PoplarV1, Main, Exploration, bibRecord, 001F11

A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder.

Identifieur interne : 001F11 ( Main/Exploration ); précédent : 001F10; suivant : 001F12

A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder.

Auteurs : Sue Lauder [Australie] ; Andrea Chester [Australie] ; David Castle [Australie] ; Seetal Dodd [Australie] ; Emma Gliddon [Australie] ; Lesley Berk [Australie] ; James Chamberlain [Australie] ; Britt Klein [Australie] ; Monica Gilbert [Australie] ; David W. Austin ; Michael Berk [Australie]

Source :

Journal of affective disorders [ 1573-2517 ] ; 2015.

RBID : pubmed:25282145

Descripteurs français

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Bipolar Disorder (psychology), Bipolar Disorder (therapy), Cognitive Behavioral Therapy (methods), Female (MeSH), Follow-Up Studies (MeSH), Health Behavior (MeSH), Humans (MeSH), Internet (MeSH), Male (MeSH), Medication Adherence (psychology), Medication Adherence (statistics & numerical data), Middle Aged (MeSH), Patient Education as Topic (methods), Program Evaluation (methods), Program Evaluation (statistics & numerical data), Quality of Life (psychology), Recurrence (MeSH), Self Care (methods), Self Care (psychology), Self Care (statistics & numerical data), Social Support (MeSH), Therapy, Computer-Assisted (methods), Treatment Outcome (MeSH), Young Adult (MeSH).
MESH :
- methods : Cognitive Behavioral Therapy, Patient Education as Topic, Program Evaluation, Self Care, Therapy, Computer-Assisted.
- psychology : Bipolar Disorder, Medication Adherence, Quality of Life, Self Care.
- statistics & numerical data : Medication Adherence, Program Evaluation, Self Care.
- therapy : Bipolar Disorder.
- Adolescent, Adult, Aged, Female, Follow-Up Studies, Health Behavior, Humans, Internet, Male, Middle Aged, Recurrence, Social Support, Treatment Outcome, Young Adult.

Abstract

BACKGROUND

Adjunctive psychosocial interventions are efficacious in bipolar disorder, but their incorporation into routine management plans are often confounded by cost and access constraints. We report here a comparative evaluation of two online programs hosted on a single website (www.moodswings.net.au). A basic version, called MoodSwings (MS), contains psychoeducation material and asynchronous discussion boards; and a more interactive program, MoodSwings Plus (MS-Plus), combined the basic psychoeducation material and discussion boards with elements of Cognitive Behavioral Therapy. These programs were evaluated in a head-to-head study design.

METHOD

Participants with Bipolar I or II disorder (n=156) were randomized to receive either MoodSwings or MoodSwings-Plus. Outcomes included mood symptoms, the occurrence of relapse, functionality, Locus of Control, social support, quality of life and medication adherence.

RESULTS

Participants in both groups showed baseline to endpoint reductions in mood symptoms and improvements in functionality, quality of life and medication adherence. The MoodSwings-Plus group showed a greater number of within-group changes on symptoms and functioning in depression and mania, quality of life and social support, across both poles of the illness. MoodSwings-Plus was superior to MoodSwings in improvement on symptoms of mania scores at 12 months (p=0.02) but not on the incidence of recurrence.

LIMITATIONS

The study did not have an attention control group and therefore could not demonstrate efficacy of the two active arms. There was notable (81%) attrition by 12 months from baseline.

CONCLUSION

This study suggests that both CBT and psychoeducation delivered online may have utility in the management of bipolar disorder. They are feasible, readily accepted, and associated with improvement.

DOI: 10.1016/j.jad.2014.08.008
PubMed: 25282145

Affiliations:

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<author><name sortKey="Lauder, Sue" sort="Lauder, Sue" uniqKey="Lauder S" first="Sue" last="Lauder">Sue Lauder</name>
<affiliation wicri:level="4"><nlm:affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; DVC-Research and Innovation Portfolio & School of Health Sciences, and the Collaborative Research Network Federation University, Ballarat, Victoria, Australia. Electronic address: suela@barwonhealth.org.au.</nlm:affiliation>
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<wicri:regionArea>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; IMPACT Strategic Research Center, School of Medicine, Deakin University, Barwon Health, P.O. Box 291, Geelong 3220</wicri:regionArea>
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<region type="état">Victoria (État)</region>
</placeName>
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<author><name sortKey="Berk, Lesley" sort="Berk, Lesley" uniqKey="Berk L" first="Lesley" last="Berk">Lesley Berk</name>
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<country xml:lang="fr">Australie</country>
<wicri:regionArea>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; Orygen Youth Health Research Center, 35 Poplar Road, Parkville 3052</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
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<author><name sortKey="Chamberlain, James" sort="Chamberlain, James" uniqKey="Chamberlain J" first="James" last="Chamberlain">James Chamberlain</name>
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<country xml:lang="fr">Australie</country>
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<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
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<author><name sortKey="Klein, Britt" sort="Klein, Britt" uniqKey="Klein B" first="Britt" last="Klein">Britt Klein</name>
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<wicri:regionArea>DVC-Research and Innovation Portfolio & School of Health Sciences, and the Collaborative Research Network Federation University, Ballarat, Victoria, Australia; National Institute for Mental Health Research, The Australian National University, Building 63, Canberra 2000, Australia; National eTherapy Center, Swinburne University of Technology, Hawthorn, Victoria</wicri:regionArea>
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<author><name sortKey="Gilbert, Monica" sort="Gilbert, Monica" uniqKey="Gilbert M" first="Monica" last="Gilbert">Monica Gilbert</name>
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<country xml:lang="fr">Australie</country>
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<placeName><settlement type="city">Melbourne</settlement>
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<author><name sortKey="Austin, David W" sort="Austin, David W" uniqKey="Austin D" first="David W" last="Austin">David W. Austin</name>
<affiliation><nlm:affiliation>Deakin University, School of Psychology, Faculty of Health, Burwood Campus, 221 Burwood Highway, Burwood 3125, Victoria Australia.</nlm:affiliation>
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<country xml:lang="fr">Australie</country>
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<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Bipolar Disorder (psychology)</term>
<term>Bipolar Disorder (therapy)</term>
<term>Cognitive Behavioral Therapy (methods)</term>
<term>Female (MeSH)</term>
<term>Follow-Up Studies (MeSH)</term>
<term>Health Behavior (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Internet (MeSH)</term>
<term>Male (MeSH)</term>
<term>Medication Adherence (psychology)</term>
<term>Medication Adherence (statistics & numerical data)</term>
<term>Middle Aged (MeSH)</term>
<term>Patient Education as Topic (methods)</term>
<term>Program Evaluation (methods)</term>
<term>Program Evaluation (statistics & numerical data)</term>
<term>Quality of Life (psychology)</term>
<term>Recurrence (MeSH)</term>
<term>Self Care (methods)</term>
<term>Self Care (psychology)</term>
<term>Self Care (statistics & numerical data)</term>
<term>Social Support (MeSH)</term>
<term>Therapy, Computer-Assisted (methods)</term>
<term>Treatment Outcome (MeSH)</term>
<term>Young Adult (MeSH)</term>
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<term>Adhésion au traitement médicamenteux (statistiques et données numériques)</term>
<term>Adolescent (MeSH)</term>
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Autosoins (méthodes)</term>
<term>Autosoins (psychologie)</term>
<term>Autosoins (statistiques et données numériques)</term>
<term>Comportement en matière de santé (MeSH)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Internet (MeSH)</term>
<term>Jeune adulte (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Qualité de vie (psychologie)</term>
<term>Récidive (MeSH)</term>
<term>Résultat thérapeutique (MeSH)</term>
<term>Soutien social (MeSH)</term>
<term>Sujet âgé (MeSH)</term>
<term>Thérapie assistée par ordinateur (méthodes)</term>
<term>Thérapie cognitive (méthodes)</term>
<term>Trouble bipolaire (psychologie)</term>
<term>Trouble bipolaire (thérapie)</term>
<term>Éducation du patient comme sujet (méthodes)</term>
<term>Études de suivi (MeSH)</term>
<term>Évaluation de programme (méthodes)</term>
<term>Évaluation de programme (statistiques et données numériques)</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Cognitive Behavioral Therapy</term>
<term>Patient Education as Topic</term>
<term>Program Evaluation</term>
<term>Self Care</term>
<term>Therapy, Computer-Assisted</term>
</keywords>
<keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Autosoins</term>
<term>Thérapie assistée par ordinateur</term>
<term>Thérapie cognitive</term>
<term>Éducation du patient comme sujet</term>
<term>Évaluation de programme</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Adhésion au traitement médicamenteux</term>
<term>Autosoins</term>
<term>Qualité de vie</term>
<term>Trouble bipolaire</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Bipolar Disorder</term>
<term>Medication Adherence</term>
<term>Quality of Life</term>
<term>Self Care</term>
</keywords>
<keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Medication Adherence</term>
<term>Program Evaluation</term>
<term>Self Care</term>
</keywords>
<keywords scheme="MESH" qualifier="statistiques et données numériques" xml:lang="fr"><term>Adhésion au traitement médicamenteux</term>
<term>Autosoins</term>
<term>Évaluation de programme</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Bipolar Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Trouble bipolaire</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Follow-Up Studies</term>
<term>Health Behavior</term>
<term>Humans</term>
<term>Internet</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Recurrence</term>
<term>Social Support</term>
<term>Treatment Outcome</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Comportement en matière de santé</term>
<term>Femelle</term>
<term>Humains</term>
<term>Internet</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Récidive</term>
<term>Résultat thérapeutique</term>
<term>Soutien social</term>
<term>Sujet âgé</term>
<term>Études de suivi</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Adjunctive psychosocial interventions are efficacious in bipolar disorder, but their incorporation into routine management plans are often confounded by cost and access constraints. We report here a comparative evaluation of two online programs hosted on a single website (www.moodswings.net.au). A basic version, called MoodSwings (MS), contains psychoeducation material and asynchronous discussion boards; and a more interactive program, MoodSwings Plus (MS-Plus), combined the basic psychoeducation material and discussion boards with elements of Cognitive Behavioral Therapy. These programs were evaluated in a head-to-head study design.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHOD</b>
</p>
<p>Participants with Bipolar I or II disorder (n=156) were randomized to receive either MoodSwings or MoodSwings-Plus. Outcomes included mood symptoms, the occurrence of relapse, functionality, Locus of Control, social support, quality of life and medication adherence.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Participants in both groups showed baseline to endpoint reductions in mood symptoms and improvements in functionality, quality of life and medication adherence. The MoodSwings-Plus group showed a greater number of within-group changes on symptoms and functioning in depression and mania, quality of life and social support, across both poles of the illness. MoodSwings-Plus was superior to MoodSwings in improvement on symptoms of mania scores at 12 months (p=0.02) but not on the incidence of recurrence.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>LIMITATIONS</b>
</p>
<p>The study did not have an attention control group and therefore could not demonstrate efficacy of the two active arms. There was notable (81%) attrition by 12 months from baseline.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>This study suggests that both CBT and psychoeducation delivered online may have utility in the management of bipolar disorder. They are feasible, readily accepted, and associated with improvement.</p>
</div>
</front>
</TEI>
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<DateCompleted><Year>2015</Year>
<Month>05</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>12</Month>
<Day>02</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1573-2517</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>171</Volume>
<PubDate><Year>2015</Year>
<Month>Jan</Month>
<Day>15</Day>
</PubDate>
</JournalIssue>
<Title>Journal of affective disorders</Title>
<ISOAbbreviation>J Affect Disord</ISOAbbreviation>
</Journal>
<ArticleTitle>A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder.</ArticleTitle>
<Pagination><MedlinePgn>13-21</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jad.2014.08.008</ELocationID>
<ELocationID EIdType="pii" ValidYN="Y">S0165-0327(14)00484-4</ELocationID>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Adjunctive psychosocial interventions are efficacious in bipolar disorder, but their incorporation into routine management plans are often confounded by cost and access constraints. We report here a comparative evaluation of two online programs hosted on a single website (www.moodswings.net.au). A basic version, called MoodSwings (MS), contains psychoeducation material and asynchronous discussion boards; and a more interactive program, MoodSwings Plus (MS-Plus), combined the basic psychoeducation material and discussion boards with elements of Cognitive Behavioral Therapy. These programs were evaluated in a head-to-head study design.</AbstractText>
<AbstractText Label="METHOD" NlmCategory="METHODS">Participants with Bipolar I or II disorder (n=156) were randomized to receive either MoodSwings or MoodSwings-Plus. Outcomes included mood symptoms, the occurrence of relapse, functionality, Locus of Control, social support, quality of life and medication adherence.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Participants in both groups showed baseline to endpoint reductions in mood symptoms and improvements in functionality, quality of life and medication adherence. The MoodSwings-Plus group showed a greater number of within-group changes on symptoms and functioning in depression and mania, quality of life and social support, across both poles of the illness. MoodSwings-Plus was superior to MoodSwings in improvement on symptoms of mania scores at 12 months (p=0.02) but not on the incidence of recurrence.</AbstractText>
<AbstractText Label="LIMITATIONS" NlmCategory="CONCLUSIONS">The study did not have an attention control group and therefore could not demonstrate efficacy of the two active arms. There was notable (81%) attrition by 12 months from baseline.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">This study suggests that both CBT and psychoeducation delivered online may have utility in the management of bipolar disorder. They are feasible, readily accepted, and associated with improvement.</AbstractText>
<CopyrightInformation>Copyright © 2014 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lauder</LastName>
<ForeName>Sue</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; DVC-Research and Innovation Portfolio & School of Health Sciences, and the Collaborative Research Network Federation University, Ballarat, Victoria, Australia. Electronic address: suela@barwonhealth.org.au.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chester</LastName>
<ForeName>Andrea</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>RMIT University, Building 6, Level 5 Bowen Street, Melbourne 3000, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Castle</LastName>
<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, St Vincent׳s Hospital, P.O. Box, 2900, Fitzroy 3065, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dodd</LastName>
<ForeName>Seetal</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; IMPACT Strategic Research Center, School of Medicine, Deakin University, Barwon Health, P.O. Box 291, Geelong 3220, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gliddon</LastName>
<ForeName>Emma</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; IMPACT Strategic Research Center, School of Medicine, Deakin University, Barwon Health, P.O. Box 291, Geelong 3220, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berk</LastName>
<ForeName>Lesley</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; Orygen Youth Health Research Center, 35 Poplar Road, Parkville 3052, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chamberlain</LastName>
<ForeName>James</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Healthmaps Pty Ltd, PO Box 2501, Fitzroy, 3065 Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Klein</LastName>
<ForeName>Britt</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>DVC-Research and Innovation Portfolio & School of Health Sciences, and the Collaborative Research Network Federation University, Ballarat, Victoria, Australia; National Institute for Mental Health Research, The Australian National University, Building 63, Canberra 2000, Australia; National eTherapy Center, Swinburne University of Technology, Hawthorn, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gilbert</LastName>
<ForeName>Monica</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Healthmaps Pty Ltd, PO Box 2501, Fitzroy, 3065 Melbourne, Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Austin</LastName>
<ForeName>David W</ForeName>
<Initials>DW</Initials>
<AffiliationInfo><Affiliation>Deakin University, School of Psychology, Faculty of Health, Burwood Campus, 221 Burwood Highway, Burwood 3125, Victoria Australia.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Berk</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>The University of Melbourne, Department of Psychiatry, Royal Melbourne Hospital, Level 1 North, Main Block, Victoria 3050, Australia; IMPACT Strategic Research Center, School of Medicine, Deakin University, Barwon Health, P.O. Box 291, Geelong 3220, Australia; Orygen Youth Health Research Center, 35 Poplar Road, Parkville 3052, Australia; Florey Institute for Neuroscience and Mental Health, The University of Melbourne, Kenneth Myer Building, 30 Royal Parade, 3052 Parkville, Victoria, Australia.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<DataBankList CompleteYN="Y"><DataBank><DataBankName>ANZCTR</DataBankName>
<AccessionNumberList><AccessionNumber>12607000118404</AccessionNumber>
</AccessionNumberList>
</DataBank>
</DataBankList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016449">Randomized Controlled Trial</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2014</Year>
<Month>09</Month>
<Day>22</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>J Affect Disord</MedlineTA>
<NlmUniqueID>7906073</NlmUniqueID>
<ISSNLinking>0165-0327</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001714" MajorTopicYN="N">Bipolar Disorder</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015928" MajorTopicYN="N">Cognitive Behavioral Therapy</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015438" MajorTopicYN="N">Health Behavior</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D020407" MajorTopicYN="Y">Internet</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055118" MajorTopicYN="N">Medication Adherence</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010353" MajorTopicYN="N">Patient Education as Topic</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015397" MajorTopicYN="N">Program Evaluation</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012008" MajorTopicYN="N">Recurrence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012648" MajorTopicYN="N">Self Care</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName>
<QualifierName UI="Q000706" MajorTopicYN="N">statistics & numerical data</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012944" MajorTopicYN="N">Social Support</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D013813" MajorTopicYN="N">Therapy, Computer-Assisted</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Bipolar disorder</Keyword>
<Keyword MajorTopicYN="N">CBT</Keyword>
<Keyword MajorTopicYN="N">Internet</Keyword>
<Keyword MajorTopicYN="N">Online</Keyword>
<Keyword MajorTopicYN="N">Psychoeducation</Keyword>
<Keyword MajorTopicYN="N">Psychological</Keyword>
</KeywordList>
</MedlineCitation>
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<Month>02</Month>
<Day>26</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2014</Year>
<Month>07</Month>
<Day>25</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2014</Year>
<Month>08</Month>
<Day>06</Day>
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<PubMedPubDate PubStatus="entrez"><Year>2014</Year>
<Month>10</Month>
<Day>6</Day>
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<tree><noCountry><name sortKey="Austin, David W" sort="Austin, David W" uniqKey="Austin D" first="David W" last="Austin">David W. Austin</name>
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<name sortKey="Berk, Lesley" sort="Berk, Lesley" uniqKey="Berk L" first="Lesley" last="Berk">Lesley Berk</name>
<name sortKey="Berk, Michael" sort="Berk, Michael" uniqKey="Berk M" first="Michael" last="Berk">Michael Berk</name>
<name sortKey="Castle, David" sort="Castle, David" uniqKey="Castle D" first="David" last="Castle">David Castle</name>
<name sortKey="Chamberlain, James" sort="Chamberlain, James" uniqKey="Chamberlain J" first="James" last="Chamberlain">James Chamberlain</name>
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A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder.

A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder.

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