CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.
Identifieur interne : 000525 ( Main/Exploration ); précédent : 000524; suivant : 000526CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.
Auteurs : Yangfan Li [République populaire de Chine] ; Puhuizhong He [République populaire de Chine] ; Chengming Tian [République populaire de Chine] ; Yonglin Wang [République populaire de Chine]Source :
- Fungal genetics and biology : FG & B [ 1096-0937 ] ; 2020.
Abstract
The HOG (high-osmolarity glycerol) pathway is critical for the appropriate adaptation to adverse conditions. Here, we demonstrated that the deletion of CgHog1 resulted in enhanced sensitivity to osmotic stress and increased resistance to fludioxonil in the poplar anthracnose fungus Colletotrichum gloeosporioides. The accumulation of chitin around hyphal tips was obviously decreased in the ΔCgHog1 strain under sorbitol, whereas it strongly was increased in the response to fludioxonil compared with the wild type. To investigate the underlying mechanism of CgHog1-mediated adaption to osmotic stress and fludioxonil, transcriptomic profiles were performed in both the ΔCgHog1 strain and the wild type under the treatment of sorbitol and fludioxonil, respectively. Under sorbitol, genes associated with glycolysis, lipid metabolism, and accumulation of soluble sugars and amino acids were differentially expressed; under fludioxonil, vesicle trafficking-related genes were highly downregulated in the ΔCgHog1 strain, which was consistent with abnormal vacuoles distribution and morphology of hyphae, indicating that the growth defect caused by fludioxonil may be associated with disruption of endocytosis. Taken together, we elucidated the adaptation mechanisms of how CgHog1 regulates appropriate response to sorbitol and fludioxonil via different metabolism pathways. These findings extend our insights into the HOG pathway in fungi.
DOI: 10.1016/j.fgb.2019.103289
PubMed: 31704368
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.</title><author><name sortKey="Li, Yangfan" sort="Li, Yangfan" uniqKey="Li Y" first="Yangfan" last="Li">Yangfan Li</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="He, Puhuizhong" sort="He, Puhuizhong" uniqKey="He P" first="Puhuizhong" last="He">Puhuizhong He</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Tian, Chengming" sort="Tian, Chengming" uniqKey="Tian C" first="Chengming" last="Tian">Chengming Tian</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Yonglin" sort="Wang, Yonglin" uniqKey="Wang Y" first="Yonglin" last="Wang">Yonglin Wang</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China. Electronic address: ylwang@bjfu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:31704368</idno><idno type="pmid">31704368</idno><idno type="doi">10.1016/j.fgb.2019.103289</idno><idno type="wicri:Area/Main/Corpus">000628</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000628</idno><idno type="wicri:Area/Main/Curation">000628</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000628</idno><idno type="wicri:Area/Main/Exploration">000628</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.</title><author><name sortKey="Li, Yangfan" sort="Li, Yangfan" uniqKey="Li Y" first="Yangfan" last="Li">Yangfan Li</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="He, Puhuizhong" sort="He, Puhuizhong" uniqKey="He P" first="Puhuizhong" last="He">Puhuizhong He</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Tian, Chengming" sort="Tian, Chengming" uniqKey="Tian C" first="Chengming" last="Tian">Chengming Tian</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Wang, Yonglin" sort="Wang, Yonglin" uniqKey="Wang Y" first="Yonglin" last="Wang">Yonglin Wang</name><affiliation wicri:level="3"><nlm:affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China. Electronic address: ylwang@bjfu.edu.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author></analytic><series><title level="j">Fungal genetics and biology : FG & B</title><idno type="eISSN">1096-0937</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The HOG (high-osmolarity glycerol) pathway is critical for the appropriate adaptation to adverse conditions. Here, we demonstrated that the deletion of CgHog1 resulted in enhanced sensitivity to osmotic stress and increased resistance to fludioxonil in the poplar anthracnose fungus Colletotrichum gloeosporioides. The accumulation of chitin around hyphal tips was obviously decreased in the ΔCgHog1 strain under sorbitol, whereas it strongly was increased in the response to fludioxonil compared with the wild type. To investigate the underlying mechanism of CgHog1-mediated adaption to osmotic stress and fludioxonil, transcriptomic profiles were performed in both the ΔCgHog1 strain and the wild type under the treatment of sorbitol and fludioxonil, respectively. Under sorbitol, genes associated with glycolysis, lipid metabolism, and accumulation of soluble sugars and amino acids were differentially expressed; under fludioxonil, vesicle trafficking-related genes were highly downregulated in the ΔCgHog1 strain, which was consistent with abnormal vacuoles distribution and morphology of hyphae, indicating that the growth defect caused by fludioxonil may be associated with disruption of endocytosis. Taken together, we elucidated the adaptation mechanisms of how CgHog1 regulates appropriate response to sorbitol and fludioxonil via different metabolism pathways. These findings extend our insights into the HOG pathway in fungi.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">31704368</PMID><DateRevised><Year>2020</Year><Month>07</Month><Day>31</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1096-0937</ISSN><JournalIssue CitedMedium="Internet"><Volume>135</Volume><PubDate><Year>2020</Year><Month>02</Month></PubDate></JournalIssue><Title>Fungal genetics and biology : FG & B</Title><ISOAbbreviation>Fungal Genet Biol</ISOAbbreviation></Journal><ArticleTitle>CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.</ArticleTitle><Pagination><MedlinePgn>103289</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S1087-1845(19)30268-3</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.fgb.2019.103289</ELocationID><Abstract><AbstractText>The HOG (high-osmolarity glycerol) pathway is critical for the appropriate adaptation to adverse conditions. Here, we demonstrated that the deletion of CgHog1 resulted in enhanced sensitivity to osmotic stress and increased resistance to fludioxonil in the poplar anthracnose fungus Colletotrichum gloeosporioides. The accumulation of chitin around hyphal tips was obviously decreased in the ΔCgHog1 strain under sorbitol, whereas it strongly was increased in the response to fludioxonil compared with the wild type. To investigate the underlying mechanism of CgHog1-mediated adaption to osmotic stress and fludioxonil, transcriptomic profiles were performed in both the ΔCgHog1 strain and the wild type under the treatment of sorbitol and fludioxonil, respectively. Under sorbitol, genes associated with glycolysis, lipid metabolism, and accumulation of soluble sugars and amino acids were differentially expressed; under fludioxonil, vesicle trafficking-related genes were highly downregulated in the ΔCgHog1 strain, which was consistent with abnormal vacuoles distribution and morphology of hyphae, indicating that the growth defect caused by fludioxonil may be associated with disruption of endocytosis. Taken together, we elucidated the adaptation mechanisms of how CgHog1 regulates appropriate response to sorbitol and fludioxonil via different metabolism pathways. These findings extend our insights into the HOG pathway in fungi.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Yangfan</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>He</LastName><ForeName>Puhuizhong</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tian</LastName><ForeName>Chengming</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yonglin</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>Beijing Key Laboratory for Forest Pest Control, College of Forestry, Beijing Forestry University, Beijing, China. Electronic address: ylwang@bjfu.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>11</Month><Day>05</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Fungal Genet Biol</MedlineTA><NlmUniqueID>9607601</NlmUniqueID><ISSNLinking>1087-1845</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">Adaption</Keyword><Keyword MajorTopicYN="Y">CgHog1</Keyword><Keyword MajorTopicYN="Y">Colletotrichum gloeosporioides</Keyword><Keyword MajorTopicYN="Y">Fludioxonil</Keyword><Keyword MajorTopicYN="Y">Osmotic stress</Keyword><Keyword MajorTopicYN="Y">Transcriptome</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>08</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>10</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>10</Month><Day>30</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>11</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2019</Year><Month>11</Month><Day>11</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>11</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31704368</ArticleId><ArticleId IdType="pii">S1087-1845(19)30268-3</ArticleId><ArticleId IdType="doi">10.1016/j.fgb.2019.103289</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Yangfan" sort="Li, Yangfan" uniqKey="Li Y" first="Yangfan" last="Li">Yangfan Li</name></noRegion><name sortKey="He, Puhuizhong" sort="He, Puhuizhong" uniqKey="He P" first="Puhuizhong" last="He">Puhuizhong He</name><name sortKey="Tian, Chengming" sort="Tian, Chengming" uniqKey="Tian C" first="Chengming" last="Tian">Chengming Tian</name><name sortKey="Wang, Yonglin" sort="Wang, Yonglin" uniqKey="Wang Y" first="Yonglin" last="Wang">Yonglin Wang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PoplarV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000525 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000525 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= PoplarV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:31704368
|texte= CgHog1 controls the adaptation to both sorbitol and fludioxonil in Colletotrichum gloeosporioides.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31704368" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a PoplarV1
| This area was generated with Dilib version V0.6.37. |  |