Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, Cirrhinus mrigala (Hamilton)
Identifieur interne : 000E27 ( Istex/Corpus ); précédent : 000E26; suivant : 000E28Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, Cirrhinus mrigala (Hamilton)
Auteurs : Pratap Chandra Das ; S. Ayyappan ; J K Jena ; B K DasSource :
- Aquaculture Research [ 1355-557X ] ; 2004-01.
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Abstract
A comprehensive acute toxicity trial was conducted using a static water system to study the toxic effect of ammonia on haematology and enzyme profiles of Cirrhinus mrigala H. The LC50 of total ammonia‐nitrogen (TAN) was 11.8 mg L−1 TAN (1.029 mg L−1 NH3‐N). The sub‐lethal test revealed that with increasing concentration of TAN, the total erythrocyte counts were reduced in lower concentrations (1–4 mg L−1 TAN) followed by higher levels in fish exposed to higher concentrations (8–16 mg L−1 TAN). In contrast, the total leucocyte counts were opposite. With increasing concentration of TAN, haemoglobin and serum protein content were reduced, whereas the blood glucose level increased. As the concentration of ammonia increased, there was a reduction in acetylecholinesterase activity in the brain and liver; alkaline phosphatase activity in the serum, brain and gill; and acid phosphatase (ACP) activity in the gill. The activity of lactate dehydrogenase in the gill, liver, kidney and brain increased with increased concentration of ammonia. In addition, activities of ACP in the serum and brain, alanine aminotransferase in the serum, brain and gill, and aspartate aminotransferase in the serum, brain and gill were increased.
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DOI: 10.1111/j.1365-2109.2004.00994.x
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Ayyappan</name></author><author><name sortKey="Jena, J K" sort="Jena, J K" uniqKey="Jena J" first="J K" last="Jena">J K Jena</name><affiliation><mods:affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</mods:affiliation></affiliation></author><author><name sortKey="Das, B K" sort="Das, B K" uniqKey="Das B" first="B K" last="Das">B K Das</name><affiliation><mods:affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:464F6B2082DD3059147162950020B4312BCA4B80</idno><date when="2004" year="2004">2004</date><idno type="doi">10.1111/j.1365-2109.2004.00994.x</idno><idno type="url">https://api.istex.fr/document/464F6B2082DD3059147162950020B4312BCA4B80/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E27</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, Cirrhinus mrigala (Hamilton)</title><author><name sortKey="Das, Pratap Chandra" sort="Das, Pratap Chandra" uniqKey="Das P" first="Pratap Chandra" last="Das">Pratap Chandra Das</name><affiliation><mods:affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</mods:affiliation></affiliation></author><author><name sortKey="Ayyappan, S" sort="Ayyappan, S" uniqKey="Ayyappan S" first="S" last="Ayyappan">S. Ayyappan</name></author><author><name sortKey="Jena, J K" sort="Jena, J K" uniqKey="Jena J" first="J K" last="Jena">J K Jena</name><affiliation><mods:affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</mods:affiliation></affiliation></author><author><name sortKey="Das, B K" sort="Das, B K" uniqKey="Das B" first="B K" last="Das">B K Das</name><affiliation><mods:affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Aquaculture Research</title><idno type="ISSN">1355-557X</idno><idno type="eISSN">1365-2109</idno><imprint><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2004-01">2004-01</date><biblScope unit="volume">35</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="134">134</biblScope><biblScope unit="page" to="143">143</biblScope></imprint><idno type="ISSN">1355-557X</idno></series><idno type="istex">464F6B2082DD3059147162950020B4312BCA4B80</idno><idno type="DOI">10.1111/j.1365-2109.2004.00994.x</idno><idno type="ArticleID">ARE994</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1355-557X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cirrhinus mrigala H.</term><term>ammonia</term><term>enzyme</term><term>haematology</term><term>toxicity</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A comprehensive acute toxicity trial was conducted using a static water system to study the toxic effect of ammonia on haematology and enzyme profiles of Cirrhinus mrigala H. The LC50 of total ammonia‐nitrogen (TAN) was 11.8 mg L−1 TAN (1.029 mg L−1 NH3‐N). The sub‐lethal test revealed that with increasing concentration of TAN, the total erythrocyte counts were reduced in lower concentrations (1–4 mg L−1 TAN) followed by higher levels in fish exposed to higher concentrations (8–16 mg L−1 TAN). In contrast, the total leucocyte counts were opposite. With increasing concentration of TAN, haemoglobin and serum protein content were reduced, whereas the blood glucose level increased. As the concentration of ammonia increased, there was a reduction in acetylecholinesterase activity in the brain and liver; alkaline phosphatase activity in the serum, brain and gill; and acid phosphatase (ACP) activity in the gill. The activity of lactate dehydrogenase in the gill, liver, kidney and brain increased with increased concentration of ammonia. In addition, activities of ACP in the serum and brain, alanine aminotransferase in the serum, brain and gill, and aspartate aminotransferase in the serum, brain and gill were increased.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>Pratap Chandra Das</name><affiliations><json:string>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</json:string></affiliations></json:item><json:item><name>S Ayyappan</name></json:item><json:item><name>J K Jena</name><affiliations><json:string>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</json:string></affiliations></json:item><json:item><name>B K Das</name><affiliations><json:string>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Cirrhinus mrigala H.</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>ammonia</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>toxicity</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>haematology</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>enzyme</value></json:item></subject><articleId><json:string>ARE994</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>A comprehensive acute toxicity trial was conducted using a static water system to study the toxic effect of ammonia on haematology and enzyme profiles of Cirrhinus mrigala H. 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E‐mail: <email normalForm="pratapcdas@yahoo.com">pratapcdas@yahoo.com</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:ARE.ARE994.pdf"></link></linkGroup></publicationMeta><contentMeta><countGroup><count type="figureTotal" number="7"></count><count type="tableTotal" number="1"></count><count type="formulaTotal" number="2"></count><count type="referenceTotal" number="51"></count><count type="wordTotal" number="7186"></count><count type="linksCrossRef" number="78"></count></countGroup><titleGroup><title type="main">Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, <i>Cirrhinus mrigala</i> (Hamilton)</title><title type="shortAuthors">P C Das <i>et al.</i></title><title type="short">Ammonia toxicity to fingerlings of <i>C. mrigala</i> H.</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#aff-1-1"><personName><givenNames>Pratap Chandra</givenNames><familyName>Das</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" noteRef="#fn1"><personName><givenNames>S</givenNames><familyName>Ayyappan</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#aff-1-1"><personName><givenNames>J K</givenNames><familyName>Jena</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#aff-1-1"><personName><givenNames>B K</givenNames><familyName>Das</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="aff-1-1" countryCode="IN"><unparsedAffiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1"><i>Cirrhinus mrigala</i> H.</keyword><keyword xml:id="k2">ammonia</keyword><keyword xml:id="k3">toxicity</keyword><keyword xml:id="k4">haematology</keyword><keyword xml:id="k5">enzyme</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><title type="main">Abstract</title><p>A comprehensive acute toxicity trial was conducted using a static water system to study the toxic effect of ammonia on haematology and enzyme profiles of <i>Cirrhinus mrigala</i> H. The LC<sub>50</sub> of total ammonia‐nitrogen (TAN) was 11.8 mg L<sup>−1</sup> TAN (1.029 mg L<sup>−1</sup> NH<sub>3</sub>‐N). The sub‐lethal test revealed that with increasing concentration of TAN, the total erythrocyte counts were reduced in lower concentrations (1–4 mg L<sup>−1</sup> TAN) followed by higher levels in fish exposed to higher concentrations (8–16 mg L<sup>−1</sup> TAN). In contrast, the total leucocyte counts were opposite. With increasing concentration of TAN, haemoglobin and serum protein content were reduced, whereas the blood glucose level increased. As the concentration of ammonia increased, there was a reduction in acetylecholinesterase activity in the brain and liver; alkaline phosphatase activity in the serum, brain and gill; and acid phosphatase (ACP) activity in the gill. The activity of lactate dehydrogenase in the gill, liver, kidney and brain increased with increased concentration of ammonia. In addition, activities of ACP in the serum and brain, alanine aminotransferase in the serum, brain and gill, and aspartate aminotransferase in the serum, brain and gill were increased.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1" numbered="no"><p><sup>*</sup><b>Present address:</b> Krishi Anusandhan Bhavan‐2, Indian Council of Agricultural Research, Pusa, New Delhi 110 012, India.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, Cirrhinus mrigala (Hamilton)</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Ammonia toxicity to fingerlings of C. mrigala H.</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Acute toxicity of ammonia and its sub‐lethal effects on selected haematological and enzymatic parameters of mrigal, Cirrhinus mrigala (Hamilton)</title></titleInfo><name type="personal"><namePart type="given">Pratap Chandra</namePart><namePart type="family">Das</namePart><affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Ayyappan</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J K</namePart><namePart type="family">Jena</namePart><affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B K</namePart><namePart type="family">Das</namePart><affiliation>Central Institute of Freshwater Aquaculture, Bhubaneswar, Orissa, India</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Blackwell Science Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2004-01</dateIssued><copyrightDate encoding="w3cdtf">2004</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">7</extent><extent unit="tables">1</extent><extent unit="formulas">2</extent><extent unit="references">51</extent><extent unit="words">7186</extent></physicalDescription><abstract lang="en">A comprehensive acute toxicity trial was conducted using a static water system to study the toxic effect of ammonia on haematology and enzyme profiles of Cirrhinus mrigala H. The LC50 of total ammonia‐nitrogen (TAN) was 11.8 mg L−1 TAN (1.029 mg L−1 NH3‐N). The sub‐lethal test revealed that with increasing concentration of TAN, the total erythrocyte counts were reduced in lower concentrations (1–4 mg L−1 TAN) followed by higher levels in fish exposed to higher concentrations (8–16 mg L−1 TAN). In contrast, the total leucocyte counts were opposite. With increasing concentration of TAN, haemoglobin and serum protein content were reduced, whereas the blood glucose level increased. As the concentration of ammonia increased, there was a reduction in acetylecholinesterase activity in the brain and liver; alkaline phosphatase activity in the serum, brain and gill; and acid phosphatase (ACP) activity in the gill. The activity of lactate dehydrogenase in the gill, liver, kidney and brain increased with increased concentration of ammonia. In addition, activities of ACP in the serum and brain, alanine aminotransferase in the serum, brain and gill, and aspartate aminotransferase in the serum, brain and gill were increased.</abstract><subject lang="en"><genre>keywords</genre><topic>Cirrhinus mrigala H.</topic><topic>ammonia</topic><topic>toxicity</topic><topic>haematology</topic><topic>enzyme</topic></subject><relatedItem type="host"><titleInfo><title>Aquaculture Research</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">1355-557X</identifier><identifier type="eISSN">1365-2109</identifier><identifier type="DOI">10.1111/(ISSN)1365-2109</identifier><identifier type="PublisherID">ARE</identifier><part><date>2004</date><detail type="volume"><caption>vol.</caption><number>35</number></detail><detail type="issue"><caption>no.</caption><number>2</number></detail><extent unit="pages"><start>134</start><end>143</end><total>10</total></extent></part></relatedItem><identifier type="istex">464F6B2082DD3059147162950020B4312BCA4B80</identifier><identifier type="DOI">10.1111/j.1365-2109.2004.00994.x</identifier><identifier type="ArticleID">ARE994</identifier><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Science Ltd</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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