Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout
Identifieur interne : 001B73 ( Main/Merge ); précédent : 001B72; suivant : 001B74Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout
Auteurs : J. P. Cravedi [France] ; A. Paris [France] ; E. Perdu-Durand [France] ; P. Prunet [France]Source :
- Fish Physiology and Biochemistry [ 0920-1742 ] ; 1995-08-01.
Abstract
Abstract: The effect of GH treatment on hepatic cytochrome P450 content, aryl hydrocarbon hydroxylase (AHH), aminopyrine-N-demethylase (AND), testosterone hydroxylase, testosterone 5α- and 5β-reductase, UDP-glucuronyl transferase (UDPGT) and glutathione S-transferase (GST) activities in immature rainbow trout were investigated. Hepatic cytochrome P450 content, AHH and GST activities were measured in both GH implanted and GH injected animals whereas other activities were assayed in GH implanted trout only. GH implants significantly decreased cytochrome P450 content at 15 days compared to the control but no significant effect was observed at 15 or 30 d when GH was injected biweekly. In both cases, AHH activity was significantly decreased by GH treatment compared to the control whereas GST remained unchanged. Compared to the control, GH implanted fish exhibited a pronounced inhibition of AND, a decreased 6β and 16β-testosterone hydroxylation, an inhibition of UDPGT with testosterone as substrate and an enhanced 17β-testosterone oxidation.
Url:
DOI: 10.1007/BF00004064
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000912
- to stream Istex, to step Curation: 000910
- to stream Istex, to step Checkpoint: 001025
Links to Exploration step
ISTEX:CE57BD9287F43AD2108053E30CA006A89426B68ELe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout</title><author><name sortKey="Cravedi, J P" sort="Cravedi, J P" uniqKey="Cravedi J" first="J. P." last="Cravedi">J. P. Cravedi</name></author><author><name sortKey="Paris, A" sort="Paris, A" uniqKey="Paris A" first="A." last="Paris">A. Paris</name></author><author><name sortKey="Perdu Durand, E" sort="Perdu Durand, E" uniqKey="Perdu Durand E" first="E." last="Perdu-Durand">E. Perdu-Durand</name></author><author><name sortKey="Prunet, P" sort="Prunet, P" uniqKey="Prunet P" first="P." last="Prunet">P. Prunet</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:CE57BD9287F43AD2108053E30CA006A89426B68E</idno><date when="1995" year="1995">1995</date><idno type="doi">10.1007/BF00004064</idno><idno type="url">https://api.istex.fr/document/CE57BD9287F43AD2108053E30CA006A89426B68E/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000912</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000912</idno><idno type="wicri:Area/Istex/Curation">000910</idno><idno type="wicri:Area/Istex/Checkpoint">001025</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">001025</idno><idno type="wicri:doubleKey">0920-1742:1995:Cravedi J:influence:of:growth</idno><idno type="wicri:Area/Main/Merge">001B73</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout</title><author><name sortKey="Cravedi, J P" sort="Cravedi, J P" uniqKey="Cravedi J" first="J. P." last="Cravedi">J. P. Cravedi</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INRA, Laboratoire des Xénobiotiques, chemin de Tournefeuille, B.P., 3 180, 31931, Toulouse Cédex</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Midi-Pyrénées</region><settlement type="city">Toulouse Cédex</settlement></placeName></affiliation></author><author><name sortKey="Paris, A" sort="Paris, A" uniqKey="Paris A" first="A." last="Paris">A. Paris</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INRA, Laboratoire des Xénobiotiques, chemin de Tournefeuille, B.P., 3 180, 31931, Toulouse Cédex</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Midi-Pyrénées</region><settlement type="city">Toulouse Cédex</settlement></placeName></affiliation></author><author><name sortKey="Perdu Durand, E" sort="Perdu Durand, E" uniqKey="Perdu Durand E" first="E." last="Perdu-Durand">E. Perdu-Durand</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INRA, Laboratoire des Xénobiotiques, chemin de Tournefeuille, B.P., 3 180, 31931, Toulouse Cédex</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Midi-Pyrénées</region><settlement type="city">Toulouse Cédex</settlement></placeName></affiliation></author><author><name sortKey="Prunet, P" sort="Prunet, P" uniqKey="Prunet P" first="P." last="Prunet">P. Prunet</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>INRA, Laboratoire de Physiologie des Poissons, Campus de Beaulieu, 35042, Rennes</wicri:regionArea><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Fish Physiology and Biochemistry</title><title level="j" type="abbrev">Fish Physiol Biochem</title><idno type="ISSN">0920-1742</idno><idno type="eISSN">1573-5168</idno><imprint><publisher>Kluwer Academic Publishers</publisher><pubPlace>Dordrecht</pubPlace><date type="published" when="1995-08-01">1995-08-01</date><biblScope unit="volume">14</biblScope><biblScope unit="issue">4</biblScope><biblScope unit="page" from="259">259</biblScope><biblScope unit="page" to="266">266</biblScope></imprint><idno type="ISSN">0920-1742</idno></series><idno type="istex">CE57BD9287F43AD2108053E30CA006A89426B68E</idno><idno type="DOI">10.1007/BF00004064</idno><idno type="ArticleID">BF00004064</idno><idno type="ArticleID">Art1</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0920-1742</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: The effect of GH treatment on hepatic cytochrome P450 content, aryl hydrocarbon hydroxylase (AHH), aminopyrine-N-demethylase (AND), testosterone hydroxylase, testosterone 5α- and 5β-reductase, UDP-glucuronyl transferase (UDPGT) and glutathione S-transferase (GST) activities in immature rainbow trout were investigated. Hepatic cytochrome P450 content, AHH and GST activities were measured in both GH implanted and GH injected animals whereas other activities were assayed in GH implanted trout only. GH implants significantly decreased cytochrome P450 content at 15 days compared to the control but no significant effect was observed at 15 or 30 d when GH was injected biweekly. In both cases, AHH activity was significantly decreased by GH treatment compared to the control whereas GST remained unchanged. Compared to the control, GH implanted fish exhibited a pronounced inhibition of AND, a decreased 6β and 16β-testosterone hydroxylation, an inhibition of UDPGT with testosterone as substrate and an enhanced 17β-testosterone oxidation.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001B73 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 001B73 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:CE57BD9287F43AD2108053E30CA006A89426B68E
|texte= Influence of growth hormone on the hepatic mixed function oxidase and transferase systems of rainbow trout
}}
| This area was generated with Dilib version V0.6.27. |  |