Structural and Physiological Analyses of the Alkanesulphonate-Binding Protein (SsuA) of the Citrus Pathogen Xanthomonas citri
Identifieur interne : 000D19 ( Main/Exploration ); précédent : 000D18; suivant : 000D20Structural and Physiological Analyses of the Alkanesulphonate-Binding Protein (SsuA) of the Citrus Pathogen Xanthomonas citri
Auteurs : Fabiano T Foli De Araújo [Brésil] ; Victor M. Bolanos-Garcia [Royaume-Uni] ; Cristiane T. Pereira [Brésil] ; Mario Sanches [Canada] ; Elisa E. Oshiro [Brésil] ; Rita C. C. Ferreira [Brésil] ; Dimitri Y. Chigardze [Royaume-Uni] ; João Alexandre Gonçalves Barbosa [Brésil] ; Luís Carlos De Souza Ferreira [Brésil] ; Celso E. Benedetti [Brésil] ; Tom L. Blundell [Royaume-Uni] ; Andrea Balan [Brésil]Source :
- PLoS ONE [ 1932-6203 ] ; 2013.
English descriptors
- KwdEn :
- Alkanesulfonates (chemistry), Alkanesulfonates (metabolism), Amino Acid Sequence, Bacterial Proteins (chemistry), Bacterial Proteins (genetics), Bacterial Proteins (physiology), Binding Sites, Carrier Proteins (chemistry), Carrier Proteins (genetics), Carrier Proteins (physiology), Citrus sinensis (growth & development), Citrus sinensis (metabolism), Citrus sinensis (microbiology), Models, Molecular, Molecular Sequence Data, Plant Diseases (microbiology), Polysaccharides, Bacterial (metabolism), Sequence Alignment, Virulence, X-Ray Diffraction, Xanthomonas (genetics), Xanthomonas (metabolism), Xanthomonas (pathogenicity).
- MESH :
- chemical , chemistry : Alkanesulfonates, Bacterial Proteins, Carrier Proteins.
- chemical , genetics : Bacterial Proteins, Carrier Proteins.
- chemical , metabolism : Alkanesulfonates, Polysaccharides, Bacterial.
- chemical , physiology : Bacterial Proteins, Carrier Proteins.
- genetics : Xanthomonas.
- growth & development : Citrus sinensis.
- metabolism : Citrus sinensis, Xanthomonas.
- microbiology : Citrus sinensis, Plant Diseases.
- pathogenicity : Xanthomonas.
- Amino Acid Sequence, Binding Sites, Models, Molecular, Molecular Sequence Data, Sequence Alignment, Virulence, X-Ray Diffraction.
Abstract
The uptake of sulphur-containing compounds plays a pivotal role in the physiology of bacteria that live in aerobic soils where organosulfur compounds such as sulphonates and sulphate esters represent more than 95% of the available sulphur. Until now, no information has been available on the uptake of sulphonates by bacterial plant pathogens, particularly those of the
A single operon-like gene cluster (
The present study unravels unique structural and functional features of the
Url:
DOI: 10.1371/journal.pone.0080083
PubMed: 24282519
PubMed Central: 3839906
Affiliations:
- Brésil, Canada, Royaume-Uni
- Angleterre, Angleterre de l'Est, État de São Paulo
- Cambridge, São Paulo
- Université de Cambridge, Université de São Paulo
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001180
- to stream Pmc, to step Curation: 001179
- to stream Pmc, to step Checkpoint: 000979
- to stream PubMed, to step Corpus: 000411
- to stream PubMed, to step Curation: 000411
- to stream PubMed, to step Checkpoint: 000411
- to stream Ncbi, to step Merge: 001517
- to stream Ncbi, to step Curation: 001517
- to stream Ncbi, to step Checkpoint: 001517
- to stream Main, to step Merge: 000D23
- to stream Main, to step Curation: 000D19
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Structural and Physiological Analyses of the Alkanesulphonate-Binding Protein (SsuA) of the Citrus Pathogen <italic>Xanthomonas citri</italic>
</title>
<author><name sortKey="T Foli De Araujo, Fabiano" sort="T Foli De Araujo, Fabiano" uniqKey="T Foli De Araujo F" first="Fabiano" last="T Foli De Araújo">Fabiano T Foli De Araújo</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Bolanos Garcia, Victor M" sort="Bolanos Garcia, Victor M" uniqKey="Bolanos Garcia V" first="Victor M." last="Bolanos-Garcia">Victor M. Bolanos-Garcia</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pereira, Cristiane T" sort="Pereira, Cristiane T" uniqKey="Pereira C" first="Cristiane T." last="Pereira">Cristiane T. Pereira</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanches, Mario" sort="Sanches, Mario" uniqKey="Sanches M" first="Mario" last="Sanches">Mario Sanches</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Monte Sinai Hospital, Toronto, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Monte Sinai Hospital, Toronto, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oshiro, Elisa E" sort="Oshiro, Elisa E" uniqKey="Oshiro E" first="Elisa E." last="Oshiro">Elisa E. Oshiro</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Ferreira, Rita C C" sort="Ferreira, Rita C C" uniqKey="Ferreira R" first="Rita C. C." last="Ferreira">Rita C. C. Ferreira</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Chigardze, Dimitri Y" sort="Chigardze, Dimitri Y" uniqKey="Chigardze D" first="Dimitri Y." last="Chigardze">Dimitri Y. Chigardze</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barbosa, Joao Alexandre Goncalves" sort="Barbosa, Joao Alexandre Goncalves" uniqKey="Barbosa J" first="João Alexandre Gonçalves" last="Barbosa">João Alexandre Gonçalves Barbosa</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><addr-line>Departamento de Genética, Universidade Católica de Brasília, Brasilia, Districto Federal, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Genética, Universidade Católica de Brasília, Brasilia, Districto Federal</wicri:regionArea>
<wicri:noRegion>Districto Federal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Souza Ferreira, Luis Carlos" sort="De Souza Ferreira, Luis Carlos" uniqKey="De Souza Ferreira L" first="Luís Carlos" last="De Souza Ferreira">Luís Carlos De Souza Ferreira</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Benedetti, Celso E" sort="Benedetti, Celso E" uniqKey="Benedetti C" first="Celso E." last="Benedetti">Celso E. Benedetti</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blundell, Tom L" sort="Blundell, Tom L" uniqKey="Blundell T" first="Tom L." last="Blundell">Tom L. Blundell</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Balan, Andrea" sort="Balan, Andrea" uniqKey="Balan A" first="Andrea" last="Balan">Andrea Balan</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">24282519</idno>
<idno type="pmc">3839906</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839906</idno>
<idno type="RBID">PMC:3839906</idno>
<idno type="doi">10.1371/journal.pone.0080083</idno>
<date when="2013">2013</date>
<idno type="wicri:Area/Pmc/Corpus">001180</idno>
<idno type="wicri:Area/Pmc/Curation">001179</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000979</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="wicri:Area/PubMed/Corpus">000411</idno>
<idno type="wicri:Area/PubMed/Curation">000411</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000411</idno>
<idno type="wicri:Area/Ncbi/Merge">001517</idno>
<idno type="wicri:Area/Ncbi/Curation">001517</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001517</idno>
<idno type="wicri:Area/Main/Merge">000D23</idno>
<idno type="wicri:Area/Main/Curation">000D19</idno>
<idno type="wicri:Area/Main/Exploration">000D19</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Structural and Physiological Analyses of the Alkanesulphonate-Binding Protein (SsuA) of the Citrus Pathogen <italic>Xanthomonas citri</italic>
</title>
<author><name sortKey="T Foli De Araujo, Fabiano" sort="T Foli De Araujo, Fabiano" uniqKey="T Foli De Araujo F" first="Fabiano" last="T Foli De Araújo">Fabiano T Foli De Araújo</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Bolanos Garcia, Victor M" sort="Bolanos Garcia, Victor M" uniqKey="Bolanos Garcia V" first="Victor M." last="Bolanos-Garcia">Victor M. Bolanos-Garcia</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pereira, Cristiane T" sort="Pereira, Cristiane T" uniqKey="Pereira C" first="Cristiane T." last="Pereira">Cristiane T. Pereira</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Sanches, Mario" sort="Sanches, Mario" uniqKey="Sanches M" first="Mario" last="Sanches">Mario Sanches</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Monte Sinai Hospital, Toronto, Ontario, Canada</addr-line>
</nlm:aff>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Monte Sinai Hospital, Toronto, Ontario</wicri:regionArea>
<wicri:noRegion>Ontario</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oshiro, Elisa E" sort="Oshiro, Elisa E" uniqKey="Oshiro E" first="Elisa E." last="Oshiro">Elisa E. Oshiro</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Ferreira, Rita C C" sort="Ferreira, Rita C C" uniqKey="Ferreira R" first="Rita C. C." last="Ferreira">Rita C. C. Ferreira</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Chigardze, Dimitri Y" sort="Chigardze, Dimitri Y" uniqKey="Chigardze D" first="Dimitri Y." last="Chigardze">Dimitri Y. Chigardze</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barbosa, Joao Alexandre Goncalves" sort="Barbosa, Joao Alexandre Goncalves" uniqKey="Barbosa J" first="João Alexandre Gonçalves" last="Barbosa">João Alexandre Gonçalves Barbosa</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><addr-line>Departamento de Genética, Universidade Católica de Brasília, Brasilia, Districto Federal, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Genética, Universidade Católica de Brasília, Brasilia, Districto Federal</wicri:regionArea>
<wicri:noRegion>Districto Federal</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="De Souza Ferreira, Luis Carlos" sort="De Souza Ferreira, Luis Carlos" uniqKey="De Souza Ferreira L" first="Luís Carlos" last="De Souza Ferreira">Luís Carlos De Souza Ferreira</name>
<affiliation wicri:level="4"><nlm:aff id="aff1"><addr-line>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Departamento de Microbiologia, Universidade de São Paulo, São Paulo, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
<orgName type="university">Université de São Paulo</orgName>
</affiliation>
</author>
<author><name sortKey="Benedetti, Celso E" sort="Benedetti, Celso E" uniqKey="Benedetti C" first="Celso E." last="Benedetti">Celso E. Benedetti</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Blundell, Tom L" sort="Blundell, Tom L" uniqKey="Blundell T" first="Tom L." last="Blundell">Tom L. Blundell</name>
<affiliation wicri:level="4"><nlm:aff id="aff2"><addr-line>Department of Biochemistry, University of Cambridge, Cambridge, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Department of Biochemistry, University of Cambridge, Cambridge</wicri:regionArea>
<orgName type="university">Université de Cambridge</orgName>
<placeName><settlement type="city">Cambridge</settlement>
<region type="country">Angleterre</region>
<region type="région" nuts="1">Angleterre de l'Est</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Balan, Andrea" sort="Balan, Andrea" uniqKey="Balan A" first="Andrea" last="Balan">Andrea Balan</name>
<affiliation wicri:level="3"><nlm:aff id="aff3"><addr-line>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo, Brazil</addr-line>
</nlm:aff>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>Laboratório Nacional de Biociências, Centro de Pesquisa em Energia e Materiais, Campinas, São Paulo</wicri:regionArea>
<placeName><settlement type="city">São Paulo</settlement>
<region type="state">État de São Paulo</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alkanesulfonates (chemistry)</term>
<term>Alkanesulfonates (metabolism)</term>
<term>Amino Acid Sequence</term>
<term>Bacterial Proteins (chemistry)</term>
<term>Bacterial Proteins (genetics)</term>
<term>Bacterial Proteins (physiology)</term>
<term>Binding Sites</term>
<term>Carrier Proteins (chemistry)</term>
<term>Carrier Proteins (genetics)</term>
<term>Carrier Proteins (physiology)</term>
<term>Citrus sinensis (growth & development)</term>
<term>Citrus sinensis (metabolism)</term>
<term>Citrus sinensis (microbiology)</term>
<term>Models, Molecular</term>
<term>Molecular Sequence Data</term>
<term>Plant Diseases (microbiology)</term>
<term>Polysaccharides, Bacterial (metabolism)</term>
<term>Sequence Alignment</term>
<term>Virulence</term>
<term>X-Ray Diffraction</term>
<term>Xanthomonas (genetics)</term>
<term>Xanthomonas (metabolism)</term>
<term>Xanthomonas (pathogenicity)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Alkanesulfonates</term>
<term>Bacterial Proteins</term>
<term>Carrier Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Bacterial Proteins</term>
<term>Carrier Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Alkanesulfonates</term>
<term>Polysaccharides, Bacterial</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Bacterial Proteins</term>
<term>Carrier Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Xanthomonas</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Citrus sinensis</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Citrus sinensis</term>
<term>Xanthomonas</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Citrus sinensis</term>
<term>Plant Diseases</term>
</keywords>
<keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Xanthomonas</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Amino Acid Sequence</term>
<term>Binding Sites</term>
<term>Models, Molecular</term>
<term>Molecular Sequence Data</term>
<term>Sequence Alignment</term>
<term>Virulence</term>
<term>X-Ray Diffraction</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>The uptake of sulphur-containing compounds plays a pivotal role in the physiology of bacteria that live in aerobic soils where organosulfur compounds such as sulphonates and sulphate esters represent more than 95% of the available sulphur. Until now, no information has been available on the uptake of sulphonates by bacterial plant pathogens, particularly those of the <italic>Xanthomonas</italic>
genus, which encompasses several pathogenic species. In the present study, we characterised the alkanesulphonate uptake system (Ssu) of <italic>Xanthomonas axonopodis</italic>
pv. <italic>citri</italic>
306 strain (<italic>X. citri</italic>
), the etiological agent of citrus canker.</p>
</sec>
<sec><title>Methodology/Principal Findings</title>
<p>A single operon-like gene cluster (<italic>ssuEDACB</italic>
) that encodes both the sulphur uptake system and enzymes involved in desulphurisation was detected in the genomes of <italic>X. citri</italic>
and of the closely related species. We characterised <italic>X. citri</italic>
SsuA protein, a periplasmic alkanesulphonate-binding protein that, together with SsuC and SsuB, defines the alkanesulphonate uptake system. The crystal structure of SsuA bound to MOPS, MES and HEPES, which is herein described for the first time, provides evidence for the importance of a conserved dipole in sulphate group coordination, identifies specific amino acids interacting with the sulphate group and shows the presence of a rather large binding pocket that explains the rather wide range of molecules recognised by the protein. Isolation of an isogenic <italic>ssuA-</italic>
knockout derivative of the <italic>X. citri</italic>
306 strain showed that disruption of alkanesulphonate uptake affects both xanthan gum production and generation of canker lesions in sweet orange leaves.</p>
</sec>
<sec><title>Conclusions/Significance</title>
<p>The present study unravels unique structural and functional features of the <italic>X. citri</italic>
SsuA protein and provides the first experimental evidence that an ABC uptake system affects the virulence of this phytopathogen.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kertesz, Ma" uniqKey="Kertesz M">MA Kertesz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kertesz, Ma" uniqKey="Kertesz M">MA Kertesz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Der, Ploegjr" uniqKey="Van Der P">PloegJR Van der</name>
</author>
<author><name sortKey="Eichorn, E" uniqKey="Eichorn E">E Eichorn</name>
</author>
<author><name sortKey="Leisinger, T" uniqKey="Leisinger T">T Leisinger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Autry, Ar" uniqKey="Autry A">AR Autry</name>
</author>
<author><name sortKey="Fitzgerald, Jw" uniqKey="Fitzgerald J">JW Fitzgerald</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Der, Ploegjr" uniqKey="Van Der P">PloegJR van der</name>
</author>
<author><name sortKey="Weiss, Ma" uniqKey="Weiss M">MA Weiss</name>
</author>
<author><name sortKey="Saller, E" uniqKey="Saller E">E Saller</name>
</author>
<author><name sortKey="Nashimoto, H" uniqKey="Nashimoto H">H Nashimoto</name>
</author>
<author><name sortKey="Saito, N" uniqKey="Saito N">N Saito</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Der, Ploegjr" uniqKey="Van Der P">PloegJR van der</name>
</author>
<author><name sortKey="Cummings, Nj" uniqKey="Cummings N">NJ Cummings</name>
</author>
<author><name sortKey="Leisinger, T" uniqKey="Leisinger T">T Leisinger</name>
</author>
<author><name sortKey="Connerton, If" uniqKey="Connerton I">IF Connerton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Van Der, Ploegjr" uniqKey="Van Der P">PloegJR Van der</name>
</author>
<author><name sortKey="Iwanicka Nowicka, R" uniqKey="Iwanicka Nowicka R">R Iwanicka-Nowicka</name>
</author>
<author><name sortKey="Bykowski, T" uniqKey="Bykowski T">T Bykowski</name>
</author>
<author><name sortKey="Hryniewicz, Mm" uniqKey="Hryniewicz M">MM Hryniewicz</name>
</author>
<author><name sortKey="Leisinger, T" uniqKey="Leisinger T">T Leisinger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Beale, J" uniqKey="Beale J">J Beale</name>
</author>
<author><name sortKey="Lee, Sy" uniqKey="Lee S">SY Lee</name>
</author>
<author><name sortKey="Iwata, S" uniqKey="Iwata S">S Iwata</name>
</author>
<author><name sortKey="Beis, K" uniqKey="Beis K">K Beis</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kahnert, A" uniqKey="Kahnert A">A Kahnert</name>
</author>
<author><name sortKey="Vermeij, P" uniqKey="Vermeij P">P Vermeij</name>
</author>
<author><name sortKey="Wietek, C" uniqKey="Wietek C">C Wietek</name>
</author>
<author><name sortKey="James, P" uniqKey="James P">P James</name>
</author>
<author><name sortKey="Leisinger, T" uniqKey="Leisinger T">T Leisinger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Parkinson, N" uniqKey="Parkinson N">N Parkinson</name>
</author>
<author><name sortKey="Aritua, V" uniqKey="Aritua V">V Aritua</name>
</author>
<author><name sortKey="Heeney, J" uniqKey="Heeney J">J Heeney</name>
</author>
<author><name sortKey="Cowie, C" uniqKey="Cowie C">C Cowie</name>
</author>
<author><name sortKey="Bew, J" uniqKey="Bew J">J Bew</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ryan, Rp" uniqKey="Ryan R">RP Ryan</name>
</author>
<author><name sortKey="Vorholter, Fj" uniqKey="Vorholter F">FJ Vorhölter</name>
</author>
<author><name sortKey="Potnis, N" uniqKey="Potnis N">N Potnis</name>
</author>
<author><name sortKey="Jones, Jb" uniqKey="Jones J">JB Jones</name>
</author>
<author><name sortKey="Van Sluys, Ma" uniqKey="Van Sluys M">MA Van Sluys</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gottwald, Tr" uniqKey="Gottwald T">TR Gottwald</name>
</author>
<author><name sortKey="Graham, Jh" uniqKey="Graham J">JH Graham</name>
</author>
<author><name sortKey="Civerolo, El" uniqKey="Civerolo E">EL Civerolo</name>
</author>
<author><name sortKey="Barret, Hc" uniqKey="Barret H">HC Barret</name>
</author>
<author><name sortKey="Hearn, Cj" uniqKey="Hearn C">CJ Hearn</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brunings, Am" uniqKey="Brunings A">AM Brunings</name>
</author>
<author><name sortKey="Gabriel, Dw" uniqKey="Gabriel D">DW Gabriel</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vojnov, Aa" uniqKey="Vojnov A">AA Vojnov</name>
</author>
<author><name sortKey="Zorreguieta, A" uniqKey="Zorreguieta A">A Zorreguieta</name>
</author>
<author><name sortKey="Dow, Jm" uniqKey="Dow J">JM Dow</name>
</author>
<author><name sortKey="Daniels, Mj" uniqKey="Daniels M">MJ Daniels</name>
</author>
<author><name sortKey="Dankert, M" uniqKey="Dankert M">M Dankert</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Crossman, L" uniqKey="Crossman L">L Crossman</name>
</author>
<author><name sortKey="Dow, Jm" uniqKey="Dow J">JM Dow</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Guo, Y" uniqKey="Guo Y">Y Guo</name>
</author>
<author><name sortKey="Sagaram, Us" uniqKey="Sagaram U">US Sagaram</name>
</author>
<author><name sortKey="Kim, Js" uniqKey="Kim J">JS Kim</name>
</author>
<author><name sortKey="Wang, N" uniqKey="Wang N">N Wang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cooke, Am" uniqKey="Cooke A">AM Cooke</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eichhorn, E" uniqKey="Eichhorn E">E Eichhorn</name>
</author>
<author><name sortKey="Van Der, Ploegjr" uniqKey="Van Der P">PloegJR van der</name>
</author>
<author><name sortKey="Leisinger, T" uniqKey="Leisinger T">T Leisinger</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="He, Jj" uniqKey="He J">JJ He</name>
</author>
<author><name sortKey="Quiocho, Fa" uniqKey="Quiocho F">FA Quiocho</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Wang, Z" uniqKey="Wang Z">Z Wang</name>
</author>
<author><name sortKey="Luecke, H" uniqKey="Luecke H">H Luecke</name>
</author>
<author><name sortKey="Yao, N" uniqKey="Yao N">N Yao</name>
</author>
<author><name sortKey="Quiocho, Fa" uniqKey="Quiocho F">FA Quiocho</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Koropatkin, Nm" uniqKey="Koropatkin N">NM Koropatkin</name>
</author>
<author><name sortKey="Pakrasi, Hb" uniqKey="Pakrasi H">HB Pakrasi</name>
</author>
<author><name sortKey="Smith, Tj" uniqKey="Smith T">TJ Smith</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kopriva, S" uniqKey="Kopriva S">S Kopriva</name>
</author>
<author><name sortKey="Koprivova, A" uniqKey="Koprivova A">A Koprivova</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Denny, Tp" uniqKey="Denny T">TP Denny</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rigano, La" uniqKey="Rigano L">LA Rigano</name>
</author>
<author><name sortKey="Siciliano, F" uniqKey="Siciliano F">F Siciliano</name>
</author>
<author><name sortKey="Enrique, J" uniqKey="Enrique J">J Enrique</name>
</author>
<author><name sortKey="Sendin, L" uniqKey="Sendin L">L Sendín</name>
</author>
<author><name sortKey="Filippone, P" uniqKey="Filippone P">P Filippone</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kemp, Bp" uniqKey="Kemp B">BP Kemp</name>
</author>
<author><name sortKey="Horne, J" uniqKey="Horne J">J Horne</name>
</author>
<author><name sortKey="Bryant, A" uniqKey="Bryant A">A Bryant</name>
</author>
<author><name sortKey="Cooper, Rm" uniqKey="Cooper R">RM Cooper</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vanderslice, Rw" uniqKey="Vanderslice R">RW Vanderslice</name>
</author>
<author><name sortKey="Doherty, Dh" uniqKey="Doherty D">DH Doherty</name>
</author>
<author><name sortKey="Capage, Ma" uniqKey="Capage M">MA Capage</name>
</author>
<author><name sortKey="Betlach, Mr" uniqKey="Betlach M">MR Betlach</name>
</author>
<author><name sortKey="Hassler, Ra" uniqKey="Hassler R">RA Hassler</name>
</author>
<author><name sortKey="Crescenzi, V" uniqKey="Crescenzi V">V Crescenzi</name>
</author>
<author><name sortKey="Dea, Icm" uniqKey="Dea I">ICM Dea</name>
</author>
<author><name sortKey="Paoletti, S" uniqKey="Paoletti S">S Paoletti</name>
</author>
<author><name sortKey="Stivala, Ss" uniqKey="Stivala S">SS Stivala</name>
</author>
<author><name sortKey="Sutherland, Iw" uniqKey="Sutherland I">IW Sutherland</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Thompson, Dg" uniqKey="Thompson D">DG Thompson</name>
</author>
<author><name sortKey="Higgins, Jd" uniqKey="Higgins J">JD Higgins</name>
</author>
<author><name sortKey="Gibson, Tj" uniqKey="Gibson T">TJ Gibson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Saitou, N" uniqKey="Saitou N">N Saitou</name>
</author>
<author><name sortKey="Nei, M" uniqKey="Nei M">M Nei</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tamura, K" uniqKey="Tamura K">K Tamura</name>
</author>
<author><name sortKey="Peterson, D" uniqKey="Peterson D">D Peterson</name>
</author>
<author><name sortKey="Peterson, N" uniqKey="Peterson N">N Peterson</name>
</author>
<author><name sortKey="Stecher, G" uniqKey="Stecher G">G Stecher</name>
</author>
<author><name sortKey="Nei, M" uniqKey="Nei M">M Nei</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Edelhoch, H" uniqKey="Edelhoch H">H Edelhoch</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Deleage, G" uniqKey="Deleage G">G Deleage</name>
</author>
<author><name sortKey="Geourjon, C" uniqKey="Geourjon C">C Geourjon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Polikarpov, I" uniqKey="Polikarpov I">I Polikarpov</name>
</author>
<author><name sortKey="Oliva, G" uniqKey="Oliva G">G Oliva</name>
</author>
<author><name sortKey="Castellano, Ee" uniqKey="Castellano E">EE Castellano</name>
</author>
<author><name sortKey="Garratt, Rc" uniqKey="Garratt R">RC Garratt</name>
</author>
<author><name sortKey="Arruda, P" uniqKey="Arruda P">P Arruda</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kabsch, W" uniqKey="Kabsch W">W Kabsch</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Vonrhein, C" uniqKey="Vonrhein C">C Vonrhein</name>
</author>
<author><name sortKey="Blanc, E" uniqKey="Blanc E">E Blanc</name>
</author>
<author><name sortKey="Roversi, P" uniqKey="Roversi P">P Roversi</name>
</author>
<author><name sortKey="Bricogne, G" uniqKey="Bricogne G">G Bricogne</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sheldrick, Gm" uniqKey="Sheldrick G">GM Sheldrick</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Murshudov, Gn" uniqKey="Murshudov G">GN Murshudov</name>
</author>
<author><name sortKey="Vagin, Aa" uniqKey="Vagin A">AA Vagin</name>
</author>
<author><name sortKey="Dodson, Ej" uniqKey="Dodson E">EJ Dodson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Oshiro, Ee" uniqKey="Oshiro E">EE Oshiro</name>
</author>
<author><name sortKey="Nepomuceno, Rsl" uniqKey="Nepomuceno R">RSL Nepomuceno</name>
</author>
<author><name sortKey="Faria, Jb" uniqKey="Faria J">JB Faria</name>
</author>
<author><name sortKey="Ferreira, Lcs" uniqKey="Ferreira L">LCS Ferreira</name>
</author>
<author><name sortKey="Ferreira, Rcc" uniqKey="Ferreira R">RCC Ferreira</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Baldini, Rl" uniqKey="Baldini R">RL Baldini</name>
</author>
<author><name sortKey="Tahara, St" uniqKey="Tahara S">ST Tahara</name>
</author>
<author><name sortKey="Rosato, Yb" uniqKey="Rosato Y">YB Rosato</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Cernadas, Ra" uniqKey="Cernadas R">RA Cernadas</name>
</author>
<author><name sortKey="Camillo, Lr" uniqKey="Camillo L">LR Camillo</name>
</author>
<author><name sortKey="Benedetti, Ce" uniqKey="Benedetti C">CE Benedetti</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Brésil</li>
<li>Canada</li>
<li>Royaume-Uni</li>
</country>
<region><li>Angleterre</li>
<li>Angleterre de l'Est</li>
<li>État de São Paulo</li>
</region>
<settlement><li>Cambridge</li>
<li>São Paulo</li>
</settlement>
<orgName><li>Université de Cambridge</li>
<li>Université de São Paulo</li>
</orgName>
</list>
<tree><country name="Brésil"><region name="État de São Paulo"><name sortKey="T Foli De Araujo, Fabiano" sort="T Foli De Araujo, Fabiano" uniqKey="T Foli De Araujo F" first="Fabiano" last="T Foli De Araújo">Fabiano T Foli De Araújo</name>
</region>
<name sortKey="Balan, Andrea" sort="Balan, Andrea" uniqKey="Balan A" first="Andrea" last="Balan">Andrea Balan</name>
<name sortKey="Barbosa, Joao Alexandre Goncalves" sort="Barbosa, Joao Alexandre Goncalves" uniqKey="Barbosa J" first="João Alexandre Gonçalves" last="Barbosa">João Alexandre Gonçalves Barbosa</name>
<name sortKey="Benedetti, Celso E" sort="Benedetti, Celso E" uniqKey="Benedetti C" first="Celso E." last="Benedetti">Celso E. Benedetti</name>
<name sortKey="De Souza Ferreira, Luis Carlos" sort="De Souza Ferreira, Luis Carlos" uniqKey="De Souza Ferreira L" first="Luís Carlos" last="De Souza Ferreira">Luís Carlos De Souza Ferreira</name>
<name sortKey="Ferreira, Rita C C" sort="Ferreira, Rita C C" uniqKey="Ferreira R" first="Rita C. C." last="Ferreira">Rita C. C. Ferreira</name>
<name sortKey="Oshiro, Elisa E" sort="Oshiro, Elisa E" uniqKey="Oshiro E" first="Elisa E." last="Oshiro">Elisa E. Oshiro</name>
<name sortKey="Pereira, Cristiane T" sort="Pereira, Cristiane T" uniqKey="Pereira C" first="Cristiane T." last="Pereira">Cristiane T. Pereira</name>
</country>
<country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Bolanos Garcia, Victor M" sort="Bolanos Garcia, Victor M" uniqKey="Bolanos Garcia V" first="Victor M." last="Bolanos-Garcia">Victor M. Bolanos-Garcia</name>
</region>
<name sortKey="Blundell, Tom L" sort="Blundell, Tom L" uniqKey="Blundell T" first="Tom L." last="Blundell">Tom L. Blundell</name>
<name sortKey="Chigardze, Dimitri Y" sort="Chigardze, Dimitri Y" uniqKey="Chigardze D" first="Dimitri Y." last="Chigardze">Dimitri Y. Chigardze</name>
</country>
<country name="Canada"><noRegion><name sortKey="Sanches, Mario" sort="Sanches, Mario" uniqKey="Sanches M" first="Mario" last="Sanches">Mario Sanches</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D19 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000D19 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Bois |area= OrangerV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:3839906 |texte= Structural and Physiological Analyses of the Alkanesulphonate-Binding Protein (SsuA) of the Citrus Pathogen Xanthomonas citri }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:24282519" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a OrangerV1
![]() | This area was generated with Dilib version V0.6.25. | ![]() |