Loss of Body Weight and Fat and Improved Lipid Profiles in Obese Rats Fed Apple Pomace or Apple Juice Concentrate
Identifieur interne : 000A37 ( Pmc/Checkpoint ); précédent : 000A36; suivant : 000A38Loss of Body Weight and Fat and Improved Lipid Profiles in Obese Rats Fed Apple Pomace or Apple Juice Concentrate
Auteurs : Kyung-Dong Cho ; Chan-Kyu Han ; Bog-Hieu LeeSource :
- Journal of Medicinal Food [ 1096-620X ] ; 2013.
Abstract
The purpose of this study was to investigate the influence of apple pomace (AP) and apple juice concentrate (AC) supplementation on body weight and fat loss as well as lipid metabolism in obese rats fed a high-fat diet. Diet-induced obese rats were assigned to three groups (
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DOI: 10.1089/jmf.2013.2784
PubMed: 23909905
PubMed Central: 3778949
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Loss of Body Weight and Fat and Improved Lipid Profiles in Obese Rats Fed Apple Pomace or Apple Juice Concentrate</title><author><name sortKey="Cho, Kyung Dong" sort="Cho, Kyung Dong" uniqKey="Cho K" first="Kyung-Dong" last="Cho">Kyung-Dong Cho</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Han, Chan Kyu" sort="Han, Chan Kyu" uniqKey="Han C" first="Chan-Kyu" last="Han">Chan-Kyu Han</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Lee, Bog Hieu" sort="Lee, Bog Hieu" uniqKey="Lee B" first="Bog-Hieu" last="Lee">Bog-Hieu Lee</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23909905</idno><idno type="pmc">3778949</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778949</idno><idno type="RBID">PMC:3778949</idno><idno type="doi">10.1089/jmf.2013.2784</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000C67</idno><idno type="wicri:Area/Pmc/Curation">000C66</idno><idno type="wicri:Area/Pmc/Checkpoint">000A37</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Loss of Body Weight and Fat and Improved Lipid Profiles in Obese Rats Fed Apple Pomace or Apple Juice Concentrate</title><author><name sortKey="Cho, Kyung Dong" sort="Cho, Kyung Dong" uniqKey="Cho K" first="Kyung-Dong" last="Cho">Kyung-Dong Cho</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Han, Chan Kyu" sort="Han, Chan Kyu" uniqKey="Han C" first="Chan-Kyu" last="Han">Chan-Kyu Han</name><affiliation><nlm:aff id="aff2"></nlm:aff></affiliation></author><author><name sortKey="Lee, Bog Hieu" sort="Lee, Bog Hieu" uniqKey="Lee B" first="Bog-Hieu" last="Lee">Bog-Hieu Lee</name><affiliation><nlm:aff id="aff3"></nlm:aff></affiliation></author></analytic><series><title level="j">Journal of Medicinal Food</title><idno type="ISSN">1096-620X</idno><idno type="eISSN">1557-7600</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Abstract</title><p>The purpose of this study was to investigate the influence of apple pomace (AP) and apple juice concentrate (AC) supplementation on body weight and fat loss as well as lipid metabolism in obese rats fed a high-fat diet. Diet-induced obese rats were assigned to three groups (<italic>n</italic>=8 for each group): high fat diet (HFD) control, HFD containing 10% (w/w) AP, and HFD containing 10% (w/w) AC. There was also a normal diet group (<italic>n</italic>=8). After 5 weeks, body weight gain, adipose tissue weight, serum and hepatic lipid profiles, liver morphology, and adipocyte size were measured. Body weight gain, white adipose tissue (WAT) weight, serum total cholesterol, low-density lipoprotein cholesterol and triglyceride concentrations, epididymal adipocyte size, and lesion scores were significantly lower and serum high-density lipoprotein cholesterol concentration and brown adipose tissue weights were significantly higher in the AP and AC groups compared with the HFD group. In addition, atherogenic indices in the AP and AC groups were significantly lower than in the HFD group. These results indicate that supplementing apple products such as AP and AC may help suppress body weight and WAT gain, as well as improve lipid profiles in diet-induced obese rats.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">J Med Food</journal-id><journal-id journal-id-type="iso-abbrev">J Med Food</journal-id><journal-id journal-id-type="publisher-id">jmf</journal-id><journal-title-group><journal-title>Journal of Medicinal Food</journal-title></journal-title-group><issn pub-type="ppub">1096-620X</issn><issn pub-type="epub">1557-7600</issn><publisher><publisher-name>Mary Ann Liebert, Inc.</publisher-name><publisher-loc>140 Huguenot Street, 3rd FloorNew Rochelle, NY 10801USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23909905</article-id><article-id pub-id-type="pmc">3778949</article-id><article-id pub-id-type="publisher-id">10.1089/jmf.2013.2784</article-id><article-id pub-id-type="doi">10.1089/jmf.2013.2784</article-id><article-categories><subj-group subj-group-type="heading"><subject>Full Communications</subject></subj-group></article-categories><title-group><article-title>Loss of Body Weight and Fat and Improved Lipid Profiles in Obese Rats Fed Apple Pomace or Apple Juice Concentrate</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Cho</surname><given-names>Kyung-Dong</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Han</surname><given-names>Chan-Kyu</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Lee</surname><given-names>Bog-Hieu</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><aff id="aff1"><label><sup>1</sup></label>Food Policy & Technology Research Institute,<institution>Food One Tech Co., Ltd.</institution>, Seoul, Korea.</aff><aff id="aff2"><label><sup>2</sup></label><institution>Korea Food Research Institute</institution>, Seongnam City, Gyeonggi, Korea.</aff><aff id="aff3"><label><sup>3</sup></label>Department of Food & Nutrition, School of Food Science and Technology,<institution>Chung-Ang University</institution>, Anseong, Korea.</aff></contrib-group><author-notes><corresp><italic>Address correspondence to: Bog-Hieu Lee, PhD, Department of Food & Nutrition, School of Food Science and Technology, Chung-Ang University, Anseong, Gyeonggi 456-756, Korea. E-mail:</italic><email xlink:href="mailto:lbheelb@cau.ac.kr">lbheelb@cau.ac.kr</email></corresp></author-notes><pub-date pub-type="ppub"><month>9</month><year>2013</year><pmc-comment>string-date: September 2013</pmc-comment>
</pub-date><volume>16</volume><issue>9</issue><fpage>823</fpage><lpage>830</lpage><history><date date-type="received"><day>29</day><month>1</month><year>2013</year><pmc-comment>string-date: Manuscript received 29 January 2013</pmc-comment>
</date><date date-type="accepted"><day>24</day><month>5</month><year>2013</year><pmc-comment>string-date: Revision accepted 24 May 2013</pmc-comment>
</date></history><permissions><copyright-statement>Copyright 2013, Mary Ann Liebert, Inc. and Korean Society of Food Science and Nutrition</copyright-statement><copyright-year>2013</copyright-year></permissions><self-uri xlink:type="simple" xlink:href="jmf.2013.2784.pdf"></self-uri><abstract><title>Abstract</title><p>The purpose of this study was to investigate the influence of apple pomace (AP) and apple juice concentrate (AC) supplementation on body weight and fat loss as well as lipid metabolism in obese rats fed a high-fat diet. Diet-induced obese rats were assigned to three groups (<italic>n</italic>=8 for each group): high fat diet (HFD) control, HFD containing 10% (w/w) AP, and HFD containing 10% (w/w) AC. There was also a normal diet group (<italic>n</italic>=8). After 5 weeks, body weight gain, adipose tissue weight, serum and hepatic lipid profiles, liver morphology, and adipocyte size were measured. Body weight gain, white adipose tissue (WAT) weight, serum total cholesterol, low-density lipoprotein cholesterol and triglyceride concentrations, epididymal adipocyte size, and lesion scores were significantly lower and serum high-density lipoprotein cholesterol concentration and brown adipose tissue weights were significantly higher in the AP and AC groups compared with the HFD group. In addition, atherogenic indices in the AP and AC groups were significantly lower than in the HFD group. These results indicate that supplementing apple products such as AP and AC may help suppress body weight and WAT gain, as well as improve lipid profiles in diet-induced obese rats.</p></abstract><kwd-group kwd-group-type="author"><title>Key Words</title><kwd><italic>apple products</italic></kwd><kwd><italic>body fat loss</italic></kwd><kwd><italic>diet-induced obese rats</italic></kwd><kwd><italic>lipid profile</italic></kwd></kwd-group><counts><fig-count count="4"></fig-count><table-count count="5"></table-count><ref-count count="50"></ref-count><page-count count="8"></page-count></counts></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Cho, Kyung Dong" sort="Cho, Kyung Dong" uniqKey="Cho K" first="Kyung-Dong" last="Cho">Kyung-Dong Cho</name><name sortKey="Han, Chan Kyu" sort="Han, Chan Kyu" uniqKey="Han C" first="Chan-Kyu" last="Han">Chan-Kyu Han</name><name sortKey="Lee, Bog Hieu" sort="Lee, Bog Hieu" uniqKey="Lee B" first="Bog-Hieu" last="Lee">Bog-Hieu Lee</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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