Effect of Hibiscus sabdariffa extract on high fat diet–induced obesity and liver damage in hamsters
Identifieur interne : 000686 ( Main/Exploration ); précédent : 000685; suivant : 000687Effect of Hibiscus sabdariffa extract on high fat diet–induced obesity and liver damage in hamsters
Auteurs : To-Wei Huang [Taïwan] ; Chia-Ling Chang [Taïwan] ; Erl-Shyh Kao [Taïwan] ; Jenq-Horng Lin [Taïwan]Source :
- Food & Nutrition Research [ 1654-6628 ] ; 2015.
Abstract
Obesity is a chronic metabolic disorder associated with an increase in adipogenesis and often accompanied with fatty liver disease.
In this study, we investigated the anti-obesity effects of
Eight-weeks-old male mice were divided into six groups (
Mesocricetus auratus hamster fed with a high-fat diet developed symptoms of obesity, as determined from their body weight change and from their plasma lipid levels. Meanwhile, HSE treatment reduced fat accumulation in the livers of hamsters fed with HFD in a concentration-dependent manner. Administration of HSE reduced the levels of liver cholesterol and triglycerides, which were elevated by HFD. Analysis of the effect of HSE on paraoxonase 1, an antioxidant liver enzyme, revealed that HSE potentially regulates lipid peroxides and protects organs from oxidation-associated damage. The markers of liver damage such as serum alanine aminotransferase and aspartate aminotransferase levels that were elevated by HFD were also reduced on HSE treatment. The effects of HSE were as effective as treatment with anthocyanin; therefore the anthocyanins present in the HSE may play a crucial role in the protection established against HFD-induced obesity.
In conclusion HSE administration constitutes an effective and viable treatment strategy against the development and consequences of obesity.
Url:
DOI: 10.3402/fnr.v59.29018
PubMed: 26475512
PubMed Central: 4608971
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000057
- to stream Pmc, to step Curation: 000057
- to stream Pmc, to step Checkpoint: 000535
- to stream Ncbi, to step Merge: 001D60
- to stream Ncbi, to step Curation: 001D60
- to stream Ncbi, to step Checkpoint: 001D60
- to stream Main, to step Merge: 000686
- to stream Main, to step Curation: 000686
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of <italic>Hibiscus sabdariffa</italic> extract on high fat diet–induced obesity and liver damage in hamsters</title><author><name sortKey="Huang, To Wei" sort="Huang, To Wei" uniqKey="Huang T" first="To-Wei" last="Huang">To-Wei Huang</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Life Sciences, National Chung Hsing University, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author><author><name sortKey="Chang, Chia Ling" sort="Chang, Chia Ling" uniqKey="Chang C" first="Chia-Ling" last="Chang">Chia-Ling Chang</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Department of Nursing, China Medical University Hospital, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Nursing, China Medical University Hospital, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author><author><name sortKey="Kao, Erl Shyh" sort="Kao, Erl Shyh" uniqKey="Kao E" first="Erl-Shyh" last="Kao">Erl-Shyh Kao</name><affiliation wicri:level="1"><nlm:aff id="AF0003">Department of Beauty Science and Graduate Institute of Beauty Science Technology, Chienkuo Technology University, Changhua, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Beauty Science and Graduate Institute of Beauty Science Technology, Chienkuo Technology University, Changhua</wicri:regionArea><wicri:noRegion>Changhua</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Jenq Horng" sort="Lin, Jenq Horng" uniqKey="Lin J" first="Jenq-Horng" last="Lin">Jenq-Horng Lin</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Life Sciences, National Chung Hsing University, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26475512</idno><idno type="pmc">4608971</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608971</idno><idno type="RBID">PMC:4608971</idno><idno type="doi">10.3402/fnr.v59.29018</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000057</idno><idno type="wicri:Area/Pmc/Curation">000057</idno><idno type="wicri:Area/Pmc/Checkpoint">000535</idno><idno type="wicri:Area/Ncbi/Merge">001D60</idno><idno type="wicri:Area/Ncbi/Curation">001D60</idno><idno type="wicri:Area/Ncbi/Checkpoint">001D60</idno><idno type="wicri:Area/Main/Merge">000686</idno><idno type="wicri:Area/Main/Curation">000686</idno><idno type="wicri:Area/Main/Exploration">000686</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effect of <italic>Hibiscus sabdariffa</italic> extract on high fat diet–induced obesity and liver damage in hamsters</title><author><name sortKey="Huang, To Wei" sort="Huang, To Wei" uniqKey="Huang T" first="To-Wei" last="Huang">To-Wei Huang</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Life Sciences, National Chung Hsing University, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author><author><name sortKey="Chang, Chia Ling" sort="Chang, Chia Ling" uniqKey="Chang C" first="Chia-Ling" last="Chang">Chia-Ling Chang</name><affiliation wicri:level="1"><nlm:aff id="AF0002">Department of Nursing, China Medical University Hospital, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Nursing, China Medical University Hospital, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author><author><name sortKey="Kao, Erl Shyh" sort="Kao, Erl Shyh" uniqKey="Kao E" first="Erl-Shyh" last="Kao">Erl-Shyh Kao</name><affiliation wicri:level="1"><nlm:aff id="AF0003">Department of Beauty Science and Graduate Institute of Beauty Science Technology, Chienkuo Technology University, Changhua, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Beauty Science and Graduate Institute of Beauty Science Technology, Chienkuo Technology University, Changhua</wicri:regionArea><wicri:noRegion>Changhua</wicri:noRegion></affiliation></author><author><name sortKey="Lin, Jenq Horng" sort="Lin, Jenq Horng" uniqKey="Lin J" first="Jenq-Horng" last="Lin">Jenq-Horng Lin</name><affiliation wicri:level="1"><nlm:aff id="AF0001">Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan</nlm:aff><country xml:lang="fr">Taïwan</country><wicri:regionArea>Department of Life Sciences, National Chung Hsing University, Taichung</wicri:regionArea><wicri:noRegion>Taichung</wicri:noRegion></affiliation></author></analytic><series><title level="j">Food & Nutrition Research</title><idno type="ISSN">1654-6628</idno><idno type="eISSN">1654-661X</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="st1"><title>Background</title><p>Obesity is a chronic metabolic disorder associated with an increase in adipogenesis and often accompanied with fatty liver disease.</p></sec><sec id="st2"><title>Objective</title><p>In this study, we investigated the anti-obesity effects of <italic>Hibiscus sabdariffa</italic> water extract (HSE) <italic>in vivo</italic>.</p></sec><sec id="st3"><title>Method</title><p>Eight-weeks-old male mice were divided into six groups (<italic>n</italic>=8 per group) and were fed either normal feed, a high fat diet (HFD), HFD supplemented with different concentrations of HSE, or HFD supplemented with anthocyanin. After 10 weeks of feeding, all the blood and livers were collected for further analysis.</p></sec><sec id="st4"><title>Results</title><p>Mesocricetus auratus hamster fed with a high-fat diet developed symptoms of obesity, as determined from their body weight change and from their plasma lipid levels. Meanwhile, HSE treatment reduced fat accumulation in the livers of hamsters fed with HFD in a concentration-dependent manner. Administration of HSE reduced the levels of liver cholesterol and triglycerides, which were elevated by HFD. Analysis of the effect of HSE on paraoxonase 1, an antioxidant liver enzyme, revealed that HSE potentially regulates lipid peroxides and protects organs from oxidation-associated damage. The markers of liver damage such as serum alanine aminotransferase and aspartate aminotransferase levels that were elevated by HFD were also reduced on HSE treatment. The effects of HSE were as effective as treatment with anthocyanin; therefore the anthocyanins present in the HSE may play a crucial role in the protection established against HFD-induced obesity.</p></sec><sec id="st5"><title>Conclusions</title><p>In conclusion HSE administration constitutes an effective and viable treatment strategy against the development and consequences of obesity.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Camp, Hs" uniqKey="Camp H">HS Camp</name></author><author><name sortKey="Ren, D" uniqKey="Ren D">D Ren</name></author><author><name sortKey="Leff, T" uniqKey="Leff T">T Leff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Holland, Wl" uniqKey="Holland W">WL Holland</name></author><author><name sortKey="Brozinick, Jt" uniqKey="Brozinick J">JT Brozinick</name></author><author><name sortKey="Wang, Lp" uniqKey="Wang L">LP Wang</name></author><author><name sortKey="Hawkins, Ed" uniqKey="Hawkins E">ED Hawkins</name></author><author><name sortKey="Sargent, Km" uniqKey="Sargent K">KM Sargent</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kubota, N" uniqKey="Kubota N">N Kubota</name></author><author><name sortKey="Terauchi, Y" uniqKey="Terauchi Y">Y Terauchi</name></author><author><name sortKey="Miki, H" uniqKey="Miki H">H Miki</name></author><author><name sortKey="Tamemoto, H" uniqKey="Tamemoto H">H Tamemoto</name></author><author><name sortKey="Yamauchi, T" uniqKey="Yamauchi T">T Yamauchi</name></author><author><name sortKey="Komeda, K" uniqKey="Komeda K">K Komeda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Park, Ej" uniqKey="Park E">EJ Park</name></author><author><name sortKey="Lee, Jh" uniqKey="Lee J">JH Lee</name></author><author><name sortKey="Yu, Gy" uniqKey="Yu G">GY Yu</name></author><author><name sortKey="He, G" uniqKey="He G">G He</name></author><author><name sortKey="Ali, Sr" uniqKey="Ali S">SR Ali</name></author><author><name sortKey="Holzer, Rg" uniqKey="Holzer R">RG Holzer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, S" uniqKey="Kim S">S Kim</name></author><author><name sortKey="Jin, Y" uniqKey="Jin Y">Y Jin</name></author><author><name sortKey="Choi, Y" uniqKey="Choi Y">Y Choi</name></author><author><name sortKey="Park, T" uniqKey="Park T">T Park</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Yj" uniqKey="Kim Y">YJ Kim</name></author><author><name sortKey="Bae, Yc" uniqKey="Bae Y">YC Bae</name></author><author><name sortKey="Suh, Kt" uniqKey="Suh K">KT Suh</name></author><author><name sortKey="Jung, Js" uniqKey="Jung J">JS Jung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Groot, H" uniqKey="De Groot H">H de Groot</name></author><author><name sortKey="Rauen, U" uniqKey="Rauen U">U Rauen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tapas, Ar" uniqKey="Tapas A">AR Tapas</name></author><author><name sortKey="Sakarkar, Dm" uniqKey="Sakarkar D">DM Sakarkar</name></author><author><name sortKey="Kakde, Rb" uniqKey="Kakde R">RB Kakde</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jung, Hs" uniqKey="Jung H">HS Jung</name></author><author><name sortKey="Lim, Y" uniqKey="Lim Y">Y Lim</name></author><author><name sortKey="Kim, Ek" uniqKey="Kim E">EK Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guo, H" uniqKey="Guo H">H Guo</name></author><author><name sortKey="Ling, W" uniqKey="Ling W">W Ling</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Diaconeasa, Z" uniqKey="Diaconeasa Z">Z Diaconeasa</name></author><author><name sortKey="Leopold, L" uniqKey="Leopold L">L Leopold</name></author><author><name sortKey="Rugina, D" uniqKey="Rugina D">D Rugina</name></author><author><name sortKey="Ayvaz, H" uniqKey="Ayvaz H">H Ayvaz</name></author><author><name sortKey="Socaciu, C" uniqKey="Socaciu C">C Socaciu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, Sj" uniqKey="Cho S">SJ Cho</name></author><author><name sortKey="Park, Hj" uniqKey="Park H">HJ Park</name></author><author><name sortKey="Jung, Uj" uniqKey="Jung U">UJ Jung</name></author><author><name sortKey="Kim, Hj" uniqKey="Kim H">HJ Kim</name></author><author><name sortKey="Moon, Bs" uniqKey="Moon B">BS Moon</name></author><author><name sortKey="Choi, Ms" uniqKey="Choi M">MS Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, S" uniqKey="Zhang S">S Zhang</name></author><author><name sortKey="Zheng, L" uniqKey="Zheng L">L Zheng</name></author><author><name sortKey="Dong, D" uniqKey="Dong D">D Dong</name></author><author><name sortKey="Xu, L" uniqKey="Xu L">L Xu</name></author><author><name sortKey="Yin, L" uniqKey="Yin L">L Yin</name></author><author><name sortKey="Qi, Y" uniqKey="Qi Y">Y Qi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jung, Ch" uniqKey="Jung C">CH Jung</name></author><author><name sortKey="Cho, I" uniqKey="Cho I">I Cho</name></author><author><name sortKey="Ahn, J" uniqKey="Ahn J">J Ahn</name></author><author><name sortKey="Jeon, Ti" uniqKey="Jeon T">TI Jeon</name></author><author><name sortKey="Ha, Ty" uniqKey="Ha T">TY Ha</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, Lx" uniqKey="Yu L">LX Yu</name></author><author><name sortKey="Yan, Hx" uniqKey="Yan H">HX Yan</name></author><author><name sortKey="Liu, Q" uniqKey="Liu Q">Q Liu</name></author><author><name sortKey="Yang, W" uniqKey="Yang W">W Yang</name></author><author><name sortKey="Wu, Hp" uniqKey="Wu H">HP Wu</name></author><author><name sortKey="Dong, W" uniqKey="Dong W">W Dong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, Ch" uniqKey="Wu C">CH Wu</name></author><author><name sortKey="Yang, My" uniqKey="Yang M">MY Yang</name></author><author><name sortKey="Chan, Kc" uniqKey="Chan K">KC Chan</name></author><author><name sortKey="Chung, Pj" uniqKey="Chung P">PJ Chung</name></author><author><name sortKey="Ou, Tt" uniqKey="Ou T">TT Ou</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yang, My" uniqKey="Yang M">MY Yang</name></author><author><name sortKey="Peng, Ch" uniqKey="Peng C">CH Peng</name></author><author><name sortKey="Chan, Kc" uniqKey="Chan K">KC Chan</name></author><author><name sortKey="Yang, Ys" uniqKey="Yang Y">YS Yang</name></author><author><name sortKey="Huang, Cn" uniqKey="Huang C">CN Huang</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Hh" uniqKey="Lin H">HH Lin</name></author><author><name sortKey="Chen, Jh" uniqKey="Chen J">JH Chen</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, Jy" uniqKey="Liu J">JY Liu</name></author><author><name sortKey="Chen, Cc" uniqKey="Chen C">CC Chen</name></author><author><name sortKey="Wang, Wh" uniqKey="Wang W">WH Wang</name></author><author><name sortKey="Hsu, Jd" uniqKey="Hsu J">JD Hsu</name></author><author><name sortKey="Yang, My" uniqKey="Yang M">MY Yang</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Tl" uniqKey="Lin T">TL Lin</name></author><author><name sortKey="Lin, Hh" uniqKey="Lin H">HH Lin</name></author><author><name sortKey="Chen, Cc" uniqKey="Chen C">CC Chen</name></author><author><name sortKey="Lin, Mc" uniqKey="Lin M">MC Lin</name></author><author><name sortKey="Chou, Mc" uniqKey="Chou M">MC Chou</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsuda, T" uniqKey="Tsuda T">T Tsuda</name></author><author><name sortKey="Horio, F" uniqKey="Horio F">F Horio</name></author><author><name sortKey="Uchida, K" uniqKey="Uchida K">K Uchida</name></author><author><name sortKey="Aoki, H" uniqKey="Aoki H">H Aoki</name></author><author><name sortKey="Osawa, T" uniqKey="Osawa T">T Osawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Titta, L" uniqKey="Titta L">L Titta</name></author><author><name sortKey="Trinei, M" uniqKey="Trinei M">M Trinei</name></author><author><name sortKey="Stendardo, M" uniqKey="Stendardo M">M Stendardo</name></author><author><name sortKey="Berniakovich, I" uniqKey="Berniakovich I">I Berniakovich</name></author><author><name sortKey="Petroni, K" uniqKey="Petroni K">K Petroni</name></author><author><name sortKey="Tonelli, C" uniqKey="Tonelli C">C Tonelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prior, Rl" uniqKey="Prior R">RL Prior</name></author><author><name sortKey="Wu, X" uniqKey="Wu X">X Wu</name></author><author><name sortKey="Gu, L" uniqKey="Gu L">L Gu</name></author><author><name sortKey="Hager, Tj" uniqKey="Hager T">TJ Hager</name></author><author><name sortKey="Hager, A" uniqKey="Hager A">A Hager</name></author><author><name sortKey="Howard, Lr" uniqKey="Howard L">LR Howard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T Wu</name></author><author><name sortKey="Qi, X" uniqKey="Qi X">X Qi</name></author><author><name sortKey="Liu, Y" uniqKey="Liu Y">Y Liu</name></author><author><name sortKey="Guo, J" uniqKey="Guo J">J Guo</name></author><author><name sortKey="Zhu, R" uniqKey="Zhu R">R Zhu</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Prior, Rl" uniqKey="Prior R">RL Prior</name></author><author><name sortKey="Wilkes, Se" uniqKey="Wilkes S">SE Wilkes</name></author><author><name sortKey="Rogers, Tr" uniqKey="Rogers T">TR Rogers</name></author><author><name sortKey="Khanal, Rc" uniqKey="Khanal R">RC Khanal</name></author><author><name sortKey="Wu, X" uniqKey="Wu X">X Wu</name></author><author><name sortKey="Howard, Lr" uniqKey="Howard L">LR Howard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T Wu</name></author><author><name sortKey="Yu, Z" uniqKey="Yu Z">Z Yu</name></author><author><name sortKey="Tang, Q" uniqKey="Tang Q">Q Tang</name></author><author><name sortKey="Song, H" uniqKey="Song H">H Song</name></author><author><name sortKey="Gao, Z" uniqKey="Gao Z">Z Gao</name></author><author><name sortKey="Chen, W" uniqKey="Chen W">W Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Hh" uniqKey="Lin H">HH Lin</name></author><author><name sortKey="Chen, Jh" uniqKey="Chen J">JH Chen</name></author><author><name sortKey="Kuo, Wh" uniqKey="Kuo W">WH Kuo</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Hh" uniqKey="Lin H">HH Lin</name></author><author><name sortKey="Huang, Hp" uniqKey="Huang H">HP Huang</name></author><author><name sortKey="Huang, Cc" uniqKey="Huang C">CC Huang</name></author><author><name sortKey="Chen, Jh" uniqKey="Chen J">JH Chen</name></author><author><name sortKey="Wang, Cj" uniqKey="Wang C">CJ Wang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kopelman, Pg" uniqKey="Kopelman P">PG Kopelman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Yw" uniqKey="Wang Y">YW Wang</name></author><author><name sortKey="Jones, Pjh" uniqKey="Jones P">PJH Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rule, Dc" uniqKey="Rule D">DC Rule</name></author><author><name sortKey="Liebman, M" uniqKey="Liebman M">M Liebman</name></author><author><name sortKey="Liang, Yb" uniqKey="Liang Y">YB Liang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Onat, A" uniqKey="Onat A">A Onat</name></author><author><name sortKey="Sari, I" uniqKey="Sari I">I Sari</name></author><author><name sortKey="Yazici, M" uniqKey="Yazici M">M Yazici</name></author><author><name sortKey="Can, G" uniqKey="Can G">G Can</name></author><author><name sortKey="Hergenc, G" uniqKey="Hergenc G">G Hergenc</name></author><author><name sortKey="Avci, Gs" uniqKey="Avci G">GS Avci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aviram, M" uniqKey="Aviram M">M Aviram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fuhrman, B" uniqKey="Fuhrman B">B Fuhrman</name></author><author><name sortKey="Aviram, M" uniqKey="Aviram M">M Aviram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crosignani, A" uniqKey="Crosignani A">A Crosignani</name></author><author><name sortKey="Zuin, M" uniqKey="Zuin M">M Zuin</name></author><author><name sortKey="Allocca, M" uniqKey="Allocca M">M Allocca</name></author><author><name sortKey="Del Puppo, M" uniqKey="Del Puppo M">M Del Puppo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lotito, Sb" uniqKey="Lotito S">SB Lotito</name></author><author><name sortKey="Frei, B" uniqKey="Frei B">B Frei</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aviram, M" uniqKey="Aviram M">M Aviram</name></author><author><name sortKey="Rosenblat, M" uniqKey="Rosenblat M">M Rosenblat</name></author><author><name sortKey="Gaitini, D" uniqKey="Gaitini D">D Gaitini</name></author><author><name sortKey="Nitecki, S" uniqKey="Nitecki S">S Nitecki</name></author><author><name sortKey="Hoffman, A" uniqKey="Hoffman A">A Hoffman</name></author><author><name sortKey="Dornfeld, L" uniqKey="Dornfeld L">L Dornfeld</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lanthier, N" uniqKey="Lanthier N">N Lanthier</name></author><author><name sortKey="Molendi Coste, O" uniqKey="Molendi Coste O">O Molendi-Coste</name></author><author><name sortKey="Cani, Pd" uniqKey="Cani P">PD Cani</name></author><author><name sortKey="Van Rooijen, N" uniqKey="Van Rooijen N">N van Rooijen</name></author><author><name sortKey="Horsmans, Y" uniqKey="Horsmans Y">Y Horsmans</name></author><author><name sortKey="Leclercq, Ia" uniqKey="Leclercq I">IA Leclercq</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Castro, Ugm" uniqKey="De Castro U">UGM de Castro</name></author><author><name sortKey="Dos Santos, Ras" uniqKey="Dos Santos R">RAS dos Santos</name></author><author><name sortKey="Silva, Me" uniqKey="Silva M">ME Silva</name></author><author><name sortKey="De Lima, Wg" uniqKey="De Lima W">WG de Lima</name></author><author><name sortKey="Campagnole Santos, Mj" uniqKey="Campagnole Santos M">MJ Campagnole-Santos</name></author><author><name sortKey="Alzamora, Ac" uniqKey="Alzamora A">AC Alzamora</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jiang, Y" uniqKey="Jiang Y">Y Jiang</name></author><author><name sortKey="Zhao, My" uniqKey="Zhao M">MY Zhao</name></author><author><name sortKey="An, W" uniqKey="An W">W An</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Srivastava, Ar" uniqKey="Srivastava A">AR Srivastava</name></author><author><name sortKey="Kumar, S" uniqKey="Kumar S">S Kumar</name></author><author><name sortKey="Agarwal, Gg" uniqKey="Agarwal G">GG Agarwal</name></author><author><name sortKey="Ranjan, P" uniqKey="Ranjan P">P Ranjan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chapman, Se" uniqKey="Chapman S">SE Chapman</name></author><author><name sortKey="Hostutler, Ra" uniqKey="Hostutler R">RA Hostutler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Ll" uniqKey="Wang L">LL Wang</name></author><author><name sortKey="Meng, Xj" uniqKey="Meng X">XJ Meng</name></author><author><name sortKey="Zhang, Fq" uniqKey="Zhang F">FQ Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Vial, G" uniqKey="Vial G">G Vial</name></author><author><name sortKey="Dubouchaud, H" uniqKey="Dubouchaud H">H Dubouchaud</name></author><author><name sortKey="Couturier, K" uniqKey="Couturier K">K Couturier</name></author><author><name sortKey="Cottet Rousselle, C" uniqKey="Cottet Rousselle C">C Cottet-Rousselle</name></author><author><name sortKey="Taleux, N" uniqKey="Taleux N">N Taleux</name></author><author><name sortKey="Athias, A" uniqKey="Athias A">A Athias</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tian, L" uniqKey="Tian L">L Tian</name></author><author><name sortKey="Shi, X" uniqKey="Shi X">X Shi</name></author><author><name sortKey="Yu, L" uniqKey="Yu L">L Yu</name></author><author><name sortKey="Zhu, J" uniqKey="Zhu J">J Zhu</name></author><author><name sortKey="Ma, R" uniqKey="Ma R">R Ma</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y Cui</name></author><author><name sortKey="Yang, X" uniqKey="Yang X">X Yang</name></author><author><name sortKey="Lu, X" uniqKey="Lu X">X Lu</name></author><author><name sortKey="Chen, J" uniqKey="Chen J">J Chen</name></author><author><name sortKey="Zhao, Y" uniqKey="Zhao Y">Y Zhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seeram, Np" uniqKey="Seeram N">NP Seeram</name></author><author><name sortKey="Aviram, M" uniqKey="Aviram M">M Aviram</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Henning, Sm" uniqKey="Henning S">SM Henning</name></author><author><name sortKey="Feng, L" uniqKey="Feng L">L Feng</name></author><author><name sortKey="Dreher, M" uniqKey="Dreher M">M Dreher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mukherjee, S" uniqKey="Mukherjee S">S Mukherjee</name></author><author><name sortKey="Ghosh, S" uniqKey="Ghosh S">S Ghosh</name></author><author><name sortKey="Choudhury, S" uniqKey="Choudhury S">S Choudhury</name></author><author><name sortKey="Adhikary, A" uniqKey="Adhikary A">A Adhikary</name></author><author><name sortKey="Manna, K" uniqKey="Manna K">K Manna</name></author><author><name sortKey="Dey, S" uniqKey="Dey S">S Dey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aprikian, O" uniqKey="Aprikian O">O Aprikian</name></author><author><name sortKey="Busserolles, J" uniqKey="Busserolles J">J Busserolles</name></author><author><name sortKey="Manach, C" uniqKey="Manach C">C Manach</name></author><author><name sortKey="Mazur, A" uniqKey="Mazur A">A Mazur</name></author><author><name sortKey="Morand, C" uniqKey="Morand C">C Morand</name></author><author><name sortKey="Davicco, Mj" uniqKey="Davicco M">MJ Davicco</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodrigues, Ad" uniqKey="Rodrigues A">AD Rodrigues</name></author><author><name sortKey="Scheffel, Tb" uniqKey="Scheffel T">TB Scheffel</name></author><author><name sortKey="Scola, G" uniqKey="Scola G">G Scola</name></author><author><name sortKey="Dos Santos, Mt" uniqKey="Dos Santos M">MT Dos Santos</name></author><author><name sortKey="Fank, B" uniqKey="Fank B">B Fank</name></author><author><name sortKey="Dani, C" uniqKey="Dani C">C Dani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heber, D" uniqKey="Heber D">D Heber</name></author><author><name sortKey="Zhang, Y" uniqKey="Zhang Y">Y Zhang</name></author><author><name sortKey="Yang, J" uniqKey="Yang J">J Yang</name></author><author><name sortKey="Ma, Je" uniqKey="Ma J">JE Ma</name></author><author><name sortKey="Henning, Sm" uniqKey="Henning S">SM Henning</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cui, Y" uniqKey="Cui Y">Y Cui</name></author><author><name sortKey="Wang, Xl" uniqKey="Wang X">XL Wang</name></author><author><name sortKey="Xue, J" uniqKey="Xue J">J Xue</name></author><author><name sortKey="Liu, Jy" uniqKey="Liu J">JY Liu</name></author><author><name sortKey="Xie, Ml" uniqKey="Xie M">ML Xie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lin, Yl" uniqKey="Lin Y">YL Lin</name></author><author><name sortKey="Chang, Yy" uniqKey="Chang Y">YY Chang</name></author><author><name sortKey="Yang, Dj" uniqKey="Yang D">DJ Yang</name></author><author><name sortKey="Tzang, Bs" uniqKey="Tzang B">BS Tzang</name></author><author><name sortKey="Chen, Yc" uniqKey="Chen Y">YC Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, Lf" uniqKey="Wang L">LF Wang</name></author><author><name sortKey="Sun, J" uniqKey="Sun J">J Sun</name></author><author><name sortKey="Yi, Qd" uniqKey="Yi Q">QD Yi</name></author><author><name sortKey="Wang, Xf" uniqKey="Wang X">XF Wang</name></author><author><name sortKey="Ju, Xr" uniqKey="Ju X">XR Ju</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zou, Yp" uniqKey="Zou Y">YP Zou</name></author><author><name sortKey="Lu, Yh" uniqKey="Lu Y">YH Lu</name></author><author><name sortKey="Wei, Dz" uniqKey="Wei D">DZ Wei</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Huang, To Wei" sort="Huang, To Wei" uniqKey="Huang T" first="To-Wei" last="Huang">To-Wei Huang</name></noRegion><name sortKey="Chang, Chia Ling" sort="Chang, Chia Ling" uniqKey="Chang C" first="Chia-Ling" last="Chang">Chia-Ling Chang</name><name sortKey="Kao, Erl Shyh" sort="Kao, Erl Shyh" uniqKey="Kao E" first="Erl-Shyh" last="Kao">Erl-Shyh Kao</name><name sortKey="Lin, Jenq Horng" sort="Lin, Jenq Horng" uniqKey="Lin J" first="Jenq-Horng" last="Lin">Jenq-Horng Lin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Bois/explor/OrangerV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000686 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000686 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Bois
|area= OrangerV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:4608971
|texte= Effect of Hibiscus sabdariffa extract on high fat diet–induced obesity and liver damage in hamsters
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:26475512" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a OrangerV1
| This area was generated with Dilib version V0.6.25. |  |