Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees.
Identifieur interne : 000816 ( Main/Corpus ); précédent : 000815; suivant : 000817Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees.
Auteurs : Amanda L A. Mohr ; Melissa Friscia ; Jillian K. Yeakel ; Barry K. LoganSource :
- Forensic science international [ 1872-6283 ] ; 2018.
English descriptors
- KwdEn :
- Central Nervous System Stimulants (analysis), Dancing (MeSH), Designer Drugs (analysis), Female (MeSH), Florida (MeSH), Hallucinogens (analysis), Humans (MeSH), Male (MeSH), Music (MeSH), Saliva (chemistry), Substance Abuse Detection (MeSH), Substance-Related Disorders (diagnosis), Surveys and Questionnaires (MeSH), Young Adult (MeSH).
- MESH :
- chemical , analysis : Central Nervous System Stimulants, Designer Drugs, Hallucinogens.
- chemistry : Saliva.
- diagnosis : Substance-Related Disorders.
- Dancing, Female, Florida, Humans, Male, Music, Substance Abuse Detection, Surveys and Questionnaires, Young Adult.
Abstract
Novel psychoactive substances (NPS), often characterized as unregulated psychoactive compounds designed to circumvent existing legislation, have become mainstream on the illicit drug market. Because of their physical and mind-altering properties, NPS may be deliberately or inadvertently ingested at electronic dance music (EDM) festivals to enhance the attendees' appreciation of the music and overall experience. Their widespread use at EDM festivals have been well documented and several adverse events and fatalities associated with NPS ingestion have been reported in the United States. The diversity and rapid turnover in the prevalence of any particular NPS at any given point of time has created several challenges for public health officials, law enforcement, and forensic science communities. Epidemiological studies are often published long after drugs have cycled through the peak of their popularity with users and the scope of testing frequently failing to detect, identify or report the most recently available drugs. The aims of the study included discovering emerging NPS, ascertaining their overall prevalence and determining patterns of use and trends within this targeted population. Over the course of two years, biological samples were collected from 396 (126 blood samples; 227 urine samples; and 384 oral fluid samples) EDM festival attendees. Additionally, survey data regarding prescription and recreational drug use within the last week were collected with follow-up questions related to what substance(s) the person had ingested, amount taken, when the substance was last taken and perceived effects. All biological samples were screened and subsequently confirmed and/or quantified, when appropriate. In response to survey questions, 72% of the participants reported using a recreational drug or medicinal substance within the last week. Users most commonly reported using marijuana and alcohol, followed by "Molly" and cocaine. Of the 396 individuals tested, approximately 75% of the population was positive in at least one biological specimen for drugs and/or alcohol. Of those positive samples, 36% were confirmed to contain one or more NPS and/or 3,4-methylenedioxy-methamphetamine (MDMA). High rates of turnover and spikes in popularity related to NPS are supported by samples confirming positive for alpha-PVP in 2014, however, one year later not a single case was positive for alpha-PVP, and instead increasing numbers of subjects were positive for ethylone.
DOI: 10.1016/j.forsciint.2017.11.017
PubMed: 29216523
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pubmed:29216523Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees.</title><author><name sortKey="Mohr, Amanda L A" sort="Mohr, Amanda L A" uniqKey="Mohr A" first="Amanda L A" last="Mohr">Amanda L A. Mohr</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Friscia, Melissa" sort="Friscia, Melissa" uniqKey="Friscia M" first="Melissa" last="Friscia">Melissa Friscia</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Yeakel, Jillian K" sort="Yeakel, Jillian K" uniqKey="Yeakel J" first="Jillian K" last="Yeakel">Jillian K. Yeakel</name><affiliation><nlm:affiliation>Lehigh Valley Toxicology, 3864 Courtney St. Suite 150, Bethlehem, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Logan, Barry K" sort="Logan, Barry K" uniqKey="Logan B" first="Barry K" last="Logan">Barry K. Logan</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States; NMS Labs, 3701 Welsh Rd, Willow Grove, PA, United States. Electronic address: barry.logan@nmslabs.com.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2018">2018</date><idno type="RBID">pubmed:29216523</idno><idno type="pmid">29216523</idno><idno type="doi">10.1016/j.forsciint.2017.11.017</idno><idno type="wicri:Area/Main/Corpus">000816</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000816</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees.</title><author><name sortKey="Mohr, Amanda L A" sort="Mohr, Amanda L A" uniqKey="Mohr A" first="Amanda L A" last="Mohr">Amanda L A. Mohr</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Friscia, Melissa" sort="Friscia, Melissa" uniqKey="Friscia M" first="Melissa" last="Friscia">Melissa Friscia</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Yeakel, Jillian K" sort="Yeakel, Jillian K" uniqKey="Yeakel J" first="Jillian K" last="Yeakel">Jillian K. Yeakel</name><affiliation><nlm:affiliation>Lehigh Valley Toxicology, 3864 Courtney St. Suite 150, Bethlehem, PA, United States.</nlm:affiliation></affiliation></author><author><name sortKey="Logan, Barry K" sort="Logan, Barry K" uniqKey="Logan B" first="Barry K" last="Logan">Barry K. Logan</name><affiliation><nlm:affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States; NMS Labs, 3701 Welsh Rd, Willow Grove, PA, United States. Electronic address: barry.logan@nmslabs.com.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Forensic science international</title><idno type="eISSN">1872-6283</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Central Nervous System Stimulants (analysis)</term><term>Dancing (MeSH)</term><term>Designer Drugs (analysis)</term><term>Female (MeSH)</term><term>Florida (MeSH)</term><term>Hallucinogens (analysis)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Music (MeSH)</term><term>Saliva (chemistry)</term><term>Substance Abuse Detection (MeSH)</term><term>Substance-Related Disorders (diagnosis)</term><term>Surveys and Questionnaires (MeSH)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Central Nervous System Stimulants</term><term>Designer Drugs</term><term>Hallucinogens</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Substance-Related Disorders</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Dancing</term><term>Female</term><term>Florida</term><term>Humans</term><term>Male</term><term>Music</term><term>Substance Abuse Detection</term><term>Surveys and Questionnaires</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Novel psychoactive substances (NPS), often characterized as unregulated psychoactive compounds designed to circumvent existing legislation, have become mainstream on the illicit drug market. Because of their physical and mind-altering properties, NPS may be deliberately or inadvertently ingested at electronic dance music (EDM) festivals to enhance the attendees' appreciation of the music and overall experience. Their widespread use at EDM festivals have been well documented and several adverse events and fatalities associated with NPS ingestion have been reported in the United States. The diversity and rapid turnover in the prevalence of any particular NPS at any given point of time has created several challenges for public health officials, law enforcement, and forensic science communities. Epidemiological studies are often published long after drugs have cycled through the peak of their popularity with users and the scope of testing frequently failing to detect, identify or report the most recently available drugs. The aims of the study included discovering emerging NPS, ascertaining their overall prevalence and determining patterns of use and trends within this targeted population. Over the course of two years, biological samples were collected from 396 (126 blood samples; 227 urine samples; and 384 oral fluid samples) EDM festival attendees. Additionally, survey data regarding prescription and recreational drug use within the last week were collected with follow-up questions related to what substance(s) the person had ingested, amount taken, when the substance was last taken and perceived effects. All biological samples were screened and subsequently confirmed and/or quantified, when appropriate. In response to survey questions, 72% of the participants reported using a recreational drug or medicinal substance within the last week. Users most commonly reported using marijuana and alcohol, followed by "Molly" and cocaine. Of the 396 individuals tested, approximately 75% of the population was positive in at least one biological specimen for drugs and/or alcohol. Of those positive samples, 36% were confirmed to contain one or more NPS and/or 3,4-methylenedioxy-methamphetamine (MDMA). High rates of turnover and spikes in popularity related to NPS are supported by samples confirming positive for alpha-PVP in 2014, however, one year later not a single case was positive for alpha-PVP, and instead increasing numbers of subjects were positive for ethylone.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29216523</PMID><DateCompleted><Year>2018</Year><Month>05</Month><Day>30</Day></DateCompleted><DateRevised><Year>2018</Year><Month>05</Month><Day>30</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-6283</ISSN><JournalIssue CitedMedium="Internet"><Volume>282</Volume><PubDate><Year>2018</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Forensic science international</Title><ISOAbbreviation>Forensic Sci Int</ISOAbbreviation></Journal><ArticleTitle>Use of synthetic stimulants and hallucinogens in a cohort of electronic dance music festival attendees.</ArticleTitle><Pagination><MedlinePgn>168-178</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0379-0738(17)30475-9</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.forsciint.2017.11.017</ELocationID><Abstract><AbstractText>Novel psychoactive substances (NPS), often characterized as unregulated psychoactive compounds designed to circumvent existing legislation, have become mainstream on the illicit drug market. Because of their physical and mind-altering properties, NPS may be deliberately or inadvertently ingested at electronic dance music (EDM) festivals to enhance the attendees' appreciation of the music and overall experience. Their widespread use at EDM festivals have been well documented and several adverse events and fatalities associated with NPS ingestion have been reported in the United States. The diversity and rapid turnover in the prevalence of any particular NPS at any given point of time has created several challenges for public health officials, law enforcement, and forensic science communities. Epidemiological studies are often published long after drugs have cycled through the peak of their popularity with users and the scope of testing frequently failing to detect, identify or report the most recently available drugs. The aims of the study included discovering emerging NPS, ascertaining their overall prevalence and determining patterns of use and trends within this targeted population. Over the course of two years, biological samples were collected from 396 (126 blood samples; 227 urine samples; and 384 oral fluid samples) EDM festival attendees. Additionally, survey data regarding prescription and recreational drug use within the last week were collected with follow-up questions related to what substance(s) the person had ingested, amount taken, when the substance was last taken and perceived effects. All biological samples were screened and subsequently confirmed and/or quantified, when appropriate. In response to survey questions, 72% of the participants reported using a recreational drug or medicinal substance within the last week. Users most commonly reported using marijuana and alcohol, followed by "Molly" and cocaine. Of the 396 individuals tested, approximately 75% of the population was positive in at least one biological specimen for drugs and/or alcohol. Of those positive samples, 36% were confirmed to contain one or more NPS and/or 3,4-methylenedioxy-methamphetamine (MDMA). High rates of turnover and spikes in popularity related to NPS are supported by samples confirming positive for alpha-PVP in 2014, however, one year later not a single case was positive for alpha-PVP, and instead increasing numbers of subjects were positive for ethylone.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier B.V. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mohr</LastName><ForeName>Amanda L A</ForeName><Initials>ALA</Initials><AffiliationInfo><Affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Friscia</LastName><ForeName>Melissa</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yeakel</LastName><ForeName>Jillian K</ForeName><Initials>JK</Initials><AffiliationInfo><Affiliation>Lehigh Valley Toxicology, 3864 Courtney St. Suite 150, Bethlehem, PA, United States.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Logan</LastName><ForeName>Barry K</ForeName><Initials>BK</Initials><AffiliationInfo><Affiliation>The Center for Forensic Science Research and Education (CFSRE), 2300 Stratford Ave, Willow Grove, PA, United States; NMS Labs, 3701 Welsh Rd, Willow Grove, PA, United States. Electronic address: barry.logan@nmslabs.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>11</Month><Day>21</Day></ArticleDate></Article><MedlineJournalInfo><Country>Ireland</Country><MedlineTA>Forensic Sci Int</MedlineTA><NlmUniqueID>7902034</NlmUniqueID><ISSNLinking>0379-0738</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000697">Central Nervous System Stimulants</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015198">Designer Drugs</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006213">Hallucinogens</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000697" MajorTopicYN="N">Central Nervous System Stimulants</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003615" MajorTopicYN="N">Dancing</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015198" MajorTopicYN="N">Designer Drugs</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005431" MajorTopicYN="N">Florida</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006213" MajorTopicYN="N">Hallucinogens</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009146" MajorTopicYN="N">Music</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015813" MajorTopicYN="N">Substance Abuse Detection</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019966" MajorTopicYN="N">Substance-Related Disorders</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Electronic dance music festivals</Keyword><Keyword MajorTopicYN="N">NPS</Keyword><Keyword MajorTopicYN="N">Oral fluid</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2017</Year><Month>06</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2017</Year><Month>11</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2017</Year><Month>11</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>12</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2018</Year><Month>5</Month><Day>31</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>12</Month><Day>8</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">29216523</ArticleId><ArticleId IdType="pii">S0379-0738(17)30475-9</ArticleId><ArticleId IdType="doi">10.1016/j.forsciint.2017.11.017</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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