Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes.
Identifieur interne : 001033 ( Main/Exploration ); précédent : 001032; suivant : 001034Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes.
Auteurs : Shiqin Peng [République populaire de Chine] ; Ping Wei [République populaire de Chine] ; Qun Lu [République populaire de Chine] ; Rui Liu [République populaire de Chine] ; Yue Ding [République populaire de Chine] ; Jiuliang Zhang [République populaire de Chine]Source :
- Journal of immunology research [ 2314-7156 ] ; 2018.
Descripteurs français
- KwdFr :
- Animaux (MeSH), Complications du diabète (traitement médicamenteux), Cyclooxygenase 2 (métabolisme), Cytokines (métabolisme), Diabète de type 2 (traitement médicamenteux), Diabète expérimental (MeSH), Dyslipidémies (traitement médicamenteux), Extraits de plantes (usage thérapeutique), Foie (anatomopathologie), Foie (métabolisme), Humains (MeSH), Hyperglycémie (traitement médicamenteux), Inflammation (traitement médicamenteux), Insulinorésistance (MeSH), Lignées consanguines de souris (MeSH), Modèles animaux de maladie humaine (MeSH), Mâle (MeSH), Populus (immunologie), Propolis (immunologie), Souris (MeSH), Stress oxydatif (effets des médicaments et des substances chimiques).
- MESH :
- anatomopathologie : Foie.
- effets des médicaments et des substances chimiques : Stress oxydatif.
- immunologie : Populus, Propolis.
- métabolisme : Cyclooxygenase 2, Cytokines, Foie.
- traitement médicamenteux : Complications du diabète, Diabète de type 2, Dyslipidémies, Hyperglycémie, Inflammation.
- usage thérapeutique : Extraits de plantes.
- Animaux, Diabète expérimental, Humains, Insulinorésistance, Lignées consanguines de souris, Modèles animaux de maladie humaine, Mâle, Souris.
English descriptors
- KwdEn :
- Animals (MeSH), Cyclooxygenase 2 (metabolism), Cytokines (metabolism), Diabetes Complications (drug therapy), Diabetes Mellitus, Experimental (MeSH), Diabetes Mellitus, Type 2 (drug therapy), Disease Models, Animal (MeSH), Dyslipidemias (drug therapy), Humans (MeSH), Hyperglycemia (drug therapy), Inflammation (drug therapy), Insulin Resistance (MeSH), Liver (metabolism), Liver (pathology), Male (MeSH), Mice (MeSH), Mice, Inbred Strains (MeSH), Oxidative Stress (drug effects), Plant Extracts (therapeutic use), Populus (immunology), Propolis (immunology).
- MESH :
- chemical , immunology : Propolis.
- chemical , metabolism : Cyclooxygenase 2, Cytokines.
- drug effects : Oxidative Stress.
- drug therapy : Diabetes Complications, Diabetes Mellitus, Type 2, Dyslipidemias, Hyperglycemia, Inflammation.
- immunology : Populus.
- metabolism : Liver.
- pathology : Liver.
- chemical , therapeutic use : Plant Extracts.
- Animals, Diabetes Mellitus, Experimental, Disease Models, Animal, Humans, Insulin Resistance, Male, Mice, Mice, Inbred Strains.
Abstract
The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate the effect of poplar buds on type-2 diabetes, crude extract and 50% fraction of poplar buds were used to feed streptozotocin-induced type-2 diabetic mice. The results showed that 50% fraction could increase insulin sensitivity and reduce insulin resistance, as well as decrease the levels of fasting blood glucose, glycated hemoglobin, and glycosylated serum proteins in diabetic mice. Compared with the model control group, the 50% fraction-treated group showed significant decreases of malondialdehyde (MDA) and increases of superoxide dismutase (SOD) in serum and liver homogenate. Moreover, 50% fraction could significantly decrease total cholesterol (TC), alleviate abnormal lipid metabolism, and enhance antioxidant capacity in the serum. For inflammatory factors, feeding of 50% fraction could also reduce the levels of interleukin 6 (IL-6), tumor necrosis factor α (TNF-α), monocyte chemotactic protein 1 (MCP-1), and cyclooxygenase-2 (COX-2) in liver homogenate. Taken together, our results suggest that crude extract and 50% fraction of poplar buds, particularly the latter, can decrease blood glucose levels and insulin resistance, and 50% fraction can significantly relieve dyslipidemia, oxidative stress, and inflammation caused by type-2 diabetes.
DOI: 10.1155/2018/7245956
PubMed: 30320140
PubMed Central: PMC6167568
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term>
<term>Cyclooxygenase 2 (metabolism)</term>
<term>Cytokines (metabolism)</term>
<term>Diabetes Complications (drug therapy)</term>
<term>Diabetes Mellitus, Experimental (MeSH)</term>
<term>Diabetes Mellitus, Type 2 (drug therapy)</term>
<term>Disease Models, Animal (MeSH)</term>
<term>Dyslipidemias (drug therapy)</term>
<term>Humans (MeSH)</term>
<term>Hyperglycemia (drug therapy)</term>
<term>Inflammation (drug therapy)</term>
<term>Insulin Resistance (MeSH)</term>
<term>Liver (metabolism)</term>
<term>Liver (pathology)</term>
<term>Male (MeSH)</term>
<term>Mice (MeSH)</term>
<term>Mice, Inbred Strains (MeSH)</term>
<term>Oxidative Stress (drug effects)</term>
<term>Plant Extracts (therapeutic use)</term>
<term>Populus (immunology)</term>
<term>Propolis (immunology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term>
<term>Complications du diabète (traitement médicamenteux)</term>
<term>Cyclooxygenase 2 (métabolisme)</term>
<term>Cytokines (métabolisme)</term>
<term>Diabète de type 2 (traitement médicamenteux)</term>
<term>Diabète expérimental (MeSH)</term>
<term>Dyslipidémies (traitement médicamenteux)</term>
<term>Extraits de plantes (usage thérapeutique)</term>
<term>Foie (anatomopathologie)</term>
<term>Foie (métabolisme)</term>
<term>Humains (MeSH)</term>
<term>Hyperglycémie (traitement médicamenteux)</term>
<term>Inflammation (traitement médicamenteux)</term>
<term>Insulinorésistance (MeSH)</term>
<term>Lignées consanguines de souris (MeSH)</term>
<term>Modèles animaux de maladie humaine (MeSH)</term>
<term>Mâle (MeSH)</term>
<term>Populus (immunologie)</term>
<term>Propolis (immunologie)</term>
<term>Souris (MeSH)</term>
<term>Stress oxydatif (effets des médicaments et des substances chimiques)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Propolis</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cyclooxygenase 2</term>
<term>Cytokines</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Foie</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Oxidative Stress</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Diabetes Complications</term>
<term>Diabetes Mellitus, Type 2</term>
<term>Dyslipidemias</term>
<term>Hyperglycemia</term>
<term>Inflammation</term>
</keywords>
<keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Stress oxydatif</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Populus</term>
<term>Propolis</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Populus</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Liver</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Cyclooxygenase 2</term>
<term>Cytokines</term>
<term>Foie</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Liver</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Complications du diabète</term>
<term>Diabète de type 2</term>
<term>Dyslipidémies</term>
<term>Hyperglycémie</term>
<term>Inflammation</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Extraits de plantes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Diabetes Mellitus, Experimental</term>
<term>Disease Models, Animal</term>
<term>Humans</term>
<term>Insulin Resistance</term>
<term>Male</term>
<term>Mice</term>
<term>Mice, Inbred Strains</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Diabète expérimental</term>
<term>Humains</term>
<term>Insulinorésistance</term>
<term>Lignées consanguines de souris</term>
<term>Modèles animaux de maladie humaine</term>
<term>Mâle</term>
<term>Souris</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate the effect of poplar buds on type-2 diabetes, crude extract and 50% fraction of poplar buds were used to feed streptozotocin-induced type-2 diabetic mice. The results showed that 50% fraction could increase insulin sensitivity and reduce insulin resistance, as well as decrease the levels of fasting blood glucose, glycated hemoglobin, and glycosylated serum proteins in diabetic mice. Compared with the model control group, the 50% fraction-treated group showed significant decreases of malondialdehyde (MDA) and increases of superoxide dismutase (SOD) in serum and liver homogenate. Moreover, 50% fraction could significantly decrease total cholesterol (TC), alleviate abnormal lipid metabolism, and enhance antioxidant capacity in the serum. For inflammatory factors, feeding of 50% fraction could also reduce the levels of interleukin 6 (IL-6), tumor necrosis factor <i>α</i>
(TNF-<i>α</i>
), monocyte chemotactic protein 1 (MCP-1), and cyclooxygenase-2 (COX-2) in liver homogenate. Taken together, our results suggest that crude extract and 50% fraction of poplar buds, particularly the latter, can decrease blood glucose levels and insulin resistance, and 50% fraction can significantly relieve dyslipidemia, oxidative stress, and inflammation caused by type-2 diabetes.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">30320140</PMID>
<DateCompleted><Year>2018</Year>
<Month>12</Month>
<Day>27</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>12</Month>
<Day>27</Day>
</DateRevised>
<Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">2314-7156</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>2018</Volume>
<PubDate><Year>2018</Year>
</PubDate>
</JournalIssue>
<Title>Journal of immunology research</Title>
<ISOAbbreviation>J Immunol Res</ISOAbbreviation>
</Journal>
<ArticleTitle>Beneficial Effects of Poplar Buds on Hyperglycemia, Dyslipidemia, Oxidative Stress, and Inflammation in Streptozotocin-Induced Type-2 Diabetes.</ArticleTitle>
<Pagination><MedlinePgn>7245956</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1155/2018/7245956</ELocationID>
<Abstract><AbstractText>The effects of propolis on blood glucose regulation and the alleviation of various complications caused by diabetes have been widely studied. The main source of propolis in the northern temperate zone is poplar buds. However, there is limited research on the antidiabetic activity of poplar buds. In order to evaluate the effect of poplar buds on type-2 diabetes, crude extract and 50% fraction of poplar buds were used to feed streptozotocin-induced type-2 diabetic mice. The results showed that 50% fraction could increase insulin sensitivity and reduce insulin resistance, as well as decrease the levels of fasting blood glucose, glycated hemoglobin, and glycosylated serum proteins in diabetic mice. Compared with the model control group, the 50% fraction-treated group showed significant decreases of malondialdehyde (MDA) and increases of superoxide dismutase (SOD) in serum and liver homogenate. Moreover, 50% fraction could significantly decrease total cholesterol (TC), alleviate abnormal lipid metabolism, and enhance antioxidant capacity in the serum. For inflammatory factors, feeding of 50% fraction could also reduce the levels of interleukin 6 (IL-6), tumor necrosis factor <i>α</i>
(TNF-<i>α</i>
), monocyte chemotactic protein 1 (MCP-1), and cyclooxygenase-2 (COX-2) in liver homogenate. Taken together, our results suggest that crude extract and 50% fraction of poplar buds, particularly the latter, can decrease blood glucose levels and insulin resistance, and 50% fraction can significantly relieve dyslipidemia, oxidative stress, and inflammation caused by type-2 diabetes.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Peng</LastName>
<ForeName>Shiqin</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wei</LastName>
<ForeName>Ping</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lu</LastName>
<ForeName>Qun</ForeName>
<Initials>Q</Initials>
<Identifier Source="ORCID">0000-0002-6211-6565</Identifier>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wuhan Engineering Research Center of Bee Products on Quality and Safety Control, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Rui</ForeName>
<Initials>R</Initials>
<Identifier Source="ORCID">0000-0001-5820-0177</Identifier>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wuhan Engineering Research Center of Bee Products on Quality and Safety Control, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ding</LastName>
<ForeName>Yue</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Jiuliang</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Wuhan Engineering Research Center of Bee Products on Quality and Safety Control, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Key Laboratory of Environment Correlative Dietology (Huazhong Agricultural University), Ministry of Education, Wuhan 430070, China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2018</Year>
<Month>09</Month>
<Day>18</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Egypt</Country>
<MedlineTA>J Immunol Res</MedlineTA>
<NlmUniqueID>101627166</NlmUniqueID>
<ISSNLinking>2314-7156</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016207">Cytokines</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010936">Plant Extracts</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9009-62-5</RegistryNumber>
<NameOfSubstance UI="D011429">Propolis</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.14.99.1</RegistryNumber>
<NameOfSubstance UI="D051546">Cyclooxygenase 2</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051546" MajorTopicYN="N">Cyclooxygenase 2</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016207" MajorTopicYN="N">Cytokines</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D048909" MajorTopicYN="N">Diabetes Complications</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003921" MajorTopicYN="N">Diabetes Mellitus, Experimental</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003924" MajorTopicYN="N">Diabetes Mellitus, Type 2</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004195" MajorTopicYN="N">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D050171" MajorTopicYN="N">Dyslipidemias</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006943" MajorTopicYN="N">Hyperglycemia</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007249" MajorTopicYN="N">Inflammation</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007333" MajorTopicYN="N">Insulin Resistance</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008815" MajorTopicYN="N">Mice, Inbred Strains</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018384" MajorTopicYN="N">Oxidative Stress</DescriptorName>
<QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010936" MajorTopicYN="N">Plant Extracts</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D032107" MajorTopicYN="N">Populus</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011429" MajorTopicYN="N">Propolis</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2018</Year>
<Month>04</Month>
<Day>11</Day>
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<PubMedPubDate PubStatus="revised"><Year>2018</Year>
<Month>07</Month>
<Day>15</Day>
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<PubMedPubDate PubStatus="accepted"><Year>2018</Year>
<Month>07</Month>
<Day>26</Day>
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<Month>10</Month>
<Day>16</Day>
<Hour>6</Hour>
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<Month>12</Month>
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<ReferenceList><Reference><Citation>Endocrinology. 1997 Jan;138(1):62-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8977386</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Can J Diabetes. 2015 Feb;39(1):44-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25065473</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem J. 1999 Nov 15;344 Pt 1:109-16</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10548540</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Complement Altern Med. 2013 Nov 27;13:337</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24279635</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Physiol Rev. 2013 Jan;93(1):137-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23303908</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Nutr Biochem. 2013 Nov;24(11):1777-89</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24029069</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Diabetes Complications. 2016 May-Jun;30(4):738-45</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26781070</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Hum Exp Toxicol. 2011 Sep;30(9):1246-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20956460</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 1992 Oct 17;340(8825):925-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">1357346</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biochem Mol Toxicol. 2003;17(1):24-38</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12616644</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biomed Res Int. 2014;2014:160695</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24822178</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mediators Inflamm. 2010;2010:194896</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20652055</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Med (Zagreb). 2012;22(1):49-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22384519</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Evid Based Complement Alternat Med. 2017;2017:5439645</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28298934</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Clin Invest. 2005 May;115(5):1111-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15864338</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Ethnopharmacol. 2014 Aug 8;155(1):300-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24882729</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Intercult Ethnopharmacol. 2016 May 04;5(3):233-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27366348</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Atherosclerosis. 2015 Apr;239(2):483-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25706066</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nat Clin Pract Endocrinol Metab. 2009 Mar;5(3):150-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19229235</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Evid Based Complement Alternat Med. 2017;2017:5163575</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28127379</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Fitoterapia. 2002 Nov;73 Suppl 1:S7-20</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12495705</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Blood. 1994 Jan 1;83(1):113-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8274730</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Agric Food Chem. 2011 May 11;59(9):4527-36</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21425781</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pak J Pharm Sci. 2009 Apr;22(2):168-74</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19339227</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Food Chem Toxicol. 1998 Apr;36(4):347-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9651052</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>BMC Complement Altern Med. 2012 Aug 06;12:117</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22866906</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Protoc Mouse Biol. 2015 Mar 02;5(1):65-84</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25727201</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Environ Res Public Health. 2016 May 13;13(5):</Citation>
<ArticleIdList><ArticleId IdType="pubmed">27187435</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2011 May;1813(5):878-88</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21296109</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochem Biophys Res Commun. 2013 Mar 22;432(4):650-3</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23416075</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Lancet. 2010 Apr 24;375(9724):1434; author reply 1434-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20417853</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Food Funct. 2018 Jan 24;9(1):450-462</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29227493</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Integr Med. 2017 Mar;15(2):124-134</Citation>
<ArticleIdList><ArticleId IdType="pubmed">28285617</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Biochim Biophys Acta. 2013 Nov;1831(11):1609-17</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23896361</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1996 Apr 26;271(17):9982-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8626637</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Food Funct. 2018 Mar 1;9(3):1779-1789</Citation>
<ArticleIdList><ArticleId IdType="pubmed">29508881</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
<region><li>Hubei</li>
</region>
<settlement><li>Wuhan</li>
</settlement>
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<tree><country name="République populaire de Chine"><region name="Hubei"><name sortKey="Peng, Shiqin" sort="Peng, Shiqin" uniqKey="Peng S" first="Shiqin" last="Peng">Shiqin Peng</name>
</region>
<name sortKey="Ding, Yue" sort="Ding, Yue" uniqKey="Ding Y" first="Yue" last="Ding">Yue Ding</name>
<name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name>
<name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name>
<name sortKey="Liu, Rui" sort="Liu, Rui" uniqKey="Liu R" first="Rui" last="Liu">Rui Liu</name>
<name sortKey="Lu, Qun" sort="Lu, Qun" uniqKey="Lu Q" first="Qun" last="Lu">Qun Lu</name>
<name sortKey="Lu, Qun" sort="Lu, Qun" uniqKey="Lu Q" first="Qun" last="Lu">Qun Lu</name>
<name sortKey="Lu, Qun" sort="Lu, Qun" uniqKey="Lu Q" first="Qun" last="Lu">Qun Lu</name>
<name sortKey="Wei, Ping" sort="Wei, Ping" uniqKey="Wei P" first="Ping" last="Wei">Ping Wei</name>
<name sortKey="Zhang, Jiuliang" sort="Zhang, Jiuliang" uniqKey="Zhang J" first="Jiuliang" last="Zhang">Jiuliang Zhang</name>
<name sortKey="Zhang, Jiuliang" sort="Zhang, Jiuliang" uniqKey="Zhang J" first="Jiuliang" last="Zhang">Jiuliang Zhang</name>
<name sortKey="Zhang, Jiuliang" sort="Zhang, Jiuliang" uniqKey="Zhang J" first="Jiuliang" last="Zhang">Jiuliang Zhang</name>
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