Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.
Identifieur interne : 001149 ( Main/Exploration ); précédent : 001148; suivant : 001150Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.
Auteurs : Barry K. Logan [Oman] ; Amanda L A. Mohr [États-Unis] ; Stephen K. Talpins [États-Unis]Source :
- Journal of analytical toxicology [ 1945-2403 ] ; 2014.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Conception d'appareillage (MeSH), Conduite automobile (législation et jurisprudence), Crime (MeSH), Détection d'abus de substances (instrumentation), Détection d'abus de substances (méthodes), Femelle (MeSH), Floride (MeSH), Humains (MeSH), Jeune adulte (MeSH), Manipulation d'échantillons (MeSH), Mâle (MeSH), Reproductibilité des résultats (MeSH), Salive (composition chimique), Sensibilité et spécificité (MeSH), Sujet âgé (MeSH), Troubles liés à une substance (diagnostic), Troubles liés à une substance (épidémiologie), Études de cohortes (MeSH).
- MESH :
- composition chimique : Salive.
- diagnostic : Troubles liés à une substance.
- législation et jurisprudence : Conduite automobile.
- méthodes : Détection d'abus de substances.
- épidémiologie : Détection d'abus de substances, Troubles liés à une substance.
- Adolescent, Adulte, Adulte d'âge moyen, Conception d'appareillage, Crime, Femelle, Floride, Humains, Jeune adulte, Manipulation d'échantillons, Mâle, Reproductibilité des résultats, Sensibilité et spécificité, Sujet âgé, Études de cohortes.
English descriptors
- KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Automobile Driving (legislation & jurisprudence), Cohort Studies (MeSH), Crime (MeSH), Equipment Design (MeSH), Female (MeSH), Florida (MeSH), Humans (MeSH), Illicit Drugs (analysis), Illicit Drugs (urine), Male (MeSH), Middle Aged (MeSH), Reproducibility of Results (MeSH), Saliva (chemistry), Sensitivity and Specificity (MeSH), Specimen Handling (MeSH), Substance Abuse Detection (instrumentation), Substance Abuse Detection (methods), Substance-Related Disorders (diagnosis), Substance-Related Disorders (epidemiology), Young Adult (MeSH).
- MESH :
- chemical , analysis : Illicit Drugs.
- chemical , urine : Illicit Drugs.
- geographic : Florida.
- chemistry : Saliva.
- diagnosis : Substance-Related Disorders.
- epidemiology : Substance-Related Disorders.
- instrumentation : Substance Abuse Detection.
- legislation & jurisprudence : Automobile Driving.
- methods : Substance Abuse Detection.
- Adolescent, Adult, Aged, Cohort Studies, Crime, Equipment Design, Female, Humans, Male, Middle Aged, Reproducibility of Results, Sensitivity and Specificity, Specimen Handling, Young Adult.
Abstract
The use of oral fluid (OF) drug testing devices offers the ability to rapidly obtain a drug screening result at the time of a traffic stop. We describe an evaluation of two such devices, the Dräger Drug Test 5000 and the Affiniton DrugWipe, to detect drug use in a cohort of drivers arrested from an investigation of drug impaired driving (n = 92). Overall, 41% of these drivers were ultimately confirmed positive by mass spectrometry for the presence of one or more drugs. The most frequently detected drugs were cannabinoids (30%), benzodiazepines (11%) and cocaine (10%). Thirty-nine percent of drivers with blood alcohol concentrations >0.08 g/100 mL were found to be drug positive. Field test results obtained from OF samples were compared with collected OF and urine samples subsequently analyzed in the laboratory by gas or liquid chromatography-mass spectrometry. The Dräger Drug Test 5000 (DDT5000) and DrugWipe returned overall sensitivities of 51 and 53%, and positive predictive values of 93 and 63%, respectively. The most notable difference in performance was the DDT5000's better sensitivity in detecting marijuana use. Both devices failed to detect benzodiazepine use. Oral fluid proved to be a more effective confirmatory specimen, with more drugs being confirmed in OF than urine.
DOI: 10.1093/jat/bku050
PubMed: 24894458
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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(MeSH)</term><term>Manipulation d'échantillons (MeSH)</term><term>Mâle (MeSH)</term><term>Reproductibilité des résultats (MeSH)</term><term>Salive (composition chimique)</term><term>Sensibilité et spécificité (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Troubles liés à une substance (diagnostic)</term><term>Troubles liés à une substance (épidémiologie)</term><term>Études de cohortes (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Illicit Drugs</term></keywords><keywords scheme="MESH" type="chemical" qualifier="urine" xml:lang="en"><term>Illicit Drugs</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Florida</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Salive</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Substance-Related 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devices offers the ability to rapidly obtain a drug screening result at the time of a traffic stop. We describe an evaluation of two such devices, the Dräger Drug Test 5000 and the Affiniton DrugWipe, to detect drug use in a cohort of drivers arrested from an investigation of drug impaired driving (n = 92). Overall, 41% of these drivers were ultimately confirmed positive by mass spectrometry for the presence of one or more drugs. The most frequently detected drugs were cannabinoids (30%), benzodiazepines (11%) and cocaine (10%). Thirty-nine percent of drivers with blood alcohol concentrations >0.08 g/100 mL were found to be drug positive. Field test results obtained from OF samples were compared with collected OF and urine samples subsequently analyzed in the laboratory by gas or liquid chromatography-mass spectrometry. The Dräger Drug Test 5000 (DDT5000) and DrugWipe returned overall sensitivities of 51 and 53%, and positive predictive values of 93 and 63%, respectively. The most notable difference in performance was the DDT5000's better sensitivity in detecting marijuana use. Both devices failed to detect benzodiazepine use. Oral fluid proved to be a more effective confirmatory specimen, with more drugs being confirmed in OF than urine. </div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24894458</PMID><DateCompleted><Year>2015</Year><Month>04</Month><Day>08</Day></DateCompleted><DateRevised><Year>2019</Year><Month>12</Month><Day>10</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1945-2403</ISSN><JournalIssue CitedMedium="Internet"><Volume>38</Volume><Issue>7</Issue><PubDate><Year>2014</Year><Month>Sep</Month></PubDate></JournalIssue><Title>Journal of analytical toxicology</Title><ISOAbbreviation>J Anal Toxicol</ISOAbbreviation></Journal><ArticleTitle>Detection and prevalence of drug use in arrested drivers using the Dräger Drug Test 5000 and Affiniton DrugWipe oral fluid drug screening devices.</ArticleTitle><Pagination><MedlinePgn>444-50</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/jat/bku050</ELocationID><Abstract><AbstractText>The use of oral fluid (OF) drug testing devices offers the ability to rapidly obtain a drug screening result at the time of a traffic stop. We describe an evaluation of two such devices, the Dräger Drug Test 5000 and the Affiniton DrugWipe, to detect drug use in a cohort of drivers arrested from an investigation of drug impaired driving (n = 92). Overall, 41% of these drivers were ultimately confirmed positive by mass spectrometry for the presence of one or more drugs. The most frequently detected drugs were cannabinoids (30%), benzodiazepines (11%) and cocaine (10%). Thirty-nine percent of drivers with blood alcohol concentrations >0.08 g/100 mL were found to be drug positive. Field test results obtained from OF samples were compared with collected OF and urine samples subsequently analyzed in the laboratory by gas or liquid chromatography-mass spectrometry. The Dräger Drug Test 5000 (DDT5000) and DrugWipe returned overall sensitivities of 51 and 53%, and positive predictive values of 93 and 63%, respectively. The most notable difference in performance was the DDT5000's better sensitivity in detecting marijuana use. Both devices failed to detect benzodiazepine use. Oral fluid proved to be a more effective confirmatory specimen, with more drugs being confirmed in OF than urine. </AbstractText><CopyrightInformation>© The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Logan</LastName><ForeName>Barry K</ForeName><Initials>BK</Initials><AffiliationInfo><Affiliation>The Center for Forensic Science Research and Education, Willow Grove, PA, USA NMS Labs, Willow Grove, PA, USA Barry.Logan@nmslabs.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mohr</LastName><ForeName>Amanda L A</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>The Center for Forensic Science Research and Education, Willow Grove, PA, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Talpins</LastName><ForeName>Stephen K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Institute for Behavior and Health Inc., Rockville, MD, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>06</Month><Day>03</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Anal Toxicol</MedlineTA><NlmUniqueID>7705085</NlmUniqueID><ISSNLinking>0146-4760</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013287">Illicit Drugs</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Anal Toxicol. 2015 May;39(4):332-3</RefSource><PMID Version="1">25698776</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>J Anal Toxicol. 2015 May;39(4):330-1</RefSource><PMID Version="1">25698778</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001334" MajorTopicYN="N">Automobile Driving</DescriptorName><QualifierName UI="Q000331" MajorTopicYN="Y">legislation & jurisprudence</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003415" MajorTopicYN="Y">Crime</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004867" MajorTopicYN="N">Equipment Design</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005431" MajorTopicYN="N" Type="Geographic">Florida</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013287" MajorTopicYN="N">Illicit Drugs</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013048" MajorTopicYN="N">Specimen Handling</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015813" MajorTopicYN="Y">Substance Abuse Detection</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019966" MajorTopicYN="Y">Substance-Related Disorders</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>6</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>4</Month><Day>9</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">24894458</ArticleId><ArticleId IdType="pii">bku050</ArticleId><ArticleId IdType="doi">10.1093/jat/bku050</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Oman</li><li>États-Unis</li></country><region><li>Maryland</li><li>Pennsylvanie</li></region></list><tree><country name="Oman"><noRegion><name sortKey="Logan, Barry K" sort="Logan, Barry K" uniqKey="Logan B" first="Barry K" last="Logan">Barry K. Logan</name></noRegion></country><country name="États-Unis"><region name="Pennsylvanie"><name sortKey="Mohr, Amanda L A" sort="Mohr, Amanda L A" uniqKey="Mohr A" first="Amanda L A" last="Mohr">Amanda L A. Mohr</name></region><name sortKey="Talpins, Stephen K" sort="Talpins, Stephen K" uniqKey="Talpins S" first="Stephen K" last="Talpins">Stephen K. Talpins</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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