Immunhistochemical Demonstration of Lumbar Intervertebral Disc Innervation in the Dog
Identifieur interne : 000F30 ( Main/Merge ); précédent : 000F29; suivant : 000F31Immunhistochemical Demonstration of Lumbar Intervertebral Disc Innervation in the Dog
Auteurs : S. Willenegger [Suisse] ; A. E. Friess [Suisse] ; M. H. Stoffel [Suisse]Source :
- Anatomia, Histologia, Embryologia [ 0340-2096 ] ; 2005-12.
Abstract
Low back pain is a common ailment in dogs, particularly in specific breeds as for instance the German shepherd dog. A number of structures such as facet joint capsules, ligaments, dorsal root ganglia, periosteum, vertebral endplate, and meninges have been associated with this condition. However, in a substantial proportion of all cases, the origin of pain remains obscure. A further structure often being involved in vertebral column disorders is the intervertebral disc. However, the presence of nerves is a precondition for pain sensation and, consequently, structures lacking sensory innervation can be left out of consideration as a cause for low back pain. Nerve fibres have been demonstrated at the periphery of intervertebral discs in man, rabbit and rat. With regard to the dog, however, extent of intervertebral disc innervation still is disputed. The goal of the present study, therefore, was to assess previous findings based on silver impregnation. Protein gene product (PGP) 9.5 was used as a marker for immunohistochemical examination of serial transversal and sagittal paraffin sections of lumbar discs from adult dogs. This technique revealed nerve fibres to be confined to the periphery of the intervertebral discs. Thus, even limited pathological processes affecting the outer layers of the intervertebral disc are prone to cause low back pain.
Url:
DOI: 10.1111/j.1439-0264.2005.00669_131.x
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001525
- to stream Istex, to step Curation: 001523
- to stream Istex, to step Checkpoint: 000795
Links to Exploration step
ISTEX:F0E55C751F9B7AF6071CC9A2CB046288F84FF876Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunhistochemical Demonstration of Lumbar Intervertebral Disc Innervation in the Dog</title><author><name sortKey="Willenegger, S" sort="Willenegger, S" uniqKey="Willenegger S" first="S." last="Willenegger">S. Willenegger</name></author><author><name sortKey="Friess, A E" sort="Friess, A E" uniqKey="Friess A" first="A. E." last="Friess">A. E. Friess</name></author><author><name sortKey="Stoffel, M H" sort="Stoffel, M H" uniqKey="Stoffel M" first="M. H." last="Stoffel">M. H. Stoffel</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F0E55C751F9B7AF6071CC9A2CB046288F84FF876</idno><date when="2005" year="2005">2005</date><idno type="doi">10.1111/j.1439-0264.2005.00669_131.x</idno><idno type="url">https://api.istex.fr/document/F0E55C751F9B7AF6071CC9A2CB046288F84FF876/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001525</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001525</idno><idno type="wicri:Area/Istex/Curation">001523</idno><idno type="wicri:Area/Istex/Checkpoint">000795</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000795</idno><idno type="wicri:doubleKey">0340-2096:2005:Willenegger S:immunhistochemical:demonstration:of</idno><idno type="wicri:Area/Main/Merge">000F30</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Immunhistochemical Demonstration of Lumbar Intervertebral Disc Innervation in the Dog</title><author><name sortKey="Willenegger, S" sort="Willenegger, S" uniqKey="Willenegger S" first="S." last="Willenegger">S. Willenegger</name><affiliation wicri:level="3"><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Veterinary Anatomy, University of Berne Veterinary School, Berne</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Friess, A E" sort="Friess, A E" uniqKey="Friess A" first="A. E." last="Friess">A. E. Friess</name><affiliation wicri:level="3"><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Veterinary Anatomy, University of Berne Veterinary School, Berne</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author><author><name sortKey="Stoffel, M H" sort="Stoffel, M H" uniqKey="Stoffel M" first="M. H." last="Stoffel">M. H. Stoffel</name><affiliation wicri:level="3"><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Veterinary Anatomy, University of Berne Veterinary School, Berne</wicri:regionArea><placeName><settlement type="city">Berne</settlement><region type="région" nuts="3">Canton de Berne</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Anatomia, Histologia, Embryologia</title><idno type="ISSN">0340-2096</idno><idno type="eISSN">1439-0264</idno><imprint><publisher>Blackwell Verlag GmbH</publisher><pubPlace>Berlin, Germany</pubPlace><date type="published" when="2005-12">2005-12</date><biblScope unit="volume">34</biblScope><biblScope unit="supplement">s1</biblScope><biblScope unit="page" from="57">57</biblScope><biblScope unit="page" to="57">57</biblScope></imprint><idno type="ISSN">0340-2096</idno></series><idno type="istex">F0E55C751F9B7AF6071CC9A2CB046288F84FF876</idno><idno type="DOI">10.1111/j.1439-0264.2005.00669_131.x</idno><idno type="ArticleID">AHE669_131_131</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0340-2096</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Low back pain is a common ailment in dogs, particularly in specific breeds as for instance the German shepherd dog. A number of structures such as facet joint capsules, ligaments, dorsal root ganglia, periosteum, vertebral endplate, and meninges have been associated with this condition. However, in a substantial proportion of all cases, the origin of pain remains obscure. A further structure often being involved in vertebral column disorders is the intervertebral disc. However, the presence of nerves is a precondition for pain sensation and, consequently, structures lacking sensory innervation can be left out of consideration as a cause for low back pain. Nerve fibres have been demonstrated at the periphery of intervertebral discs in man, rabbit and rat. With regard to the dog, however, extent of intervertebral disc innervation still is disputed. The goal of the present study, therefore, was to assess previous findings based on silver impregnation. Protein gene product (PGP) 9.5 was used as a marker for immunohistochemical examination of serial transversal and sagittal paraffin sections of lumbar discs from adult dogs. This technique revealed nerve fibres to be confined to the periphery of the intervertebral discs. Thus, even limited pathological processes affecting the outer layers of the intervertebral disc are prone to cause low back pain.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F30 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000F30 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:F0E55C751F9B7AF6071CC9A2CB046288F84FF876
|texte= Immunhistochemical Demonstration of Lumbar Intervertebral Disc Innervation in the Dog
}}
| This area was generated with Dilib version V0.6.27. |  |