Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices.
Identifieur interne : 000779 ( PubMed/Corpus ); précédent : 000778; suivant : 000780Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices.
Auteurs : R. Patel ; S. Chopra ; M. Vandeven ; D. CumminsSource :
- The Journal of clinical dentistry [ 0895-8831 ] ; 2011.
English descriptors
- KwdEn :
- Acetates (administration & dosage), Acetates (therapeutic use), Administration, Topical, Arginine (administration & dosage), Arginine (pharmacology), Beverages, Calcium Carbonate (administration & dosage), Calcium Carbonate (pharmacology), Citric Acid (pharmacology), Citrus paradisi, Citrus sinensis, Dentifrices (administration & dosage), Dentifrices (pharmacology), Dentin (drug effects), Dentin Desensitizing Agents (administration & dosage), Dentin Desensitizing Agents (pharmacology), Dentin Permeability (drug effects), Dentinal Fluid (drug effects), Drug Combinations, Fluorides (administration & dosage), Fluorides (therapeutic use), Fruit, Humans, Hydrodynamics, Materials Testing, Phosphates (administration & dosage), Phosphates (therapeutic use), Single-Blind Method, Sodium Fluoride (administration & dosage), Sodium Fluoride (therapeutic use), Strontium (administration & dosage), Strontium (therapeutic use), Toothbrushing (instrumentation).
- MESH :
- chemical , administration & dosage : Acetates, Arginine, Calcium Carbonate, Dentifrices, Dentin Desensitizing Agents, Fluorides, Phosphates, Sodium Fluoride, Strontium.
- chemical , pharmacology : Arginine, Calcium Carbonate, Citric Acid, Dentifrices, Dentin Desensitizing Agents.
- chemical , therapeutic use : Acetates, Fluorides, Phosphates, Sodium Fluoride, Strontium.
- drug effects : Dentin, Dentin Permeability, Dentinal Fluid.
- instrumentation : Toothbrushing.
- Administration, Topical, Beverages, Citrus paradisi, Citrus sinensis, Drug Combinations, Fruit, Humans, Hydrodynamics, Materials Testing, Single-Blind Method.
Abstract
The in vitro effects of two commercial sensitivity relief dentifrices, one containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (MFP), and the other containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride, in occluding dentin tubules and reducing dentin fluid flow were compared in a blinded study using hydraulic conductance (Flodec).
PubMed: 22403986
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pubmed:22403986Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices.</title><author><name sortKey="Patel, R" sort="Patel, R" uniqKey="Patel R" first="R" last="Patel">R. Patel</name><affiliation><nlm:affiliation>Colgate-Palmolive Technology Center, Piscataway, NJ, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chopra, S" sort="Chopra, S" uniqKey="Chopra S" first="S" last="Chopra">S. Chopra</name></author><author><name sortKey="Vandeven, M" sort="Vandeven, M" uniqKey="Vandeven M" first="M" last="Vandeven">M. Vandeven</name></author><author><name sortKey="Cummins, D" sort="Cummins, D" uniqKey="Cummins D" first="D" last="Cummins">D. Cummins</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2011">2011</date><idno type="RBID">pubmed:22403986</idno><idno type="pmid">22403986</idno><idno type="wicri:Area/PubMed/Corpus">000779</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices.</title><author><name sortKey="Patel, R" sort="Patel, R" uniqKey="Patel R" first="R" last="Patel">R. Patel</name><affiliation><nlm:affiliation>Colgate-Palmolive Technology Center, Piscataway, NJ, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Chopra, S" sort="Chopra, S" uniqKey="Chopra S" first="S" last="Chopra">S. Chopra</name></author><author><name sortKey="Vandeven, M" sort="Vandeven, M" uniqKey="Vandeven M" first="M" last="Vandeven">M. Vandeven</name></author><author><name sortKey="Cummins, D" sort="Cummins, D" uniqKey="Cummins D" first="D" last="Cummins">D. Cummins</name></author></analytic><series><title level="j">The Journal of clinical dentistry</title><idno type="ISSN">0895-8831</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acetates (administration & dosage)</term><term>Acetates (therapeutic use)</term><term>Administration, Topical</term><term>Arginine (administration & dosage)</term><term>Arginine (pharmacology)</term><term>Beverages</term><term>Calcium Carbonate (administration & dosage)</term><term>Calcium Carbonate (pharmacology)</term><term>Citric Acid (pharmacology)</term><term>Citrus paradisi</term><term>Citrus sinensis</term><term>Dentifrices (administration & dosage)</term><term>Dentifrices (pharmacology)</term><term>Dentin (drug effects)</term><term>Dentin Desensitizing Agents (administration & dosage)</term><term>Dentin Desensitizing Agents (pharmacology)</term><term>Dentin Permeability (drug effects)</term><term>Dentinal Fluid (drug effects)</term><term>Drug Combinations</term><term>Fluorides (administration & dosage)</term><term>Fluorides (therapeutic use)</term><term>Fruit</term><term>Humans</term><term>Hydrodynamics</term><term>Materials Testing</term><term>Phosphates (administration & dosage)</term><term>Phosphates (therapeutic use)</term><term>Single-Blind Method</term><term>Sodium Fluoride (administration & dosage)</term><term>Sodium Fluoride (therapeutic use)</term><term>Strontium (administration & dosage)</term><term>Strontium (therapeutic use)</term><term>Toothbrushing (instrumentation)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Acetates</term><term>Arginine</term><term>Calcium Carbonate</term><term>Dentifrices</term><term>Dentin Desensitizing Agents</term><term>Fluorides</term><term>Phosphates</term><term>Sodium Fluoride</term><term>Strontium</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Arginine</term><term>Calcium Carbonate</term><term>Citric Acid</term><term>Dentifrices</term><term>Dentin Desensitizing Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Acetates</term><term>Fluorides</term><term>Phosphates</term><term>Sodium Fluoride</term><term>Strontium</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Dentin</term><term>Dentin Permeability</term><term>Dentinal Fluid</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Toothbrushing</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Topical</term><term>Beverages</term><term>Citrus paradisi</term><term>Citrus sinensis</term><term>Drug Combinations</term><term>Fruit</term><term>Humans</term><term>Hydrodynamics</term><term>Materials Testing</term><term>Single-Blind Method</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The in vitro effects of two commercial sensitivity relief dentifrices, one containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (MFP), and the other containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride, in occluding dentin tubules and reducing dentin fluid flow were compared in a blinded study using hydraulic conductance (Flodec).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22403986</PMID><DateCreated><Year>2012</Year><Month>3</Month><Day>12</Day></DateCreated><DateCompleted><Year>2012</Year><Month>04</Month><Day>05</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0895-8831</ISSN><JournalIssue CitedMedium="Print"><Volume>22</Volume><Issue>4</Issue><PubDate><Year>2011</Year></PubDate></JournalIssue><Title>The Journal of clinical dentistry</Title><ISOAbbreviation>J Clin Dent</ISOAbbreviation></Journal><ArticleTitle>Comparison of the effects on dentin permeability of two commercially available sensitivity relief dentifrices.</ArticleTitle><Pagination><MedlinePgn>108-12</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The in vitro effects of two commercial sensitivity relief dentifrices, one containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (MFP), and the other containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride, in occluding dentin tubules and reducing dentin fluid flow were compared in a blinded study using hydraulic conductance (Flodec).</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Human dentin segments were cut from extracted molars, mounted on acrylic blocks, etched, and connected to a Flodec to measure hydraulic conductance. Segments were divided into two groups (n = 6) and treated for one minute with either the arginine/calcium carbonate dentifrice or the strontium acetate dentifrice. The blocks were rinsed, connected to the Flodec, and the conductance was measured. Blocks were rinsed again and incubated in phosphate-buffered saline (PBS) for at least two hours before the next treatment. The cycle was repeated for a total of three treatments (one using a fingertip and the next two using a toothbrush). After the third treatment, the blocks were incubated in PBS overnight and conductance was re-measured. The two groups were further divided into three sets of two segments each, which were challenged for one minute with either 6% citric acid, orange juice, or grapefruit juice.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The hydraulic conductance study showed that the dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride provided a significantly higher percentage reduction in fluid flow immediately after fingertip application, as well as after two brushing cycles, compared to the dentifrice containing 8% strontium acetate and 1040 ppm fluoride. After various acid challenges, the percentage reduction in fluid flow of dentin treated with the arginine/calcium carbonate dentifrice remained significantly higher than that of the strontium acetate dentifrice. These results are highly consistent with the results from an independent clinical study which showed that the arginine/calcium carbonate dentifrice provided dentin hypersensitivity relief immediately after direct topical application with a fingertip and massage for one minute per sensitive tooth, whereas the strontium acetate dentifrice did not.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Based on this in vitro hydraulic conductance study, the dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride was significantly more effective in reducing fluid flow through dentin tubules as a result of occlusion than the dentifrice containing 8% strontium acetate and 1040 ppm fluoride. Further, the superior occlusion obtained with the arginine/calcium carbonate dentifrice was resistant to acid challenge.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Patel</LastName><ForeName>R</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>Colgate-Palmolive Technology Center, Piscataway, NJ, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chopra</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Vandeven</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Cummins</LastName><ForeName>D</ForeName><Initials>D</Initials></Author></AuthorList><Language>ENG</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Clin Dent</MedlineTA><NlmUniqueID>8904411</NlmUniqueID><ISSNLinking>0895-8831</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000085">Acetates</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D003802">Dentifrices</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D057133">Dentin Desensitizing Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D004338">Drug Combinations</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010710">Phosphates</NameOfSubstance></Chemical><Chemical><RegistryNumber>15181-43-8</RegistryNumber><NameOfSubstance UI="C012980">fluorophosphate</NameOfSubstance></Chemical><Chemical><RegistryNumber>2968PHW8QP</RegistryNumber><NameOfSubstance UI="D019343">Citric Acid</NameOfSubstance></Chemical><Chemical><RegistryNumber>4SL32YMY7B</RegistryNumber><NameOfSubstance UI="C106741">strontium acetate</NameOfSubstance></Chemical><Chemical><RegistryNumber>8ZYQ1474W7</RegistryNumber><NameOfSubstance UI="D012969">Sodium Fluoride</NameOfSubstance></Chemical><Chemical><RegistryNumber>94ZLA3W45F</RegistryNumber><NameOfSubstance UI="D001120">Arginine</NameOfSubstance></Chemical><Chemical><RegistryNumber>H0G9379FGK</RegistryNumber><NameOfSubstance UI="D002119">Calcium Carbonate</NameOfSubstance></Chemical><Chemical><RegistryNumber>Q80VPU408O</RegistryNumber><NameOfSubstance UI="D005459">Fluorides</NameOfSubstance></Chemical><Chemical><RegistryNumber>YZS2RPE8LE</RegistryNumber><NameOfSubstance UI="D013324">Strontium</NameOfSubstance></Chemical></ChemicalList><CitationSubset>D</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000085" MajorTopicYN="N">Acetates</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000287" MajorTopicYN="N">Administration, Topical</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001120" MajorTopicYN="N">Arginine</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001628" MajorTopicYN="N">Beverages</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002119" MajorTopicYN="N">Calcium Carbonate</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019343" MajorTopicYN="N">Citric Acid</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D032083" MajorTopicYN="N">Citrus paradisi</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D032084" MajorTopicYN="N">Citrus sinensis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003802" MajorTopicYN="N">Dentifrices</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003804" MajorTopicYN="N">Dentin</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D057133" MajorTopicYN="N">Dentin Desensitizing Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003806" MajorTopicYN="N">Dentin Permeability</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D019234" MajorTopicYN="N">Dentinal Fluid</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004338" MajorTopicYN="N">Drug Combinations</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005459" MajorTopicYN="N">Fluorides</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005638" MajorTopicYN="N">Fruit</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D057446" MajorTopicYN="N">Hydrodynamics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008422" MajorTopicYN="N">Materials Testing</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010710" MajorTopicYN="N">Phosphates</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016037" MajorTopicYN="N">Single-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012969" MajorTopicYN="N">Sodium Fluoride</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013324" MajorTopicYN="N">Strontium</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014099" MajorTopicYN="N">Toothbrushing</DescriptorName><QualifierName UI="Q000295" MajorTopicYN="N">instrumentation</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2012</Year><Month>3</Month><Day>13</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>4</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22403986</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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