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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en"><italic>Trans-acting small interfering RNA4</italic>: key to nutraceutical synthesis in 1 grape development?</title><author><name sortKey="Rock, Christopher D" sort="Rock, Christopher D" uniqKey="Rock C" first="Christopher D." last="Rock">Christopher D. Rock</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23993483</idno><idno type="pmc">3818397</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818397</idno><idno type="RBID">PMC:3818397</idno><idno type="doi">10.1016/j.tplants.2013.07.006</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000D81</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main"><italic>Trans-acting small interfering RNA4</italic>: key to nutraceutical synthesis in 1 grape development?</title><author><name sortKey="Rock, Christopher D" sort="Rock, Christopher D" uniqKey="Rock C" first="Christopher D." last="Rock">Christopher D. Rock</name></author></analytic><series><title level="j">Trends in plant science</title><idno type="ISSN">1360-1385</idno><idno type="eISSN">1878-4372</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The facility and versatility of microRNAs (miRNAs) to evolve and change likely underlies how they have become dominant constituents of eukaryotic genomes. In this opinion article I propose that <italic>trans-acting small interfering RNA gene 4</italic> (<italic>TAS4</italic>) evolution may be important for biosynthesis of polyphenolics, arbuscular symbiosis, and bacterial pathogen etiologies. Expression-based and phylogenetic evidence shows that <italic>TAS4</italic> targets two novel grape (<italic>Vitis vinifera</italic> L.) MYB transcription factors (<italic>VvMYBA6, VvMYBA7</italic>) that spawn phased siRNAs and likely function in nutraceutical bioflavonoid biosynthesis and fruit development. Characterization of the molecular mechanisms of <italic>TAS4</italic> control of plant development and integration into biotic and abiotic stress- and nutrient signaling regulatory networks has applicability to molecular breeding and development of strategies for engineering healthier foods.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9890299</journal-id><journal-id journal-id-type="pubmed-jr-id">20950</journal-id><journal-id journal-id-type="nlm-ta">Trends Plant Sci</journal-id><journal-id journal-id-type="iso-abbrev">Trends Plant Sci.</journal-id><journal-title-group><journal-title>Trends in plant science</journal-title></journal-title-group><issn pub-type="ppub">1360-1385</issn><issn pub-type="epub">1878-4372</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23993483</article-id><article-id pub-id-type="pmc">3818397</article-id><article-id pub-id-type="doi">10.1016/j.tplants.2013.07.006</article-id><article-id pub-id-type="manuscript">NIHMS517579</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title><italic>Trans-acting small interfering RNA4</italic>: key to nutraceutical synthesis in 1 grape development?</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Rock</surname><given-names>Christopher D.</given-names></name><aff id="A1">Department of Biological Sciences, Texas Tech University, Lubbock TX 79409-3131</aff></contrib></contrib-group><author-notes><corresp id="cor1"><italic>Corresponding author:</italic> Rock, C.D. (<email>chris.rock@ttu.edu</email>)</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>23</day><month>9</month><year>2013</year></pub-date><pub-date pub-type="epub"><day>28</day><month>8</month><year>2013</year></pub-date><pub-date pub-type="ppub"><month>11</month><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>11</month><year>2014</year></pub-date><volume>18</volume><issue>11</issue><elocation-id>10.1016/j.tplants.2013.07.006</elocation-id><permissions><copyright-statement>© 2013 Elsevier Ltd. All rights reserved.</copyright-statement><copyright-year>2013</copyright-year></permissions><abstract><p id="P1">The facility and versatility of microRNAs (miRNAs) to evolve and change likely underlies how they have become dominant constituents of eukaryotic genomes. In this opinion article I propose that <italic>trans-acting small interfering RNA gene 4</italic> (<italic>TAS4</italic>) evolution may be important for biosynthesis of polyphenolics, arbuscular symbiosis, and bacterial pathogen etiologies. Expression-based and phylogenetic evidence shows that <italic>TAS4</italic> targets two novel grape (<italic>Vitis vinifera</italic> L.) MYB transcription factors (<italic>VvMYBA6, VvMYBA7</italic>) that spawn phased siRNAs and likely function in nutraceutical bioflavonoid biosynthesis and fruit development. Characterization of the molecular mechanisms of <italic>TAS4</italic> control of plant development and integration into biotic and abiotic stress- and nutrient signaling regulatory networks has applicability to molecular breeding and development of strategies for engineering healthier foods.</p></abstract><funding-group><award-group><funding-source country="United States">National Institute of General Medical Sciences : NIGMS</funding-source><award-id>R21 GM077245 || GM</award-id></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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