The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton
Identifieur interne : 000E85 ( Istex/Corpus ); précédent : 000E84; suivant : 000E86The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton
Auteurs : Jasper Dewit ; P. Eckhard Witten ; Ann HuysseuneSource :
- Journal of Experimental Zoology Part B: Molecular and Developmental Evolution [ 1552-5007 ] ; 2011-12-15.
Abstract
A cartilaginous pectoral fin endoskeleton in zebrafish (Danio rerio) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011. © 2011 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/jez.b.21433
Links to Exploration step
ISTEX:0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title><author><name sortKey="Dewit, Jasper" sort="Dewit, Jasper" uniqKey="Dewit J" first="Jasper" last="Dewit">Jasper Dewit</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</mods:affiliation></affiliation></author><author><name sortKey="Witten, P Eckhard" sort="Witten, P Eckhard" uniqKey="Witten P" first="P. Eckhard" last="Witten">P. Eckhard Witten</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation><affiliation><mods:affiliation>Skretting Aquaculture Research Centre, Stavanger, Norway</mods:affiliation></affiliation></author><author><name sortKey="Huysseune, Ann" sort="Huysseune, Ann" uniqKey="Huysseune A" first="Ann" last="Huysseune">Ann Huysseune</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0</idno><date when="2011" year="2011">2011</date><idno type="doi">10.1002/jez.b.21433</idno><idno type="url">https://api.istex.fr/document/0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E85</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E85</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title><author><name sortKey="Dewit, Jasper" sort="Dewit, Jasper" uniqKey="Dewit J" first="Jasper" last="Dewit">Jasper Dewit</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</mods:affiliation></affiliation></author><author><name sortKey="Witten, P Eckhard" sort="Witten, P Eckhard" uniqKey="Witten P" first="P. Eckhard" last="Witten">P. Eckhard Witten</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation><affiliation><mods:affiliation>Skretting Aquaculture Research Centre, Stavanger, Norway</mods:affiliation></affiliation></author><author><name sortKey="Huysseune, Ann" sort="Huysseune, Ann" uniqKey="Huysseune A" first="Ann" last="Huysseune">Ann Huysseune</name><affiliation><mods:affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</title><title level="j" type="abbrev">J. Exp. Zool.</title><idno type="ISSN">1552-5007</idno><idno type="eISSN">1552-5015</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-12-15">2011-12-15</date><biblScope unit="volume">316B</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="584">584</biblScope><biblScope unit="page" to="597">597</biblScope></imprint><idno type="ISSN">1552-5007</idno></series><idno type="istex">0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0</idno><idno type="DOI">10.1002/jez.b.21433</idno><idno type="ArticleID">JEZ21433</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1552-5007</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A cartilaginous pectoral fin endoskeleton in zebrafish (Danio rerio) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011. © 2011 Wiley Periodicals, Inc.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Jasper Dewit</name><affiliations><json:string>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</json:string><json:string>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</json:string></affiliations></json:item><json:item><name>P. Eckhard Witten</name><affiliations><json:string>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</json:string><json:string>Skretting Aquaculture Research Centre, Stavanger, Norway</json:string></affiliations></json:item><json:item><name>Ann Huysseune</name><affiliations><json:string>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</json:string></affiliations></json:item></author><articleId><json:string>JEZ21433</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>A cartilaginous pectoral fin endoskeleton in zebrafish (Danio rerio) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011. © 2011 Wiley Periodicals, Inc.</abstract><qualityIndicators><score>7.292</score><pdfVersion>1.3</pdfVersion><pdfPageSize>593.972 x 792 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>1353</abstractCharCount><pdfWordCount>9352</pdfWordCount><pdfCharCount>57486</pdfCharCount><pdfPageCount>14</pdfPageCount><abstractWordCount>191</abstractWordCount></qualityIndicators><title>The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title><genre><json:string>article</json:string></genre><host><volume>316B</volume><publisherId><json:string>JEZ</json:string></publisherId><pages><total>14</total><last>597</last><first>584</first></pages><issn><json:string>1552-5007</json:string></issn><issue>8</issue><subject><json:item><value>Research Article</value></json:item></subject><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1552-5015</json:string></eissn><title>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</title><doi><json:string>10.1002/(ISSN)1552-5015</json:string></doi></host><publicationDate>2011</publicationDate><copyrightDate>2011</copyrightDate><doi><json:string>10.1002/jez.b.21433</json:string></doi><id>0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0</id><score>0.023475165</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><p>Copyright © 2011 Wiley Periodicals, Inc., A Wiley Company</p></availability><date>2011</date></publicationStmt><notesStmt><note>IWT (Belgium) - No. SB‐71465;</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title><author xml:id="author-1"><persName><forename type="first">Jasper</forename><surname>Dewit</surname></persName><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</affiliation></author><author xml:id="author-2"><persName><forename type="first">P. Eckhard</forename><surname>Witten</surname></persName><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation><affiliation>Skretting Aquaculture Research Centre, Stavanger, Norway</affiliation></author><author xml:id="author-3"><persName><forename type="first">Ann</forename><surname>Huysseune</surname></persName><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation></author></analytic><monogr><title level="j">Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</title><title level="j" type="abbrev">J. Exp. Zool.</title><idno type="pISSN">1552-5007</idno><idno type="eISSN">1552-5015</idno><idno type="DOI">10.1002/(ISSN)1552-5015</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2011-12-15"></date><biblScope unit="volume">316B</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="584">584</biblScope><biblScope unit="page" to="597">597</biblScope></imprint></monogr><idno type="istex">0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0</idno><idno type="DOI">10.1002/jez.b.21433</idno><idno type="ArticleID">JEZ21433</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2011</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>A cartilaginous pectoral fin endoskeleton in zebrafish (Danio rerio) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011. © 2011 Wiley Periodicals, Inc.</p></abstract><textClass><keywords scheme="Journal Subject"><list><head>article-category</head><item><term>Research Article</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2011-01-03">Received</change><change when="2011-06-24">Registration</change><change when="2011-12-15">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1552-5015</doi><issn type="print">1552-5007</issn><issn type="electronic">1552-5015</issn><idGroup><id type="product" value="JEZ"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF EXPERIMENTAL ZOOLOGY PART B: MOLECULAR AND DEVELOPMENTAL EVOLUTION">Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</title><title type="short">J. Exp. Zool.</title></titleGroup><selfCitationGroup><citation type="ancestor" xml:id="cit1"><journalTitle>Journal of Experimental Zoology</journalTitle><accessionId ref="info:x-wiley/issn/0022104X">0022-104X</accessionId><accessionId ref="info:x-wiley/issn/1097010X">1097-010X</accessionId><pubYear year="2004">2004</pubYear></citation></selfCitationGroup></publicationMeta><publicationMeta level="part" position="80"><doi origin="wiley" registered="yes">10.1002/jez.b.v316b.8</doi><numberingGroup><numbering type="journalVolume" number="316">316B</numbering><numbering type="journalIssue">8</numbering></numberingGroup><coverDate startDate="2011-12-15">15 December 2011</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="4" status="forIssue"><doi origin="wiley" registered="yes">10.1002/jez.b.21433</doi><idGroup><id type="unit" value="JEZ21433"></id></idGroup><countGroup><count type="pageTotal" number="14"></count></countGroup><titleGroup><title type="articleCategory">Research Article</title><title type="tocHeading1">Research Articles</title></titleGroup><copyright ownership="publisher">Copyright © 2011 Wiley Periodicals, Inc., A Wiley Company</copyright><eventGroup><event type="manuscriptReceived" date="2011-01-03"></event><event type="manuscriptRevised" date="2011-05-30"></event><event type="manuscriptAccepted" date="2011-06-24"></event><event type="xmlConverted" agent="Converter:JWSART34_TO_WML3G version:3.0 mode:FullText" date="2011-11-16"></event><event type="publishedOnlineEarlyUnpaginated" date="2011-08-10"></event><event type="firstOnline" date="2011-08-10"></event><event type="publishedOnlineFinalForm" date="2011-11-16"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:4.0.1" date="2014-03-19"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-30"></event></eventGroup><numberingGroup><numbering type="pageFirst">584</numbering><numbering type="pageLast">597</numbering></numberingGroup><correspondenceTo>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JEZ.JEZ21433.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="9"></count><count type="tableTotal" number="0"></count><count type="referenceTotal" number="75"></count></countGroup><titleGroup><title type="main" xml:lang="en">The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title><title type="short" xml:lang="en">MECHANISMS OF CARTILAGE SUBDIVISION</title></titleGroup><creators><creator xml:id="au1" creatorRole="author" affiliationRef="#af1" corresponding="yes"><personName><givenNames>Jasper</givenNames><familyName>Dewit</familyName></personName><contactDetails><email>jasper.dewit@ugent.be</email></contactDetails></creator><creator xml:id="au2" creatorRole="author" affiliationRef="#af1 #af2"><personName><givenNames>P. Eckhard</givenNames><familyName>Witten</familyName></personName></creator><creator xml:id="au3" creatorRole="author" affiliationRef="#af1"><personName><givenNames>Ann</givenNames><familyName>Huysseune</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="af1" countryCode="BE" type="organization"><unparsedAffiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</unparsedAffiliation></affiliation><affiliation xml:id="af2" countryCode="NO" type="organization"><unparsedAffiliation>Skretting Aquaculture Research Centre, Stavanger, Norway</unparsedAffiliation></affiliation></affiliationGroup><fundingInfo><fundingAgency>IWT (Belgium)</fundingAgency><fundingNumber>SB‐71465</fundingNumber></fundingInfo><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>A cartilaginous pectoral fin endoskeleton in zebrafish (<i>Danio rerio</i>) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. <i>J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011</i>. © 2011 Wiley Periodicals, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>MECHANISMS OF CARTILAGE SUBDIVISION</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton</title></titleInfo><name type="personal"><namePart type="given">Jasper</namePart><namePart type="family">Dewit</namePart><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, 9000 Ghent, Belgium===</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P. Eckhard</namePart><namePart type="family">Witten</namePart><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation><affiliation>Skretting Aquaculture Research Centre, Stavanger, Norway</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ann</namePart><namePart type="family">Huysseune</namePart><affiliation>Research Group Evolutionary Developmental Biology, Biology Department, Ghent University, Ghent, Belgium</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2011-12-15</dateIssued><dateCaptured encoding="w3cdtf">2011-01-03</dateCaptured><dateValid encoding="w3cdtf">2011-06-24</dateValid><copyrightDate encoding="w3cdtf">2011</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">9</extent><extent unit="references">75</extent></physicalDescription><abstract lang="en">A cartilaginous pectoral fin endoskeleton in zebrafish (Danio rerio) develops early, after which the cartilage of the larval fin endoskeleton undergoes a complete transformation into the adult morphology. This transformation includes multiple subdivisions of a single cartilaginous disk. The type of cartilage subdivision is unique to teleost fish. In this study, we present the timing and the developmental features of these subdivisions and we discuss variation in this process, caused by differences in growth rate. We establish that the cartilage subdivisions are developmentally linked to the formation of lepidotrichia in the fin fold. At the cellular level, we show that neither apoptosis nor resorption by chondroclasts and/or macrophages contributes to the cartilage subdivision. Ultrastructural observations show dedifferentiation of chondrocytes in subdivision zones. Different from forelimb development in other vertebrates, dedifferentiation is an important mechanism in the development of the adult pectoral fin skeleton. We here provide further support for the idea that the phenotype of skeletal tissues is not terminal and that plasticity of differentiated connective tissues can play an important role in various developmental and homeostatic processes. J. Exp. Zool. (Mol. Dev. Evol.) 316:584–597, 2011. © 2011 Wiley Periodicals, Inc.</abstract><note type="funding">IWT (Belgium) - No. SB‐71465; </note><relatedItem type="host"><titleInfo><title>Journal of Experimental Zoology Part B: Molecular and Developmental Evolution</title></titleInfo><titleInfo type="abbreviated"><title>J. Exp. Zool.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Research Article</topic></subject><identifier type="ISSN">1552-5007</identifier><identifier type="eISSN">1552-5015</identifier><identifier type="DOI">10.1002/(ISSN)1552-5015</identifier><identifier type="PublisherID">JEZ</identifier><part><date>2011</date><detail type="volume"><caption>vol.</caption><number>316B</number></detail><detail type="issue"><caption>no.</caption><number>8</number></detail><extent unit="pages"><start>584</start><end>597</end><total>14</total></extent></part></relatedItem><relatedItem type="preceding"><titleInfo><title>Journal of Experimental Zoology</title></titleInfo><identifier type="ISSN">0022-104X</identifier><identifier type="ISSN">1097-010X</identifier><part><date point="end">2004</date></part></relatedItem><identifier type="istex">0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0</identifier><identifier type="DOI">10.1002/jez.b.21433</identifier><identifier type="ArticleID">JEZ21433</identifier><accessCondition type="use and reproduction" contentType="copyright">Copyright © 2011 Wiley Periodicals, Inc., A Wiley Company</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Wiley Subscription Services, Inc., A Wiley Company</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000E85 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000E85 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:0A657ACAD3FB12DF713F0158C1AE7EF5D46B5DB0
|texte= The mechanism of cartilage subdivision in the reorganization of the zebrafish pectoral fin endoskeleton
}}
| This area was generated with Dilib version V0.6.27. |  |