OrangerV1, Pmc, Corpus, bibRecord, 000A69

In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs

Identifieur interne : 000A69 ( Pmc/Corpus ); précédent : 000A68; suivant : 000A70

In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs

Auteurs : Elizabeth A. Mazzio ; Karam F. A. Soliman

Source :

Phytotherapy research : PTR [ 0951-418X ] ; 2009.

RBID : PMC:2650746

Abstract

There is growing use of anticancer complementary and alternative medicines (CAMs) worldwide. The purpose of the current study is to assess a sizeable variety of natural and plant sources of diverse origin, to ascertain prospective research directives for cancer treatment and potential new chemotherapy drug sources. In this study, 374 natural extracts (10 μg/mL-5 mg/mL) were evaluated for dose-dependent tumoricidal effects using immortal neuroblastoma of spontaneous malignant origin. The findings indicate no pattern of tumoricidal effects by diverse plants with similar families/genus under the classes Pinopsida, Equisetopsida, Lycopodiosida, Filicosida, Liliopsida Monocotyledons or Magnoliopsida Dicotyledons. The results indicate that many of the most commonly used CAMs exhibited relatively weak tumoricidal effects including cats claw, astragalus, ginseng, echinacea, mistletoe, milk thistle, slippery elm, cayenne, chamomile, don quai, meadowsweet, motherwort and shepherd's purse. The data demonstrate that the most potent plant extracts were randomly dispersed within the plantae kingdom (LC₅₀ = 31-490 μg/mL) in order of the lowest LC₅₀ Dioscorea villosa (Dioscoreaceae) > Sanguinaria canadensis (Papaveraceae) > Dipsacus asper (Dipsacaceae) > Populus balsamifera (Salicaceae) > Boswellia carteri (Burseraceae) > Cyamopsis psoralioides (Fabaceae) > Rhamnus cathartica (Rhamnaceae) > Larrea tridentate (Zygophyllaceae) > Dichroa febrifuga (Hydrangeaceae) > Batschia canescens (Boraginaceae) > Kochia scoparia (Chenopodiaceae) > Solanum xanthocarpum (Solanaceae) > Opoponax chironium (Umbelliferae) > Caulophyllum thalictroides (Berberidaceae) > Dryopteris crassirhizoma (Dryopteridaceae) > Garcinia cambogia (Clusiaceae) > Vitex agnus-castus (Verbenaceae) > Calamus draco (Arecaceae). These findings show tumoricidal effect by extracts of wild yam root, bloodroot, teasel root, bakuchi seed, dichroa root, kanta kari, garcinia fruit, mace, dragons blood and the biblically referenced herbs: balm of gilead bud, frankincense and myrrh gum.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650746

DOI: 10.1002/ptr.2636
PubMed: 18844256
PubMed Central: 2650746

Links to Exploration step

PMC:2650746

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en"><italic>In Vitro</italic>
 Screening for the Tumoricidal Properties of International Medicinal Herbs</title>
<author><name sortKey="Mazzio, Elizabeth A" sort="Mazzio, Elizabeth A" uniqKey="Mazzio E" first="Elizabeth A." last="Mazzio">Elizabeth A. Mazzio</name>
</author>
<author><name sortKey="Soliman, Karam F A" sort="Soliman, Karam F A" uniqKey="Soliman K" first="Karam F. A." last="Soliman">Karam F. A. Soliman</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">18844256</idno>
<idno type="pmc">2650746</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2650746</idno>
<idno type="RBID">PMC:2650746</idno>
<idno type="doi">10.1002/ptr.2636</idno>
<date when="2009">2009</date>
<idno type="wicri:Area/Pmc/Corpus">000A69</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main"><italic>In Vitro</italic>
 Screening for the Tumoricidal Properties of International Medicinal Herbs</title>
<author><name sortKey="Mazzio, Elizabeth A" sort="Mazzio, Elizabeth A" uniqKey="Mazzio E" first="Elizabeth A." last="Mazzio">Elizabeth A. Mazzio</name>
</author>
<author><name sortKey="Soliman, Karam F A" sort="Soliman, Karam F A" uniqKey="Soliman K" first="Karam F. A." last="Soliman">Karam F. A. Soliman</name>
</author>
</analytic>
<series><title level="j">Phytotherapy research : PTR</title>
<idno type="ISSN">0951-418X</idno>
<idno type="eISSN">1099-1573</idno>
<imprint><date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">There is growing use of anticancer complementary and alternative medicines (CAMs) worldwide. The purpose of the current study is to assess a sizeable variety of natural and plant sources of diverse origin, to ascertain prospective research directives for cancer treatment and potential new chemotherapy drug sources. In this study, 374 natural extracts (10 μg/mL-5 mg/mL) were evaluated for dose-dependent tumoricidal effects using immortal neuroblastoma of spontaneous malignant origin. The findings indicate no pattern of tumoricidal effects by diverse plants with similar families/genus under the classes Pinopsida, Equisetopsida, Lycopodiosida, Filicosida, Liliopsida Monocotyledons or Magnoliopsida Dicotyledons. The results indicate that many of the most commonly used CAMs exhibited relatively weak tumoricidal effects including cats claw, astragalus, ginseng, echinacea, mistletoe, milk thistle, slippery elm, cayenne, chamomile, don quai, meadowsweet, motherwort and shepherd's purse. The data demonstrate that the most potent plant extracts were randomly dispersed within the plantae kingdom (LC<sub>50</sub>
 = 31-490 μg/mL) in order of the lowest LC<sub>50</sub>
 <italic>Dioscorea villosa</italic>
 (Dioscoreaceae) > <italic>Sanguinaria canadensis</italic>
 (Papaveraceae) > <italic>Dipsacus asper</italic>
 (Dipsacaceae) > <italic>Populus balsamifera</italic>
 (Salicaceae) > <italic>Boswellia carteri</italic>
 (Burseraceae) > <italic>Cyamopsis psoralioides</italic>
 (Fabaceae) > <italic>Rhamnus cathartica</italic>
 (Rhamnaceae) > <italic>Larrea tridentate</italic>
 (Zygophyllaceae) > <italic>Dichroa febrifuga</italic>
 (Hydrangeaceae) > <italic>Batschia canescens</italic>
 (Boraginaceae) > <italic>Kochia scoparia</italic>
 (Chenopodiaceae) > <italic>Solanum xanthocarpum</italic>
 (Solanaceae) > <italic>Opoponax</italic>
 chironium (Umbelliferae) > <italic>Caulophyllum thalictroides</italic>
 (Berberidaceae) > <italic>Dryopteris crassirhizoma</italic>
 (Dryopteridaceae) > <italic>Garcinia cambogia</italic>
 (Clusiaceae) > <italic>Vitex agnus-castus</italic>
 (Verbenaceae) > <italic>Calamus draco</italic>
 (Arecaceae). These findings show tumoricidal effect by extracts of wild yam root, bloodroot, teasel root, bakuchi seed, dichroa root, kanta kari, garcinia fruit, mace, dragons blood and the biblically referenced herbs: balm of gilead bud, frankincense and myrrh gum.</p>
</div>
</front>
</TEI>
<pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
  <pmc-dir>properties manuscript</pmc-dir>
  <front><journal-meta><journal-id journal-id-type="nlm-journal-id">8904486</journal-id>
<journal-id journal-id-type="pubmed-jr-id">21098</journal-id>
<journal-id journal-id-type="nlm-ta">Phytother Res</journal-id>
<journal-title>Phytotherapy research : PTR</journal-title>
<issn pub-type="ppub">0951-418X</issn>
<issn pub-type="epub">1099-1573</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">18844256</article-id>
<article-id pub-id-type="pmc">2650746</article-id>
<article-id pub-id-type="doi">10.1002/ptr.2636</article-id>
<article-id pub-id-type="manuscript">NIHMS86121</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title><italic>In Vitro</italic>
 Screening for the Tumoricidal Properties of International Medicinal Herbs</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Mazzio</surname>
<given-names>Elizabeth A.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Soliman</surname>
<given-names>Karam F. A.</given-names>
</name>
<xref ref-type="corresp" rid="CR1">*</xref>
</contrib>
<aff id="A1">College of Pharmacy and Pharmaceutical Sciences, Florida A & M University, Tallahassee, Florida 32307, USA</aff>
</contrib-group>
<author-notes><corresp id="CR1"><label>*</label>
Correspondence to: Dr Karam F. A. Soliman, College of Pharmacy and Pharmaceutical Sciences, Florida A & M University, Tallahassee, FL 32307, USA. E-mail: <email>karam.soliman@famu.edu</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>7</day>
<month>1</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="ppub"><month>3</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>3</day>
<month>3</month>
<year>2009</year>
</pub-date>
<volume>23</volume>
<issue>3</issue>
<fpage>385</fpage>
<lpage>398</lpage>
<permissions><copyright-statement>Copyright © 2008 John Wiley & Sons, Ltd.</copyright-statement>
<copyright-year>2008</copyright-year>
</permissions>
<abstract><p id="P1">There is growing use of anticancer complementary and alternative medicines (CAMs) worldwide. The purpose of the current study is to assess a sizeable variety of natural and plant sources of diverse origin, to ascertain prospective research directives for cancer treatment and potential new chemotherapy drug sources. In this study, 374 natural extracts (10 μg/mL-5 mg/mL) were evaluated for dose-dependent tumoricidal effects using immortal neuroblastoma of spontaneous malignant origin. The findings indicate no pattern of tumoricidal effects by diverse plants with similar families/genus under the classes Pinopsida, Equisetopsida, Lycopodiosida, Filicosida, Liliopsida Monocotyledons or Magnoliopsida Dicotyledons. The results indicate that many of the most commonly used CAMs exhibited relatively weak tumoricidal effects including cats claw, astragalus, ginseng, echinacea, mistletoe, milk thistle, slippery elm, cayenne, chamomile, don quai, meadowsweet, motherwort and shepherd's purse. The data demonstrate that the most potent plant extracts were randomly dispersed within the plantae kingdom (LC<sub>50</sub>
 = 31-490 μg/mL) in order of the lowest LC<sub>50</sub>
 <italic>Dioscorea villosa</italic>
 (Dioscoreaceae) > <italic>Sanguinaria canadensis</italic>
 (Papaveraceae) > <italic>Dipsacus asper</italic>
 (Dipsacaceae) > <italic>Populus balsamifera</italic>
 (Salicaceae) > <italic>Boswellia carteri</italic>
 (Burseraceae) > <italic>Cyamopsis psoralioides</italic>
 (Fabaceae) > <italic>Rhamnus cathartica</italic>
 (Rhamnaceae) > <italic>Larrea tridentate</italic>
 (Zygophyllaceae) > <italic>Dichroa febrifuga</italic>
 (Hydrangeaceae) > <italic>Batschia canescens</italic>
 (Boraginaceae) > <italic>Kochia scoparia</italic>
 (Chenopodiaceae) > <italic>Solanum xanthocarpum</italic>
 (Solanaceae) > <italic>Opoponax</italic>
 chironium (Umbelliferae) > <italic>Caulophyllum thalictroides</italic>
 (Berberidaceae) > <italic>Dryopteris crassirhizoma</italic>
 (Dryopteridaceae) > <italic>Garcinia cambogia</italic>
 (Clusiaceae) > <italic>Vitex agnus-castus</italic>
 (Verbenaceae) > <italic>Calamus draco</italic>
 (Arecaceae). These findings show tumoricidal effect by extracts of wild yam root, bloodroot, teasel root, bakuchi seed, dichroa root, kanta kari, garcinia fruit, mace, dragons blood and the biblically referenced herbs: balm of gilead bud, frankincense and myrrh gum.</p>
</abstract>
<kwd-group><kwd>herbs</kwd>
<kwd>screening</kwd>
<kwd>cancer</kwd>
<kwd>wild yam</kwd>
<kwd>frankincense</kwd>
<kwd>teasel</kwd>
<kwd>myrrh</kwd>
</kwd-group>
<contract-num rid="RR1">G12 RR003020-255367
				||RR</contract-num>
<contract-num rid="RR1">G12 RR003020-140002
				||RR</contract-num>
<contract-sponsor id="RR1">National Center for Research Resources : NCRR</contract-sponsor>
</article-meta>
</front>
</pmc>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Pmc/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A69 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000A69 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Bois
   |area=    OrangerV1
   |flux=    Pmc
   |étape=   Corpus
   |type=    RBID
   |clé=     PMC:2650746
   |texte=   In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i   -Sk "pubmed:18844256" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a OrangerV1

This area was generated with Dilib version V0.6.25.
Data generation: Sat Dec 3 17:11:04 2016. Site generation: Wed Mar 6 18:18:32 2024

	Serveur d'exploration sur l'oranger
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur l'oranger

In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs

In Vitro Screening for the Tumoricidal Properties of International Medicinal Herbs

Source :

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki