno type="wicri:Area/PubMed/Checkpoint">000211</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000211</idno><idno type="wicri:Area/Ncbi/Merge">000504</idno><idno type="wicri:Area/Ncbi/Curation">000504</idno><idno type="wicri:Area/Ncbi/Checkpoint">000504</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Identification of sturgeon IgD bridges the evolutionary gap between elasmobranchs and teleosts.</title><author><name sortKey="Zhu, Lin" sort="Zhu, Lin" uniqKey="Zhu L" first="Lin" last="Zhu">Lin Zhu</name><affiliation wicri:level="1"><nlm:affiliation>State Key Laboratory of Agrobiotechnology, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing 100193, PR China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>State Key Laboratory of Agrobiotechnology, College of Biological Sciences, National Engineering Laboratory for Animal Breeding, China Agricultural University, Beijing 100193</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yan, Zhenxin" sort="Yan, Zhenxin" uniqKey="Yan Z" first="Zhenxin" last="Yan">Zhenxin Yan</name></author><author><name sortKey="Feng, Mengyang" sort="Feng, Mengyang" uniqKey="Feng M" first="Mengyang" last="Feng">Mengyang Feng</name></author><author><name sortKey="Peng, Dezhi" sort="Peng, Dezhi" uniqKey="Peng D" first="Dezhi" last="Peng">Dezhi Peng</name></author><author><name sortKey="Guo, Ying" sort="Guo, Ying" uniqKey="Guo Y" first="Ying" last="Guo">Ying Guo</name></author><author><name sortKey="Hu, Xiaoxiang" sort="Hu, Xiaoxiang" uniqKey="Hu X" first="Xiaoxiang" last="Hu">Xiaoxiang Hu</name></author><author><name sortKey="Ren, Liming" sort="Ren, Liming" uniqKey="Ren L" first="Liming" last="Ren">Liming Ren</name></author><author><name sortKey="Sun, Yi" sort="Sun, Yi" uniqKey="Sun Y" first="Yi" last="Sun">Yi Sun</name></author></analytic><series><title level="j">Developmental and comparative immunology</title><idno type="eISSN">1879-0089</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Amino Acid Sequence</term><term>Animals</term><term>Base Sequence</term><term>Biological Evolution</term><term>Elasmobranchii (genetics)</term><term>Elasmobranchii (immunology)</term><term>Gene Expression Profiling</term><term>Genetic Variation</term><term>Immunoglobulin D (genetics)</term><term>Immunoglobulin D (immunology)</term><term>Immunoglobulin Heavy Chains (genetics)</term><term>Immunoglobulin M (genetics)</term><term>Immunoglobulin M (immunology)</term><term>Immunoglobulins (deficiency)</term><term>Immunoglobulins (genetics)</term><term>Phylogeny</term><term>RNA Splicing</term><term>Sequence Alignment</term><term>Sequence Analysis, DNA</term><term>Transcriptome (genetics)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="deficiency" xml:lang="en"><term>Immunoglobulins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Immunoglobulin D</term><term>Immunoglobulin Heavy Chains</term><term>Immunoglobulin M</term><term>Immunoglobulins</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Elasmobranchii</term><term>Transcriptome</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elasmobranchii</term><term>Immunoglobulin D</term><term>Immunoglobulin M</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term><term>Animals</term><term>Base Sequence</term><term>Biological Evolution</term><term>Gene Expression Profiling</term><term>Genetic Variation</term><term>Phylogeny</term><term>RNA Splicing</term><term>Sequence Alignment</term><term>Sequence Analysis, DNA</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">IgD has been found in almost all jawed vertebrates, including cartilaginous and teleost fish. However, IgD is missing in acipenseriformes, a branch that is evolutionarily positioned between elasmobranchs and teleost fish. Here, by analyzing transcriptome data, we identified a transcriptionally active IgD-encoding gene in the Siberian sturgeon (Acipenser baerii). Phylogenetic analysis indicated that it is orthologous to mammalian IgD and closely related to the IgD of other fish. The lengths of sturgeon membrane-bound IgD transcripts ranged from 1.2kb to 6.2kb, encoding 3-19 CH domains. As in teleosts, the first CH domain of the sturgeon IgD transcript is also derived from μCH1 by RNA splicing. However, the variable region of the expressed sturgeon IgD shows limited V(D)J usage. In addition to IgD, three IgM variants were also identified in this species, whereas no IgT/Z-encoding genes were observed. This study bridges the gap in Ig evolution between elasmobranchs and teleosts and provides significant insight into the early evolution of immunoglobulins.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><noCountry><name sortKey="Feng, Mengyang" sort="Feng, Mengyang" uniqKey="Feng M" first="Mengyang" last="Feng">Mengyang Feng</name><name sortKey="Guo, Ying" sort="Guo, Ying" uniqKey="Guo Y" first="Ying" last="Guo">Ying Guo</name><name sortKey="Hu, Xiaoxiang" sort="Hu, Xiaoxiang" uniqKey="Hu X" first="Xiaoxiang" last="Hu">Xiaoxiang Hu</name><name sortKey="Peng, Dezhi" sort="Peng, Dezhi" uniqKey="Peng D" first="Dezhi" last="Peng">Dezhi Peng</name><name sortKey="Ren, Liming" sort="Ren, Liming" uniqKey="Ren L" first="Liming" last="Ren">Liming Ren</name><name sortKey="Sun, Yi" sort="Sun, Yi" uniqKey="Sun Y" first="Yi" last="Sun">Yi Sun</name><name sortKey="Yan, Zhenxin" sort="Yan, Zhenxin" uniqKey="Yan Z" first="Zhenxin" last="Yan">Zhenxin Yan</name></noCountry><country name="République populaire de Chine"><noRegion><name sortKey="Zhu, Lin" sort="Zhu, Lin" uniqKey="Zhu L" first="Lin" last="Zhu">Lin Zhu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000504 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 000504 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= pubmed:24001581
|texte= Identification of sturgeon IgD bridges the evolutionary gap between elasmobranchs and teleosts.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:24001581" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a EsturgeonV1
| This area was generated with Dilib version V0.6.27. |  |