Why COVID-19 Transmission Is More Efficient and Aggressive Than Viral Transmission in Previous Coronavirus Epidemics?
Identifieur interne : 000002 ( Main/Exploration ); précédent : 000001; suivant : 000003Why COVID-19 Transmission Is More Efficient and Aggressive Than Viral Transmission in Previous Coronavirus Epidemics?
Auteurs : Fatma Elrashdy ; Elrashdy M. Redwan [Arabie saoudite] ; Vladimir N. Uversky [Arabie saoudite, États-Unis, Russie]Source :
- Biomolecules [ 2218-273X ] ; 2020.
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans (HCoVs), which circulate continuously in the human population, but their phenotypes are generally mild, and these HCoVs received relatively little attention. These dramatic differences between infection with HCoVs, SARS-CoV, MERS-CoV, and SARS-CoV-2 raise many questions, such as: Why is COVID-19 transmitted so quickly? Is it due to some specific features of the viral structure? Are there some specific human (host) factors? Are there some environmental factors? The aim of this review is to collect and concisely summarize the possible and logical answers to these questions.
Url:
DOI: 10.3390/biom10091312
PubMed: 32933047
PubMed Central: 7565143
Affiliations:
- Arabie saoudite, Russie, États-Unis
- District fédéral central, Floride
- Moscou, Tampa
- Université de Floride du Sud
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans (HCoVs), which circulate continuously in the human population, but their phenotypes are generally mild, and these HCoVs received relatively little attention. These dramatic differences between infection with HCoVs, SARS-CoV, MERS-CoV, and SARS-CoV-2 raise many questions, such as: Why is COVID-19 transmitted so quickly? Is it due to some specific features of the viral structure? Are there some specific human (host) factors? Are there some environmental factors? The aim of this review is to collect and concisely summarize the possible and logical answers to these questions.</p>
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<author><name sortKey="Coit, P" uniqKey="Coit P">P. Coit</name>
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<author><name sortKey="Lu, Q" uniqKey="Lu Q">Q. Lu</name>
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<affiliations><list><country><li>Arabie saoudite</li>
<li>Russie</li>
<li>États-Unis</li>
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<region><li>District fédéral central</li>
<li>Floride</li>
</region>
<settlement><li>Moscou</li>
<li>Tampa</li>
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<orgName><li>Université de Floride du Sud</li>
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<tree><noCountry><name sortKey="Elrashdy, Fatma" sort="Elrashdy, Fatma" uniqKey="Elrashdy F" first="Fatma" last="Elrashdy">Fatma Elrashdy</name>
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<country name="Arabie saoudite"><noRegion><name sortKey="Redwan, Elrashdy M" sort="Redwan, Elrashdy M" uniqKey="Redwan E" first="Elrashdy M." last="Redwan">Elrashdy M. Redwan</name>
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<name sortKey="Uversky, Vladimir N" sort="Uversky, Vladimir N" uniqKey="Uversky V" first="Vladimir N." last="Uversky">Vladimir N. Uversky</name>
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<country name="États-Unis"><region name="Floride"><name sortKey="Uversky, Vladimir N" sort="Uversky, Vladimir N" uniqKey="Uversky V" first="Vladimir N." last="Uversky">Vladimir N. Uversky</name>
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<country name="Russie"><region name="District fédéral central"><name sortKey="Uversky, Vladimir N" sort="Uversky, Vladimir N" uniqKey="Uversky V" first="Vladimir N." last="Uversky">Vladimir N. Uversky</name>
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