Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate.
Identifieur interne : 004B46 ( Main/Exploration ); précédent : 004B45; suivant : 004B47Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate.
Auteurs : M. Amoros ; E. Lurton ; J. Boustie ; L. Girre ; F. Sauvager ; M. CormierSource :
- Journal of natural products [ 0163-3864 ] ; 1994.
Descripteurs français
- KwdFr :
- ADN viral (biosynthèse), Acides caféiques (isolement et purification), Acides caféiques (pharmacologie), Antiviraux (isolement et purification), Antiviraux (pharmacologie), Herpèsvirus humain de type 1 (effets des médicaments et des substances chimiques), Herpèsvirus humain de type 1 (métabolisme), Humains (MeSH), Hybridation d'acides nucléiques (MeSH), Plantes médicinales (composition chimique), Propolis (pharmacologie), Sondes d'ADN (MeSH).
- MESH :
- biosynthèse : ADN viral.
- composition chimique : Plantes médicinales.
- effets des médicaments et des substances chimiques : Herpèsvirus humain de type 1.
- isolement et purification : Acides caféiques, Antiviraux.
- métabolisme : Herpèsvirus humain de type 1.
- pharmacologie : Acides caféiques, Antiviraux, Propolis.
- Humains, Hybridation d'acides nucléiques, Sondes d'ADN.
English descriptors
- KwdEn :
- Antiviral Agents (isolation & purification), Antiviral Agents (pharmacology), Caffeic Acids (isolation & purification), Caffeic Acids (pharmacology), DNA Probes (MeSH), DNA, Viral (biosynthesis), Herpesvirus 1, Human (drug effects), Herpesvirus 1, Human (metabolism), Humans (MeSH), Nucleic Acid Hybridization (MeSH), Plants, Medicinal (chemistry), Propolis (pharmacology).
- MESH :
- chemical , biosynthesis : DNA, Viral.
- chemical , isolation & purification : Antiviral Agents, Caffeic Acids.
- chemical , pharmacology : Antiviral Agents, Caffeic Acids, Propolis.
- chemical : DNA Probes.
- chemistry : Plants, Medicinal.
- drug effects : Herpesvirus 1, Human.
- metabolism : Herpesvirus 1, Human.
- Humans, Nucleic Acid Hybridization.
Abstract
The in vitro activity against herpes simplex virus type 1 of 3-methyl-but-2-enyl caffeate isolated from poplar buds or prepared by synthesis was investigated. Under conditions of one or multiple multiplication cycles, this compound, which is a minor constituent of propolis, was found to reduce the viral titer by 3 log10, and viral DNA synthesis by 32-fold.
DOI: 10.1021/np50107a013
PubMed: 8064297
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<author><name sortKey="Amoros, M" sort="Amoros, M" uniqKey="Amoros M" first="M" last="Amoros">M. Amoros</name>
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<author><name sortKey="Lurton, E" sort="Lurton, E" uniqKey="Lurton E" first="E" last="Lurton">E. Lurton</name>
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<author><name sortKey="Boustie, J" sort="Boustie, J" uniqKey="Boustie J" first="J" last="Boustie">J. Boustie</name>
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<author><name sortKey="Girre, L" sort="Girre, L" uniqKey="Girre L" first="L" last="Girre">L. Girre</name>
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<author><name sortKey="Sauvager, F" sort="Sauvager, F" uniqKey="Sauvager F" first="F" last="Sauvager">F. Sauvager</name>
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<author><name sortKey="Cormier, M" sort="Cormier, M" uniqKey="Cormier M" first="M" last="Cormier">M. Cormier</name>
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<term>Antiviral Agents (pharmacology)</term>
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<term>Caffeic Acids (pharmacology)</term>
<term>DNA Probes (MeSH)</term>
<term>DNA, Viral (biosynthesis)</term>
<term>Herpesvirus 1, Human (drug effects)</term>
<term>Herpesvirus 1, Human (metabolism)</term>
<term>Humans (MeSH)</term>
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<term>Acides caféiques (pharmacologie)</term>
<term>Antiviraux (isolement et purification)</term>
<term>Antiviraux (pharmacologie)</term>
<term>Herpèsvirus humain de type 1 (effets des médicaments et des substances chimiques)</term>
<term>Herpèsvirus humain de type 1 (métabolisme)</term>
<term>Humains (MeSH)</term>
<term>Hybridation d'acides nucléiques (MeSH)</term>
<term>Plantes médicinales (composition chimique)</term>
<term>Propolis (pharmacologie)</term>
<term>Sondes d'ADN (MeSH)</term>
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<term>Caffeic Acids</term>
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<term>Propolis</term>
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<term>Nucleic Acid Hybridization</term>
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<term>Hybridation d'acides nucléiques</term>
<term>Sondes d'ADN</term>
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<front><div type="abstract" xml:lang="en">The in vitro activity against herpes simplex virus type 1 of 3-methyl-but-2-enyl caffeate isolated from poplar buds or prepared by synthesis was investigated. Under conditions of one or multiple multiplication cycles, this compound, which is a minor constituent of propolis, was found to reduce the viral titer by 3 log10, and viral DNA synthesis by 32-fold.</div>
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<ArticleTitle>Comparison of the anti-herpes simplex virus activities of propolis and 3-methyl-but-2-enyl caffeate.</ArticleTitle>
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<Abstract><AbstractText>The in vitro activity against herpes simplex virus type 1 of 3-methyl-but-2-enyl caffeate isolated from poplar buds or prepared by synthesis was investigated. Under conditions of one or multiple multiplication cycles, this compound, which is a minor constituent of propolis, was found to reduce the viral titer by 3 log10, and viral DNA synthesis by 32-fold.</AbstractText>
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<name sortKey="Cormier, M" sort="Cormier, M" uniqKey="Cormier M" first="M" last="Cormier">M. Cormier</name>
<name sortKey="Girre, L" sort="Girre, L" uniqKey="Girre L" first="L" last="Girre">L. Girre</name>
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