Predictors of Quality of Life Following Cognitive Processing Therapy Among Women and Men With Post-Traumatic Stress Disorder.
Identifieur interne : 000118 ( Main/Exploration ); précédent : 000117; suivant : 000119Predictors of Quality of Life Following Cognitive Processing Therapy Among Women and Men With Post-Traumatic Stress Disorder.
Auteurs : Lisa H. Glassman [États-Unis] ; Margaret-Anne Mackintosh [États-Unis] ; Stephanie Y. Wells [États-Unis] ; Induni Wickramasinghe [États-Unis] ; Kristen H. Walter [États-Unis] ; Leslie A. Morland [États-Unis]Source :
- Military medicine [ 1930-613X ] ; 2020.
Abstract
INTRODUCTION
The effect of evidence-based post-traumatic stress disorder (PTSD) treatments on quality of life (QOL) is not well understood. In light of mixed findings on QOL after PTSD interventions, little is known about why some individuals experience functional and QOL improvements while others do not. This study examined treatment-related changes in depression, anger, and PTSD following cognitive processing therapy (CPT) as potential predictors of QOL change.
MATERIALS AND METHODS
Data from two randomized controlled trials, one examining CPT among female civilians and veterans (women's study NCT02362477; n = 126) and the other on CPT delivered to male veterans (men's study NCT00879255; n = 125), were used to test study aims. Linear mixed modeling examined changes in depression, anger, and PTSD as predictors of post-treatment QOL while controlling for baseline QOL. The VA Pacific Island Health Care System's Institutional Review Board approved all study procedures.
RESULTS
Among women, reductions in depression from pre- to post-treatment had the strongest predictive value of post-treatment QOL (B = -1.15, 95% confidence interval (-1.71, -0.60), t = -4.07, P < .001). For men, reductions in trait anger from pre- to post-treatment predicted post-treatment QOL (B = -0.55, 95% confidence interval (-0.90, -0.19), t = -3.00, P = .003).
CONCLUSIONS
Improvements in QOL may be predicted by different symptoms for men and women following evidence-based PTSD treatment. Our findings suggest that change in depression symptoms is an important predictor of post-treatment QOL among women, while anger symptoms are more influential for men. QOL and functioning is underresearched within the context of PTSD treatment, and this study suggests that these domains should be examined within the context of gender.
DOI: 10.1093/milmed/usz474
PubMed: 32077948
Affiliations:
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Glassman</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego</wicri:cityArea></affiliation></author><author><name sortKey="Mackintosh, Margaret Anne" sort="Mackintosh, Margaret Anne" uniqKey="Mackintosh M" first="Margaret-Anne" last="Mackintosh">Margaret-Anne Mackintosh</name><affiliation wicri:level="2"><nlm:affiliation>Dissemination and Training Division, National Center for PTSD: 795 Willow Rd (NC-PTSD), Building 334, Menlo Park, CA 94025.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Dissemination and Training Division, National Center for PTSD: 795 Willow Rd (NC-PTSD), Building 334, Menlo Park</wicri:cityArea></affiliation></author><author><name sortKey="Wells, Stephanie Y" sort="Wells, Stephanie Y" uniqKey="Wells S" first="Stephanie Y" last="Wells">Stephanie Y. Wells</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego, CA 92182.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego</wicri:cityArea></affiliation></author><author><name sortKey="Wickramasinghe, Induni" sort="Wickramasinghe, Induni" uniqKey="Wickramasinghe I" first="Induni" last="Wickramasinghe">Induni Wickramasinghe</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego</wicri:cityArea></affiliation></author><author><name sortKey="Walter, Kristen H" sort="Walter, Kristen H" uniqKey="Walter K" first="Kristen H" last="Walter">Kristen H. Walter</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego</wicri:cityArea></affiliation></author><author><name sortKey="Morland, Leslie A" sort="Morland, Leslie A" uniqKey="Morland L" first="Leslie A" last="Morland">Leslie A. Morland</name><affiliation wicri:level="2"><nlm:affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego, CA 92182.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Californie</region></placeName><wicri:cityArea>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:affiliation>Department of Veterans Affairs Pacific Islands Healthcare System, National Center for PTSD - Pacific Islands Division: 3375 Koapaka Street, Suite I-560 Honolulu, Hawaii 96819.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Hawaï</region></placeName><wicri:cityArea>Department of Veterans Affairs Pacific Islands Healthcare System, National Center for PTSD - Pacific Islands Division: 3375 Koapaka Street, Suite I-560 Honolulu</wicri:cityArea></affiliation></author></analytic><series><title level="j">Military medicine</title><idno type="eISSN">1930-613X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>INTRODUCTION</b></p><p>The effect of evidence-based post-traumatic stress disorder (PTSD) treatments on quality of life (QOL) is not well understood. In light of mixed findings on QOL after PTSD interventions, little is known about why some individuals experience functional and QOL improvements while others do not. This study examined treatment-related changes in depression, anger, and PTSD following cognitive processing therapy (CPT) as potential predictors of QOL change.</p></div><div type="abstract" xml:lang="en"><p><b>MATERIALS AND METHODS</b></p><p>Data from two randomized controlled trials, one examining CPT among female civilians and veterans (women's study NCT02362477; n = 126) and the other on CPT delivered to male veterans (men's study NCT00879255; n = 125), were used to test study aims. Linear mixed modeling examined changes in depression, anger, and PTSD as predictors of post-treatment QOL while controlling for baseline QOL. The VA Pacific Island Health Care System's Institutional Review Board approved all study procedures.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Among women, reductions in depression from pre- to post-treatment had the strongest predictive value of post-treatment QOL (B = -1.15, 95% confidence interval (-1.71, -0.60), t = -4.07, P < .001). For men, reductions in trait anger from pre- to post-treatment predicted post-treatment QOL (B = -0.55, 95% confidence interval (-0.90, -0.19), t = -3.00, P = .003).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>Improvements in QOL may be predicted by different symptoms for men and women following evidence-based PTSD treatment. Our findings suggest that change in depression symptoms is an important predictor of post-treatment QOL among women, while anger symptoms are more influential for men. QOL and functioning is underresearched within the context of PTSD treatment, and this study suggests that these domains should be examined within the context of gender.</p></div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">32077948</PMID><DateRevised><Year>2020</Year><Month>08</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1930-613X</ISSN><JournalIssue CitedMedium="Internet"><Volume>185</Volume><Issue>5-6</Issue><PubDate><Year>2020</Year><Month>06</Month><Day>08</Day></PubDate></JournalIssue><Title>Military medicine</Title><ISOAbbreviation>Mil Med</ISOAbbreviation></Journal><ArticleTitle>Predictors of Quality of Life Following Cognitive Processing Therapy Among Women and Men With Post-Traumatic Stress Disorder.</ArticleTitle><Pagination><MedlinePgn>e579-e585</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/milmed/usz474</ELocationID><Abstract><AbstractText Label="INTRODUCTION">The effect of evidence-based post-traumatic stress disorder (PTSD) treatments on quality of life (QOL) is not well understood. In light of mixed findings on QOL after PTSD interventions, little is known about why some individuals experience functional and QOL improvements while others do not. This study examined treatment-related changes in depression, anger, and PTSD following cognitive processing therapy (CPT) as potential predictors of QOL change.</AbstractText><AbstractText Label="MATERIALS AND METHODS">Data from two randomized controlled trials, one examining CPT among female civilians and veterans (women's study NCT02362477; n = 126) and the other on CPT delivered to male veterans (men's study NCT00879255; n = 125), were used to test study aims. Linear mixed modeling examined changes in depression, anger, and PTSD as predictors of post-treatment QOL while controlling for baseline QOL. The VA Pacific Island Health Care System's Institutional Review Board approved all study procedures.</AbstractText><AbstractText Label="RESULTS">Among women, reductions in depression from pre- to post-treatment had the strongest predictive value of post-treatment QOL (B = -1.15, 95% confidence interval (-1.71, -0.60), t = -4.07, P < .001). For men, reductions in trait anger from pre- to post-treatment predicted post-treatment QOL (B = -0.55, 95% confidence interval (-0.90, -0.19), t = -3.00, P = .003).</AbstractText><AbstractText Label="CONCLUSIONS">Improvements in QOL may be predicted by different symptoms for men and women following evidence-based PTSD treatment. Our findings suggest that change in depression symptoms is an important predictor of post-treatment QOL among women, while anger symptoms are more influential for men. QOL and functioning is underresearched within the context of PTSD treatment, and this study suggests that these domains should be examined within the context of gender.</AbstractText><CopyrightInformation>Published by Oxford University Press on behalf of the Association of Military Surgeons of the United States 2020. This work is written by US Government employees and is in the public domain in the US.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Glassman</LastName><ForeName>Lisa H</ForeName><Initials>LH</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mackintosh</LastName><ForeName>Margaret-Anne</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Dissemination and Training Division, National Center for PTSD: 795 Willow Rd (NC-PTSD), Building 334, Menlo Park, CA 94025.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wells</LastName><ForeName>Stephanie Y</ForeName><Initials>SY</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego, CA 92182.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wickramasinghe</LastName><ForeName>Induni</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Walter</LastName><ForeName>Kristen H</ForeName><Initials>KH</Initials><AffiliationInfo><Affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Morland</LastName><ForeName>Leslie A</ForeName><Initials>LA</Initials><AffiliationInfo><Affiliation>Department of Psychiatry, University of California, San Diego: 9500 Gilman Dr, La Jolla, CA 92093.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, VA San Diego Healthcare System: 3350 La Jolla Village Drive (664BU), San Diego, CA 92161.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Psychology, San Diego State University: 5500 Campanile Dr, San Diego, CA 92182.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Veterans Affairs Pacific Islands Healthcare System, National Center for PTSD - Pacific Islands Division: 3375 Koapaka Street, Suite I-560 Honolulu, Hawaii 96819.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>ClinicalTrials.gov</DataBankName><AccessionNumberList><AccessionNumber>NCT02362477</AccessionNumber><AccessionNumber>NCT00879255</AccessionNumber></AccessionNumberList></DataBank></DataBankList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Mil Med</MedlineTA><NlmUniqueID>2984771R</NlmUniqueID><ISSNLinking>0026-4075</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Mil Med. 2020 Sep 18;185(9-10):e1376-e1377</RefSource><PMID Version="1">32350536</PMID></CommentsCorrections></CommentsCorrectionsList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>2</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>2</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>2</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32077948</ArticleId><ArticleId IdType="pii">5741353</ArticleId><ArticleId IdType="doi">10.1093/milmed/usz474</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Californie</li><li>Hawaï</li></region></list><tree><country name="États-Unis"><region name="Californie"><name sortKey="Glassman, Lisa H" sort="Glassman, Lisa H" uniqKey="Glassman L" first="Lisa H" last="Glassman">Lisa H. Glassman</name></region><name sortKey="Glassman, Lisa H" sort="Glassman, Lisa H" uniqKey="Glassman L" first="Lisa H" last="Glassman">Lisa H. Glassman</name><name sortKey="Mackintosh, Margaret Anne" sort="Mackintosh, Margaret Anne" uniqKey="Mackintosh M" first="Margaret-Anne" last="Mackintosh">Margaret-Anne Mackintosh</name><name sortKey="Morland, Leslie A" sort="Morland, Leslie A" uniqKey="Morland L" first="Leslie A" last="Morland">Leslie A. Morland</name><name sortKey="Morland, Leslie A" sort="Morland, Leslie A" uniqKey="Morland L" first="Leslie A" last="Morland">Leslie A. Morland</name><name sortKey="Morland, Leslie A" sort="Morland, Leslie A" uniqKey="Morland L" first="Leslie A" last="Morland">Leslie A. Morland</name><name sortKey="Morland, Leslie A" sort="Morland, Leslie A" uniqKey="Morland L" first="Leslie A" last="Morland">Leslie A. Morland</name><name sortKey="Walter, Kristen H" sort="Walter, Kristen H" uniqKey="Walter K" first="Kristen H" last="Walter">Kristen H. Walter</name><name sortKey="Wells, Stephanie Y" sort="Wells, Stephanie Y" uniqKey="Wells S" first="Stephanie Y" last="Wells">Stephanie Y. Wells</name><name sortKey="Wells, Stephanie Y" sort="Wells, Stephanie Y" uniqKey="Wells S" first="Stephanie Y" last="Wells">Stephanie Y. Wells</name><name sortKey="Wells, Stephanie Y" sort="Wells, Stephanie Y" uniqKey="Wells S" first="Stephanie Y" last="Wells">Stephanie Y. Wells</name><name sortKey="Wickramasinghe, Induni" sort="Wickramasinghe, Induni" uniqKey="Wickramasinghe I" first="Induni" last="Wickramasinghe">Induni Wickramasinghe</name><name sortKey="Wickramasinghe, Induni" sort="Wickramasinghe, Induni" uniqKey="Wickramasinghe I" first="Induni" last="Wickramasinghe">Induni Wickramasinghe</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/WillowV1/Data/Main/Exploration
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|texte= Predictors of Quality of Life Following Cognitive Processing Therapy Among Women and Men With Post-Traumatic Stress Disorder.
}}
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