A water-soluble bis(thiosemicarbazone) ligand. a sensitive probe and metal buffer for zinc.
Identifieur interne : 000232 ( Main/Corpus ); précédent : 000231; suivant : 000233A water-soluble bis(thiosemicarbazone) ligand. a sensitive probe and metal buffer for zinc.
Auteurs : Gojko Buncic ; Paul S. Donnelly ; Brett M. Paterson ; Jonathan M. White ; Matthias Zimmermann ; Zhiguang Xiao ; Anthony G. WeddSource :
- Inorganic chemistry [ 1520-510X ] ; 2010.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Zinc.
- chemical , chemistry : Thiosemicarbazones, Water.
- chemical , metabolism : Plant Proteins, Zinc.
- chemical : Ligands.
- Models, Molecular, Protein Binding, Solubility.
Abstract
The first member of a water-soluble family of bis(thiosemicarbazone) ligands is reported. It forms a 1:1 complex with Zn(II) that absorbs intensely in the visible region (lambda(max) = 414 nm; epsilon = 1.8(4) x 10(4) M(-1) cm(-1); pH 7.3). Its affinity for Zn(II) (K(D) = 5.9(3) x 10(-9) M at pH 7.3) was determined by competition with ligand ethylene glycol O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid. Its potential application as a chromophoric probe was demonstrated by estimation of the Zn(II) binding affinities of the soluble metal-binding domains of two plant metal-transporting proteins.
DOI: 10.1021/ic902370a
PubMed: 20178320
Links to Exploration step
pubmed:20178320Le document en format XML
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White</name></author><author><name sortKey="Zimmermann, Matthias" sort="Zimmermann, Matthias" uniqKey="Zimmermann M" first="Matthias" last="Zimmermann">Matthias Zimmermann</name></author><author><name sortKey="Xiao, Zhiguang" sort="Xiao, Zhiguang" uniqKey="Xiao Z" first="Zhiguang" last="Xiao">Zhiguang Xiao</name></author><author><name sortKey="Wedd, Anthony G" sort="Wedd, Anthony G" uniqKey="Wedd A" first="Anthony G" last="Wedd">Anthony G. 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Donnelly</name></author><author><name sortKey="Paterson, Brett M" sort="Paterson, Brett M" uniqKey="Paterson B" first="Brett M" last="Paterson">Brett M. Paterson</name></author><author><name sortKey="White, Jonathan M" sort="White, Jonathan M" uniqKey="White J" first="Jonathan M" last="White">Jonathan M. White</name></author><author><name sortKey="Zimmermann, Matthias" sort="Zimmermann, Matthias" uniqKey="Zimmermann M" first="Matthias" last="Zimmermann">Matthias Zimmermann</name></author><author><name sortKey="Xiao, Zhiguang" sort="Xiao, Zhiguang" uniqKey="Xiao Z" first="Zhiguang" last="Xiao">Zhiguang Xiao</name></author><author><name sortKey="Wedd, Anthony G" sort="Wedd, Anthony G" uniqKey="Wedd A" first="Anthony G" last="Wedd">Anthony G. Wedd</name></author></analytic><series><title level="j">Inorganic chemistry</title><idno type="eISSN">1520-510X</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Ligands (MeSH)</term><term>Models, Molecular (MeSH)</term><term>Plant Proteins (metabolism)</term><term>Protein Binding (MeSH)</term><term>Solubility (MeSH)</term><term>Thiosemicarbazones (chemistry)</term><term>Water (chemistry)</term><term>Zinc (analysis)</term><term>Zinc (metabolism)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Zinc</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Thiosemicarbazones</term><term>Water</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Plant Proteins</term><term>Zinc</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Ligands</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Models, Molecular</term><term>Protein Binding</term><term>Solubility</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The first member of a water-soluble family of bis(thiosemicarbazone) ligands is reported. It forms a 1:1 complex with Zn(II) that absorbs intensely in the visible region (lambda(max) = 414 nm; epsilon = 1.8(4) x 10(4) M(-1) cm(-1); pH 7.3). Its affinity for Zn(II) (K(D) = 5.9(3) x 10(-9) M at pH 7.3) was determined by competition with ligand ethylene glycol O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid. Its potential application as a chromophoric probe was demonstrated by estimation of the Zn(II) binding affinities of the soluble metal-binding domains of two plant metal-transporting proteins.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20178320</PMID><DateCompleted><Year>2010</Year><Month>07</Month><Day>13</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1520-510X</ISSN><JournalIssue CitedMedium="Internet"><Volume>49</Volume><Issue>7</Issue><PubDate><Year>2010</Year><Month>Apr</Month><Day>05</Day></PubDate></JournalIssue><Title>Inorganic chemistry</Title><ISOAbbreviation>Inorg Chem</ISOAbbreviation></Journal><ArticleTitle>A water-soluble bis(thiosemicarbazone) ligand. a sensitive probe and metal buffer for zinc.</ArticleTitle><Pagination><MedlinePgn>3071-3</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1021/ic902370a</ELocationID><Abstract><AbstractText>The first member of a water-soluble family of bis(thiosemicarbazone) ligands is reported. It forms a 1:1 complex with Zn(II) that absorbs intensely in the visible region (lambda(max) = 414 nm; epsilon = 1.8(4) x 10(4) M(-1) cm(-1); pH 7.3). Its affinity for Zn(II) (K(D) = 5.9(3) x 10(-9) M at pH 7.3) was determined by competition with ligand ethylene glycol O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid. Its potential application as a chromophoric probe was demonstrated by estimation of the Zn(II) binding affinities of the soluble metal-binding domains of two plant metal-transporting proteins.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Buncic</LastName><ForeName>Gojko</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria 3010, Australia.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Donnelly</LastName><ForeName>Paul S</ForeName><Initials>PS</Initials></Author><Author ValidYN="Y"><LastName>Paterson</LastName><ForeName>Brett M</ForeName><Initials>BM</Initials></Author><Author ValidYN="Y"><LastName>White</LastName><ForeName>Jonathan M</ForeName><Initials>JM</Initials></Author><Author ValidYN="Y"><LastName>Zimmermann</LastName><ForeName>Matthias</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Xiao</LastName><ForeName>Zhiguang</ForeName><Initials>Z</Initials></Author><Author ValidYN="Y"><LastName>Wedd</LastName><ForeName>Anthony G</ForeName><Initials>AG</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Inorg Chem</MedlineTA><NlmUniqueID>0366543</NlmUniqueID><ISSNLinking>0020-1669</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D008024">Ligands</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010940">Plant Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013882">Thiosemicarbazones</NameOfSubstance></Chemical><Chemical><RegistryNumber>059QF0KO0R</RegistryNumber><NameOfSubstance UI="D014867">Water</NameOfSubstance></Chemical><Chemical><RegistryNumber>J41CSQ7QDS</RegistryNumber><NameOfSubstance UI="D015032">Zinc</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D008024" MajorTopicYN="N">Ligands</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008958" MajorTopicYN="N">Models, Molecular</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010940" MajorTopicYN="N">Plant Proteins</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011485" MajorTopicYN="N">Protein Binding</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012995" MajorTopicYN="N">Solubility</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013882" MajorTopicYN="N">Thiosemicarbazones</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014867" MajorTopicYN="N">Water</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015032" MajorTopicYN="N">Zinc</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2010</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2010</Year><Month>2</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>7</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">20178320</ArticleId><ArticleId IdType="doi">10.1021/ic902370a</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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