Effects of plant‐based diets on glucose and amino acid metabolism, leptin, ghrelin and GH‐IGF system regulation in Atlantic salmon (Salmo salar L.)
Identifieur interne : 001748 ( Istex/Corpus ); précédent : 001747; suivant : 001749Effects of plant‐based diets on glucose and amino acid metabolism, leptin, ghrelin and GH‐IGF system regulation in Atlantic salmon (Salmo salar L.)
Auteurs : N. H. Sissener ; G. Hemre ; M. Espe ; M. Sanden ; B. E. Torstensen ; E. M. Hevr YSource :
- Aquaculture Nutrition [ 1353-5773 ] ; 2013-06.
Abstract
To investigate effects on glucose and amino acid (AA) metabolism and neuroendocrine regulation of energy homoeostasis and GH‐IGF system growth regulation, Atlantic salmon were fed high levels of plant protein (PP) and vegetable oil (VO) for 1 year and compared to fish fed intermediate levels or a control diet based on fish meal and fish oil. All plant‐fed groups had reduced liver glucokinase mRNA and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic AAs. There were minor effects on transcription of genes related to leptin, ghrelin and GH‐IGF system. However, muscle growth hormone receptor was elevated in fish fed high PP, probably related to lipolytic action in these fish. Fish fed high levels of both PP and VO simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free AAs, especially proline. These results support interaction effects when both high levels of PP and VO are used together, which needs to be considered in the formulation of aquafeeds.
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DOI: 10.1111/j.1365-2095.2012.00971.x
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Hevr Y</name><affiliation><mods:affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Aquaculture Nutrition</title><title level="j" type="abbrev">Aquacult Nutr</title><idno type="ISSN">1353-5773</idno><idno type="eISSN">1365-2095</idno><imprint><publisher>Blackwell Publishing Ltd</publisher><date type="published" when="2013-06">2013-06</date><biblScope unit="volume">19</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="399">399</biblScope><biblScope unit="page" to="412">412</biblScope></imprint><idno type="ISSN">1353-5773</idno></series><idno type="istex">5A2BB762C7CB3CFC65E4A06E1E14672696013963</idno><idno type="DOI">10.1111/j.1365-2095.2012.00971.x</idno><idno type="ArticleID">ANU971</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1353-5773</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract">To investigate effects on glucose and amino acid (AA) metabolism and neuroendocrine regulation of energy homoeostasis and GH‐IGF system growth regulation, Atlantic salmon were fed high levels of plant protein (PP) and vegetable oil (VO) for 1 year and compared to fish fed intermediate levels or a control diet based on fish meal and fish oil. All plant‐fed groups had reduced liver glucokinase mRNA and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic AAs. There were minor effects on transcription of genes related to leptin, ghrelin and GH‐IGF system. However, muscle growth hormone receptor was elevated in fish fed high PP, probably related to lipolytic action in these fish. Fish fed high levels of both PP and VO simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free AAs, especially proline. 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Torstensen</name><affiliations><json:string>National Institute of Nutrition and Seafood Research, Bergen, Norway</json:string></affiliations></json:item><json:item><name>E.M. Hevrøy</name><affiliations><json:string>National Institute of Nutrition and Seafood Research, Bergen, Norway</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>amino acid</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>GH‐IGF</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ghrelin</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>glucose</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>leptin</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>metabolism</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>plant ingredients</value></json:item></subject><articleId><json:string>ANU971</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>To investigate effects on glucose and amino acid (AA) metabolism and neuroendocrine regulation of energy homoeostasis and GH‐IGF system growth regulation, Atlantic salmon were fed high levels of plant protein (PP) and vegetable oil (VO) for 1 year and compared to fish fed intermediate levels or a control diet based on fish meal and fish oil. All plant‐fed groups had reduced liver glucokinase mRNA and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic AAs. There were minor effects on transcription of genes related to leptin, ghrelin and GH‐IGF system. However, muscle growth hormone receptor was elevated in fish fed high PP, probably related to lipolytic action in these fish. Fish fed high levels of both PP and VO simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free AAs, especially proline. 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All plant‐fed groups had reduced liver glucokinase mRNA and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic AAs. There were minor effects on transcription of genes related to leptin, ghrelin and GH‐IGF system. However, muscle growth hormone receptor was elevated in fish fed high PP, probably related to lipolytic action in these fish. Fish fed high levels of both PP and VO simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free AAs, especially proline. These results support interaction effects when both high levels of PP and VO are used together, which needs to be considered in the formulation of aquafeeds.</p></abstract><textClass><keywords scheme="keyword"><list><head>keywords</head><item><term>amino acid</term></item><item><term>GH‐IGF</term></item><item><term>ghrelin</term></item><item><term>glucose</term></item><item><term>leptin</term></item><item><term>metabolism</term></item><item><term>plant ingredients</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article-category</head><item><term>Original Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-12-13">Received</change><change when="2012-04-16">Registration</change><change when="2012-06-27">Created</change><change when="2013-06">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/5A2BB762C7CB3CFC65E4A06E1E14672696013963/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component type="serialArticle" version="2.0" xml:id="anu971" xml:lang="en"><header><publicationMeta level="product"><doi origin="wiley" registered="yes">10.1111/(ISSN)1365-2095</doi><issn type="print">1353-5773</issn><issn type="electronic">1365-2095</issn><idGroup><id type="product" value="ANU"></id></idGroup><titleGroup><title sort="AQUACULTURE NUTRITION" type="main">Aquaculture Nutrition</title><title type="short">Aquacult Nutr</title></titleGroup></publicationMeta><publicationMeta level="part" position="30"><doi origin="wiley">10.1111/anu.2013.19.issue-3</doi><copyright ownership="publisher">Copyright © 2013 Blackwell Publishing Ltd</copyright><numberingGroup><numbering type="journalVolume" number="19">19</numbering><numbering type="journalIssue">3</numbering></numberingGroup><coverDate startDate="2013-06">June 2013</coverDate></publicationMeta><publicationMeta level="unit" position="170" status="forIssue" type="article"><doi>10.1111/j.1365-2095.2012.00971.x</doi><idGroup><id type="unit" value="ANU971"></id></idGroup><countGroup><count number="14" type="pageTotal"></count></countGroup><titleGroup><title type="articleCategory">Original Article</title><title type="tocHeading1">Original articles</title></titleGroup><copyright ownership="publisher">© 2012 Blackwell Publishing Ltd</copyright><eventGroup><event date="2011-12-13" type="manuscriptReceived"></event><event date="2012-04-16" type="manuscriptAccepted"></event><event agent="SPS" date="2012-06-27" type="xmlCreated"></event><event type="publishedOnlineEarlyUnpaginated" date="2012-06-28"></event><event type="firstOnline" date="2012-06-28"></event><event type="publishedOnlineFinalForm" date="2013-04-29"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-04"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.6.4 mode:FullText" date="2015-10-02"></event></eventGroup><numberingGroup><numbering type="pageFirst">399</numbering><numbering type="pageLast">412</numbering></numberingGroup><correspondenceTo><i>Correspondence: Nini H. Sissener, National Institute of Nutrition and Seafood Research, NIFES, Postboks 2029 Nordnes, 5817 Bergen, Norway. E‐mail</i>: <email>nsi@nifes.no</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ANU.ANU971.pdf"></link></linkGroup></publicationMeta><contentMeta><titleGroup><title type="main">Effects of plant‐based diets on glucose and amino acid metabolism, leptin, ghrelin and <fc>GH</fc>‐<fc>IGF</fc> system regulation in <fc>A</fc>tlantic salmon (<i><fc>S</fc>almo salar </i> <fc>L</fc>.)</title><title type="shortAuthors">N. H. Sissener <i>et al</i>.</title></titleGroup><creators><creator affiliationRef="#anu971-aff-0001" corresponding="yes" creatorRole="author" xml:id="anu971-cr-0001"><personName><givenNames>N.H.</givenNames> <familyName>Sissener</familyName></personName></creator><creator affiliationRef="#anu971-aff-0001" creatorRole="author" xml:id="anu971-cr-0002"><personName><givenNames>G.‐I.</givenNames> <familyName>Hemre</familyName></personName></creator><creator affiliationRef="#anu971-aff-0001" creatorRole="author" xml:id="anu971-cr-0003"><personName><givenNames>M.</givenNames> <familyName>Espe</familyName></personName></creator><creator affiliationRef="#anu971-aff-0001" creatorRole="author" xml:id="anu971-cr-0004"><personName><givenNames>M.</givenNames> <familyName>Sanden</familyName></personName></creator><creator affiliationRef="#anu971-aff-0001" creatorRole="author" xml:id="anu971-cr-0005"><personName><givenNames>B.E.</givenNames> <familyName>Torstensen</familyName></personName></creator><creator affiliationRef="#anu971-aff-0001" creatorRole="author" xml:id="anu971-cr-0006"><personName><givenNames>E.M.</givenNames> <familyName>Hevrøy</familyName></personName></creator></creators><affiliationGroup><affiliation countryCode="NO" type="organization" xml:id="anu971-aff-0001"><orgName>National Institute of Nutrition and Seafood Research</orgName> <address><city>Bergen</city> <country>Norway</country></address></affiliation></affiliationGroup><keywordGroup type="author"><keyword xml:id="anu971-kwd-0001">amino acid</keyword><keyword xml:id="anu971-kwd-0002"><fc>GH</fc>‐<fc>IGF</fc></keyword><keyword xml:id="anu971-kwd-0003">ghrelin</keyword><keyword xml:id="anu971-kwd-0004">glucose</keyword><keyword xml:id="anu971-kwd-0005">leptin</keyword><keyword xml:id="anu971-kwd-0006">metabolism</keyword><keyword xml:id="anu971-kwd-0007">plant ingredients</keyword></keywordGroup><fundingInfo><fundingAgency>AQUAMAX</fundingAgency><fundingNumber>016249‐2</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:id="anu971-abs-0001"><title type="main">Abstract</title><p>To investigate effects on glucose and amino acid (<fc>AA</fc>) metabolism and neuroendocrine regulation of energy homoeostasis and <fc>GH</fc>‐<fc>IGF</fc> system growth regulation, <fc>A</fc>tlantic salmon were fed high levels of plant protein (<fc>PP</fc>) and vegetable oil (<fc>VO</fc>) for 1 year and compared to fish fed intermediate levels or a control diet based on fish meal and fish oil. All plant‐fed groups had reduced liver <i>glucokinase</i> <fc>mRNA</fc> and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic <fc>AA</fc>s. There were minor effects on transcription of genes related to leptin, ghrelin and <fc>GH</fc>‐<fc>IGF</fc> system. However, muscle <i>growth hormone receptor</i> was elevated in fish fed high <fc>PP</fc>, probably related to lipolytic action in these fish. Fish fed high levels of both <fc>PP</fc> and <fc>VO</fc> simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free <fc>AA</fc>s, especially proline. These results support interaction effects when both high levels of <fc>PP</fc> and <fc>VO</fc> are used together, which needs to be considered in the formulation of aquafeeds.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Effects of plant‐based diets on glucose and amino acid metabolism, leptin, ghrelin and GH‐IGF system regulation in Atlantic salmon (Salmo salar L.)</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Effects of plant‐based diets on glucose and amino acid metabolism, leptin, ghrelin and GH‐IGF system regulation in Atlantic salmon (Salmo salar L.)</title></titleInfo><name type="personal"><namePart type="given">N.H.</namePart><namePart type="family">Sissener</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><affiliation>E-mail: nsi@nifes.no</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">G.‐I.</namePart><namePart type="family">Hemre</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Espe</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Sanden</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.E.</namePart><namePart type="family">Torstensen</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">E.M.</namePart><namePart type="family">Hevrøy</namePart><affiliation>National Institute of Nutrition and Seafood Research, Bergen, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Publishing Ltd</publisher><dateIssued encoding="w3cdtf">2013-06</dateIssued><dateCreated encoding="w3cdtf">2012-06-27</dateCreated><dateCaptured encoding="w3cdtf">2011-12-13</dateCaptured><dateValid encoding="w3cdtf">2012-04-16</dateValid><copyrightDate encoding="w3cdtf">2013</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract>To investigate effects on glucose and amino acid (AA) metabolism and neuroendocrine regulation of energy homoeostasis and GH‐IGF system growth regulation, Atlantic salmon were fed high levels of plant protein (PP) and vegetable oil (VO) for 1 year and compared to fish fed intermediate levels or a control diet based on fish meal and fish oil. All plant‐fed groups had reduced liver glucokinase mRNA and increased muscle glycogen compared to the control group. As digestible starch was highest in the control diet, the increased muscle glycogen might be related to other factors such as lower levels of lysine or higher levels of glucogenic AAs. There were minor effects on transcription of genes related to leptin, ghrelin and GH‐IGF system. However, muscle growth hormone receptor was elevated in fish fed high PP, probably related to lipolytic action in these fish. Fish fed high levels of both PP and VO simultaneously had elevated plasma alanine aminotransferase and glucose and of pentose phosphate pathway enzymes. Furthermore, this group had elevated concentrations of some free AAs, especially proline. These results support interaction effects when both high levels of PP and VO are used together, which needs to be considered in the formulation of aquafeeds.</abstract><note type="funding">AQUAMAX - No. 016249‐2; </note><subject><genre>keywords</genre><topic>amino acid</topic><topic>GH‐IGF</topic><topic>ghrelin</topic><topic>glucose</topic><topic>leptin</topic><topic>metabolism</topic><topic>plant ingredients</topic></subject><relatedItem type="host"><titleInfo><title>Aquaculture Nutrition</title></titleInfo><titleInfo type="abbreviated"><title>Aquacult Nutr</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic></subject><identifier type="ISSN">1353-5773</identifier><identifier type="eISSN">1365-2095</identifier><identifier type="DOI">10.1111/(ISSN)1365-2095</identifier><identifier type="PublisherID">ANU</identifier><part><date>2013</date><detail type="volume"><caption>vol.</caption><number>19</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>399</start><end>412</end><total>14</total></extent></part></relatedItem><identifier type="istex">5A2BB762C7CB3CFC65E4A06E1E14672696013963</identifier><identifier type="DOI">10.1111/j.1365-2095.2012.00971.x</identifier><identifier type="ArticleID">ANU971</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2013 Blackwell Publishing Ltd© 2012 Blackwell Publishing Ltd</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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