| Ident. | Authors (with country if any) | Title |
|---|
| 000044 (2020) |
Mai Sugahara ; Shinji Tanaka ; Tetsuhiro Tanaka [Japon] ; Hisako Saito ; Yu Ishimoto ; Takeshi Wakashima ; Masatoshi Ueda ; Kenji Fukui ; Akira Shimizu [Japon] ; Reiko Inagi ; Toshimasa Yamauchi [Japon] ; Takashi Kadowaki [Japon] ; Masaomi Nangaku | Prolyl Hydroxylase Domain Inhibitor Protects against Metabolic Disorders and Associated Kidney Disease in Obese Type 2 Diabetic Mice. |
| 000234 (2019) |
Zhen Guo [République populaire de Chine] ; Xiaowei Song [République populaire de Chine] ; Li-Min Zhao [République populaire de Chine] ; Ming Guan Piao [République populaire de Chine] ; Jishan Quan [République populaire de Chine] ; Hu-Ri Piao [République populaire de Chine] ; Cheng Hua Jin [République populaire de Chine] | Synthesis and biological evaluation of novel benzo[c][1,2,5]thiadiazol-5-yl and thieno[3,2-c]- pyridin-2-yl imidazole derivatives as ALK5 inhibitors. |
| 000236 (2019) |
Xiaoqing Song [République populaire de Chine] ; Qianqian Gan [République populaire de Chine] ; Xuran Zhang [République populaire de Chine] ; Junbo Zhang [République populaire de Chine] | Synthesis and Biological Evaluation of Novel 99mTc-Labeled Palbociclib Derivatives Targeting Cyclin-Dependent Kinase 4/6 (CDK4/6) as Potential Cancer Imaging Agents. |
| 000238 (2019) |
Tomohiro Matsumoto [Japon] ; Satomi Kiuchi [Japon] ; Takatoshi Murase [Japon] | Synergistic activation of thermogenic adipocytes by a combination of PPARγ activation, SMAD3 inhibition and adrenergic receptor activation ameliorates metabolic abnormalities in rodents. |
| 000468 (2019) |
Maryam Jamshidi-Aidji [Allemagne] ; Ivica Dimki [Serbie] ; Petar Ristivojevi [Serbie] ; Slaviša Stankovi [Serbie] ; Gertrud E. Morlock [Allemagne] | Effect-directed screening of Bacillus lipopeptide extracts via hyphenated high-performance thin-layer chromatography. |
| 000535 (2019) |
Talveen S. Purba [Royaume-Uni] ; Kayumba Ng'Andu [Royaume-Uni] ; Lars Brunken [Allemagne] ; Eleanor Smart [Royaume-Uni] ; Ellen Mitchell [Royaume-Uni] ; Nashat Hassan [Royaume-Uni] ; Aaron O'Brien [Royaume-Uni] ; Charlotte Mellor [Royaume-Uni] ; Jennifer Jackson [Royaume-Uni] ; Asim Shahmalak [Royaume-Uni] ; Ralf Paus [Royaume-Uni, Allemagne, États-Unis] | CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane-induced alopecia. |
| 000B54 (2017) |
Katarina Bacevic [France] ; Robert Noble [France, Suisse] ; Ahmed Soffar [France, Égypte] ; Orchid Wael Ammar [France] ; Benjamin Boszonyik [France] ; Susana Prieto [France] ; Charles Vincent [France] ; Michael E. Hochberg [France, États-Unis] ; Liliana Krasinska [France] ; Daniel Fisher [France] | Spatial competition constrains resistance to targeted cancer therapy. |
| 000B55 (2017) |
Fotios Mpekris [Chypre (pays)] ; Panagiotis Papageorgis [Chypre (pays)] ; Christiana Polydorou [Chypre (pays)] ; Chrysovalantis Voutouri [Chypre (pays)] ; Maria Kalli [Chypre (pays)] ; Athanassios P. Pirentis [Chypre (pays)] ; Triantafyllos Stylianopoulos [Chypre (pays)] | Sonic-hedgehog pathway inhibition normalizes desmoplastic tumor microenvironment to improve chemo- and nanotherapy. |
| 000D24 (2017) |
Aleksandra Ka Mierczak [Pologne] ; Damian Kusy [Pologne] ; Sanna P. Niinivehmas [Finlande] ; Joanna Gmach [Pologne] ; Łukasz Joachimiak [Pologne] ; Olli T. Pentik Inen [Finlande] ; Edyta Gendaszewska-Darmach [Pologne] ; Katarzyna M. Bła Ewska [Pologne] | Identification of the Privileged Position in the Imidazo[1,2-a]pyridine Ring of Phosphonocarboxylates for Development of Rab Geranylgeranyl Transferase (RGGT) Inhibitors. |
| 000E24 (2017) |
Inan Olmez [États-Unis] ; Breanna Brenneman [États-Unis] ; Aizhen Xiao [États-Unis] ; Vlad Serbulea [États-Unis] ; Mouadh Benamar [États-Unis] ; Ying Zhang [États-Unis] ; Laryssa Manigat [États-Unis] ; Tarek Abbas [États-Unis] ; Jeongwu Lee [États-Unis] ; Ichiro Nakano [États-Unis] ; Jakub Godlewski [États-Unis] ; Agnieszka Bronisz [États-Unis] ; Roger Abounader [États-Unis] ; Norbert Leitinger [États-Unis] ; Benjamin Purow [États-Unis] | Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms. |
| 001425 (2015) |
Cui Liu [République populaire de Chine] ; Jin Chen [République populaire de Chine] ; Entao Li [République populaire de Chine] ; Qiang Fan [République populaire de Chine] ; Deyun Wang [République populaire de Chine] ; Peng Li [République populaire de Chine] ; Xiuping Li [République populaire de Chine] ; Xingying Chen [République populaire de Chine] ; Shulei Qiu [République populaire de Chine] ; Zhenzhen Gao [République populaire de Chine] ; Hongquan Li [République populaire de Chine] ; Yuanliang Hu [République populaire de Chine] | The comparison of antioxidative and hepatoprotective activities of Codonopsis pilosula polysaccharide (CP) and sulfated CP. |
| 001540 (2015) |
Lei Yu [République populaire de Chine] ; Xiao-Yang Zhang ; Zhang-Peng Chen ; Qian-Xing Zhuang ; Jing-Ning Zhu ; Jian-Jun Wang | Orexin excites rat inferior vestibular nuclear neurons via co-activation of OX1 and OX 2 receptors. |
| 001574 (2015) |
Yuanyuan Zhao [République populaire de Chine] ; Jing Zhang [République populaire de Chine] ; Ying Tian [République populaire de Chine] ; Cong Xue [République populaire de Chine] ; Zhihuang Hu [République populaire de Chine] ; Li Zhang [République populaire de Chine] | Met tyrosine kinase inhibitor, PF-2341066, suppresses growth and invasion of nasopharyngeal carcinoma. |
| 001698 (2015) |
Yu Jiao [République populaire de Chine] ; Bo-Tao Xin [Pays-Bas] ; Yanmin Zhang [République populaire de Chine] ; Jianbing Wu [République populaire de Chine] ; Xiaolin Lu [République populaire de Chine] ; Ying Zheng [République populaire de Chine] ; Weifang Tang [République populaire de Chine] ; Xiang Zhou [République populaire de Chine] | Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents. |
| 001721 (2015) |
John L. Pilon [États-Unis] ; Dane J. Clausen ; Ryan J. Hansen ; Paul J. Lunghofer ; Brad Charles ; Barbara J. Rose ; Douglas H. Thamm ; Daniel L. Gustafson ; James E. Bradner ; Robert M. Williams | Comparative pharmacokinetic properties and antitumor activity of the marine HDACi Largazole and Largazole peptide isostere. |
| 001818 (2015) |
Koushambi Mitra [Inde] ; Shilpa Patil ; Paturu Kondaiah ; Akhil R. Chakravarty | 2-(Phenylazo)pyridineplatinum(II) catecholates showing photocytotoxicity, nuclear uptake, and glutathione-triggered ligand release. |
| 001845 (2014) |
Graziela N. Hagihara [Brésil] ; Nubia S. Lobato [Brésil] ; Fernando P. Filgueira [Brésil] ; Eliana H. Akamine [Brésil] ; Danielle S. Aragão [Brésil] ; Dulce E. Casarini [Brésil] ; Maria Helena C. Carvalho [Brésil] ; Zuleica B. Fortes [Brésil] | Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats. |
| 001A25 (2014) |
Flore Dossou-Yovo [France] ; Godefroy Mamadou [France] ; Imar Djibrine Soudy [Tchad] ; Nicolas Limas-Nzouzi [France] ; Joe Miantezila [France] ; Jehan-François Desjeux [France] ; Bruno Eto [France] | Metronidazole or Cotrimoxazole therapy is associated with a decrease in intestinal bioavailability of common antiretroviral drugs. |
| 001A65 (2014) |
Karla L. Guarido [Brésil] ; Ronald P M. Gonçalves ; Arquimedes Gasparotto Júnior ; José Eduardo Da Silva-Santos | Increased activation of the Rho-A/Rho-kinase pathway in the renal vascular system is responsible for the enhanced reactivity to exogenous vasopressin in endotoxemic rats. |
| 001A68 (2014) |
Yasuhiko Kubota [Japon] ; Shigeru Miyagawa [Japon] ; Satsuki Fukushima [Japon] ; Atsuhiro Saito [Japon] ; Hiroshi Watabe [Japon] ; Takashi Daimon [Japon] ; Yoshiki Sakai [Japon] ; Toshiaki Akita [Japon] ; Yoshiki Sawa [Japon] | Impact of cardiac support device combined with slow-release prostacyclin agonist in a canine ischemic cardiomyopathy model. |
| 001A73 (2014) |
Jodi Dufner-Beattie [États-Unis] ; Andrew O'Guin [États-Unis] ; Stephanie O'Guin [États-Unis] ; Aaron Briley [États-Unis] ; Bin Wang [États-Unis] ; Jennifer Balsarotti [États-Unis] ; Robert Roth [États-Unis] ; Gale Starkey [États-Unis] ; Urszula Slomczynska [États-Unis] ; Amine Noueiry [États-Unis] ; Paul D. Olivo [États-Unis] ; Charles M. Rice [États-Unis] | Identification of AP80978, a novel small-molecule inhibitor of hepatitis C virus replication that targets NS4B. |
