GEO-PGS composite shows synergistic and complementary effect on Escherichia coli and improvement of intestinal dysfunction.
Identifieur interne : 000095 ( Main/Exploration ); précédent : 000094; suivant : 000096GEO-PGS composite shows synergistic and complementary effect on Escherichia coli and improvement of intestinal dysfunction.
Auteurs : Na Xu [République populaire de Chine] ; Renjie Zhou [République populaire de Chine] ; Qian Jiang [République populaire de Chine] ; Lingyan Kong [République populaire de Chine] ; Hong Lei [République populaire de Chine]Source :
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [ 1873-6351 ] ; 2020.
Descripteurs français
- KwdFr :
- Animaux (MeSH), Antibactériens (usage thérapeutique), Composés du magnésium (usage thérapeutique), Composés du silicium (usage thérapeutique), Cytokines (génétique), Cytokines (métabolisme), Entérite (microbiologie), Entérite (traitement médicamenteux), Escherichia coli (effets des médicaments et des substances chimiques), Expression des gènes (effets des médicaments et des substances chimiques), Gingembre (composition chimique), Huile essentielle (usage thérapeutique), Intestin grêle (anatomopathologie), Intestin grêle (effets des médicaments et des substances chimiques), Souris (MeSH), Synergie des médicaments (MeSH), Tests de sensibilité microbienne (MeSH).
- MESH :
- anatomopathologie : Intestin grêle.
- composition chimique : Gingembre.
- effets des médicaments et des substances chimiques : Escherichia coli, Expression des gènes, Intestin grêle.
- génétique : Cytokines.
- microbiologie : Entérite.
- métabolisme : Cytokines.
- traitement médicamenteux : Entérite.
- usage thérapeutique : Antibactériens, Composés du magnésium, Composés du silicium, Huile essentielle.
- Animaux, Souris, Synergie des médicaments, Tests de sensibilité microbienne.
English descriptors
- KwdEn :
- Animals (MeSH), Anti-Bacterial Agents (therapeutic use), Cytokines (genetics), Cytokines (metabolism), Drug Synergism (MeSH), Enteritis (drug therapy), Enteritis (microbiology), Escherichia coli (drug effects), Gene Expression (drug effects), Ginger (chemistry), Intestine, Small (drug effects), Intestine, Small (pathology), Magnesium Compounds (therapeutic use), Mice (MeSH), Microbial Sensitivity Tests (MeSH), Oils, Volatile (therapeutic use), Silicon Compounds (therapeutic use).
- MESH :
- chemical , genetics : Cytokines.
- chemical , metabolism : Cytokines.
- chemical , therapeutic use : Anti-Bacterial Agents, Magnesium Compounds, Oils, Volatile, Silicon Compounds.
- chemistry : Ginger.
- drug effects : Escherichia coli, Gene Expression, Intestine, Small.
- drug therapy : Enteritis.
- microbiology : Enteritis.
- pathology : Intestine, Small.
- Animals, Drug Synergism, Mice, Microbial Sensitivity Tests.
Abstract
Palygorskite (PGS) is a kind of clay minerals with the property of absorbent capacity, and ginger essential oil (GEO) is a kind of natural antibacterial substances. In the present study PGS was used as carrier of GEO, and thus, a kind of new anti-bacterial composite GEO-PGS has been obtained. Characterization, inhibitory effect of GEO-PGS on Escherichia coli (E. coli) and its function of improvement of intestinal health would be investigated. Results showed that characterization analysis of GEO-PGS (FTIR, TG-DSC, BET, Zeta potential, specific surface area, total pore volume and size, TEM observation) demonstrated combination of GEO and PGS, and GEO was absorbed on the surface of PGS, partially filled the micropores of PGS. GEO-PGS had obvious inhibitory effect on E.coli, in combination of the antibacterial activity of GEO and bacteria-absorbed capability of PGS. GEO-PGS also had ameliorating effect on enteritis and intestinal dysfunction in vivo, which might be related to the inhibition of gene expression of inflammatory cytokines (TLR2, IL-6, TNFα, and IL-8). In conclusion, the novel composite GEO-PGS has the potential usage as functional component having effect of improving intestinal health.
DOI: 10.1016/j.fct.2019.110936
PubMed: 31682933
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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In the present study PGS was used as carrier of GEO, and thus, a kind of new anti-bacterial composite GEO-PGS has been obtained. Characterization, inhibitory effect of GEO-PGS on Escherichia coli (E. coli) and its function of improvement of intestinal health would be investigated. Results showed that characterization analysis of GEO-PGS (FTIR, TG-DSC, BET, Zeta potential, specific surface area, total pore volume and size, TEM observation) demonstrated combination of GEO and PGS, and GEO was absorbed on the surface of PGS, partially filled the micropores of PGS. GEO-PGS had obvious inhibitory effect on E.coli, in combination of the antibacterial activity of GEO and bacteria-absorbed capability of PGS. GEO-PGS also had ameliorating effect on enteritis and intestinal dysfunction in vivo, which might be related to the inhibition of gene expression of inflammatory cytokines (TLR2, IL-6, TNF<sub>α</sub>, and IL-8). In conclusion, the novel composite GEO-PGS has the potential usage as functional component having effect of improving intestinal health.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">31682933</PMID><DateCompleted><Year>2020</Year><Month>01</Month><Day>27</Day></DateCompleted><DateRevised><Year>2020</Year><Month>01</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-6351</ISSN><JournalIssue CitedMedium="Internet"><Volume>135</Volume><PubDate><Year>2020</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association</Title><ISOAbbreviation>Food Chem Toxicol</ISOAbbreviation></Journal><ArticleTitle>GEO-PGS composite shows synergistic and complementary effect on Escherichia coli and improvement of intestinal dysfunction.</ArticleTitle><Pagination><MedlinePgn>110936</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S0278-6915(19)30726-4</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.fct.2019.110936</ELocationID><Abstract><AbstractText>Palygorskite (PGS) is a kind of clay minerals with the property of absorbent capacity, and ginger essential oil (GEO) is a kind of natural antibacterial substances. In the present study PGS was used as carrier of GEO, and thus, a kind of new anti-bacterial composite GEO-PGS has been obtained. Characterization, inhibitory effect of GEO-PGS on Escherichia coli (E. coli) and its function of improvement of intestinal health would be investigated. Results showed that characterization analysis of GEO-PGS (FTIR, TG-DSC, BET, Zeta potential, specific surface area, total pore volume and size, TEM observation) demonstrated combination of GEO and PGS, and GEO was absorbed on the surface of PGS, partially filled the micropores of PGS. GEO-PGS had obvious inhibitory effect on E.coli, in combination of the antibacterial activity of GEO and bacteria-absorbed capability of PGS. GEO-PGS also had ameliorating effect on enteritis and intestinal dysfunction in vivo, which might be related to the inhibition of gene expression of inflammatory cytokines (TLR2, IL-6, TNF<sub>α</sub>, and IL-8). In conclusion, the novel composite GEO-PGS has the potential usage as functional component having effect of improving intestinal health.</AbstractText><CopyrightInformation>Copyright © 2019 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Xu</LastName><ForeName>Na</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>College of Food Science and Engineering / Collaborative Innovation Center for Modern Grain Circulation and Safety / Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing, 210023, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhou</LastName><ForeName>Renjie</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>School of Food and Biological Engineering, Hefei University of Technology, Hefei, 230009, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>Qian</ForeName><Initials>Q</Initials><AffiliationInfo><Affiliation>College of Food Science and Engineering / Collaborative Innovation Center for Modern Grain Circulation and Safety / Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing, 210023, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kong</LastName><ForeName>Lingyan</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>College of Food Science and Engineering / Collaborative Innovation Center for Modern Grain Circulation and Safety / Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing, 210023, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lei</LastName><ForeName>Hong</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>College of Food Science and Engineering / Collaborative Innovation Center for Modern Grain Circulation and Safety / Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing University of Finance and Economics, Nanjing, 210023, China. Electronic address: leihong56@163.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2019</Year><Month>11</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Food Chem Toxicol</MedlineTA><NlmUniqueID>8207483</NlmUniqueID><ISSNLinking>0278-6915</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016207">Cytokines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017616">Magnesium Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D009822">Oils, Volatile</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D017655">Silicon Compounds</NameOfSubstance></Chemical><Chemical><RegistryNumber>U6V729APAM</RegistryNumber><NameOfSubstance UI="C026325">attapulgite</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016207" MajorTopicYN="N">Cytokines</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004357" MajorTopicYN="N">Drug Synergism</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004751" MajorTopicYN="N">Enteritis</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName><QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004926" MajorTopicYN="N">Escherichia coli</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015870" MajorTopicYN="N">Gene Expression</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020939" MajorTopicYN="N">Ginger</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007421" MajorTopicYN="N">Intestine, Small</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017616" MajorTopicYN="N">Magnesium Compounds</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D051379" MajorTopicYN="N">Mice</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008826" MajorTopicYN="N">Microbial Sensitivity Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009822" MajorTopicYN="N">Oils, Volatile</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017655" MajorTopicYN="N">Silicon Compounds</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Anti-bacterial effect</Keyword><Keyword MajorTopicYN="N">Characterization</Keyword><Keyword MajorTopicYN="N">Escherichia coli</Keyword><Keyword MajorTopicYN="N">Ginger essential oil-Palygorskite composite</Keyword><Keyword MajorTopicYN="N">Intestinal health</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year><Month>09</Month><Day>17</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2019</Year><Month>10</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2019</Year><Month>10</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2019</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>1</Month><Day>28</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2019</Year><Month>11</Month><Day>5</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">31682933</ArticleId><ArticleId IdType="pii">S0278-6915(19)30726-4</ArticleId><ArticleId IdType="doi">10.1016/j.fct.2019.110936</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Xu, Na" sort="Xu, Na" uniqKey="Xu N" first="Na" last="Xu">Na Xu</name></noRegion><name sortKey="Jiang, Qian" sort="Jiang, Qian" uniqKey="Jiang Q" first="Qian" last="Jiang">Qian Jiang</name><name sortKey="Kong, Lingyan" sort="Kong, Lingyan" uniqKey="Kong L" first="Lingyan" last="Kong">Lingyan Kong</name><name sortKey="Lei, Hong" sort="Lei, Hong" uniqKey="Lei H" first="Hong" last="Lei">Hong Lei</name><name sortKey="Zhou, Renjie" sort="Zhou, Renjie" uniqKey="Zhou R" first="Renjie" last="Zhou">Renjie Zhou</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Bois/explor/BiopestPeptidV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000095 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000095 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Bois
|area= BiopestPeptidV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:31682933
|texte= GEO-PGS composite shows synergistic and complementary effect on Escherichia coli and improvement of intestinal dysfunction.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:31682933" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a BiopestPeptidV1
| This area was generated with Dilib version V0.6.38. |  |