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9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (goat willow).

Identifieur interne : 001449 ( Main/Corpus ); précédent : 001448; suivant : 001450

9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (goat willow).

Auteurs : Mudasir A. Tantry ; Saba Shah ; Mohammad Y. Dar ; Mohammad M. Mir ; Khalid Ghazanfar ; Faheem A. Sheikh ; Mohammad A. Khuroo ; Seema Akbar

Source :

RBID : pubmed:22401597

English descriptors

Abstract

Chemical investigation of low polar solvent extract of Salix caprea through chromatographic techniques led to the isolation of new triterpene as 1α,3β,25-trihydroxy-9(11)-ene-16-one-9,10-seco-9,19-cyclolanostane (1) along with fatty alcohols. The structure of compound 1 was established by IR, HRESI/MS and NMR including 1D and 2D experiments. The compound 1 showed moderate in vitro antiplasmodial activity.

DOI: 10.1080/14786419.2012.665912
PubMed: 22401597

Links to Exploration step

pubmed:22401597

Le document en format XML

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<title xml:lang="en">9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (goat willow).</title>
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<name sortKey="Tantry, Mudasir A" sort="Tantry, Mudasir A" uniqKey="Tantry M" first="Mudasir A" last="Tantry">Mudasir A. Tantry</name>
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<name sortKey="Shah, Saba" sort="Shah, Saba" uniqKey="Shah S" first="Saba" last="Shah">Saba Shah</name>
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<name sortKey="Dar, Mohammad Y" sort="Dar, Mohammad Y" uniqKey="Dar M" first="Mohammad Y" last="Dar">Mohammad Y. Dar</name>
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<name sortKey="Mir, Mohammad M" sort="Mir, Mohammad M" uniqKey="Mir M" first="Mohammad M" last="Mir">Mohammad M. Mir</name>
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<name sortKey="Ghazanfar, Khalid" sort="Ghazanfar, Khalid" uniqKey="Ghazanfar K" first="Khalid" last="Ghazanfar">Khalid Ghazanfar</name>
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<term>Chloroform (MeSH)</term>
<term>Chromatography (MeSH)</term>
<term>Flowers (chemistry)</term>
<term>Magnetic Resonance Spectroscopy (MeSH)</term>
<term>Microbial Sensitivity Tests (MeSH)</term>
<term>Molecular Structure (MeSH)</term>
<term>Plant Extracts (analysis)</term>
<term>Plant Extracts (isolation & purification)</term>
<term>Plant Extracts (pharmacology)</term>
<term>Plasmodium falciparum (drug effects)</term>
<term>Salix (chemistry)</term>
<term>Triterpenes (analysis)</term>
<term>Triterpenes (isolation & purification)</term>
<term>Triterpenes (pharmacology)</term>
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<div type="abstract" xml:lang="en">Chemical investigation of low polar solvent extract of Salix caprea through chromatographic techniques led to the isolation of new triterpene as 1α,3β,25-trihydroxy-9(11)-ene-16-one-9,10-seco-9,19-cyclolanostane (1) along with fatty alcohols. The structure of compound 1 was established by IR, HRESI/MS and NMR including 1D and 2D experiments. The compound 1 showed moderate in vitro antiplasmodial activity.</div>
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<ArticleTitle>9,10-seco-9,19-cyclolanostane triterpene from Salix caprea L. (goat willow).</ArticleTitle>
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