Perioperative effects of oral midazolam premedication in children undergoing skin laser treatment. A double-blinded randomized placebo-controlled trial.
Identifieur interne : 000682 ( PubMed/Checkpoint ); précédent : 000681; suivant : 000683Perioperative effects of oral midazolam premedication in children undergoing skin laser treatment. A double-blinded randomized placebo-controlled trial.
Auteurs : Mehrdad Shoroghi [Iran] ; Shahriyar Arbabi ; Farshid Farahbakhsh ; Mehrdad Sheikhvatan ; Ali AbbasiSource :
- Acta cirurgica brasileira [ 1678-2674 ] ; 2011.
English descriptors
- KwdEn :
- Administration, Oral, Beverages, Child, Child, Preschool, Citrus sinensis, Dermatologic Surgical Procedures, Double-Blind Method, Female, Hemodynamics (drug effects), Humans, Hypnotics and Sedatives (administration & dosage), Hypnotics and Sedatives (adverse effects), Laser Therapy, Male, Midazolam (administration & dosage), Midazolam (adverse effects), Perioperative Period, Preanesthetic Medication (adverse effects), Statistics, Nonparametric, Time Factors, Treatment Outcome.
- MESH :
- chemical , administration & dosage : Hypnotics and Sedatives, Midazolam.
- chemical , adverse effects : Hypnotics and Sedatives, Midazolam.
- adverse effects : Preanesthetic Medication.
- drug effects : Hemodynamics.
- Administration, Oral, Beverages, Child, Child, Preschool, Citrus sinensis, Dermatologic Surgical Procedures, Double-Blind Method, Female, Humans, Laser Therapy, Male, Perioperative Period, Statistics, Nonparametric, Time Factors, Treatment Outcome.
Abstract
To investigate and compare the efficacy of oral midazolam with two different dosages in orange juice on perioperative hemodynamics and behavioral changes in children who underwent skin laser treatment in an academic educational Hospital.
PubMed: 21808844
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Perioperative effects of oral midazolam premedication in children undergoing skin laser treatment. A double-blinded randomized placebo-controlled trial.</title><author><name sortKey="Shoroghi, Mehrdad" sort="Shoroghi, Mehrdad" uniqKey="Shoroghi M" first="Mehrdad" last="Shoroghi">Mehrdad Shoroghi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anaesthesia, Razi Hospital, Tehran University of Medical Sciences, Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>Department of Anaesthesia, Razi Hospital, Tehran University of Medical Sciences</wicri:regionArea><wicri:noRegion>Tehran University of Medical Sciences</wicri:noRegion></affiliation></author><author><name sortKey="Arbabi, Shahriyar" sort="Arbabi, Shahriyar" uniqKey="Arbabi S" first="Shahriyar" last="Arbabi">Shahriyar Arbabi</name></author><author><name sortKey="Farahbakhsh, Farshid" sort="Farahbakhsh, Farshid" uniqKey="Farahbakhsh F" first="Farshid" last="Farahbakhsh">Farshid Farahbakhsh</name></author><author><name sortKey="Sheikhvatan, Mehrdad" sort="Sheikhvatan, Mehrdad" uniqKey="Sheikhvatan M" first="Mehrdad" last="Sheikhvatan">Mehrdad Sheikhvatan</name></author><author><name sortKey="Abbasi, Ali" sort="Abbasi, Ali" uniqKey="Abbasi A" first="Ali" last="Abbasi">Ali Abbasi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2011">2011</date><idno type="RBID">pubmed:21808844</idno><idno type="pmid">21808844</idno><idno type="wicri:Area/PubMed/Corpus">000710</idno><idno type="wicri:Area/PubMed/Curation">000710</idno><idno type="wicri:Area/PubMed/Checkpoint">000710</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Perioperative effects of oral midazolam premedication in children undergoing skin laser treatment. A double-blinded randomized placebo-controlled trial.</title><author><name sortKey="Shoroghi, Mehrdad" sort="Shoroghi, Mehrdad" uniqKey="Shoroghi M" first="Mehrdad" last="Shoroghi">Mehrdad Shoroghi</name><affiliation wicri:level="1"><nlm:affiliation>Department of Anaesthesia, Razi Hospital, Tehran University of Medical Sciences, Iran.</nlm:affiliation><country xml:lang="fr">Iran</country><wicri:regionArea>Department of Anaesthesia, Razi Hospital, Tehran University of Medical Sciences</wicri:regionArea><wicri:noRegion>Tehran University of Medical Sciences</wicri:noRegion></affiliation></author><author><name sortKey="Arbabi, Shahriyar" sort="Arbabi, Shahriyar" uniqKey="Arbabi S" first="Shahriyar" last="Arbabi">Shahriyar Arbabi</name></author><author><name sortKey="Farahbakhsh, Farshid" sort="Farahbakhsh, Farshid" uniqKey="Farahbakhsh F" first="Farshid" last="Farahbakhsh">Farshid Farahbakhsh</name></author><author><name sortKey="Sheikhvatan, Mehrdad" sort="Sheikhvatan, Mehrdad" uniqKey="Sheikhvatan M" first="Mehrdad" last="Sheikhvatan">Mehrdad Sheikhvatan</name></author><author><name sortKey="Abbasi, Ali" sort="Abbasi, Ali" uniqKey="Abbasi A" first="Ali" last="Abbasi">Ali Abbasi</name></author></analytic><series><title level="j">Acta cirurgica brasileira</title><idno type="eISSN">1678-2674</idno><imprint><date when="2011" type="published">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Oral</term><term>Beverages</term><term>Child</term><term>Child, Preschool</term><term>Citrus sinensis</term><term>Dermatologic Surgical Procedures</term><term>Double-Blind Method</term><term>Female</term><term>Hemodynamics (drug effects)</term><term>Humans</term><term>Hypnotics and Sedatives (administration & dosage)</term><term>Hypnotics and Sedatives (adverse effects)</term><term>Laser Therapy</term><term>Male</term><term>Midazolam (administration & dosage)</term><term>Midazolam (adverse effects)</term><term>Perioperative Period</term><term>Preanesthetic Medication (adverse effects)</term><term>Statistics, Nonparametric</term><term>Time Factors</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Hypnotics and Sedatives</term><term>Midazolam</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Hypnotics and Sedatives</term><term>Midazolam</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Preanesthetic Medication</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Hemodynamics</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Beverages</term><term>Child</term><term>Child, Preschool</term><term>Citrus sinensis</term><term>Dermatologic Surgical Procedures</term><term>Double-Blind Method</term><term>Female</term><term>Humans</term><term>Laser Therapy</term><term>Male</term><term>Perioperative Period</term><term>Statistics, Nonparametric</term><term>Time Factors</term><term>Treatment Outcome</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To investigate and compare the efficacy of oral midazolam with two different dosages in orange juice on perioperative hemodynamics and behavioral changes in children who underwent skin laser treatment in an academic educational Hospital.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21808844</PMID><DateCreated><Year>2011</Year><Month>8</Month><Day>2</Day></DateCreated><DateCompleted><Year>2012</Year><Month>02</Month><Day>22</Day></DateCompleted><DateRevised><Year>2016</Year><Month>10</Month><Day>20</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1678-2674</ISSN><JournalIssue CitedMedium="Internet"><Volume>26</Volume><Issue>4</Issue><PubDate><Year>2011</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Acta cirurgica brasileira</Title><ISOAbbreviation>Acta Cir Bras</ISOAbbreviation></Journal><ArticleTitle>Perioperative effects of oral midazolam premedication in children undergoing skin laser treatment. A double-blinded randomized placebo-controlled trial.</ArticleTitle><Pagination><MedlinePgn>303-9</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0102-86502011000400010</ELocationID><Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To investigate and compare the efficacy of oral midazolam with two different dosages in orange juice on perioperative hemodynamics and behavioral changes in children who underwent skin laser treatment in an academic educational Hospital.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">Ninety children, candidates for skin laser treatment were randomly assigned to 1 of 3 groups of 30 each: the placebo group received 0.1 ml/kg orange flavored juice, group 2 and 3 receiving 0.5 and 1 mg/kg of injectable midazolam mixed with an equal volume of orange juice, respectively. The main outcome measures included the mask acceptance, patients' behavioral scales and postoperative events.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">There were no significant differences in heart rate, respiratory rate, and systolic blood pressure among the three groups. However, arterial oxygen saturation was significantly reduced in those given 1 mg.kg(-1) midazolam. The median scores of anxiety, separation from parent, preparing an intravenous line, acceptance of the oxygen mask, good sedation, crying reduction and consciousness level were better in midazolam group. Postoperative agitation and re-crying were also more frequent in placebo receivers. Those given 1 mg.kg(-1) midazolam were significantly more optimal for sedation, crying, consciousness, preparing an intravenous line, and postoperative re-crying compared with 0.5 mg.kg(-1) midazolam receivers.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">As a preanaesthetic medication, the 1 mg.kg(-1) dose of orally given midazolam especially in a volume of orange juice and can optimize the children's behavior during skin laser treatment with no serious adverse effects, enhancing their parents' satisfactions about the sedative protocol.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Shoroghi</LastName><ForeName>Mehrdad</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Anaesthesia, Razi Hospital, Tehran University of Medical Sciences, Iran.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Arbabi</LastName><ForeName>Shahriyar</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Farahbakhsh</LastName><ForeName>Farshid</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Sheikhvatan</LastName><ForeName>Mehrdad</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Abbasi</LastName><ForeName>Ali</ForeName><Initials>A</Initials></Author></AuthorList><Language>ENG</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016449">Randomized Controlled Trial</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Brazil</Country><MedlineTA>Acta Cir Bras</MedlineTA><NlmUniqueID>9103983</NlmUniqueID><ISSNLinking>0102-8650</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006993">Hypnotics and Sedatives</NameOfSubstance></Chemical><Chemical><RegistryNumber>R60L0SM5BC</RegistryNumber><NameOfSubstance UI="D008874">Midazolam</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000284" MajorTopicYN="N">Administration, Oral</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001628" MajorTopicYN="N">Beverages</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002675" MajorTopicYN="N">Child, Preschool</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D032084" MajorTopicYN="N">Citrus sinensis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D062109" MajorTopicYN="Y">Dermatologic Surgical Procedures</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004311" MajorTopicYN="N">Double-Blind Method</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006439" MajorTopicYN="N">Hemodynamics</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006993" MajorTopicYN="N">Hypnotics and Sedatives</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D053685" MajorTopicYN="Y">Laser Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008874" MajorTopicYN="N">Midazolam</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D059035" MajorTopicYN="N">Perioperative Period</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011229" MajorTopicYN="Y">Preanesthetic Medication</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2010</Year><Month>12</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2011</Year><Month>3</Month><Day>15</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>8</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>8</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>2</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">21808844</ArticleId><ArticleId IdType="pii">S0102-86502011000400010</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Iran</li></country></list><tree><noCountry><name sortKey="Abbasi, Ali" sort="Abbasi, Ali" uniqKey="Abbasi A" first="Ali" last="Abbasi">Ali Abbasi</name><name sortKey="Arbabi, Shahriyar" sort="Arbabi, Shahriyar" uniqKey="Arbabi S" first="Shahriyar" last="Arbabi">Shahriyar Arbabi</name><name sortKey="Farahbakhsh, Farshid" sort="Farahbakhsh, Farshid" uniqKey="Farahbakhsh F" first="Farshid" last="Farahbakhsh">Farshid Farahbakhsh</name><name sortKey="Sheikhvatan, Mehrdad" sort="Sheikhvatan, Mehrdad" uniqKey="Sheikhvatan M" first="Mehrdad" last="Sheikhvatan">Mehrdad Sheikhvatan</name></noCountry><country name="Iran"><noRegion><name sortKey="Shoroghi, Mehrdad" sort="Shoroghi, Mehrdad" uniqKey="Shoroghi M" first="Mehrdad" last="Shoroghi">Mehrdad Shoroghi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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