[From willow bark to acetylsalicylic acid].
Identifieur interne : 003707 ( Main/Curation ); précédent : 003706; suivant : 003708[From willow bark to acetylsalicylic acid].
Auteurs : Svend Norn [Danemark] ; Henrik Permin ; Poul R. Kruse ; Edith KruseSource :
- Dansk medicinhistorisk arbog [ 0084-9588 ] ; 2009.
Descripteurs français
- KwdFr :
- Acide acétylsalicylique (histoire), Acide acétylsalicylique (usage thérapeutique), Anti-inflammatoires non stéroïdiens (usage thérapeutique), Douleur (traitement médicamenteux), Extraits de plantes (histoire), Extraits de plantes (usage thérapeutique), Histoire ancienne (MeSH), Histoire du 19ème siècle (MeSH), Histoire du 20ème siècle (MeSH), Histoire médiévale (MeSH), Humains (MeSH), Produits biologiques (histoire), Produits biologiques (usage thérapeutique), Rhumatisme articulaire aigu (traitement médicamenteux).
- MESH :
- histoire : Acide acétylsalicylique, Extraits de plantes, Produits biologiques.
- traitement médicamenteux : Douleur, Rhumatisme articulaire aigu.
- usage thérapeutique : Acide acétylsalicylique, Anti-inflammatoires non stéroïdiens, Extraits de plantes, Produits biologiques.
- Histoire ancienne, Histoire du 19ème siècle, Histoire du 20ème siècle, Histoire médiévale, Humains.
English descriptors
- KwdEn :
- Anti-Inflammatory Agents, Non-Steroidal (therapeutic use), Aspirin (history), Aspirin (therapeutic use), Biological Products (history), Biological Products (therapeutic use), History, 19th Century (MeSH), History, 20th Century (MeSH), History, Ancient (MeSH), History, Medieval (MeSH), Humans (MeSH), Pain (drug therapy), Plant Extracts (history), Plant Extracts (therapeutic use), Rheumatic Fever (drug therapy).
- MESH :
- chemical , history : Aspirin, Biological Products, Plant Extracts.
- chemical , therapeutic use : Anti-Inflammatory Agents, Non-Steroidal, Aspirin, Biological Products, Plant Extracts.
- drug therapy : Pain, Rheumatic Fever.
- History, 19th Century, History, 20th Century, History, Ancient, History, Medieval, Humans.
Abstract
Acetylsalicylic acid is one of the most widely used drugs in the world. Its ancestry the salicylates, including salicin and salicylic acid, are found in the bark and leaves of the willow and poplar trees. The ancient Sumerians and Egyptians, as well as Hippocrates, Celsus, Pliny the Elder, Dioscorides and Galen used these natural products as remedies for pain, fever and inflammation. In the Middle Ages these remedies were used for fever and rheumatism by Hildegard of Bingen and Henrik Harpestreng. The first "clinical trial" was reported by Edward Stone in 1763 with a successful treatment of malarial fever with the willow bark. In 1876 the antirheumatic effect of salicin was described by T. MacLagan, and that of salicylic acid by S. Stricker and L. Riess. Acetylsalicylic acid was synthesized by Charles Gerhardt in 1853 and in 1897 by Felix Hoffmann in the Bayer Company. The beneficial effect of acetylsalicylic acid (Aspirin) on pain and rheumatic fever was recognized by K. Witthauer and J. Wohlgemuth, and the mechanism of action was explained in 1971 by John Vane. Today the antithrombotic effect of acetylsalicylic acid and new aspects of ongoing research demonstrates a still living drug.
PubMed: 20509453
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pubmed:20509453Le document en format XML
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<country wicri:rule="url">Danemark</country>
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<author><name sortKey="Permin, Henrik" sort="Permin, Henrik" uniqKey="Permin H" first="Henrik" last="Permin">Henrik Permin</name>
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<author><name sortKey="Kruse, Poul R" sort="Kruse, Poul R" uniqKey="Kruse P" first="Poul R" last="Kruse">Poul R. Kruse</name>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)</term>
<term>Aspirin (history)</term>
<term>Aspirin (therapeutic use)</term>
<term>Biological Products (history)</term>
<term>Biological Products (therapeutic use)</term>
<term>History, 19th Century (MeSH)</term>
<term>History, 20th Century (MeSH)</term>
<term>History, Ancient (MeSH)</term>
<term>History, Medieval (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Pain (drug therapy)</term>
<term>Plant Extracts (history)</term>
<term>Plant Extracts (therapeutic use)</term>
<term>Rheumatic Fever (drug therapy)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Acide acétylsalicylique (histoire)</term>
<term>Acide acétylsalicylique (usage thérapeutique)</term>
<term>Anti-inflammatoires non stéroïdiens (usage thérapeutique)</term>
<term>Douleur (traitement médicamenteux)</term>
<term>Extraits de plantes (histoire)</term>
<term>Extraits de plantes (usage thérapeutique)</term>
<term>Histoire ancienne (MeSH)</term>
<term>Histoire du 19ème siècle (MeSH)</term>
<term>Histoire du 20ème siècle (MeSH)</term>
<term>Histoire médiévale (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Produits biologiques (histoire)</term>
<term>Produits biologiques (usage thérapeutique)</term>
<term>Rhumatisme articulaire aigu (traitement médicamenteux)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="history" xml:lang="en"><term>Aspirin</term>
<term>Biological Products</term>
<term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Inflammatory Agents, Non-Steroidal</term>
<term>Aspirin</term>
<term>Biological Products</term>
<term>Plant Extracts</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Pain</term>
<term>Rheumatic Fever</term>
</keywords>
<keywords scheme="MESH" qualifier="histoire" xml:lang="fr"><term>Acide acétylsalicylique</term>
<term>Extraits de plantes</term>
<term>Produits biologiques</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Douleur</term>
<term>Rhumatisme articulaire aigu</term>
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<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Acide acétylsalicylique</term>
<term>Anti-inflammatoires non stéroïdiens</term>
<term>Extraits de plantes</term>
<term>Produits biologiques</term>
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<term>History, 20th Century</term>
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<term>History, Medieval</term>
<term>Humans</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Histoire ancienne</term>
<term>Histoire du 19ème siècle</term>
<term>Histoire du 20ème siècle</term>
<term>Histoire médiévale</term>
<term>Humains</term>
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<front><div type="abstract" xml:lang="en">Acetylsalicylic acid is one of the most widely used drugs in the world. Its ancestry the salicylates, including salicin and salicylic acid, are found in the bark and leaves of the willow and poplar trees. The ancient Sumerians and Egyptians, as well as Hippocrates, Celsus, Pliny the Elder, Dioscorides and Galen used these natural products as remedies for pain, fever and inflammation. In the Middle Ages these remedies were used for fever and rheumatism by Hildegard of Bingen and Henrik Harpestreng. The first "clinical trial" was reported by Edward Stone in 1763 with a successful treatment of malarial fever with the willow bark. In 1876 the antirheumatic effect of salicin was described by T. MacLagan, and that of salicylic acid by S. Stricker and L. Riess. Acetylsalicylic acid was synthesized by Charles Gerhardt in 1853 and in 1897 by Felix Hoffmann in the Bayer Company. The beneficial effect of acetylsalicylic acid (Aspirin) on pain and rheumatic fever was recognized by K. Witthauer and J. Wohlgemuth, and the mechanism of action was explained in 1971 by John Vane. Today the antithrombotic effect of acetylsalicylic acid and new aspects of ongoing research demonstrates a still living drug.</div>
</front>
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<Title>Dansk medicinhistorisk arbog</Title>
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<ArticleTitle>[From willow bark to acetylsalicylic acid].</ArticleTitle>
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<Abstract><AbstractText>Acetylsalicylic acid is one of the most widely used drugs in the world. Its ancestry the salicylates, including salicin and salicylic acid, are found in the bark and leaves of the willow and poplar trees. The ancient Sumerians and Egyptians, as well as Hippocrates, Celsus, Pliny the Elder, Dioscorides and Galen used these natural products as remedies for pain, fever and inflammation. In the Middle Ages these remedies were used for fever and rheumatism by Hildegard of Bingen and Henrik Harpestreng. The first "clinical trial" was reported by Edward Stone in 1763 with a successful treatment of malarial fever with the willow bark. In 1876 the antirheumatic effect of salicin was described by T. MacLagan, and that of salicylic acid by S. Stricker and L. Riess. Acetylsalicylic acid was synthesized by Charles Gerhardt in 1853 and in 1897 by Felix Hoffmann in the Bayer Company. The beneficial effect of acetylsalicylic acid (Aspirin) on pain and rheumatic fever was recognized by K. Witthauer and J. Wohlgemuth, and the mechanism of action was explained in 1971 by John Vane. Today the antithrombotic effect of acetylsalicylic acid and new aspects of ongoing research demonstrates a still living drug.</AbstractText>
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