The Bigger the C-Value, the Larger the Cell: Genome Size and Red Blood Cell Size in Vertebrates
Identifieur interne : 000B88 ( Istex/Checkpoint ); précédent : 000B87; suivant : 000B89The Bigger the C-Value, the Larger the Cell: Genome Size and Red Blood Cell Size in Vertebrates
Auteurs : T. Ryan GregorySource :
- Blood Cells, Molecules and Diseases [ 1079-9796 ] ; 2001.
Abstract
ABSTRACT Vertebrate genome sizes vary roughly 350-fold and correlate with a variety of cellular and organismal parameters. Most notable among these is the relationship between genome size (“C-value”) and red blood cell (RBC) size, which can be identified within and among each of the five vertebrate classes. This relationship, in turn, leads to important associations between genome size and features such as metabolic rate (at least in homeotherms). The present article describes the correlation between genome size and RBC size in vertebrates and discusses some of the cytological, physiological, and evolutionary implications of this relationship.
Url:
DOI: 10.1006/bcmd.2001.0457
Affiliations:
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<front><div type="abstract" xml:lang="en">ABSTRACT Vertebrate genome sizes vary roughly 350-fold and correlate with a variety of cellular and organismal parameters. Most notable among these is the relationship between genome size (“C-value”) and red blood cell (RBC) size, which can be identified within and among each of the five vertebrate classes. This relationship, in turn, leads to important associations between genome size and features such as metabolic rate (at least in homeotherms). The present article describes the correlation between genome size and RBC size in vertebrates and discusses some of the cytological, physiological, and evolutionary implications of this relationship.</div>
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