Calcium-vitamin D-fortified milk is as effective on circulating bone biomarkers as fortified juice and supplement but has less acceptance: a randomised controlled school-based trial.
Identifieur interne : 000271 ( PubMed/Curation ); précédent : 000270; suivant : 000272Calcium-vitamin D-fortified milk is as effective on circulating bone biomarkers as fortified juice and supplement but has less acceptance: a randomised controlled school-based trial.
Auteurs : T R Neyestani [Iran] ; M. Hajifaraji ; N. Omidvar ; B. Nikooyeh ; M R Eshraghian ; N. Shariatzadeh ; A. Kalayi ; N. Khalaji ; M. Zahedirad ; M. Abtahi ; S. AsadzadehSource :
- Journal of human nutrition and dietetics : the official journal of the British Dietetic Association [ 1365-277X ] ; 2014.
English descriptors
- KwdEn :
- Animals, Beverages, Biomarkers (blood), Bone and Bones, Calcium, Dietary (administration & dosage), Calcium, Dietary (pharmacology), Child, Cholecalciferol (blood), Citrus sinensis, Dietary Supplements, Female, Food Preferences, Food, Fortified, Humans, Male, Milk, Nutritional Status, Osteocalcin (blood), Parathyroid Hormone (blood), Trace Elements (administration & dosage), Trace Elements (pharmacology), Vitamin D (administration & dosage), Vitamin D (blood), Vitamin D (pharmacology), Vitamin D Deficiency (blood), Vitamin D Deficiency (prevention & control), Vitamins (administration & dosage), Vitamins (blood), Vitamins (pharmacology).
- MESH :
- chemical , administration & dosage : Calcium, Dietary, Trace Elements, Vitamin D, Vitamins.
- chemical , blood : Biomarkers, Cholecalciferol, Osteocalcin, Parathyroid Hormone, Vitamin D, Vitamins.
- chemical , pharmacology : Calcium, Dietary, Trace Elements, Vitamin D, Vitamins.
- blood : Vitamin D Deficiency.
- prevention & control : Vitamin D Deficiency.
- Animals, Beverages, Bone and Bones, Child, Citrus sinensis, Dietary Supplements, Female, Food Preferences, Food, Fortified, Humans, Male, Milk, Nutritional Status.
Abstract
Hypovitaminosis D, especially during cold seasons, is quite prevalent among primary school children in Tehran. The present study aimed to compare the efficacy of calcium-vitamin D-fortified-milk, -orange juice and supplement in primary school children.
DOI: 10.1111/jhn.12191
PubMed: 24267005
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Hajifaraji</name></author><author><name sortKey="Omidvar, N" sort="Omidvar, N" uniqKey="Omidvar N" first="N" last="Omidvar">N. Omidvar</name></author><author><name sortKey="Nikooyeh, B" sort="Nikooyeh, B" uniqKey="Nikooyeh B" first="B" last="Nikooyeh">B. Nikooyeh</name></author><author><name sortKey="Eshraghian, M R" sort="Eshraghian, M R" uniqKey="Eshraghian M" first="M R" last="Eshraghian">M R Eshraghian</name></author><author><name sortKey="Shariatzadeh, N" sort="Shariatzadeh, N" uniqKey="Shariatzadeh N" first="N" last="Shariatzadeh">N. Shariatzadeh</name></author><author><name sortKey="Kalayi, A" sort="Kalayi, A" uniqKey="Kalayi A" first="A" last="Kalayi">A. Kalayi</name></author><author><name sortKey="Khalaji, N" sort="Khalaji, N" uniqKey="Khalaji N" first="N" last="Khalaji">N. Khalaji</name></author><author><name sortKey="Zahedirad, M" sort="Zahedirad, M" uniqKey="Zahedirad M" first="M" last="Zahedirad">M. Zahedirad</name></author><author><name sortKey="Abtahi, M" sort="Abtahi, M" uniqKey="Abtahi M" first="M" last="Abtahi">M. Abtahi</name></author><author><name sortKey="Asadzadeh, S" sort="Asadzadeh, S" uniqKey="Asadzadeh S" first="S" last="Asadzadeh">S. 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Hajifaraji</name></author><author><name sortKey="Omidvar, N" sort="Omidvar, N" uniqKey="Omidvar N" first="N" last="Omidvar">N. Omidvar</name></author><author><name sortKey="Nikooyeh, B" sort="Nikooyeh, B" uniqKey="Nikooyeh B" first="B" last="Nikooyeh">B. Nikooyeh</name></author><author><name sortKey="Eshraghian, M R" sort="Eshraghian, M R" uniqKey="Eshraghian M" first="M R" last="Eshraghian">M R Eshraghian</name></author><author><name sortKey="Shariatzadeh, N" sort="Shariatzadeh, N" uniqKey="Shariatzadeh N" first="N" last="Shariatzadeh">N. Shariatzadeh</name></author><author><name sortKey="Kalayi, A" sort="Kalayi, A" uniqKey="Kalayi A" first="A" last="Kalayi">A. Kalayi</name></author><author><name sortKey="Khalaji, N" sort="Khalaji, N" uniqKey="Khalaji N" first="N" last="Khalaji">N. Khalaji</name></author><author><name sortKey="Zahedirad, M" sort="Zahedirad, M" uniqKey="Zahedirad M" first="M" last="Zahedirad">M. Zahedirad</name></author><author><name sortKey="Abtahi, M" sort="Abtahi, M" uniqKey="Abtahi M" first="M" last="Abtahi">M. Abtahi</name></author><author><name sortKey="Asadzadeh, S" sort="Asadzadeh, S" uniqKey="Asadzadeh S" first="S" last="Asadzadeh">S. Asadzadeh</name></author></analytic><series><title level="j">Journal of human nutrition and dietetics : the official journal of the British Dietetic Association</title><idno type="eISSN">1365-277X</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Beverages</term><term>Biomarkers (blood)</term><term>Bone and Bones</term><term>Calcium, Dietary (administration & dosage)</term><term>Calcium, Dietary (pharmacology)</term><term>Child</term><term>Cholecalciferol (blood)</term><term>Citrus sinensis</term><term>Dietary Supplements</term><term>Female</term><term>Food Preferences</term><term>Food, Fortified</term><term>Humans</term><term>Male</term><term>Milk</term><term>Nutritional Status</term><term>Osteocalcin (blood)</term><term>Parathyroid Hormone (blood)</term><term>Trace Elements (administration & dosage)</term><term>Trace Elements (pharmacology)</term><term>Vitamin D (administration & dosage)</term><term>Vitamin D (blood)</term><term>Vitamin D (pharmacology)</term><term>Vitamin D Deficiency (blood)</term><term>Vitamin D Deficiency (prevention & control)</term><term>Vitamins (administration & dosage)</term><term>Vitamins (blood)</term><term>Vitamins (pharmacology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Calcium, Dietary</term><term>Trace Elements</term><term>Vitamin D</term><term>Vitamins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term><term>Cholecalciferol</term><term>Osteocalcin</term><term>Parathyroid Hormone</term><term>Vitamin D</term><term>Vitamins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Calcium, Dietary</term><term>Trace Elements</term><term>Vitamin D</term><term>Vitamins</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Vitamin D Deficiency</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Vitamin D Deficiency</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Beverages</term><term>Bone and Bones</term><term>Child</term><term>Citrus sinensis</term><term>Dietary Supplements</term><term>Female</term><term>Food Preferences</term><term>Food, Fortified</term><term>Humans</term><term>Male</term><term>Milk</term><term>Nutritional Status</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Hypovitaminosis D, especially during cold seasons, is quite prevalent among primary school children in Tehran. The present study aimed to compare the efficacy of calcium-vitamin D-fortified-milk, -orange juice and supplement in primary school children.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">24267005</PMID><DateCreated><Year>2014</Year><Month>11</Month><Day>27</Day></DateCreated><DateCompleted><Year>2015</Year><Month>07</Month><Day>09</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1365-277X</ISSN><JournalIssue CitedMedium="Internet"><Volume>27</Volume><Issue>6</Issue><PubDate><Year>2014</Year><Month>Dec</Month></PubDate></JournalIssue><Title>Journal of human nutrition and dietetics : the official journal of the British Dietetic Association</Title><ISOAbbreviation>J Hum Nutr Diet</ISOAbbreviation></Journal><ArticleTitle>Calcium-vitamin D-fortified milk is as effective on circulating bone biomarkers as fortified juice and supplement but has less acceptance: a randomised controlled school-based trial.</ArticleTitle><Pagination><MedlinePgn>606-16</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1111/jhn.12191</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Hypovitaminosis D, especially during cold seasons, is quite prevalent among primary school children in Tehran. The present study aimed to compare the efficacy of calcium-vitamin D-fortified-milk, -orange juice and supplement in primary school children.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Children aged 9-12 years from both sexes were randomly assigned to one of six groups to receive plain milk, fortified milk, plain orange juice, fortified orange juice, supplement or placebo. Both fortified-milk and -juice contained 100 IU of vitamin D and 500 mg of calcium per 200 mL package, whereas supplement contained 200 IU of vitamin D and 500 mg of calcium. The duration of intervention was 12 weeks, from November 2008 to March 2009.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">A total of 410 children completed the study. Regression analysis with adjustment for both sex and initial values of 25(OH)D revealed that consumption of either supplement, fortified orange juice or fortified milk resulted in a 20.8 nm [confidence interval (CI) = 17.4-23.9], 9.9 nm (CI = 7.4-12.3) or 6.9 nm (CI = 3.3-10.5) increase in circulating 25(OH)D compared to the related control groups. However, changes in serum osteocalcin and intact parathyroid hormone in the supplement group did not differ from those of fortified milk or plain milk. The increment of osteocalcin in both plain milk and fortified milk was more than in fortified orange juice, although the difference was statistically insignificant.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Despite having double amount of vitamin D and being more effective in raising serum 25(OH)D, supplementation did not confer additional benefit in terms of osteocalcin and intact parathyroid hormone compared to either fortified or plain milk.</AbstractText><CopyrightInformation>© 2013 The British Dietetic Association Ltd.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Neyestani</LastName><ForeName>T R</ForeName><Initials>TR</Initials><AffiliationInfo><Affiliation>Department of Nutrition Research, National Nutrition and Food Technology Research Institute (NNFTRI), Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hajifaraji</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Omidvar</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Nikooyeh</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Eshraghian</LastName><ForeName>M R</ForeName><Initials>MR</Initials></Author><Author ValidYN="Y"><LastName>Shariatzadeh</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Kalayi</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Khalaji</LastName><ForeName>N</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Zahedirad</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Abtahi</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Asadzadeh</LastName><ForeName>S</ForeName><Initials>S</Initials></Author></AuthorList><Language>ENG</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>Nov</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Hum Nutr Diet</MedlineTA><NlmUniqueID>8904840</NlmUniqueID><ISSNLinking>0952-3871</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D002136">Calcium, Dietary</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010281">Parathyroid Hormone</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014131">Trace Elements</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D014815">Vitamins</NameOfSubstance></Chemical><Chemical><RegistryNumber>104982-03-8</RegistryNumber><NameOfSubstance UI="D015675">Osteocalcin</NameOfSubstance></Chemical><Chemical><RegistryNumber>1406-16-2</RegistryNumber><NameOfSubstance UI="D014807">Vitamin D</NameOfSubstance></Chemical><Chemical><RegistryNumber>1C6V77QF41</RegistryNumber><NameOfSubstance UI="D002762">Cholecalciferol</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001628" MajorTopicYN="Y">Beverages</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001842" MajorTopicYN="Y">Bone and Bones</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002136" MajorTopicYN="N">Calcium, Dietary</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002762" MajorTopicYN="N">Cholecalciferol</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032084" MajorTopicYN="N">Citrus sinensis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019587" MajorTopicYN="Y">Dietary Supplements</DescriptorName></MeshHeading><MeshHeading><DescriptorName 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MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014131" MajorTopicYN="N">Trace Elements</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014807" MajorTopicYN="N">Vitamin D</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014808" MajorTopicYN="N">Vitamin D Deficiency</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014815" MajorTopicYN="N">Vitamins</DescriptorName><QualifierName 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