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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antioxidant and antimicrobial properties of <italic>Litsea elliptica</italic> Blume and <italic>Litsea resinosa</italic> Blume (Lauraceae)</title><author><name sortKey="Wong, Mui Hung" sort="Wong, Mui Hung" uniqKey="Wong M" first="Mui-Hung" last="Wong">Mui-Hung Wong</name><affiliation><nlm:aff id="aff1"><addr-line>Faculty of Applied Sciences, Universiti Teknologi MARA, Samarahan Campus, Sarawak Branch, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Lim, Li Fang" sort="Lim, Li Fang" uniqKey="Lim L" first="Li-Fang" last="Lim">Li-Fang Lim</name><affiliation><nlm:aff id="aff2"><addr-line>Faculty of Engineering, Computing and Science, Swinburne University of Technology, Sarawak Campus, 93350 Kuching, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ahmad, Fasihuddin Bin" sort="Ahmad, Fasihuddin Bin" uniqKey="Ahmad F" first="Fasihuddin Bin" last="Ahmad">Fasihuddin Bin Ahmad</name><affiliation><nlm:aff id="aff3"><addr-line>Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Assim, Zaini Bin" sort="Assim, Zaini Bin" uniqKey="Assim Z" first="Zaini Bin" last="Assim">Zaini Bin Assim</name><affiliation><nlm:aff id="aff3"><addr-line>Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25182724</idno><idno type="pmc">3985054</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985054</idno><idno type="RBID">PMC:3985054</idno><idno type="doi">10.12980/APJTB.4.2014C1129</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000C49</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antioxidant and antimicrobial properties of <italic>Litsea elliptica</italic> Blume and <italic>Litsea resinosa</italic> Blume (Lauraceae)</title><author><name sortKey="Wong, Mui Hung" sort="Wong, Mui Hung" uniqKey="Wong M" first="Mui-Hung" last="Wong">Mui-Hung Wong</name><affiliation><nlm:aff id="aff1"><addr-line>Faculty of Applied Sciences, Universiti Teknologi MARA, Samarahan Campus, Sarawak Branch, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Lim, Li Fang" sort="Lim, Li Fang" uniqKey="Lim L" first="Li-Fang" last="Lim">Li-Fang Lim</name><affiliation><nlm:aff id="aff2"><addr-line>Faculty of Engineering, Computing and Science, Swinburne University of Technology, Sarawak Campus, 93350 Kuching, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Ahmad, Fasihuddin Bin" sort="Ahmad, Fasihuddin Bin" uniqKey="Ahmad F" first="Fasihuddin Bin" last="Ahmad">Fasihuddin Bin Ahmad</name><affiliation><nlm:aff id="aff3"><addr-line>Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author><author><name sortKey="Assim, Zaini Bin" sort="Assim, Zaini Bin" uniqKey="Assim Z" first="Zaini Bin" last="Assim">Zaini Bin Assim</name><affiliation><nlm:aff id="aff3"><addr-line>Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></nlm:aff></affiliation></author></analytic><series><title level="j">Asian Pacific Journal of Tropical Biomedicine</title><idno type="ISSN">2221-1691</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To investigate antioxidant and antimicrobial activities of two plant species, <italic>Litsea elliptica</italic> (<italic>L. elliptica</italic>) and <italic>Litsea resinosa</italic> (<italic>L. resinosa</italic>).</p></sec><sec><title>Methods</title><p><italic>In vitro</italic> method-2,2-diphenyl-1-picrylhydrazyl radical scavenging assay was conducted for antioxidant activity determination while antimicrobial assay consisted of agar well diffusion assay and mycelial radial growth assay.</p></sec><sec><title>Results</title><p>Methanol extracts of root and stem of <italic>L. elliptica</italic> and <italic>L. resinosa</italic> exhibited the highest antioxidant activity with EC<sub>50</sub> of 23.99, 41.69, 11.22 and 35.48 mg/L respectively. All methanol extracts of <italic>L. resinosa</italic> as well as root extracts from <italic>L. elliptica</italic> showed significant scavenging activity. Hexane extract from stem of <italic>L. resinosa</italic> presented the largest inhibition zone in Gram-negative bacteria <italic>Pseudomonas aeruginosa</italic> and <italic>Escherichia coli</italic> while chloroform extract from inner bark of <italic>L. resinosa</italic> showed major inhibition towards Gram-positive bacteria <italic>Bacillus subtilis</italic>. Essential oils from the root of both species showed significant antifungal activities which are 80.11% and 66.85% respectively.</p></sec><sec><title>Conclusions</title><p>Overall, methanol extracts from root and stem of both species showed antioxidant activity comparable to standard butylated hydroxytoluene. Extracts from <italic>L. resinosa</italic> demonstrated stronger antimicrobial properties compared to that from <italic>L. elliptica</italic>.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Asian Pac J Trop Biomed</journal-id><journal-id journal-id-type="iso-abbrev">Asian Pac J Trop Biomed</journal-id><journal-id journal-id-type="publisher-id">APJTB</journal-id><journal-title-group><journal-title>Asian Pacific Journal of Tropical Biomedicine</journal-title></journal-title-group><issn pub-type="ppub">2221-1691</issn><publisher><publisher-name>Asian Pacific Tropical Medicine Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25182724</article-id><article-id pub-id-type="pmc">3985054</article-id><article-id pub-id-type="publisher-id">apjtb-04-05-386</article-id><article-id pub-id-type="doi">10.12980/APJTB.4.2014C1129</article-id><article-categories><subj-group subj-group-type="heading"><subject>Basic Researches</subject></subj-group></article-categories><title-group><article-title>Antioxidant and antimicrobial properties of <italic>Litsea elliptica</italic> Blume and <italic>Litsea resinosa</italic> Blume (Lauraceae)</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Wong</surname><given-names>Mui-Hung</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Lim</surname><given-names>Li-Fang</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Ahmad</surname><given-names>Fasihuddin bin</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Assim</surname><given-names>Zaini bin</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Faculty of Applied Sciences, Universiti Teknologi MARA, Samarahan Campus, Sarawak Branch, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></aff><aff id="aff2"><label>2</label><addr-line>Faculty of Engineering, Computing and Science, Swinburne University of Technology, Sarawak Campus, 93350 Kuching, Sarawak, Malaysia</addr-line></aff><aff id="aff3"><label>3</label><addr-line>Department of Chemistry, Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, 94300 Kota Samarahan, Sarawak, Malaysia</addr-line></aff><contrib-group><contrib contrib-type="reviewer"><name><surname>Yee</surname><given-names>Ling Teck</given-names><prefix>Associate Professor Dr.</prefix></name></contrib></contrib-group><aff id="aff4">Tel:<phone>+6082-583040</phone> E-mail:<email>tyling@frst.unimas.my</email></aff><author-notes><fn fn-type="other"><p><bold>Comments:</bold> Results of this study are important contributions to the body of knowledge. It has been shown that the methanol extracts of root and stem of both <italic>L. elliptica</italic> and <italic>L. resinosa</italic> showed significant scavenging activity and <italic>L. resinosa</italic> showed strong antibacterial activities compared to <italic>L. eliptica</italic> and less polar extracts such as hexane and dichloromethane extracts showed significant activities as compared to methanol extracts which is polar. Essential oil of both species also showed great potential in inhibiting fungus <italic>F. oxysporum</italic>. Details on Page 391</p></fn><corresp id="cor1">*Corresponding author: Wong Mui Hung, Faculty of Applied Sciences, Universiti Teknologi MARA Sarawak; Samarahan Campus, Jalan Meranek, 94300 Kota Samarahan, Sarawak, Malaysia. Tel: <phone>(+6082) 677439</phone> Fax: <fax>(+6082) 677300</fax> E-mail: <email>Wongmh@sarawak.uitm.edu.my</email>, <email>wongmuihung@gmail.com</email></corresp></author-notes><pub-date pub-type="ppub"><month>5</month><year>2014</year></pub-date><volume>4</volume><issue>5</issue><fpage>386</fpage><lpage>392</lpage><history><date date-type="received"><day>13</day><month>2</month><year>2014</year></date><date date-type="accepted"><day>12</day><month>4</month><year>2014</year></date></history><permissions><copyright-statement>© 2014 by the Asian Pacific Journal of Tropical Biomedicine. All rights reserved.</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><sec><title>Objective</title><p>To investigate antioxidant and antimicrobial activities of two plant species, <italic>Litsea elliptica</italic> (<italic>L. elliptica</italic>) and <italic>Litsea resinosa</italic> (<italic>L. resinosa</italic>).</p></sec><sec><title>Methods</title><p><italic>In vitro</italic> method-2,2-diphenyl-1-picrylhydrazyl radical scavenging assay was conducted for antioxidant activity determination while antimicrobial assay consisted of agar well diffusion assay and mycelial radial growth assay.</p></sec><sec><title>Results</title><p>Methanol extracts of root and stem of <italic>L. elliptica</italic> and <italic>L. resinosa</italic> exhibited the highest antioxidant activity with EC<sub>50</sub> of 23.99, 41.69, 11.22 and 35.48 mg/L respectively. All methanol extracts of <italic>L. resinosa</italic> as well as root extracts from <italic>L. elliptica</italic> showed significant scavenging activity. Hexane extract from stem of <italic>L. resinosa</italic> presented the largest inhibition zone in Gram-negative bacteria <italic>Pseudomonas aeruginosa</italic> and <italic>Escherichia coli</italic> while chloroform extract from inner bark of <italic>L. resinosa</italic> showed major inhibition towards Gram-positive bacteria <italic>Bacillus subtilis</italic>. Essential oils from the root of both species showed significant antifungal activities which are 80.11% and 66.85% respectively.</p></sec><sec><title>Conclusions</title><p>Overall, methanol extracts from root and stem of both species showed antioxidant activity comparable to standard butylated hydroxytoluene. Extracts from <italic>L. resinosa</italic> demonstrated stronger antimicrobial properties compared to that from <italic>L. elliptica</italic>.</p></sec></abstract><kwd-group><kwd><italic>Litsea elliptica</italic></kwd><kwd><italic>Litsea resinosa</italic></kwd><kwd>Antioxidant</kwd><kwd>Antifungal</kwd><kwd>Antibacterial</kwd><kwd>EC<sub>50</sub></kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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