Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain
Identifieur interne : 001335 ( Istex/Corpus ); précédent : 001334; suivant : 001336Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain
Auteurs : Manuel A. Pombal ; Oscar Marín ; Agustín GonzálezSource :
- Journal of Comparative Neurology [ 0021-9967 ] ; 2001-02-26.
English descriptors
Abstract
The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (Petromyzon marinus and Lampetra fluviatilis), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P
Links to Exploration step
ISTEX:31F9207D96EB8F4B16DCEC6A130EF70606B4510CLe document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title><author><name sortKey="Pombal, Manuel A" sort="Pombal, Manuel A" uniqKey="Pombal M" first="Manuel A." last="Pombal">Manuel A. Pombal</name><affiliation><mods:affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</mods:affiliation></affiliation><affiliation><mods:affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</mods:affiliation></affiliation></author><author><name sortKey="Marin, Oscar" sort="Marin, Oscar" uniqKey="Marin O" first="Oscar" last="Marín">Oscar Marín</name><affiliation><mods:affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</mods:affiliation></affiliation></author><author><name sortKey="Gonzalez, Agustin" sort="Gonzalez, Agustin" uniqKey="Gonzalez A" first="Agustín" last="González">Agustín González</name><affiliation><mods:affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:31F9207D96EB8F4B16DCEC6A130EF70606B4510C</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P</idno><idno type="url">https://api.istex.fr/document/31F9207D96EB8F4B16DCEC6A130EF70606B4510C/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001335</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001335</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title><author><name sortKey="Pombal, Manuel A" sort="Pombal, Manuel A" uniqKey="Pombal M" first="Manuel A." last="Pombal">Manuel A. Pombal</name><affiliation><mods:affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</mods:affiliation></affiliation><affiliation><mods:affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</mods:affiliation></affiliation></author><author><name sortKey="Marin, Oscar" sort="Marin, Oscar" uniqKey="Marin O" first="Oscar" last="Marín">Oscar Marín</name><affiliation><mods:affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</mods:affiliation></affiliation></author><author><name sortKey="Gonzalez, Agustin" sort="Gonzalez, Agustin" uniqKey="Gonzalez A" first="Agustín" last="González">Agustín González</name><affiliation><mods:affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Comparative Neurology</title><title level="j" type="abbrev">J. Comp. Neurol.</title><idno type="ISSN">0021-9967</idno><idno type="eISSN">1096-9861</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2001-02-26">2001-02-26</date><biblScope unit="volume">431</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="105">105</biblScope><biblScope unit="page" to="126">126</biblScope></imprint><idno type="ISSN">0021-9967</idno></series><idno type="istex">31F9207D96EB8F4B16DCEC6A130EF70606B4510C</idno><idno type="DOI">10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P</idno><idno type="ArticleID">CNE1058</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0021-9967</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>acetylcholine</term><term>cyclostomes</term><term>immunohistochemistry</term><term>motor nuclei</term><term>segmentation</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (Petromyzon marinus and Lampetra fluviatilis), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Manuel A. Pombal</name><affiliations><json:string>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</json:string><json:string>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</json:string></affiliations></json:item><json:item><name>Oscar Marín</name><affiliations><json:string>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</json:string></affiliations></json:item><json:item><name>Agustín González</name><affiliations><json:string>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>acetylcholine</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>motor nuclei</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>cyclostomes</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>segmentation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>immunohistochemistry</value></json:item></subject><articleId><json:string>CNE1058</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (Petromyzon marinus and Lampetra fluviatilis), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.</abstract><qualityIndicators><score>8</score><pdfVersion>1.2</pdfVersion><pdfPageSize>594 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>2024</abstractCharCount><pdfWordCount>14726</pdfWordCount><pdfCharCount>92583</pdfCharCount><pdfPageCount>22</pdfPageCount><abstractWordCount>284</abstractWordCount></qualityIndicators><title>Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title><genre><json:string>article</json:string></genre><host><volume>431</volume><publisherId><json:string>CNE</json:string></publisherId><pages><total>22</total><last>126</last><first>105</first></pages><issn><json:string>0021-9967</json:string></issn><issue>1</issue><subject><json:item><value>Research Article</value></json:item></subject><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1096-9861</json:string></eissn><title>Journal of Comparative Neurology</title><doi><json:string>10.1002/(ISSN)1096-9861</json:string></doi></host><categories><wos><json:string>science</json:string><json:string>zoology</json:string><json:string>neurosciences</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>neurology & neurosurgery</json:string></scienceMetrix></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1002/1096-9861(20010226)431:1>105::AID-CNE1058>3.0.CO;2-P</json:string></doi><id>31F9207D96EB8F4B16DCEC6A130EF70606B4510C</id><score>0.02425555</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/31F9207D96EB8F4B16DCEC6A130EF70606B4510C/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/31F9207D96EB8F4B16DCEC6A130EF70606B4510C/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/31F9207D96EB8F4B16DCEC6A130EF70606B4510C/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><availability><p>Copyright © 2001 Wiley‐Liss, Inc.</p></availability><date>2001</date></publicationStmt><notesStmt><note>Xunta de Galicia - No. PGIDT00PXI30112PR;</note><note>Spanish DGINV - No. PM99‐0072;</note><note>Spanish DGICYT - No. PB96‐0606;</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title><author xml:id="author-1"><persName><forename type="first">Manuel A.</forename><surname>Pombal</surname></persName><affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</affiliation><affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</affiliation></author><author xml:id="author-2"><persName><forename type="first">Oscar</forename><surname>Marín</surname></persName><affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</affiliation></author><author xml:id="author-3"><persName><forename type="first">Agustín</forename><surname>González</surname></persName><affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</affiliation></author></analytic><monogr><title level="j">Journal of Comparative Neurology</title><title level="j" type="abbrev">J. Comp. Neurol.</title><idno type="pISSN">0021-9967</idno><idno type="eISSN">1096-9861</idno><idno type="DOI">10.1002/(ISSN)1096-9861</idno><imprint><publisher>John Wiley & Sons, Inc.</publisher><pubPlace>New York</pubPlace><date type="published" when="2001-02-26"></date><biblScope unit="volume">431</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="105">105</biblScope><biblScope unit="page" to="126">126</biblScope></imprint></monogr><idno type="istex">31F9207D96EB8F4B16DCEC6A130EF70606B4510C</idno><idno type="DOI">10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P</idno><idno type="ArticleID">CNE1058</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2001</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (Petromyzon marinus and Lampetra fluviatilis), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>keywords</head><item><term>acetylcholine</term></item><item><term>motor nuclei</term></item><item><term>cyclostomes</term></item><item><term>segmentation</term></item><item><term>immunohistochemistry</term></item></list></keywords></textClass><textClass><keywords scheme="Journal Subject"><list><head>article-category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2000-09-26">Received</change><change when="2000-11-29">Registration</change><change when="2001-02-26">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/31F9207D96EB8F4B16DCEC6A130EF70606B4510C/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>John Wiley & Sons, Inc.</publisherName><publisherLoc>New York</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9861</doi><issn type="print">0021-9967</issn><issn type="electronic">1096-9861</issn><idGroup><id type="product" value="CNE"></id></idGroup><titleGroup><title type="main" xml:lang="en">Journal of Comparative Neurology</title><title type="short">J. Comp. Neurol.</title></titleGroup></publicationMeta><publicationMeta level="part" position="10"><doi origin="wiley" registered="yes">10.1002/1096-9861(20010226)431:1<>1.0.CO;2-S</doi><numberingGroup><numbering type="journalVolume" number="431">431</numbering><numbering type="journalIssue">1</numbering></numberingGroup><coverDate startDate="2001-02-26">26 February 2001</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="1058" status="forIssue"><doi origin="wiley" registered="yes">10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P</doi><idGroup><id type="unit" value="CNE1058"></id></idGroup><countGroup><count type="pageTotal" number="22"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2001 Wiley‐Liss, Inc.</copyright><eventGroup><event type="manuscriptReceived" date="2000-09-26"></event><event type="manuscriptRevised" date="2000-11-29"></event><event type="manuscriptAccepted" date="2000-11-29"></event><event type="firstOnline" date="2001-01-24"></event><event type="publishedOnlineFinalForm" date="2001-01-24"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-03-01"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-15"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-23"></event></eventGroup><numberingGroup><numbering type="pageFirst">105</numbering><numbering type="pageLast">126</numbering></numberingGroup><correspondenceTo>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:CNE.CNE1058.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="8"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="139"></count><count type="wordTotal" number="16787"></count></countGroup><titleGroup><title type="main" xml:lang="en">Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title><title type="short" xml:lang="en">Acetylcholine in the Lamprey Brain</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Manuel A.</givenNames><familyName>Pombal</familyName></personName><contactDetails><email>pombal@uvigo.es</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Oscar</givenNames><familyName>Marín</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af2"><personName><givenNames>Agustín</givenNames><familyName>González</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="ES" type="organization"><unparsedAffiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="ES" type="organization"><unparsedAffiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en" type="author"><keyword xml:id="kwd1">acetylcholine</keyword><keyword xml:id="kwd2">motor nuclei</keyword><keyword xml:id="kwd3">cyclostomes</keyword><keyword xml:id="kwd4">segmentation</keyword><keyword xml:id="kwd5">immunohistochemistry</keyword></keywordGroup><fundingInfo><fundingAgency>Xunta de Galicia</fundingAgency><fundingNumber>PGIDT00PXI30112PR</fundingNumber></fundingInfo><fundingInfo><fundingAgency>Spanish DGINV</fundingAgency><fundingNumber>PM99‐0072</fundingNumber></fundingInfo><fundingInfo><fundingAgency>Spanish DGICYT</fundingAgency><fundingNumber>PB96‐0606</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (<i>Petromyzon marinus</i> and <i>Lampetra fluviatilis</i>), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Acetylcholine in the Lamprey Brain</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain</title></titleInfo><name type="personal"><namePart type="given">Manuel A.</namePart><namePart type="family">Pombal</namePart><affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</affiliation><affiliation>Departamento de Biología Funcional y Ciencias de la Salud, Facultad de Ciencias, Universidad de Vigo, 36200 Vigo, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Oscar</namePart><namePart type="family">Marín</namePart><affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Agustín</namePart><namePart type="family">González</namePart><affiliation>Departamento de Biología Celular, Facultad de Biología, Universidad Complutense, 28040 Madrid, Spain</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>John Wiley & Sons, Inc.</publisher><place><placeTerm type="text">New York</placeTerm></place><dateIssued encoding="w3cdtf">2001-02-26</dateIssued><dateCaptured encoding="w3cdtf">2000-09-26</dateCaptured><dateValid encoding="w3cdtf">2000-11-29</dateValid><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">8</extent><extent unit="references">139</extent><extent unit="words">16787</extent></physicalDescription><abstract lang="en">The distribution of cholinergic neurons and fibers was studied immunohistochemically in the brain of two species of lampreys (Petromyzon marinus and Lampetra fluviatilis), by using an antiserum against choline acetyltransferase (ChAT). The results obtained in both species were similar, but there appeared some interspecies differences. In the forebrain, cholinergic cells were present in the striatum, preoptic region, paraventricular nucleus, pineal and parapineal organs, habenula, and pretectum. The cranial nerve motoneurons (III, IV, V, VI, VII, IX, and X), the first and second spino‐occipital nerves (so), and the ventral horn of the spinal cord showed a strong ChAT immunoreactivity. Additional cholinergic neurons were observed: the mesencephalic M5 nucleus of Schober, two different cell populations in the isthmic region, the efferent component of the eighth nerve, putative preganglionic parasympathetic cells, cells in the solitary tract nucleus, and the rhombencephalic reticular formation. Cholinergic fibers were widely distributed in the brain. Comparison with previous studies in other vertebrates suggests that major cholinergic pathways, like tectal innervation from the isthmic region, are also present in lampreys. Of particular interest was the prominent projection to the neurohypophysis from cholinergic neurons in the preoptic region and paraventricular nucleus. Present data were analyzed within the segmental paradigm, as was previously done in other vertebrates. Our results reveal that the organization of many cholinergic systems in the lamprey as, for example, in the striatal, preoptic, and isthmic regions, comprises features of the anamniote brain that remain common to all living amniotes studied so far, thus being conservative to a surprisingly high degree. Therefore, the distribution of ChAT‐immunoreactive structures in the lamprey brain is, in general, comparable to that previously described in other vertebrate species. J. Comp. Neurol. 431:105–126, 2001. © 2001 Wiley‐Liss, Inc.</abstract><note type="funding">Xunta de Galicia - No. PGIDT00PXI30112PR; </note><note type="funding">Spanish DGINV - No. PM99‐0072; </note><note type="funding">Spanish DGICYT - No. PB96‐0606; </note><subject lang="en"><genre>keywords</genre><topic>acetylcholine</topic><topic>motor nuclei</topic><topic>cyclostomes</topic><topic>segmentation</topic><topic>immunohistochemistry</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Comparative Neurology</title></titleInfo><titleInfo type="abbreviated"><title>J. Comp. Neurol.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic></subject><identifier type="ISSN">0021-9967</identifier><identifier type="eISSN">1096-9861</identifier><identifier type="DOI">10.1002/(ISSN)1096-9861</identifier><identifier type="PublisherID">CNE</identifier><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>431</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>105</start><end>126</end><total>22</total></extent></part></relatedItem><identifier type="istex">31F9207D96EB8F4B16DCEC6A130EF70606B4510C</identifier><identifier type="DOI">10.1002/1096-9861(20010226)431:1<105::AID-CNE1058>3.0.CO;2-P</identifier><identifier type="ArticleID">CNE1058</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2001 Wiley‐Liss, Inc.</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>John Wiley & Sons, Inc.</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001335 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 001335 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:31F9207D96EB8F4B16DCEC6A130EF70606B4510C
|texte= Distribution of choline acetyltransferase‐immunoreactive structures in the lamprey brain
}}
| This area was generated with Dilib version V0.6.27. |  |