A paralogous decoy protects Phytophthora sojae apoplastic effector PsXEG1 from a host inhibitor.
Identifieur interne : 000A60 ( Main/Corpus ); précédent : 000A59; suivant : 000A61A paralogous decoy protects Phytophthora sojae apoplastic effector PsXEG1 from a host inhibitor.
Auteurs : Zhenchuan Ma ; Lin Zhu ; Tianqiao Song ; Yang Wang ; Qi Zhang ; Yeqiang Xia ; Min Qiu ; Yachun Lin ; Haiyang Li ; Liang Kong ; Yufeng Fang ; Wenwu Ye ; Yan Wang ; Suomeng Dong ; Xiaobo Zheng ; Brett M. Tyler ; Yuanchao WangSource :
- Science (New York, N.Y.) [ 1095-9203 ] ; 2017.
English descriptors
- KwdEn :
- Cellulase (antagonists & inhibitors), Cellulase (genetics), Cellulase (metabolism), Extracellular Space (parasitology), Glucans (metabolism), Host-Pathogen Interactions (MeSH), Phytophthora (enzymology), Phytophthora (genetics), Phytophthora (pathogenicity), Plant Diseases (parasitology), Plant Proteins (genetics), Plant Proteins (metabolism), Protein Binding (MeSH), Soybeans (enzymology), Soybeans (genetics), Soybeans (parasitology), Virulence (MeSH), Xylans (metabolism).
- MESH :
- chemical , antagonists & inhibitors : Cellulase.
- chemical , genetics : Cellulase, Plant Proteins.
- chemical , metabolism : Cellulase, Glucans, Plant Proteins, Xylans.
- enzymology : Phytophthora, Soybeans.
- genetics : Phytophthora, Soybeans.
- parasitology : Extracellular Space, Plant Diseases, Soybeans.
- pathogenicity : Phytophthora.
- Host-Pathogen Interactions, Protein Binding, Virulence.
Abstract
The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the Phytophthora sojae-soybean interaction. We show that soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. P. sojae, however, secretes a paralogous PsXEG1-like protein, PsXLP1, that has lost enzyme activity but binds to GmGIP1 more tightly than does PsXEG1, thus freeing PsXEG1 to support P. sojae infection. The gene pair encoding PsXEG1 and PsXLP1 is conserved in many Phytophthora species, and the P. parasitica orthologs PpXEG1 and PpXLP1 have similar functions. Thus, this apoplastic decoy strategy may be widely used in Phytophthora pathosystems.
DOI: 10.1126/science.aai7919
PubMed: 28082413
Links to Exploration step
pubmed:28082413Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A paralogous decoy protects <i>Phytophthora sojae</i> apoplastic effector PsXEG1 from a host inhibitor.</title><author><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhu, Lin" sort="Zhu, Lin" uniqKey="Zhu L" first="Lin" last="Zhu">Lin Zhu</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Song, Tianqiao" sort="Song, Tianqiao" uniqKey="Song T" first="Tianqiao" last="Song">Tianqiao Song</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yang" sort="Wang, Yang" uniqKey="Wang Y" first="Yang" last="Wang">Yang Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Xia, Yeqiang" sort="Xia, Yeqiang" uniqKey="Xia Y" first="Yeqiang" last="Xia">Yeqiang Xia</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Haiyang" sort="Li, Haiyang" uniqKey="Li H" first="Haiyang" last="Li">Haiyang Li</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Kong, Liang" sort="Kong, Liang" uniqKey="Kong L" first="Liang" last="Kong">Liang Kong</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Fang, Yufeng" sort="Fang, Yufeng" uniqKey="Fang Y" first="Yufeng" last="Fang">Yufeng Fang</name><affiliation><nlm:affiliation>Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name><affiliation><nlm:affiliation>Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China. wangyc@njau.edu.cn.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28082413</idno><idno type="pmid">28082413</idno><idno type="doi">10.1126/science.aai7919</idno><idno type="wicri:Area/Main/Corpus">000A60</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000A60</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A paralogous decoy protects <i>Phytophthora sojae</i> apoplastic effector PsXEG1 from a host inhibitor.</title><author><name sortKey="Ma, Zhenchuan" sort="Ma, Zhenchuan" uniqKey="Ma Z" first="Zhenchuan" last="Ma">Zhenchuan Ma</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhu, Lin" sort="Zhu, Lin" uniqKey="Zhu L" first="Lin" last="Zhu">Lin Zhu</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Song, Tianqiao" sort="Song, Tianqiao" uniqKey="Song T" first="Tianqiao" last="Song">Tianqiao Song</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yang" sort="Wang, Yang" uniqKey="Wang Y" first="Yang" last="Wang">Yang Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zhang, Qi" sort="Zhang, Qi" uniqKey="Zhang Q" first="Qi" last="Zhang">Qi Zhang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Xia, Yeqiang" sort="Xia, Yeqiang" uniqKey="Xia Y" first="Yeqiang" last="Xia">Yeqiang Xia</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Qiu, Min" sort="Qiu, Min" uniqKey="Qiu M" first="Min" last="Qiu">Min Qiu</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Lin, Yachun" sort="Lin, Yachun" uniqKey="Lin Y" first="Yachun" last="Lin">Yachun Lin</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Li, Haiyang" sort="Li, Haiyang" uniqKey="Li H" first="Haiyang" last="Li">Haiyang Li</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Kong, Liang" sort="Kong, Liang" uniqKey="Kong L" first="Liang" last="Kong">Liang Kong</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Fang, Yufeng" sort="Fang, Yufeng" uniqKey="Fang Y" first="Yufeng" last="Fang">Yufeng Fang</name><affiliation><nlm:affiliation>Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Ye, Wenwu" sort="Ye, Wenwu" uniqKey="Ye W" first="Wenwu" last="Ye">Wenwu Ye</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yan" sort="Wang, Yan" uniqKey="Wang Y" first="Yan" last="Wang">Yan Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Dong, Suomeng" sort="Dong, Suomeng" uniqKey="Dong S" first="Suomeng" last="Dong">Suomeng Dong</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Zheng, Xiaobo" sort="Zheng, Xiaobo" uniqKey="Zheng X" first="Xiaobo" last="Zheng">Xiaobo Zheng</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author><author><name sortKey="Tyler, Brett M" sort="Tyler, Brett M" uniqKey="Tyler B" first="Brett M" last="Tyler">Brett M. Tyler</name><affiliation><nlm:affiliation>Center for Genome Research and Biocomputing and Department of Botany and Plant Pathology, Oregon State University, Corvallis, OR 97331, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Wang, Yuanchao" sort="Wang, Yuanchao" uniqKey="Wang Y" first="Yuanchao" last="Wang">Yuanchao Wang</name><affiliation><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China. wangyc@njau.edu.cn.</nlm:affiliation></affiliation><affiliation><nlm:affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Science (New York, N.Y.)</title><idno type="eISSN">1095-9203</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cellulase (antagonists & inhibitors)</term><term>Cellulase (genetics)</term><term>Cellulase (metabolism)</term><term>Extracellular Space (parasitology)</term><term>Glucans (metabolism)</term><term>Host-Pathogen Interactions (MeSH)</term><term>Phytophthora (enzymology)</term><term>Phytophthora (genetics)</term><term>Phytophthora (pathogenicity)</term><term>Plant Diseases (parasitology)</term><term>Plant Proteins (genetics)</term><term>Plant Proteins (metabolism)</term><term>Protein Binding (MeSH)</term><term>Soybeans (enzymology)</term><term>Soybeans (genetics)</term><term>Soybeans (parasitology)</term><term>Virulence (MeSH)</term><term>Xylans (metabolism)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="antagonists & inhibitors" xml:lang="en"><term>Cellulase</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Cellulase</term><term>Plant Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Cellulase</term><term>Glucans</term><term>Plant Proteins</term><term>Xylans</term></keywords><keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Phytophthora</term><term>Soybeans</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Phytophthora</term><term>Soybeans</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Extracellular Space</term><term>Plant Diseases</term><term>Soybeans</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Phytophthora</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Host-Pathogen Interactions</term><term>Protein Binding</term><term>Virulence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the <i>Phytophthora sojae</i>-soybean interaction. We show that soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. <i>P. sojae</i>, however, secretes a paralogous PsXEG1-like protein, PsXLP1, that has lost enzyme activity but binds to GmGIP1 more tightly than does PsXEG1, thus freeing PsXEG1 to support <i>P. sojae</i> infection. The gene pair encoding PsXEG1 and PsXLP1 is conserved in many <i>Phytophthora</i> species, and the <i>P. parasitica</i> orthologs PpXEG1 and PpXLP1 have similar functions. Thus, this apoplastic decoy strategy may be widely used in <i>Phytophthora</i> pathosystems.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">28082413</PMID><DateCompleted><Year>2017</Year><Month>09</Month><Day>20</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1095-9203</ISSN><JournalIssue CitedMedium="Internet"><Volume>355</Volume><Issue>6326</Issue><PubDate><Year>2017</Year><Month>02</Month><Day>17</Day></PubDate></JournalIssue><Title>Science (New York, N.Y.)</Title><ISOAbbreviation>Science</ISOAbbreviation></Journal><ArticleTitle>A paralogous decoy protects <i>Phytophthora sojae</i> apoplastic effector PsXEG1 from a host inhibitor.</ArticleTitle><Pagination><MedlinePgn>710-714</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1126/science.aai7919</ELocationID><Abstract><AbstractText>The extracellular space (apoplast) of plant tissue represents a critical battleground between plants and attacking microbes. Here we show that a pathogen-secreted apoplastic xyloglucan-specific endoglucanase, PsXEG1, is a focus of this struggle in the <i>Phytophthora sojae</i>-soybean interaction. We show that soybean produces an apoplastic glucanase inhibitor protein, GmGIP1, that binds to PsXEG1 to block its contribution to virulence. <i>P. sojae</i>, however, secretes a paralogous PsXEG1-like protein, PsXLP1, that has lost enzyme activity but binds to GmGIP1 more tightly than does PsXEG1, thus freeing PsXEG1 to support <i>P. sojae</i> infection. The gene pair encoding PsXEG1 and PsXLP1 is conserved in many <i>Phytophthora</i> species, and the <i>P. parasitica</i> orthologs PpXEG1 and PpXLP1 have similar functions. Thus, this apoplastic decoy strategy may be widely used in <i>Phytophthora</i> pathosystems.</AbstractText><CopyrightInformation>Copyright © 2017, American Association for the Advancement of Science.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ma</LastName><ForeName>Zhenchuan</ForeName><Initials>Z</Initials><Identifier Source="ORCID">0000-0002-8478-2833</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhu</LastName><ForeName>Lin</ForeName><Initials>L</Initials><Identifier Source="ORCID">0000-0003-1460-8415</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Song</LastName><ForeName>Tianqiao</ForeName><Initials>T</Initials><Identifier Source="ORCID">0000-0002-4946-6149</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Yang</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0001-9101-2899</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Qi</ForeName><Initials>Q</Initials><Identifier Source="ORCID">0000-0003-2463-764X</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Xia</LastName><ForeName>Yeqiang</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0001-9016-7610</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Qiu</LastName><ForeName>Min</ForeName><Initials>M</Initials><Identifier Source="ORCID">0000-0001-9493-3044</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lin</LastName><ForeName>Yachun</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0001-7353-8918</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Haiyang</ForeName><Initials>H</Initials><Identifier Source="ORCID">0000-0002-8205-4875</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kong</LastName><ForeName>Liang</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of 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ValidYN="Y"><LastName>Wang</LastName><ForeName>Yan</ForeName><Initials>Y</Initials><Identifier Source="ORCID">0000-0001-7465-5518</Identifier><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dong</LastName><ForeName>Suomeng</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author><Author 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Pathology, Nanjing Agricultural University, Nanjing 210095, China. wangyc@njau.edu.cn.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing 210095, China.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013486">Research Support, U.S. Gov't, Non-P.H.S.</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2017</Year><Month>01</Month><Day>12</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Science</MedlineTA><NlmUniqueID>0404511</NlmUniqueID><ISSNLinking>0036-8075</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance 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PubStatus="accepted"><Year>2016</Year><Month>12</Month><Day>28</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2017</Year><Month>1</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2017</Year><Month>9</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2017</Year><Month>1</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28082413</ArticleId><ArticleId IdType="pii">science.aai7919</ArticleId><ArticleId IdType="doi">10.1126/science.aai7919</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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