A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda).
Identifieur interne : 000302 ( Ncbi/Curation ); précédent : 000301; suivant : 000303A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda).
Auteurs : Charline Pressanti [France] ; Maxence Delverdier ; Xavier Iriart ; Frédérique Morcel ; Marie-Christine CadierguesSource :
- Veterinary dermatology [ 1365-3164 ] ; 2012.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antifungal Agents.
- classification : Trichophyton.
- drug therapy : Dermatomycoses.
- microbiology : Dermatomycoses, Tinea.
- veterinary : Dermatomycoses, Tinea.
- Animals, Animals, Zoo, Foxes, Male.
Abstract
A 2-year-old male fennec fox presented with a 4 month history of nonpruritic, crusty skin lesions on the forehead, the pinnae and the tail tip. Initial investigations, including routine haematology, biochemistry profile, multiple skin scrapings, trichoscopic examination, Wood's lamp examination and fungal culture, failed to reveal any abnormalities. Histopathological examination of a first set of skin biopsies showed an interface dermatitis pattern, with lymphocyte infiltration in the basal layer, a significant lymphocytic exocytosis and occasional apoptotic basal epidermal keratinocytes; periodic acid Schiff stain did not reveal any fungal elements. On further biopsies, there was a pustular neutrophilic dermatitis, with numerous crusts containing high numbers of arthrospores and fungal hyphae. Trichophyton mentagrophytes infection was confirmed on fungal culture and PCR. The fennec fox received oral itraconazole (5 mg/kg once daily for 6 weeks) combined with a miconazole and chlorhexidine shampoo applied on affected areas once weekly, followed with an enilconazole dip. The fox improved dramatically, and a fungal culture performed at 6 weeks was negative. Unfortunately, a few days later the fennec fox developed anorexia, icterus and died. To the authors' knowledge, this is the first report of Trichophyton infection in a fennec fox and, although a postmortem examination was not performed, this is possibly the first report of fatal acute liver failure associated with itraconazole in a canid.
DOI: 10.1111/j.1365-3164.2012.01077.x
PubMed: 22822716
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000117
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000117
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000117
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000302
Links to Exploration step
pubmed:22822716Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda).</title><author><name sortKey="Pressanti, Charline" sort="Pressanti, Charline" uniqKey="Pressanti C" first="Charline" last="Pressanti">Charline Pressanti</name><affiliation wicri:level="3"><nlm:affiliation>INP-ENVT Toulouse veterinary school 23, chemin des Capelles, 31076 Toulouse Cedex 3, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INP-ENVT Toulouse veterinary school 23, chemin des Capelles, 31076 Toulouse Cedex 3</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Delverdier, Maxence" sort="Delverdier, Maxence" uniqKey="Delverdier M" first="Maxence" last="Delverdier">Maxence Delverdier</name></author><author><name sortKey="Iriart, Xavier" sort="Iriart, Xavier" uniqKey="Iriart X" first="Xavier" last="Iriart">Xavier Iriart</name></author><author><name sortKey="Morcel, Frederique" sort="Morcel, Frederique" uniqKey="Morcel F" first="Frédérique" last="Morcel">Frédérique Morcel</name></author><author><name sortKey="Cadiergues, Marie Christine" sort="Cadiergues, Marie Christine" uniqKey="Cadiergues M" first="Marie-Christine" last="Cadiergues">Marie-Christine Cadiergues</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:22822716</idno><idno type="pmid">22822716</idno><idno type="doi">10.1111/j.1365-3164.2012.01077.x</idno><idno type="wicri:Area/PubMed/Corpus">000117</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000117</idno><idno type="wicri:Area/PubMed/Curation">000117</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000117</idno><idno type="wicri:Area/PubMed/Checkpoint">000117</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000117</idno><idno type="wicri:Area/Ncbi/Merge">000302</idno><idno type="wicri:Area/Ncbi/Curation">000302</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda).</title><author><name sortKey="Pressanti, Charline" sort="Pressanti, Charline" uniqKey="Pressanti C" first="Charline" last="Pressanti">Charline Pressanti</name><affiliation wicri:level="3"><nlm:affiliation>INP-ENVT Toulouse veterinary school 23, chemin des Capelles, 31076 Toulouse Cedex 3, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INP-ENVT Toulouse veterinary school 23, chemin des Capelles, 31076 Toulouse Cedex 3</wicri:regionArea><placeName><region type="region" nuts="2">Occitanie (région administrative)</region><region type="old region" nuts="2">Midi-Pyrénées</region><settlement type="city">Toulouse</settlement></placeName></affiliation></author><author><name sortKey="Delverdier, Maxence" sort="Delverdier, Maxence" uniqKey="Delverdier M" first="Maxence" last="Delverdier">Maxence Delverdier</name></author><author><name sortKey="Iriart, Xavier" sort="Iriart, Xavier" uniqKey="Iriart X" first="Xavier" last="Iriart">Xavier Iriart</name></author><author><name sortKey="Morcel, Frederique" sort="Morcel, Frederique" uniqKey="Morcel F" first="Frédérique" last="Morcel">Frédérique Morcel</name></author><author><name sortKey="Cadiergues, Marie Christine" sort="Cadiergues, Marie Christine" uniqKey="Cadiergues M" first="Marie-Christine" last="Cadiergues">Marie-Christine Cadiergues</name></author></analytic><series><title level="j">Veterinary dermatology</title><idno type="eISSN">1365-3164</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Animals, Zoo</term><term>Antifungal Agents (therapeutic use)</term><term>Dermatomycoses (drug therapy)</term><term>Dermatomycoses (microbiology)</term><term>Dermatomycoses (veterinary)</term><term>Foxes</term><term>Male</term><term>Tinea (microbiology)</term><term>Tinea (veterinary)</term><term>Trichophyton (classification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antifungal Agents</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Trichophyton</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Dermatomycoses</term></keywords><keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Dermatomycoses</term><term>Tinea</term></keywords><keywords scheme="MESH" qualifier="veterinary" xml:lang="en"><term>Dermatomycoses</term><term>Tinea</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Animals, Zoo</term><term>Foxes</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A 2-year-old male fennec fox presented with a 4 month history of nonpruritic, crusty skin lesions on the forehead, the pinnae and the tail tip. Initial investigations, including routine haematology, biochemistry profile, multiple skin scrapings, trichoscopic examination, Wood's lamp examination and fungal culture, failed to reveal any abnormalities. Histopathological examination of a first set of skin biopsies showed an interface dermatitis pattern, with lymphocyte infiltration in the basal layer, a significant lymphocytic exocytosis and occasional apoptotic basal epidermal keratinocytes; periodic acid Schiff stain did not reveal any fungal elements. On further biopsies, there was a pustular neutrophilic dermatitis, with numerous crusts containing high numbers of arthrospores and fungal hyphae. Trichophyton mentagrophytes infection was confirmed on fungal culture and PCR. The fennec fox received oral itraconazole (5 mg/kg once daily for 6 weeks) combined with a miconazole and chlorhexidine shampoo applied on affected areas once weekly, followed with an enilconazole dip. The fox improved dramatically, and a fungal culture performed at 6 weeks was negative. Unfortunately, a few days later the fennec fox developed anorexia, icterus and died. To the authors' knowledge, this is the first report of Trichophyton infection in a fennec fox and, although a postmortem examination was not performed, this is possibly the first report of fatal acute liver failure associated with itraconazole in a canid.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/RenardV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000302 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000302 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Bois
|area= RenardV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:22822716
|texte= A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda).
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:22822716" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a RenardV1
| This area was generated with Dilib version V0.6.27. |  |