OrangerV1, PascalFrancis, Corpus, bibRecord, 000859

In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India

Identifieur interne : 000859 ( PascalFrancis/Corpus ); précédent : 000858; suivant : 000860

In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India

Auteurs : G. Praveen Bhat ; Namita Surolia

Source :

The American journal of tropical medicine and hygiene [ 0002-9637 ] ; 2001.

RBID : Pascal:02-0081525

Descripteurs français

Pascal (Inist)
- Origine végétale, In vitro, Plasmodium falciparum, Activité biologique, Antipaludique, Antiparasitaire, Extrait, Médecine traditionnelle, Inde.

English descriptors

KwdEn :
- Antimalarial, Biological activity, Extract, Folk medicine, In vitro, India, Parasiticid, Plant origin, Plasmodium falciparum.

Abstract

In an attempt to search for new antimalarial drugs, we studied plants used by traditional healers of southwest India to treat malaria. Aqueous and organic solvent extracts obtained from specific parts of the plants Swertia chirata, Carica papaya, and Citrus sinensis were tested on malaria strain Plasmodium falciparum FCK 2 in vitro. The temperatures of extraction were the same as that used by the traditional healers in their plant preparations. Visual evaluation of the antimalarial activity of the plant extracts on thin blood smears was followed by quantification of the activity by use of [³⁵S]-methionine incorporation into parasite proteins to determine the value that inhibits 50% (IC₅₀). Among the 3 plants tested, 2 had significant inhibitory effect on P. falciparum in vitro.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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A02	`01`			`@0 AJTHAB`
A03		`1`		`@0 Am. j. trop. med. hyg.`
A05				`@2 65`
A06				`@2 4`
A08	`01`	`1`	`ENG`	`@1 In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India`
A11	`01`	`1`		`@1 PRAVEEN BHAT (G.)`
A11	`02`	`1`		`@1 SUROLIA (Namita)`
A14	`01`			`@1 Molecular Biology and Genetics Unit, Jawaharlal Nehru Center for Advanced Scientific Research @2 Bangalore 560064 Karnataka State @3 IND @Z 1 aut. @Z 2 aut.`
A20				`@1 304-308`
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A23	`01`			`@0 ENG`
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A44				`@0 0000 @1 © 2002 INIST-CNRS. All rights reserved.`
A45				`@0 16 ref.`
A47	`01`	`1`		`@0 02-0081525`
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A61				`@0 A`
A64	`01`	`1`		`@0 The American journal of tropical medicine and hygiene`
A66	`01`			`@0 USA`
C01	`01`		`ENG`	@0 In an attempt to search for new antimalarial drugs, we studied plants used by traditional healers of southwest India to treat malaria. Aqueous and organic solvent extracts obtained from specific parts of the plants Swertia chirata, Carica papaya, and Citrus sinensis were tested on malaria strain Plasmodium falciparum FCK 2 in vitro. The temperatures of extraction were the same as that used by the traditional healers in their plant preparations. Visual evaluation of the antimalarial activity of the plant extracts on thin blood smears was followed by quantification of the activity by use of [³⁵S]-methionine incorporation into parasite proteins to determine the value that inhibits 50% (IC₅₀). Among the 3 plants tested, 2 had significant inhibitory effect on P. falciparum in vitro.
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C03	`01`	`X`	`ENG`	`@0 Plant origin @5 01`
C03	`01`	`X`	`SPA`	`@0 Origen vegetal @5 01`
C03	`02`	`X`	`FRE`	`@0 In vitro @5 02`
C03	`02`	`X`	`ENG`	`@0 In vitro @5 02`
C03	`02`	`X`	`SPA`	`@0 In vitro @5 02`
C03	`03`	`X`	`FRE`	`@0 Plasmodium falciparum @2 NS @5 03`
C03	`03`	`X`	`ENG`	`@0 Plasmodium falciparum @2 NS @5 03`
C03	`03`	`X`	`SPA`	`@0 Plasmodium falciparum @2 NS @5 03`
C03	`04`	`X`	`FRE`	`@0 Activité biologique @5 08`
C03	`04`	`X`	`ENG`	`@0 Biological activity @5 08`
C03	`04`	`X`	`SPA`	`@0 Actividad biológica @5 08`
C03	`05`	`X`	`FRE`	`@0 Antipaludique @5 09`
C03	`05`	`X`	`ENG`	`@0 Antimalarial @5 09`
C03	`05`	`X`	`SPA`	`@0 Antipalúdico @5 09`
C03	`06`	`X`	`FRE`	`@0 Antiparasitaire @5 11`
C03	`06`	`X`	`ENG`	`@0 Parasiticid @5 11`
C03	`06`	`X`	`SPA`	`@0 Antiparasitario @5 11`
C03	`07`	`X`	`FRE`	`@0 Extrait @5 12`
C03	`07`	`X`	`ENG`	`@0 Extract @5 12`
C03	`07`	`X`	`SPA`	`@0 Extracto @5 12`
C03	`08`	`X`	`FRE`	`@0 Médecine traditionnelle @5 17`
C03	`08`	`X`	`ENG`	`@0 Folk medicine @5 17`
C03	`08`	`X`	`SPA`	`@0 Medicina tradicional @5 17`
C03	`09`	`X`	`FRE`	`@0 Inde @2 NG @5 18`
C03	`09`	`X`	`ENG`	`@0 India @2 NG @5 18`
C03	`09`	`X`	`SPA`	`@0 India @2 NG @5 18`
C07	`01`	`X`	`FRE`	`@0 Apicomplexa @2 NS`
C07	`01`	`X`	`ENG`	`@0 Apicomplexa @2 NS`
C07	`01`	`X`	`SPA`	`@0 Apicomplexa @2 NS`
C07	`02`	`X`	`FRE`	`@0 Protozoa @2 NS`
C07	`02`	`X`	`ENG`	`@0 Protozoa @2 NS`
C07	`02`	`X`	`SPA`	`@0 Protozoa @2 NS`
C07	`03`	`X`	`FRE`	`@0 Asie @2 NG`
C07	`03`	`X`	`ENG`	`@0 Asia @2 NG`
C07	`03`	`X`	`SPA`	`@0 Asia @2 NG`
N21				`@1 042`

Format Inist (serveur)

NO :	PASCAL 02-0081525 INIST
ET :	In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India
AU :	PRAVEEN BHAT (G.); SUROLIA (Namita)
AF :	Molecular Biology and Genetics Unit, Jawaharlal Nehru Center for Advanced Scientific Research/Bangalore 560064 Karnataka State/Inde (1 aut., 2 aut.)
DT :	Publication en série; Niveau analytique
SO :	The American journal of tropical medicine and hygiene; ISSN 0002-9637; Coden AJTHAB; Etats-Unis; Da. 2001; Vol. 65; No. 4; Pp. 304-308; Bibl. 16 ref.
LA :	Anglais
EA :	In an attempt to search for new antimalarial drugs, we studied plants used by traditional healers of southwest India to treat malaria. Aqueous and organic solvent extracts obtained from specific parts of the plants Swertia chirata, Carica papaya, and Citrus sinensis were tested on malaria strain Plasmodium falciparum FCK 2 in vitro. The temperatures of extraction were the same as that used by the traditional healers in their plant preparations. Visual evaluation of the antimalarial activity of the plant extracts on thin blood smears was followed by quantification of the activity by use of [³⁵S]-methionine incorporation into parasite proteins to determine the value that inhibits 50% (IC₅₀). Among the 3 plants tested, 2 had significant inhibitory effect on P. falciparum in vitro.
CC :	002B02A04; 235
FD :	Origine végétale; In vitro; Plasmodium falciparum; Activité biologique; Antipaludique; Antiparasitaire; Extrait; Médecine traditionnelle; Inde
FG :	Apicomplexa; Protozoa; Asie
ED :	Plant origin; In vitro; Plasmodium falciparum; Biological activity; Antimalarial; Parasiticid; Extract; Folk medicine; India
EG :	Apicomplexa; Protozoa; Asia
SD :	Origen vegetal; In vitro; Plasmodium falciparum; Actividad biológica; Antipalúdico; Antiparasitario; Extracto; Medicina tradicional; India
LO :	INIST-6817.354000099932220090
ID :	02-0081525

Links to Exploration step

Pascal:02-0081525

Le document en format XML

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<front><div type="abstract" xml:lang="en">In an attempt to search for new antimalarial drugs, we studied plants used by traditional healers of southwest India to treat malaria. Aqueous and organic solvent extracts obtained from specific parts of the plants Swertia chirata, Carica papaya, and Citrus sinensis were tested on malaria strain Plasmodium falciparum FCK 2 in vitro. The temperatures of extraction were the same as that used by the traditional healers in their plant preparations. Visual evaluation of the antimalarial activity of the plant extracts on thin blood smears was followed by quantification of the activity by use of [<sup>35</sup>
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<ET>In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India</ET>
<AU>PRAVEEN BHAT (G.); SUROLIA (Namita)</AU>
<AF>Molecular Biology and Genetics Unit, Jawaharlal Nehru Center for Advanced Scientific Research/Bangalore 560064 Karnataka State/Inde (1 aut., 2 aut.)</AF>
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<EA>In an attempt to search for new antimalarial drugs, we studied plants used by traditional healers of southwest India to treat malaria. Aqueous and organic solvent extracts obtained from specific parts of the plants Swertia chirata, Carica papaya, and Citrus sinensis were tested on malaria strain Plasmodium falciparum FCK 2 in vitro. The temperatures of extraction were the same as that used by the traditional healers in their plant preparations. Visual evaluation of the antimalarial activity of the plant extracts on thin blood smears was followed by quantification of the activity by use of [<sup>35</sup>
S]-methionine incorporation into parasite proteins to determine the value that inhibits 50% (IC<sub>50</sub>
). Among the 3 plants tested, 2 had significant inhibitory effect on P. falciparum in vitro.</EA>
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In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India

In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India

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