Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice.
Identifieur interne : 000271 ( Main/Corpus ); précédent : 000270; suivant : 000272Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice.
Auteurs : Craig Haifer ; Colleen R. Kelly ; Sudarshan Paramsothy ; David Andresen ; Lito E. Papanicolas ; Genevieve L. Mckew ; Thomas J. Borody ; Michael Kamm ; Samuel P. Costello ; Jane M. Andrews ; Jakob Begun ; Hiu Tat Chan ; Susan Connor ; Simon Ghaly ; Paul Dr Johnson ; Daniel A. Lemberg ; Ramesh Paramsothy ; Andrew Redmond ; Harsha Sheorey ; David Van Der Poorten ; Rupert W. LeongSource :
- Gut [ 1468-3288 ] ; 2020.
English descriptors
- KwdEn :
- MESH :
- geographic : Australia.
- methods : Fecal Microbiota Transplantation.
- statistics & numerical data : Health Facilities.
- therapy : Clostridium Infections.
- Consensus, Donor Selection, Female, Humans, Male, Practice Guidelines as Topic, Treatment Outcome.
Abstract
OBJECTIVE
Faecal microbiota transplantation (FMT) has proved to be an extremely effective treatment for recurrent
DESIGN
For these consensus statements, a 24-member multidisciplinary working group voted online and then convened in-person, using a modified Delphi approach to formulate and refine a series of recommendations based on best evidence and expert opinion. Invitations to participate were directed to Australian experts, with an international delegate assisting the development. The following issues regarding the use of FMT in clinical practice were addressed: donor selection and screening, clinical indications, requirements of FMT centres and future directions. Evidence was rated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system.
RESULTS
Consensus was reached on 27 statements to provide guidance on best practice in FMT. These include: (1) minimum standards for donor screening with recommended clinical selection criteria, blood and stool testing; (2) accepted routes of administration; (3) clinical indications; (4) minimum standards for FMT production and requirements for treatment facilities acknowledging distinction between single-site centres (eg, hospital-based) and stool banks; and (5) recommendations on future research and product development.
CONCLUSIONS
These FMT consensus statements provide comprehensive recommendations around the production and use of FMT in clinical practice with relevance to clinicians, researchers and policy makers.
DOI: 10.1136/gutjnl-2019-320260
PubMed: 32047093
Links to Exploration step
pubmed:32047093Le document en format XML
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Kelly</name><affiliation><nlm:affiliation>Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Paramsothy, Sudarshan" sort="Paramsothy, Sudarshan" uniqKey="Paramsothy S" first="Sudarshan" last="Paramsothy">Sudarshan Paramsothy</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Andresen, David" sort="Andresen, David" uniqKey="Andresen D" first="David" last="Andresen">David Andresen</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Papanicolas, Lito E" sort="Papanicolas, Lito E" uniqKey="Papanicolas L" first="Lito E" last="Papanicolas">Lito E. Papanicolas</name><affiliation><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Mckew, Genevieve L" sort="Mckew, Genevieve L" uniqKey="Mckew G" first="Genevieve L" last="Mckew">Genevieve L. Mckew</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Borody, Thomas J" sort="Borody, Thomas J" uniqKey="Borody T" first="Thomas J" last="Borody">Thomas J. 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Costello</name><affiliation><nlm:affiliation>The Queen Elizabeth Hospital, Woodville, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>BiomeBank, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Andrews, Jane M" sort="Andrews, Jane M" uniqKey="Andrews J" first="Jane M" last="Andrews">Jane M. Andrews</name><affiliation><nlm:affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>The University of Adelaide, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Begun, Jakob" sort="Begun, Jakob" uniqKey="Begun J" first="Jakob" last="Begun">Jakob Begun</name><affiliation><nlm:affiliation>The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Mater Hospital Brisbane, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Chan, Hiu Tat" sort="Chan, Hiu Tat" uniqKey="Chan H" first="Hiu Tat" last="Chan">Hiu Tat Chan</name><affiliation><nlm:affiliation>VCS Pathology, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Connor, Susan" sort="Connor, Susan" uniqKey="Connor S" first="Susan" last="Connor">Susan Connor</name><affiliation><nlm:affiliation>Liverpool Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Ghaly, Simon" sort="Ghaly, Simon" uniqKey="Ghaly S" first="Simon" last="Ghaly">Simon Ghaly</name><affiliation><nlm:affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Paul Dr" sort="Johnson, Paul Dr" uniqKey="Johnson P" first="Paul Dr" last="Johnson">Paul Dr Johnson</name><affiliation><nlm:affiliation>The University of Melbourne, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Austin Hospital, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lemberg, Daniel A" sort="Lemberg, Daniel A" uniqKey="Lemberg D" first="Daniel A" last="Lemberg">Daniel A. Lemberg</name><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Sydney Children's Hospital Randwick, Randwick, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Paramsothy, Ramesh" sort="Paramsothy, Ramesh" uniqKey="Paramsothy R" first="Ramesh" last="Paramsothy">Ramesh Paramsothy</name><affiliation><nlm:affiliation>Blacktown Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Redmond, Andrew" sort="Redmond, Andrew" uniqKey="Redmond A" first="Andrew" last="Redmond">Andrew Redmond</name><affiliation><nlm:affiliation>The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Sheorey, Harsha" sort="Sheorey, Harsha" uniqKey="Sheorey H" first="Harsha" last="Sheorey">Harsha Sheorey</name><affiliation><nlm:affiliation>St Vincent's Hospital, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Poorten, David" sort="Van Der Poorten, David" uniqKey="Van Der Poorten D" first="David" last="Van Der Poorten">David Van Der Poorten</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Westmead Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Leong, Rupert W" sort="Leong, Rupert W" uniqKey="Leong R" first="Rupert W" last="Leong">Rupert W. Leong</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia rupertleong@outlook.com.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32047093</idno><idno type="pmid">32047093</idno><idno type="doi">10.1136/gutjnl-2019-320260</idno><idno type="wicri:Area/Main/Corpus">000271</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000271</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice.</title><author><name sortKey="Haifer, Craig" sort="Haifer, Craig" uniqKey="Haifer C" first="Craig" last="Haifer">Craig Haifer</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Kelly, Colleen R" sort="Kelly, Colleen R" uniqKey="Kelly C" first="Colleen R" last="Kelly">Colleen R. Kelly</name><affiliation><nlm:affiliation>Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Paramsothy, Sudarshan" sort="Paramsothy, Sudarshan" uniqKey="Paramsothy S" first="Sudarshan" last="Paramsothy">Sudarshan Paramsothy</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Andresen, David" sort="Andresen, David" uniqKey="Andresen D" first="David" last="Andresen">David Andresen</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Papanicolas, Lito E" sort="Papanicolas, Lito E" uniqKey="Papanicolas L" first="Lito E" last="Papanicolas">Lito E. Papanicolas</name><affiliation><nlm:affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Mckew, Genevieve L" sort="Mckew, Genevieve L" uniqKey="Mckew G" first="Genevieve L" last="Mckew">Genevieve L. Mckew</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Borody, Thomas J" sort="Borody, Thomas J" uniqKey="Borody T" first="Thomas J" last="Borody">Thomas J. Borody</name><affiliation><nlm:affiliation>Centre for Digestive Diseases, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Kamm, Michael" sort="Kamm, Michael" uniqKey="Kamm M" first="Michael" last="Kamm">Michael Kamm</name><affiliation><nlm:affiliation>St Vincent's Hospital, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>The University of Melbourne, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Costello, Samuel P" sort="Costello, Samuel P" uniqKey="Costello S" first="Samuel P" last="Costello">Samuel P. Costello</name><affiliation><nlm:affiliation>The Queen Elizabeth Hospital, Woodville, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>BiomeBank, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Andrews, Jane M" sort="Andrews, Jane M" uniqKey="Andrews J" first="Jane M" last="Andrews">Jane M. Andrews</name><affiliation><nlm:affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>The University of Adelaide, Adelaide, South Australia, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Begun, Jakob" sort="Begun, Jakob" uniqKey="Begun J" first="Jakob" last="Begun">Jakob Begun</name><affiliation><nlm:affiliation>The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Mater Hospital Brisbane, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Chan, Hiu Tat" sort="Chan, Hiu Tat" uniqKey="Chan H" first="Hiu Tat" last="Chan">Hiu Tat Chan</name><affiliation><nlm:affiliation>VCS Pathology, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Connor, Susan" sort="Connor, Susan" uniqKey="Connor S" first="Susan" last="Connor">Susan Connor</name><affiliation><nlm:affiliation>Liverpool Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Ghaly, Simon" sort="Ghaly, Simon" uniqKey="Ghaly S" first="Simon" last="Ghaly">Simon Ghaly</name><affiliation><nlm:affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Johnson, Paul Dr" sort="Johnson, Paul Dr" uniqKey="Johnson P" first="Paul Dr" last="Johnson">Paul Dr Johnson</name><affiliation><nlm:affiliation>The University of Melbourne, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Austin Hospital, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Lemberg, Daniel A" sort="Lemberg, Daniel A" uniqKey="Lemberg D" first="Daniel A" last="Lemberg">Daniel A. Lemberg</name><affiliation><nlm:affiliation>University of New South Wales, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Sydney Children's Hospital Randwick, Randwick, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Paramsothy, Ramesh" sort="Paramsothy, Ramesh" uniqKey="Paramsothy R" first="Ramesh" last="Paramsothy">Ramesh Paramsothy</name><affiliation><nlm:affiliation>Blacktown Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Redmond, Andrew" sort="Redmond, Andrew" uniqKey="Redmond A" first="Andrew" last="Redmond">Andrew Redmond</name><affiliation><nlm:affiliation>The University of Queensland, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Sheorey, Harsha" sort="Sheorey, Harsha" uniqKey="Sheorey H" first="Harsha" last="Sheorey">Harsha Sheorey</name><affiliation><nlm:affiliation>St Vincent's Hospital, Melbourne, Victoria, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Van Der Poorten, David" sort="Van Der Poorten, David" uniqKey="Van Der Poorten D" first="David" last="Van Der Poorten">David Van Der Poorten</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Westmead Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author><author><name sortKey="Leong, Rupert W" sort="Leong, Rupert W" uniqKey="Leong R" first="Rupert W" last="Leong">Rupert W. Leong</name><affiliation><nlm:affiliation>The University of Sydney, Sydney, New South Wales, Australia rupertleong@outlook.com.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Gut</title><idno type="eISSN">1468-3288</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Australia (MeSH)</term><term>Clostridium Infections (therapy)</term><term>Consensus (MeSH)</term><term>Donor Selection (MeSH)</term><term>Fecal Microbiota Transplantation (methods)</term><term>Female (MeSH)</term><term>Health Facilities (statistics & numerical data)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Practice Guidelines as Topic (MeSH)</term><term>Treatment Outcome (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Australia</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Fecal Microbiota Transplantation</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Health Facilities</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Clostridium Infections</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Consensus</term><term>Donor Selection</term><term>Female</term><term>Humans</term><term>Male</term><term>Practice Guidelines as Topic</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>Faecal microbiota transplantation (FMT) has proved to be an extremely effective treatment for recurrent </p></div><div type="abstract" xml:lang="en"><p><b>DESIGN</b></p><p>For these consensus statements, a 24-member multidisciplinary working group voted online and then convened in-person, using a modified Delphi approach to formulate and refine a series of recommendations based on best evidence and expert opinion. Invitations to participate were directed to Australian experts, with an international delegate assisting the development. The following issues regarding the use of FMT in clinical practice were addressed: donor selection and screening, clinical indications, requirements of FMT centres and future directions. Evidence was rated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Consensus was reached on 27 statements to provide guidance on best practice in FMT. These include: (1) minimum standards for donor screening with recommended clinical selection criteria, blood and stool testing; (2) accepted routes of administration; (3) clinical indications; (4) minimum standards for FMT production and requirements for treatment facilities acknowledging distinction between single-site centres (eg, hospital-based) and stool banks; and (5) recommendations on future research and product development.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>These FMT consensus statements provide comprehensive recommendations around the production and use of FMT in clinical practice with relevance to clinicians, researchers and policy makers.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32047093</PMID><DateCompleted><Year>2020</Year><Month>11</Month><Day>03</Day></DateCompleted><DateRevised><Year>2020</Year><Month>11</Month><Day>03</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1468-3288</ISSN><JournalIssue CitedMedium="Internet"><Volume>69</Volume><Issue>5</Issue><PubDate><Year>2020</Year><Month>05</Month></PubDate></JournalIssue><Title>Gut</Title><ISOAbbreviation>Gut</ISOAbbreviation></Journal><ArticleTitle>Australian consensus statements for the regulation, production and use of faecal microbiota transplantation in clinical practice.</ArticleTitle><Pagination><MedlinePgn>801-810</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1136/gutjnl-2019-320260</ELocationID><Abstract><AbstractText Label="OBJECTIVE">Faecal microbiota transplantation (FMT) has proved to be an extremely effective treatment for recurrent <i>Clostridioides difficile</i> infection, and there is interest in its potential application in other gastrointestinal and systemic diseases. However, the recent death and episode of septicaemia following FMT highlights the need for further appraisal and guidelines on donor evaluation, production standards, treatment facilities and acceptable clinical indications.</AbstractText><AbstractText Label="DESIGN">For these consensus statements, a 24-member multidisciplinary working group voted online and then convened in-person, using a modified Delphi approach to formulate and refine a series of recommendations based on best evidence and expert opinion. Invitations to participate were directed to Australian experts, with an international delegate assisting the development. The following issues regarding the use of FMT in clinical practice were addressed: donor selection and screening, clinical indications, requirements of FMT centres and future directions. Evidence was rated using the GRADE (Grading of Recommendations Assessment, Development and Evaluation) system.</AbstractText><AbstractText Label="RESULTS">Consensus was reached on 27 statements to provide guidance on best practice in FMT. These include: (1) minimum standards for donor screening with recommended clinical selection criteria, blood and stool testing; (2) accepted routes of administration; (3) clinical indications; (4) minimum standards for FMT production and requirements for treatment facilities acknowledging distinction between single-site centres (eg, hospital-based) and stool banks; and (5) recommendations on future research and product development.</AbstractText><AbstractText Label="CONCLUSIONS">These FMT consensus statements provide comprehensive recommendations around the production and use of FMT in clinical practice with relevance to clinicians, researchers and policy makers.</AbstractText><CopyrightInformation>© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Haifer</LastName><ForeName>Craig</ForeName><Initials>C</Initials><Identifier Source="ORCID">0000-0002-3675-6550</Identifier><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kelly</LastName><ForeName>Colleen R</ForeName><Initials>CR</Initials><AffiliationInfo><Affiliation>Warren Alpert Medical School, Brown University, Providence, Rhode Island, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paramsothy</LastName><ForeName>Sudarshan</ForeName><Initials>S</Initials><Identifier Source="ORCID">0000-0002-9097-6028</Identifier><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andresen</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Papanicolas</LastName><ForeName>Lito E</ForeName><Initials>LE</Initials><Identifier Source="ORCID">0000-0002-5838-7274</Identifier><AffiliationInfo><Affiliation>South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McKew</LastName><ForeName>Genevieve L</ForeName><Initials>GL</Initials><Identifier Source="ORCID">0000-0002-5238-9260</Identifier><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Borody</LastName><ForeName>Thomas J</ForeName><Initials>TJ</Initials><Identifier Source="ORCID">0000-0002-0519-4698</Identifier><AffiliationInfo><Affiliation>Centre for Digestive Diseases, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kamm</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>St Vincent's Hospital, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The University of Melbourne, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Costello</LastName><ForeName>Samuel P</ForeName><Initials>SP</Initials><Identifier Source="ORCID">0000-0002-2857-1812</Identifier><AffiliationInfo><Affiliation>The Queen Elizabeth Hospital, Woodville, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>BiomeBank, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Andrews</LastName><ForeName>Jane M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>Royal Adelaide Hospital, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>The University of Adelaide, Adelaide, South Australia, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Begun</LastName><ForeName>Jakob</ForeName><Initials>J</Initials><Identifier Source="ORCID">0000-0001-5256-7672</Identifier><AffiliationInfo><Affiliation>The University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Mater Hospital Brisbane, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chan</LastName><ForeName>Hiu Tat</ForeName><Initials>HT</Initials><AffiliationInfo><Affiliation>VCS Pathology, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Connor</LastName><ForeName>Susan</ForeName><Initials>S</Initials><Identifier Source="ORCID">0000-0001-5606-0270</Identifier><AffiliationInfo><Affiliation>Liverpool Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of New South Wales, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ghaly</LastName><ForeName>Simon</ForeName><Initials>S</Initials><Identifier Source="ORCID">0000-0003-2489-6430</Identifier><AffiliationInfo><Affiliation>St Vincent's Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>University of New South Wales, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Johnson</LastName><ForeName>Paul Dr</ForeName><Initials>PD</Initials><AffiliationInfo><Affiliation>The University of Melbourne, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Austin Hospital, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lemberg</LastName><ForeName>Daniel A</ForeName><Initials>DA</Initials><AffiliationInfo><Affiliation>University of New South Wales, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Sydney Children's Hospital Randwick, Randwick, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Paramsothy</LastName><ForeName>Ramesh</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Blacktown Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Redmond</LastName><ForeName>Andrew</ForeName><Initials>A</Initials><Identifier Source="ORCID">0000-0002-1125-5362</Identifier><AffiliationInfo><Affiliation>The University of Queensland, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sheorey</LastName><ForeName>Harsha</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>St Vincent's Hospital, Melbourne, Victoria, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Poorten</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Westmead Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leong</LastName><ForeName>Rupert W</ForeName><Initials>RW</Initials><Identifier Source="ORCID">0000-0001-5944-3488</Identifier><AffiliationInfo><Affiliation>The University of Sydney, Sydney, New South Wales, Australia rupertleong@outlook.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Concord Repatriation General Hospital, Sydney, New South Wales, Australia.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>02</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Gut</MedlineTA><NlmUniqueID>2985108R</NlmUniqueID><ISSNLinking>0017-5749</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001315" MajorTopicYN="N" Type="Geographic">Australia</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003015" MajorTopicYN="N">Clostridium Infections</DescriptorName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032921" MajorTopicYN="N">Consensus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D046148" MajorTopicYN="N">Donor Selection</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000069467" MajorTopicYN="N">Fecal Microbiota Transplantation</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006268" MajorTopicYN="N">Health Facilities</DescriptorName><QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017410" MajorTopicYN="Y">Practice Guidelines as Topic</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Clostridioides difficile
</Keyword><Keyword MajorTopicYN="Y">FMT</Keyword><Keyword MajorTopicYN="Y">faecal microbiota transplantation</Keyword><Keyword MajorTopicYN="Y">inflammatory bowel disease</Keyword><Keyword MajorTopicYN="Y">microbiome therapeutics</Keyword><Keyword MajorTopicYN="Y">stool bank</Keyword></KeywordList><CoiStatement>Competing interests: CRK has received research support and is a site investigator for Finch Therapeutics; and is a clinical advisory board member for Openbiome. SP is a consultant for Finch Therapeutics and received speaker fees from Ferring, Janssen. TJB has interest in Redhill Biopharma, Salix and Finch Therapeutics, ResMed and GSK; has interest in the Centre for Digestive Diseases, where faecal microbiota transplantation is a treatment option for patients, and has patents in this field. MK has received speaker fees, research funding, educational support or honoraria for advisory board participation from Ferring, AbbVie, Janssen, Takeda and received research support from AbbVie. SPC has received speaker fees from Shire, Ferring, Microbiotica, Pfizer and Janssen; and is a shareholder in BiomeBank. JMA has received speaker fees, research funding, educational support or honoraria for advisory board participation from Abbott, AbbVie, Allergan, Anatara, AstraZeneca, Bayer, Celegene, Ferring, Gilead, Hospira, Immuninc, ImmunsanT, Janssen, MSD, Nestle, Progenity, Pfizer, Shire, Takeda, Vifor, Royal Adelaide Research Fund and The Hospital Research Fund. JB has received speaker fees, research funding, educational support or honoraria for advisory board participation from Janssen, Takeda, AbbVie, Celgene, Ferring, Pfizer, Anatara, Microba, Shire and Progenity. SC has received speaker fees, research funding, educational support or honoraria for advisory board participation from AbbVie, Aspen/Orphan, Celgene, Ferring, Gilead, Janssen, MSD, Pfizer, Shire, Takeda and Vifor. SG has received speaker fees, research funding, educational support or honoraria for advisory board participation from Janssen Cilag, Shire, Takeda, Ferring and Pfizer and AbbVie. DAL has received speaker fees, research funding, educational support or honoraria for advisory board participation from Nutricia, Nestle, Janssen, AbbVie. RP has received speaker fees or research support from Janssen, Aspen, Pfizer, Abbvie and Takeda. RWL reports advisory board fees from AbbVie, Aspen, Celgene, Ferring, Gilead, Hospira, Janssen, MSD, Novartis, Pfizer, and Takeda; research fees from Gastrointestinal Society of Australia (GESA), Endochoice, Janssen, National Health and Medical Research Council of Australia, Shire, and Takeda; and speaker fees from Emerge Health, Ferring, Janssen, Shire, and Takeda.</CoiStatement></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>11</Month><Day>12</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>12</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>12</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>11</Month><Day>4</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>2</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32047093</ArticleId><ArticleId IdType="pii">gutjnl-2019-320260</ArticleId><ArticleId IdType="doi">10.1136/gutjnl-2019-320260</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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